Oral drug absorption enhancement by chitosan and its derivatives

Advanced Drug Delivery Reviews

Volumn 52, Issue 2, 2001, Pages 117-126

  Thanou, M ^a   Verhoef, J C ^a   Junginger, H E ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Absorption enhancers; Chitosan; Low molecular weight heparin; Mono carboxymethylated chitosan (MCC); Peptide drugs; Trimethyl chitosan chloride (TMC)

Indexed keywords

ABSORPTION; BIOLOGICAL MEMBRANES; HYDROPHILICITY; POLYMERS; PROTEINS; TISSUE;

PARACELLULAR PERMEABILITY;

DRUG PRODUCTS;

BUSERELIN; CARBOMER; CHITOSAN; CHITOSAN DERIVATIVE; LOW MOLECULAR WEIGHT HEPARIN; MONOCARBOXYMETHYLCHITOSAN; OCTREOTIDE; TRIMETHYLCHITOSAN CHLORIDE; UNCLASSIFIED DRUG;

CELL MEMBRANE; CELL VIABILITY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG MECHANISM; DRUG PENETRATION; DRUG SAFETY; DRUG SOLUBILITY; DRUG STRUCTURE; HUMAN; INTESTINE EPITHELIUM; INTESTINE MUCOSA PERMEABILITY; MEMBRANE DAMAGE; MUCOSA; NONHUMAN; PH; PRIORITY JOURNAL; PROTON TRANSPORT; REVIEW; TIGHT JUNCTION;

ADMINISTRATION, ORAL; ANIMALS; CHITIN; CHITOSAN; EXCIPIENTS; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; PHARMACEUTICAL PREPARATIONS;

EID: 0035813752     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(01)00231-9     Document Type: Review

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