Unnatural amino acids as probes of ligand-receptor interactions and their conformational consequences

Annual Review of Pharmacology and Toxicology

Volumn 53, Issue , 2013, Pages 211-229

  Pless, Stephan A ^a   Ahern, Christopher A ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Cys loop receptors; G protein coupled receptors; nonsense suppression; pentameric ligand gated ion channels; voltage gated ion channels

Indexed keywords

AMINO ACID DERIVATIVE; G PROTEIN COUPLED RECEPTOR; ION CHANNEL; LIGAND; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; UNNATURAL AMINO ACID DERIVATIVE;

ANIMAL CELL; ATOM; BINDING SITE; HYDROGEN BOND; LIGAND BINDING; MOLECULAR INTERACTION; MUTATION; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN CONFORMATION; REVIEW; SUBSTITUTION REACTION; XENOPUS LAEVIS;

AMINO ACIDS; ANIMALS; BINDING SITES; HUMANS; ION CHANNELS; LIGANDS; MEMBRANE PROTEINS; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84872223512     PISSN: 03621642     EISSN: 15454304     Source Type: Book Series    
DOI: 10.1146/annurev-pharmtox-011112-140343     Document Type: Review

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