The use of thiolated polymers as carrier matrix in oral peptide delivery - Proof of concept

Journal of Controlled Release

Volumn 106, Issue 1-2, 2005, Pages 26-33

  Bernkop Schnürch, Andreas ^a   Pinter, Yvonne ^a   Guggi, Davide ^a   Kahlbacher, Hermann ^b   Schöffmann, Gudrun ^b   Schuh, Maximilian ^b   Schmerold, Ivo ^b   Del Curto, Maria Dorly ^c   D'Antonio, Mauro ^c   Esposito, Pierandrea ^c   Huck, Christian ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^c Drug Delivery Systems   (Italy)

Author keywords

Antide; In vivo study; Oral peptide delivery; Peptidases; Thiolated polymers

Indexed keywords

ADHESION; COATING TECHNIQUES; DISSOLUTION; DRUG DOSAGE; POLYPEPTIDES;

ANTIDE; IN VIVO STUDY; ORAL PEPTIDE DELIVERY; PEPTIDASES; THIOLATED POLYMERS;

POLYMERS;

CHITOSAN 4 THIOBUTYLAMIDINE; CHYMOTRYPSIN; DRUG CARRIER; ELASTASE; GASTROINTESTINAL POLYPEPTIDE; GLUTATHIONE; ITURELIX; PEPSIN A; PEPTIDASE; POLYMER; TRYPSIN; UNCLASSIFIED DRUG; WATER;

ADHESION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DEMINERALIZATION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; ESOPHAGUS; MOUTH CAVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; SWINE; TABLET COMPRESSION; TABLET FORMULATION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CHITIN; CHYMOTRYPSIN; DRUG CARRIERS; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; OLIGOPEPTIDES; PANCREATIC ELASTASE; PEPSIN A; POLYMERS; SULFHYDRYL COMPOUNDS; SWINE; TRYPSIN;

EID: 23744465756     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.04.004     Document Type: Article

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