Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: The effect of mucus on particle adsorption and transport

Pharmaceutical Research

Volumn 19, Issue 8, 2002, Pages 1185-1193

  Behrens, Isabel ^a   Vila Pena, Ana Isabel ^b   Alonso, Maria José ^b   Kissel, Thomas ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Caco 2; Endocytosis; Mucus; Nanoparticles; Oral vaccines; Peroral drug delivery

Indexed keywords

CHITOSAN; MACROGOL; NANOPARTICLE; POLYLACTIC ACID; POLYSTYRENE; PROTAMINE; PROTASAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG ADSORPTION; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; INTESTINE ABSORPTION; INTESTINE EPITHELIUM CELL; MONOLAYER CULTURE; MUCUS; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; TRANSCYTOSIS;

ADHESIVES; ADSORPTION; ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; HUMANS; INTESTINAL MUCOSA; MUCUS; NANOTECHNOLOGY; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036692366     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1019854327540     Document Type: Article

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