메뉴 건너뛰기




Volumn 13, Issue 12, 1996, Pages 1760-1764

Oral controlled release technology for peptides: Status and future prospects

Author keywords

Absorption enhancers; Chemical stability; Enzymatic degradation; Oral drug delivery; Peptide absorption

Indexed keywords

ACYLCARNITINE; CALCITONIN; CYCLOSPORIN; GLUCOSE; GLYCOCHOLATE SODIUM; INSULIN; PEPTIDES AND PROTEINS; PROTEINASE INHIBITOR; SALICYLATE SODIUM;

EID: 0030460690     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016008419367     Document Type: Review
Times cited : (131)

References (33)
  • 1
    • 0022917595 scopus 로고
    • Peptide and related drugs: A review of their absorption, metabolism, and excretion
    • M. J. Humphrey and P. S. Ringrose. Peptide and related drugs: A review of their absorption, metabolism, and excretion. Drug Metab. Reviews 17:283-310 (1986).
    • (1986) Drug Metab. Reviews , vol.17 , pp. 283-310
    • Humphrey, M.J.1    Ringrose, P.S.2
  • 2
    • 0026329336 scopus 로고
    • Mucosal penetration enhancers for facilitation of peptide and protein drug absorption
    • V. H. L. Lee, A. Yamamoto, and U. B. Kompella. Mucosal penetration enhancers for facilitation of peptide and protein drug absorption. Crit. Rev. Ther. Drug Carrier Systems 8:91-192 (1991).
    • (1991) Crit. Rev. Ther. Drug Carrier Systems , vol.8 , pp. 91-192
    • Lee, V.H.L.1    Yamamoto, A.2    Kompella, U.B.3
  • 3
    • 0028107970 scopus 로고
    • New aspects of pharmaceutical dosage forms for controlled drug delivery of peptides and proteins
    • H. P. Merkle. New aspects of pharmaceutical dosage forms for controlled drug delivery of peptides and proteins. Eur. J. Pharm. Sci. 2:19-21 (1994).
    • (1994) Eur. J. Pharm. Sci. , vol.2 , pp. 19-21
    • Merkle, H.P.1
  • 4
    • 0028609750 scopus 로고
    • Bioadhesion technologies for the delivery of peptide and protein drugs to the gastrointestinal tract
    • C. Lehr. Bioadhesion technologies for the delivery of peptide and protein drugs to the gastrointestinal tract. Crit. Rev. Ther. Drug Carrier Systems 11:119-160 (1994).
    • (1994) Crit. Rev. Ther. Drug Carrier Systems , vol.11 , pp. 119-160
    • Lehr, C.1
  • 5
    • 0029074505 scopus 로고
    • Using microemulsion formulations for oral drug delivery of therapeutic peptides
    • J. M. Sarciaux, L. Acar, and P. A. Sado. Using microemulsion formulations for oral drug delivery of therapeutic peptides. Int. J. Pharm. 120:127-136 (1995).
    • (1995) Int. J. Pharm. , vol.120 , pp. 127-136
    • Sarciaux, J.M.1    Acar, L.2    Sado, P.A.3
  • 6
    • 0002604431 scopus 로고
    • The oral bioavailability of peptides and related drugs
    • S. S. Davis, L. Illum, and E. Thomlinson (eds.), Plenum Press, New York
    • M. J. Humphrey. The oral bioavailability of peptides and related drugs. In S. S. Davis, L. Illum, and E. Thomlinson (eds.), Delivery Systems for Peptide Drugs, pp. 139-151, 1986, Plenum Press, New York.
    • (1986) Delivery Systems for Peptide Drugs , pp. 139-151
    • Humphrey, M.J.1
  • 7
    • 0023735020 scopus 로고
    • Enzymatic barriers to peptide and protein absorption
    • V. H. L. Lee. Enzymatic barriers to peptide and protein absorption. Crit. Rev. Ther. Drug Carrier Systems 5:69-97 (1988).
    • (1988) Crit. Rev. Ther. Drug Carrier Systems , vol.5 , pp. 69-97
    • Lee, V.H.L.1
  • 8
    • 0019969378 scopus 로고
    • Enhanced rectal bioavailability of polypeptides using sodium 5-methoxysalicylate as an absorption promoter
    • S. Yoshioka, L. Caldwell, and T. Higuchi. Enhanced rectal bioavailability of polypeptides using sodium 5-methoxysalicylate as an absorption promoter. J. Pharm. Sci. 71:593-597 (1982).
    • (1982) J. Pharm. Sci. , vol.71 , pp. 593-597
    • Yoshioka, S.1    Caldwell, L.2    Higuchi, T.3
  • 9
    • 0027942425 scopus 로고
    • Enhancement of intestinal insulin absorption by bile salt-fatty acid mixed micelles in dogs
    • J. C. Scott-Moncrieff, Z. Shao, and A. K. Mitra. Enhancement of intestinal insulin absorption by bile salt-fatty acid mixed micelles in dogs. J. Pharm. Sci. 83:1465-1469 (1994).
    • (1994) J. Pharm. Sci. , vol.83 , pp. 1465-1469
    • Scott-Moncrieff, J.C.1    Shao, Z.2    Mitra, A.K.3
  • 10
    • 0024523271 scopus 로고
    • Citric acid as an adjuvant for transepithelial transport
    • M. J. Cho, J. F. Scieszka, and P. S. Burton. Citric acid as an adjuvant for transepithelial transport. Int. J. Pharm. 52:79-81 (1989).
    • (1989) Int. J. Pharm. , vol.52 , pp. 79-81
    • Cho, M.J.1    Scieszka, J.F.2    Burton, P.S.3
  • 11
    • 0017372108 scopus 로고
    • Potential absorption of heparin from the small intestine and the large intestine in the presence of monoolein mixed micelles
    • S. Muranishi, Y. Tokunaga, K. Taniguchi, and H. Sezaki. Potential absorption of heparin from the small intestine and the large intestine in the presence of monoolein mixed micelles. Chem. Pharm. Bull. 25:1159-1163 (1977).
    • (1977) Chem. Pharm. Bull. , vol.25 , pp. 1159-1163
    • Muranishi, S.1    Tokunaga, Y.2    Taniguchi, K.3    Sezaki, H.4
  • 13
    • 0027398097 scopus 로고
    • Differential effects of anionic, cationic, nonionic, and physiologic surfactant on the dissociation, chymotrypsin degradation, and enterai absorption of insulin hexamers
    • Z. Shao, Y. Li, R. Krishnamoorthy, T. Chermak, and A. K. Mitra. Differential effects of anionic, cationic, nonionic, and physiologic surfactant on the dissociation, chymotrypsin degradation, and enterai absorption of insulin hexamers. Pharm. Res. 10:243-250 (1993).
    • (1993) Pharm. Res. , vol.10 , pp. 243-250
    • Shao, Z.1    Li, Y.2    Krishnamoorthy, R.3    Chermak, T.4    Mitra, A.K.5
  • 15
    • 0028925376 scopus 로고
    • Starch microspheres induce pulsatile delivery of drugs and peptides across the epithelial barrier by reversible separation of tight junctions
    • E. Bjork, U. Isaksson, P. Edman, and P. Artursson. Starch microspheres induce pulsatile delivery of drugs and peptides across the epithelial barrier by reversible separation of tight junctions. J. Drug Targeting 2:501-507 (1995).
    • (1995) J. Drug Targeting , vol.2 , pp. 501-507
    • Bjork, E.1    Isaksson, U.2    Edman, P.3    Artursson, P.4
  • 17
    • 0028924726 scopus 로고
    • Increased oral absorption enhancement of insulin by medium viscosity hydroxypropyl cellulose
    • M. Mesiha and M. Sidhom. Increased oral absorption enhancement of insulin by medium viscosity hydroxypropyl cellulose. Int. J. Pharm. 114:137-140 (1995).
    • (1995) Int. J. Pharm. , vol.114 , pp. 137-140
    • Mesiha, M.1    Sidhom, M.2
  • 18
    • 0029037438 scopus 로고
    • Effective intestinal absorption of insulin in diabetic rats using enteric coated capsules containing sodium salicylate
    • E. A. Hosny, N. M. Khan Ghilzai, and A. H. Al-Dhawalie. Effective intestinal absorption of insulin in diabetic rats using enteric coated capsules containing sodium salicylate. Drug Devel. Ind. Pharm. 21:1583-1589 (1995).
    • (1995) Drug Devel. Ind. Pharm. , vol.21 , pp. 1583-1589
    • Hosny, E.A.1    Khan Ghilzai, N.M.2    Al-Dhawalie, A.H.3
  • 19
    • 0029079659 scopus 로고
    • Enteral absorption of octreotide: Modulation of intestinal permeability by distinct carbohydrates
    • G. Fricker and J. Drewe. Enteral absorption of octreotide: Modulation of intestinal permeability by distinct carbohydrates. J. Pharmacol. Exp. Ther. 274:826-832 (1995).
    • (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 826-832
    • Fricker, G.1    Drewe, J.2
  • 20
    • 0026758261 scopus 로고
    • Degradation of insulin by trypsin and alpha-chymotrypsin
    • J. P. F. Bai and G. L. Amidon. Degradation of insulin by trypsin and alpha-chymotrypsin. Pharm. Res. 9:969-978 (1992).
    • (1992) Pharm. Res. , vol.9 , pp. 969-978
    • Bai, J.P.F.1    Amidon, G.L.2
  • 22
    • 0027988721 scopus 로고
    • Effects of various protease inhibitors on the intestinal absorption and degradation of insulin in rats
    • A. Yamamato, T. Taniguchi, K. Rikyuu, T. Tsuji, T. Fujita, M. Murakami, and J. Muranishi. Effects of various protease inhibitors on the intestinal absorption and degradation of insulin in rats. Pharm. Res. 11:1496-1500 (1994).
    • (1994) Pharm. Res. , vol.11 , pp. 1496-1500
    • Yamamato, A.1    Taniguchi, T.2    Rikyuu, K.3    Tsuji, T.4    Fujita, T.5    Murakami, M.6    Muranishi, J.7
  • 23
    • 0025113804 scopus 로고
    • Protease inhibitors and penetration enhancers as approaches to modify peptide absorption
    • V. H. L. Lee. Protease inhibitors and penetration enhancers as approaches to modify peptide absorption. J. Controlled Rel. 13:213-223 (1991).
    • (1991) J. Controlled Rel. , vol.13 , pp. 213-223
    • Lee, V.H.L.1
  • 24
    • 0021871421 scopus 로고
    • Promoting effect of the new chymotrypsin inhibitor FK-448 on the intestinal absorption of insulin in rats and dogs
    • S. Fuiji, T. Yokohama, K. Ikegaya, F. Sato, and N. Yohoo. Promoting effect of the new chymotrypsin inhibitor FK-448 on the intestinal absorption of insulin in rats and dogs. J. Pharm. Pharmacol. 37:545-549 (1985).
    • (1985) J. Pharm. Pharmacol. , vol.37 , pp. 545-549
    • Fuiji, S.1    Yokohama, T.2    Ikegaya, K.3    Sato, F.4    Yohoo, N.5
  • 25
    • 0029092672 scopus 로고
    • Nanoparticles as carriers for oral peptide absorption: Studies on particle uptake and fate
    • A. T. Florence, A. M. Hillery, N. Hussain, and P. U. Jani. Nanoparticles as carriers for oral peptide absorption: Studies on particle uptake and fate. J. Controlled Rel. 36:36-46 (1995).
    • (1995) J. Controlled Rel. , vol.36 , pp. 36-46
    • Florence, A.T.1    Hillery, A.M.2    Hussain, N.3    Jani, P.U.4
  • 27
    • 0028794951 scopus 로고
    • Colonic drug delivery of small peptides
    • S. Rao and W. A. Ritschel. Colonic drug delivery of small peptides. S.T.P. Pharma Sciences 5:19-29 (1995).
    • (1995) S.T.P. Pharma Sciences , vol.5 , pp. 19-29
    • Rao, S.1    Ritschel, W.A.2
  • 28
    • 0026574779 scopus 로고
    • Hydrogels for site-specific drug delivery to the colon: In vitro and in vivo degradation
    • H. Brondsted and J. Kopecek. Hydrogels for site-specific drug delivery to the colon: in vitro and in vivo degradation. Pharm. Res. 9:1540-1545 (1992).
    • (1992) Pharm. Res. , vol.9 , pp. 1540-1545
    • Brondsted, H.1    Kopecek, J.2
  • 29
    • 0027476168 scopus 로고
    • In vitro evaluation of calcium pectinate: A potential colonic-specific drug delivery carrier
    • A. Rubinstein, R. Radai, M. Ezra, S. Pathak, and J. S. Rokem. In vitro evaluation of calcium pectinate: a potential colonic-specific drug delivery carrier. Pharm. Res. 10:258-263 (1993).
    • (1993) Pharm. Res. , vol.10 , pp. 258-263
    • Rubinstein, A.1    Radai, R.2    Ezra, M.3    Pathak, S.4    Rokem, J.S.5
  • 30
    • 0029094147 scopus 로고
    • Transepithelial transport of insulin: I. Insulin degradation by insulin-degrading enzyme in small intestinal epithelium
    • J. P. F. Bai and L. L. Chang. Transepithelial transport of insulin: I. Insulin degradation by insulin-degrading enzyme in small intestinal epithelium. Pharm. Res. 12:1171-1175 (1995).
    • (1995) Pharm. Res. , vol.12 , pp. 1171-1175
    • Bai, J.P.F.1    Chang, L.L.2
  • 31
    • 0029075144 scopus 로고
    • Gastrointestinal absorption of peptide drug: Quantitative evaluation of the degradation and the permeation of metkephamid in rat small intestine
    • Y. Taki, T. Sakane, T. Nadai, H. Sezaki, G. L. Amidon, P. Langguth, and S. Yamashita. Gastrointestinal absorption of peptide drug: Quantitative evaluation of the degradation and the permeation of metkephamid in rat small intestine. J. Pharmacol. Exp. Ther. 274:373-377 (1995).
    • (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 373-377
    • Taki, Y.1    Sakane, T.2    Nadai, T.3    Sezaki, H.4    Amidon, G.L.5    Langguth, P.6    Yamashita, S.7
  • 32
    • 0000888475 scopus 로고
    • Oral route of peptide and protein drug delivery
    • V. H. L. Lee (ed.), Dekker, New York
    • V. H. L. Lee, S. Dodda-Kashi, G. M. Grass, and W. Rubas. Oral route of peptide and protein drug delivery. In V. H. L. Lee (ed.), Protein and Peptide Drug Delivery, pp. 691-738, 1991, Dekker, New York.
    • (1991) Protein and Peptide Drug Delivery , pp. 691-738
    • Lee, V.H.L.1    Dodda-Kashi, S.2    Grass, G.M.3    Rubas, W.4
  • 33
    • 0026599869 scopus 로고
    • Insulin stabilization and GI absorption
    • L. Hovgaard, E. J. Mack, and S. W. Kim. Insulin stabilization and GI absorption. J. Controlled Rel. 19:99-108 (1992).
    • (1992) J. Controlled Rel. , vol.19 , pp. 99-108
    • Hovgaard, L.1    Mack, E.J.2    Kim, S.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.