Photolabeling identifies transmembrane domain 4 of CXCR4 as a T140 binding site

Biochemical Pharmacology

Volumn 78, Issue 11, 2009, Pages 1382-1390

  Boulais, Philip E ^a   Dulude, Dominic ^b,c   Cabana, Jérôme ^a   Heveker, Nikolaus ^b,c   Escher, Emanuel ^a   Lavigne, Pierre ^a   Leduc, Richard ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITY OF MONTREAL   (Canada)

Author keywords

CXCR4; GPCR; Ligand binding pocket; Molecular modeling; Photoaffinity labeling; T140

Indexed keywords

AMINO ACID P BENZOYL PHENYLALANINE; CHEMOKINE RECEPTOR CXCR4; GLUTAMINE; LYSINE; PHENYLALANINE DERIVATIVE; T 140; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIGAND BINDING; MOLECULAR MODEL; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SYNTHESIS; WILD TYPE;

EID: 70349758088     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.07.007     Document Type: Article

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