Opening of epithelial tight junctions and enhancement of paracellular permeation by chitosan: Microscopic, ultrastructural, and computed-tomographic observations

Molecular Pharmaceutics

Volumn 9, Issue 5, 2012, Pages 1271-1279

  Sonaje, Kiran ^a   Chuang, Er Yuan ^a   Lin, Kun Ju ^b,c   Yen, Tzu Chen ^c   Su, Fang Yi ^a   Tseng, Michael T ^d   Sung, Hsing Wen ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^d University of Louisville School of Medicine   (United States)

Author keywords

computed tomography; electron microscopy; intestinal absorption; paracellular permeability; protein delivery

Indexed keywords

CHITOSAN; INSULIN; JUNCTIONAL ADHESION MOLECULE A; LANTHANUM; NANOPARTICLE;

ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VIVO STUDY; INTRACELLULAR TRANSPORT; ISOTOPE LABELING; MICROVILLUS; PRIORITY JOURNAL; PROTEIN TRANSPORT; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY;

CACO-2 CELLS; CELL ADHESION MOLECULES; CHITOSAN; EPITHELIUM; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; RECEPTORS, CELL SURFACE; TIGHT JUNCTIONS;

EID: 84860726458     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200572t     Document Type: Article

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