Oral delivery of insulin associated to polymeric nanoparticles in diabetic rats

Journal of Controlled Release

Volumn 117, Issue 2, 2007, Pages 163-170

  Damgé, Christiane ^a   Maincent, Philippe ^a   Ubrich, Nathalie ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

Author keywords

Insulin; Intestinal uptake; Nanoparticles; Oral delivery

Indexed keywords

ADHESIVES; BIODEGRADATION; DISEASES; ENCAPSULATION; NANOSTRUCTURED MATERIALS; POLYESTERS;

BIODEGRADABLE POLYESTERS; INTESTINAL UPTAKE; NANOPARTICLES; ORAL DELIVERY;

INSULIN;

DRUG CARRIER; EUDRAGIT RS; FLUORESCEIN ISOTHIOCYANATE; INSULIN; NANOPARTICLE; NEUTRAL INSULIN; POLYCAPROLACTONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DOSE COMPARISON; DRUG DOSE REDUCTION; DRUG UPTAKE; INSULIN BLOOD LEVEL; INSULIN CLEARANCE; INTESTINE ABSORPTION; INTESTINE MUCOSA; MALE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROVOCATION TEST; RAT;

ACRYLIC RESINS; ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE TOLERANCE TEST; INJECTIONS, SUBCUTANEOUS; INSULIN; INTESTINAL MUCOSA; MALE; NANOCAPSULES; PARTICLE SIZE; PEYER'S PATCHES; POLYESTERS; POLYMERS; RATS; RATS, WISTAR;

EID: 33846543799     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.10.023     Document Type: Article

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