Nanoparticles of quaternized chitosan derivatives as a carrier for colon delivery of insulin: Ex vivo and in vivo studies

International Journal of Pharmaceutics

Volumn 356, Issue 1-2, 2008, Pages 259-266

  Bayat, Akbar ^a,b   Dorkoosh, Farid A ^a   Dehpour, Ahmad Reza ^c   Moezi, Leila ^c   Larijani, Bagher ^d   Junginger, Hans E ^e,f   Rafiee Tehrani, Morteza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Cosar Pharmaceutical Company ^*  (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e LEIDEN UNIVERSITY   (Netherlands)

^f NARESUAN UNIVERSITY   (Thailand)

Author keywords

Chitosan; Dimethylethyl chitosan; Ex vivo and in vivo studies; Insulin; Nanoparticles; Triethyl chitosan

Indexed keywords

CHITOSAN DERIVATIVE; DIMETHYLETHYLCHITOSAN; INSULIN; NANOPARTICLE; POLYELECTROLYTE; TRIETHYLCHITOSAN;

ANIMAL EXPERIMENT; ARTICLE; COLON; COMPLEX FORMATION; CONTROLLED STUDY; DRUG ABSORPTION; EX VIVO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MALE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ANIMALS; CHITOSAN; COLON; DELAYED-ACTION PREPARATIONS; DIABETES MELLITUS, EXPERIMENTAL; DRUG DELIVERY SYSTEMS; ELECTROLYTES; HYPOGLYCEMIC AGENTS; INSULIN; LIGHT; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; RATS; RATS, WISTAR; SCATTERING, RADIATION;

EID: 42649142580     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.12.037     Document Type: Article

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