Enhancement of paracellular drug transport with highly quaternized N- trimethyl chitosan chloride in neutral environments: In vitro evaluation in intestinal epithelial cells (Caco-2)

Journal of Pharmaceutical Sciences

Volumn 88, Issue 2, 1999, Pages 253-257

  Kotzé, Awie F ^a,b   Thanou, Maya M ^b   Lueben, Henrik L ^b,c   De Boer, A G ^b   Verhoef, J Coos ^b   Junginger, Hans E ^b  

^a NORTH WEST UNIVERSITY   (South Africa)

^b LEIDEN UNIVERSITY   (Netherlands)

^c LTS Lohmann Therapie Systeme AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN; MANNITOL; POLYMER; TRYPAN BLUE;

ARTICLE; CELL MEMBRANE PERMEABILITY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; HYDROPHILICITY; INTESTINE EPITHELIUM CELL; PH;

EID: 0033007333     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js980233c     Document Type: Article

References (18)

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