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Volumn 32, Issue 26, 2011, Pages 6164-6173

Mechanism and consequence of chitosan-mediated reversible epithelial tight junction opening

Author keywords

Chitosan; Claudin 4; Epithelial cell; Paracellular transport; Tight junction

Indexed keywords

CACO-2 CELLS; CLAUDIN-4; CONTRIBUTING FACTOR; EPITHELIAL CELLS; FURTHER DEVELOPMENT; GENE TRANSCRIPTIONS; HYDROPHILIC MACROMOLECULES; MOLECULAR LEVELS; PARACELLULAR PERMEABILITY; PARACELLULAR TRANSPORT; PERMEATION ENHANCERS; PROTEIN EXPRESSION LEVELS; PROTEIN SYNTHESIS; SMALL INTESTINE; TIGHT JUNCTIONS; TRANSMEMBRANES;

EID: 79959876473     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.03.056     Document Type: Article
Times cited : (296)

References (41)
  • 1
    • 78249241188 scopus 로고    scopus 로고
    • Self-assembled pH-sensitive nanoparticles: a platform for oral delivery of protein drugs
    • Sonaje K., Lin K.J., Wang J.J., Mi F.L., Chen C.T., Juang J.H., et al. Self-assembled pH-sensitive nanoparticles: a platform for oral delivery of protein drugs. Adv Funct Mater 2010, 20:3695-3700.
    • (2010) Adv Funct Mater , vol.20 , pp. 3695-3700
    • Sonaje, K.1    Lin, K.J.2    Wang, J.J.3    Mi, F.L.4    Chen, C.T.5    Juang, J.H.6
  • 2
    • 0345055299 scopus 로고    scopus 로고
    • Comparison of the effect of different chitosan salts and N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2)
    • Kotzé A.F., Luessen H.L., de Leeuw B.J., de Boer A.G., Verhoef J.C., Junginger H.E. Comparison of the effect of different chitosan salts and N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2). J Control Release 1998, 51:35-46.
    • (1998) J Control Release , vol.51 , pp. 35-46
    • Kotzé, A.F.1    Luessen, H.L.2    de Leeuw, B.J.3    de Boer, A.G.4    Verhoef, J.C.5    Junginger, H.E.6
  • 3
    • 0029167043 scopus 로고
    • Regulation of tight-junction permeability during nutrient absorption across the intestinal epithelium
    • Ballard S.T., Hunter J.H., Taylor A.E. Regulation of tight-junction permeability during nutrient absorption across the intestinal epithelium. Annu Rev Nutr 1995, 15:35-55.
    • (1995) Annu Rev Nutr , vol.15 , pp. 35-55
    • Ballard, S.T.1    Hunter, J.H.2    Taylor, A.E.3
  • 4
    • 19444373410 scopus 로고    scopus 로고
    • θ Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability
    • Banan A., Zhang L.J., Shaikh M., Fields J.Z., Choudhary S., Forsyth C.B., et al. θ Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability. Pharmacol Exp Ther 2005, 313:962-982.
    • (2005) Pharmacol Exp Ther , vol.313 , pp. 962-982
    • Banan, A.1    Zhang, L.J.2    Shaikh, M.3    Fields, J.Z.4    Choudhary, S.5    Forsyth, C.B.6
  • 5
    • 0344465840 scopus 로고    scopus 로고
    • Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase
    • Stamatovic S.M., Keep R.F., Kunkel S.L., Andjelkovic A.V. Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase. J Cell Sci 2003, 116:4615-4628.
    • (2003) J Cell Sci , vol.116 , pp. 4615-4628
    • Stamatovic, S.M.1    Keep, R.F.2    Kunkel, S.L.3    Andjelkovic, A.V.4
  • 7
    • 67650306418 scopus 로고    scopus 로고
    • Protein phosphatase 2A plays a role in hydrogen peroxide-induced disruption of tight junctions in Caco-2 cell monolayers
    • Sheth P., Samak G., Shull J.A., Seth A., Rao R. Protein phosphatase 2A plays a role in hydrogen peroxide-induced disruption of tight junctions in Caco-2 cell monolayers. Biochem J 2009, 421:59-70.
    • (2009) Biochem J , vol.421 , pp. 59-70
    • Sheth, P.1    Samak, G.2    Shull, J.A.3    Seth, A.4    Rao, R.5
  • 8
    • 0034599992 scopus 로고    scopus 로고
    • Pores in the wall: claudins constitute tight junction strands containing aqueous pores
    • Tsukita S., Furuse M. Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol 2000, 149:13-16.
    • (2000) J Cell Biol , vol.149 , pp. 13-16
    • Tsukita, S.1    Furuse, M.2
  • 9
    • 0035478758 scopus 로고    scopus 로고
    • Chitosan and its derivatives as intestinal absorption enhancers
    • Thanou M., Verhoef J.C., Junginger H.E. Chitosan and its derivatives as intestinal absorption enhancers. Adv Drug Deliv Rev 2001, 50(Suppl. 1):S91-S101.
    • (2001) Adv Drug Deliv Rev , vol.50 , Issue.SUPPL. 1
    • Thanou, M.1    Verhoef, J.C.2    Junginger, H.E.3
  • 10
    • 0035813752 scopus 로고    scopus 로고
    • Oral drug absorption enhancement by chitosan and its derivatives
    • Thanou M., Verhoef J.C., Junginger H.E. Oral drug absorption enhancement by chitosan and its derivatives. Adv Drug Deliv Rev 2001, 52:117-126.
    • (2001) Adv Drug Deliv Rev , vol.52 , pp. 117-126
    • Thanou, M.1    Verhoef, J.C.2    Junginger, H.E.3
  • 11
    • 60849130683 scopus 로고    scopus 로고
    • In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery
    • Sonaje K., Lin Y.H., Juang J.H., Wey S.P., Chen C.T., Sung H.W. In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery. Biomaterials 2009, 30:2329-2339.
    • (2009) Biomaterials , vol.30 , pp. 2329-2339
    • Sonaje, K.1    Lin, Y.H.2    Juang, J.H.3    Wey, S.P.4    Chen, C.T.5    Sung, H.W.6
  • 12
    • 26644447977 scopus 로고    scopus 로고
    • Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems
    • Takeuchi H., Thongborisute J., Matsui Y., Sugihara H., Yamamoto H., Kawashima Y. Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems. Adv Drug Deliv Rev 2005, 57:1583-1594.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1583-1594
    • Takeuchi, H.1    Thongborisute, J.2    Matsui, Y.3    Sugihara, H.4    Yamamoto, H.5    Kawashima, Y.6
  • 13
    • 76749103819 scopus 로고    scopus 로고
    • Enteric-coated capsules filled with freeze-dried chitosan/poly(gamma-glutamic acid) nanoparticles for oral insulin delivery
    • Sonaje K., Chen Y.J., Chen H.L., Wey S.P., Juang J.H., Nguyen H.N., et al. Enteric-coated capsules filled with freeze-dried chitosan/poly(gamma-glutamic acid) nanoparticles for oral insulin delivery. Biomaterials 2010, 31:3384-3394.
    • (2010) Biomaterials , vol.31 , pp. 3384-3394
    • Sonaje, K.1    Chen, Y.J.2    Chen, H.L.3    Wey, S.P.4    Juang, J.H.5    Nguyen, H.N.6
  • 14
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmacological excipient
    • Illum R. Chitosan and its use as a pharmacological excipient. Pharm Res 1998, 15:1326-1331.
    • (1998) Pharm Res , vol.15 , pp. 1326-1331
    • Illum, R.1
  • 17
    • 0031774452 scopus 로고    scopus 로고
    • Evaluation of oxprenolol hydrochloride permeation through isolated human skin and pharmacodynamic effect in rats
    • Bolgul Y., Hekimoglu S., Sahin-Erdemli I., Kas H. Evaluation of oxprenolol hydrochloride permeation through isolated human skin and pharmacodynamic effect in rats. STP Pharma Sci 1998, 8:197-201.
    • (1998) STP Pharma Sci , vol.8 , pp. 197-201
    • Bolgul, Y.1    Hekimoglu, S.2    Sahin-Erdemli, I.3    Kas, H.4
  • 18
    • 78349309344 scopus 로고    scopus 로고
    • Mechanisms of cellular uptake and intracellular trafficking with chitosan/DNA/poly(γ-glutamic acid) complexes as a gene delivery vector
    • Peng S.F., Tseng M.T., Ho Y.C., Wei M.C., Liao Z.X., Sung H.W. Mechanisms of cellular uptake and intracellular trafficking with chitosan/DNA/poly(γ-glutamic acid) complexes as a gene delivery vector. Biomaterials 2011, 32:239-248.
    • (2011) Biomaterials , vol.32 , pp. 239-248
    • Peng, S.F.1    Tseng, M.T.2    Ho, Y.C.3    Wei, M.C.4    Liao, Z.X.5    Sung, H.W.6
  • 19
    • 77954385916 scopus 로고    scopus 로고
    • Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: oral delivery using pH-responsive nanoparticles vs. subcutaneous injection
    • Sonaje K., Lin K.J., Wey S.P., Lin C.K., Yeh T.H., Nguyen H.N., et al. Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: oral delivery using pH-responsive nanoparticles vs. subcutaneous injection. Biomaterials 2010, 31:6849-6858.
    • (2010) Biomaterials , vol.31 , pp. 6849-6858
    • Sonaje, K.1    Lin, K.J.2    Wey, S.P.3    Lin, C.K.4    Yeh, T.H.5    Nguyen, H.N.6
  • 20
    • 70349784917 scopus 로고    scopus 로고
    • The characteristics, biodistribution and bioavailability of a chitosan-based nanoparticulate system for the oral delivery of heparin
    • Chen M.C., Wong H.S., Lin K.J., Chen H.L., Wey S.P., Sonaje K., et al. The characteristics, biodistribution and bioavailability of a chitosan-based nanoparticulate system for the oral delivery of heparin. Biomaterials 2009, 30:6629-6637.
    • (2009) Biomaterials , vol.30 , pp. 6629-6637
    • Chen, M.C.1    Wong, H.S.2    Lin, K.J.3    Chen, H.L.4    Wey, S.P.5    Sonaje, K.6
  • 21
    • 77957298626 scopus 로고    scopus 로고
    • Enhancement of efficiencies of the cellular uptake and gene silencing of chitosan/siRNA complexes via the inclusion of a negatively charged poly(γ-glutamic acid)
    • Liao Z.X., Ho Y.C., Chen H.L., Peng S.F., Hsiao C.W., Sung H.W. Enhancement of efficiencies of the cellular uptake and gene silencing of chitosan/siRNA complexes via the inclusion of a negatively charged poly(γ-glutamic acid). Biomaterials 2010, 31:8780-8788.
    • (2010) Biomaterials , vol.31 , pp. 8780-8788
    • Liao, Z.X.1    Ho, Y.C.2    Chen, H.L.3    Peng, S.F.4    Hsiao, C.W.5    Sung, H.W.6
  • 22
    • 0032917517 scopus 로고    scopus 로고
    • Effect of Caco-2 on epithelial permeability and structure
    • Dodane V., Amin Khan M., Merwin J. Effect of Caco-2 on epithelial permeability and structure. Int J Pharm 1999, 182:21-32.
    • (1999) Int J Pharm , vol.182 , pp. 21-32
    • Dodane, V.1    Amin Khan, M.2    Merwin, J.3
  • 23
    • 1642579659 scopus 로고    scopus 로고
    • Effect of chitosan on epithelial cell tight junctions
    • Smith J., Dornish M., Wood E.J. Effect of chitosan on epithelial cell tight junctions. Pharm Res 2004, 21:43-49.
    • (2004) Pharm Res , vol.21 , pp. 43-49
    • Smith, J.1    Dornish, M.2    Wood, E.J.3
  • 24
    • 10644263255 scopus 로고    scopus 로고
    • Involvement of protein kinase C in chitosan glutamate-mediated tight junction disruption
    • Smith J.M., Dornish M., Wood E.J. Involvement of protein kinase C in chitosan glutamate-mediated tight junction disruption. Biomaterials 2005, 26:3269-3276.
    • (2005) Biomaterials , vol.26 , pp. 3269-3276
    • Smith, J.M.1    Dornish, M.2    Wood, E.J.3
  • 25
    • 79251593382 scopus 로고    scopus 로고
    • The glucose-lowering potential of exendin-4 orally delivered via a pH-sensitive nanoparticle vehicle and effects on subsequent insulin secretion in vivo
    • Nguyen H.N., Wey S.P., Juang J.H., Sonaje K., Ho Y.C., Chuang E.Y., et al. The glucose-lowering potential of exendin-4 orally delivered via a pH-sensitive nanoparticle vehicle and effects on subsequent insulin secretion in vivo. Biomaterials 2011, 32:2673-2682.
    • (2011) Biomaterials , vol.32 , pp. 2673-2682
    • Nguyen, H.N.1    Wey, S.P.2    Juang, J.H.3    Sonaje, K.4    Ho, Y.C.5    Chuang, E.Y.6
  • 26
    • 0022509516 scopus 로고
    • The human colon carcinoma cell lines HT-29 and Caco-2: two in vitro models for the study of intestinal differentiation
    • Rousset M. The human colon carcinoma cell lines HT-29 and Caco-2: two in vitro models for the study of intestinal differentiation. Biochimie 1986, 68:1035-1040.
    • (1986) Biochimie , vol.68 , pp. 1035-1040
    • Rousset, M.1
  • 27
    • 0022617544 scopus 로고
    • Crypt cell antigen expression in human colon tumor cell lines: analysis with a panel of monoclonal antibodies to CaCo-2 luminal membrane components
    • Quaroni A. Crypt cell antigen expression in human colon tumor cell lines: analysis with a panel of monoclonal antibodies to CaCo-2 luminal membrane components. J Natl Cancer Inst 1986, 76:571-585.
    • (1986) J Natl Cancer Inst , vol.76 , pp. 571-585
    • Quaroni, A.1
  • 28
    • 0022467958 scopus 로고
    • Expression of developmentally regulated crypt cell antigens in human and rat intestinal tumors
    • Quaroni A., Weiser M.M., Lee S., Amodeo D. Expression of developmentally regulated crypt cell antigens in human and rat intestinal tumors. J Natl Cancer Inst 1986, 77:405-415.
    • (1986) J Natl Cancer Inst , vol.77 , pp. 405-415
    • Quaroni, A.1    Weiser, M.M.2    Lee, S.3    Amodeo, D.4
  • 29
    • 17644385834 scopus 로고    scopus 로고
    • In vitro and ex vivo intestinal tissue models to measure mucoadhesion of poly (methacrylate) and N-trimethylated chitosan polymers
    • Keely S., Rullay A., Wilson C., Carmichael A., Carrington S., Corfield A., et al. In vitro and ex vivo intestinal tissue models to measure mucoadhesion of poly (methacrylate) and N-trimethylated chitosan polymers. Pharm Res 2005, 22:38-49.
    • (2005) Pharm Res , vol.22 , pp. 38-49
    • Keely, S.1    Rullay, A.2    Wilson, C.3    Carmichael, A.4    Carrington, S.5    Corfield, A.6
  • 30
    • 53849143927 scopus 로고    scopus 로고
    • Mucoadhesive microspheres for gastroretentive delivery of acyclovir: in vitro and in vivo evaluation
    • Dhaliwal S., Jain S., Singh H.P., Tiwary A.K. Mucoadhesive microspheres for gastroretentive delivery of acyclovir: in vitro and in vivo evaluation. AAPS J 2008, 10:322-330.
    • (2008) AAPS J , vol.10 , pp. 322-330
    • Dhaliwal, S.1    Jain, S.2    Singh, H.P.3    Tiwary, A.K.4
  • 31
    • 0033078948 scopus 로고    scopus 로고
    • Synthesis of a fluorescent chitosan derivative and its application for the study of chitosan-mucin interactions
    • Qaqish R.B., Amiji M.M. Synthesis of a fluorescent chitosan derivative and its application for the study of chitosan-mucin interactions. Carbohydr Polym 1999, 38:99-107.
    • (1999) Carbohydr Polym , vol.38 , pp. 99-107
    • Qaqish, R.B.1    Amiji, M.M.2
  • 32
    • 36549082939 scopus 로고    scopus 로고
    • The use of biodegradable polymeric nanoparticles in combination with a low-pressure gene gun for transdermal DNA delivery
    • Lee P.W., Peng S.F., Su C.J., Mi F.L., Chen H.L., Wei M.C., et al. The use of biodegradable polymeric nanoparticles in combination with a low-pressure gene gun for transdermal DNA delivery. Biomaterials 2008, 29:742-751.
    • (2008) Biomaterials , vol.29 , pp. 742-751
    • Lee, P.W.1    Peng, S.F.2    Su, C.J.3    Mi, F.L.4    Chen, H.L.5    Wei, M.C.6
  • 33
    • 79959917082 scopus 로고    scopus 로고
    • Biodegradable nanoparticles - a novel approach for oral administration of biological products
    • Prusty A.K., Sahu S.K. Biodegradable nanoparticles - a novel approach for oral administration of biological products. Int J Pharm Sci Nanotech 2009, 2:503-508.
    • (2009) Int J Pharm Sci Nanotech , vol.2 , pp. 503-508
    • Prusty, A.K.1    Sahu, S.K.2
  • 34
    • 56649089693 scopus 로고    scopus 로고
    • Multi-ion-crosslinked nanoparticles with pH-responsive characteristics for oral delivery of protein drugs
    • Lin Y.H., Sonaje K., Lin K.M., Juang J.H., Mi F.L., Yang H.W., et al. Multi-ion-crosslinked nanoparticles with pH-responsive characteristics for oral delivery of protein drugs. J Control Release 2008, 132:141-149.
    • (2008) J Control Release , vol.132 , pp. 141-149
    • Lin, Y.H.1    Sonaje, K.2    Lin, K.M.3    Juang, J.H.4    Mi, F.L.5    Yang, H.W.6
  • 35
    • 0037336565 scopus 로고    scopus 로고
    • Signalling to and from tight junctions
    • Matter K., Balda M. Signalling to and from tight junctions. Nat Rev Mol Cell Biol 2003, 4:225-237.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 225-237
    • Matter, K.1    Balda, M.2
  • 36
    • 56349169898 scopus 로고    scopus 로고
    • Molecular mechanism of intestinal permeability: interaction at tight junctions
    • Hossain Z., Hirata T. Molecular mechanism of intestinal permeability: interaction at tight junctions. Mol Biosyst 2008, 4:1181-1185.
    • (2008) Mol Biosyst , vol.4 , pp. 1181-1185
    • Hossain, Z.1    Hirata, T.2
  • 37
    • 0035102580 scopus 로고    scopus 로고
    • The roles of claudin superfamily proteins in paracellular transport
    • Heiskala M., Peterson P.A., Yang Y. The roles of claudin superfamily proteins in paracellular transport. Traffic 2001, 2:93-98.
    • (2001) Traffic , vol.2 , pp. 93-98
    • Heiskala, M.1    Peterson, P.A.2    Yang, Y.3
  • 38
    • 0037128938 scopus 로고    scopus 로고
    • Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice
    • Furuse M., Hata M., Furuse K., Yoshida Y., Haratake A., Sugitani Y., et al. Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol 2002, 156:1099-1111.
    • (2002) J Cell Biol , vol.156 , pp. 1099-1111
    • Furuse, M.1    Hata, M.2    Furuse, K.3    Yoshida, Y.4    Haratake, A.5    Sugitani, Y.6
  • 39
    • 0021723696 scopus 로고
    • Control of protein degradation and growth phase in normal and neoplastic cells
    • Baccino F.M., Tessitore L., Bonelli G. Control of protein degradation and growth phase in normal and neoplastic cells. Toxicol Pathol 1984, 12:281-287.
    • (1984) Toxicol Pathol , vol.12 , pp. 281-287
    • Baccino, F.M.1    Tessitore, L.2    Bonelli, G.3
  • 40
    • 0036156444 scopus 로고    scopus 로고
    • Actin dependence of polarized receptor recycling in Madin-Darby canine kidney cell endosomes
    • Sheff D.R., Kroschewski R., Mellman I. Actin dependence of polarized receptor recycling in Madin-Darby canine kidney cell endosomes. Mol Biol Cell 2002, 13:262-275.
    • (2002) Mol Biol Cell , vol.13 , pp. 262-275
    • Sheff, D.R.1    Kroschewski, R.2    Mellman, I.3
  • 41
    • 66149122202 scopus 로고    scopus 로고
    • West nile virus capsid degradation of claudin proteins disrupts epithelial barrier function
    • Medigeshi G.R., Hirsch A.J., Brien J.D., Uhrlaub J.L., Mason P.W., Wiley C., et al. West nile virus capsid degradation of claudin proteins disrupts epithelial barrier function. J Virol 2009, 83:6125-6134.
    • (2009) J Virol , vol.83 , pp. 6125-6134
    • Medigeshi, G.R.1    Hirsch, A.J.2    Brien, J.D.3    Uhrlaub, J.L.4    Mason, P.W.5    Wiley, C.6


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