-
1
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc K., et al. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature. 411:2001;269-276
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
-
2
-
-
0035113738
-
The tethered agonist approach to mapping ion channel proteins - Toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor
-
Li L., et al. The tethered agonist approach to mapping ion channel proteins - toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor. Chem. Biol. 8:2001;47-58
-
(2001)
Chem. Biol.
, vol.8
, pp. 47-58
-
-
Li, L.1
-
3
-
-
0037072311
-
3A) and nicotinic acetylcholine receptors: The anomalous binding properties of nicotine
-
3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine. Biochemistry. 41:2002;10262-10269
-
(2002)
Biochemistry
, vol.41
, pp. 10262-10269
-
-
Beene, D.L.1
-
4
-
-
0038277048
-
Different binding orientations for the same agonist at homologous receptors: A lock and key or a simple wedge?
-
Mu T.W., et al. Different binding orientations for the same agonist at homologous receptors: a lock and key or a simple wedge? J. Am. Chem. Soc. 125:2003;6850-6851
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 6850-6851
-
-
Mu, T.W.1
-
5
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
Miyazawa A., et al. Structure and gating mechanism of the acetylcholine receptor pore. Nature. 424:2003;949-955
-
(2003)
Nature
, vol.424
, pp. 949-955
-
-
Miyazawa, A.1
-
6
-
-
0035902019
-
Neurobiology. Snails, synapses and smokers
-
Dougherty, D.A. and Lester, H.A. (2001) Neurobiology. Snails, synapses and smokers. Nature 411, 252-253, 255.
-
(2001)
Nature
, vol.411
, pp. 252-253
-
-
Dougherty, D.A.1
Lester, H.A.2
-
7
-
-
0036891560
-
The nicotinic receptor ligand binding domain
-
Sine S.M. The nicotinic receptor ligand binding domain. J. Neurobiol. 53:2002;431-446
-
(2002)
J. Neurobiol.
, vol.53
, pp. 431-446
-
-
Sine, S.M.1
-
10
-
-
17944368301
-
The binding site of acetylcholine receptor as visualized in the X-ray structure of a complex between α-bungarotoxin and a mimotope peptide
-
Harel M., et al. The binding site of acetylcholine receptor as visualized in the X-ray structure of a complex between α-bungarotoxin and a mimotope peptide. Neuron. 32:2001;265-275
-
(2001)
Neuron
, vol.32
, pp. 265-275
-
-
Harel, M.1
-
11
-
-
0027208097
-
Negatively charged amino acid residues in the nicotinic receptor δ subunit that contribute to the binding of acetylcholine
-
Czajkowski C., et al. Negatively charged amino acid residues in the nicotinic receptor δ subunit that contribute to the binding of acetylcholine. Proc. Natl. Acad. Sci. U. S. A. 90:1993;6285-6289
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 6285-6289
-
-
Czajkowski, C.1
-
12
-
-
0029078817
-
Identification of a new component of the agonist binding site of the nicotinic α7 homooligomeric receptor
-
Corringer P.J., et al. Identification of a new component of the agonist binding site of the nicotinic α7 homooligomeric receptor. J. Biol. Chem. 270:1995;11749-11752
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11749-11752
-
-
Corringer, P.J.1
-
13
-
-
0037047296
-
Lysine scanning mutagenesis delineates structural model of the nicotinic receptor ligand binding domain
-
Sine S.M., et al. Lysine scanning mutagenesis delineates structural model of the nicotinic receptor ligand binding domain. J. Biol. Chem. 277:2002;29210-29223
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29210-29223
-
-
Sine, S.M.1
-
14
-
-
0037448581
-
A receptor
-
A receptor. Nature. 421:2003;272-275
-
(2003)
Nature
, vol.421
, pp. 272-275
-
-
Kash, T.L.1
-
15
-
-
0037457902
-
Identification of amino acids in the nicotinic acetylcholine receptor agonist binding site and ion channel photolabeled by 4-[(3-trifluoromethyl)-3H- diazirin-3-yl]benzoylcholine, a novel photoaffinity antagonist
-
Chiara D.C., et al. Identification of amino acids in the nicotinic acetylcholine receptor agonist binding site and ion channel photolabeled by 4-[(3-trifluoromethyl)-3H-diazirin-3-yl]benzoylcholine, a novel photoaffinity antagonist. Biochemistry. 42:2003;271-283
-
(2003)
Biochemistry
, vol.42
, pp. 271-283
-
-
Chiara, D.C.1
-
16
-
-
0347298753
-
3H]Ro15-4513
-
3H]Ro15-4513. J. Biol. Chem. 277:2002;50036-50045
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 50036-50045
-
-
Sawyer, G.W.1
-
17
-
-
0037023750
-
NMR structural analysis of α-bungarotoxin and its complex with the principal α-neurotoxin-binding sequence on the α7 subunit of a neuronal nicotinic acetylcholine receptor
-
Moise L., et al. NMR structural analysis of α-bungarotoxin and its complex with the principal α-neurotoxin-binding sequence on the α7 subunit of a neuronal nicotinic acetylcholine receptor. J. Biol. Chem. 277:2002;12406-12417
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12406-12417
-
-
Moise, L.1
-
18
-
-
0041352143
-
Acetylcholine binding protein (AChBP): A secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels
-
Sixma T.K., Smit A.B. Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels. Annu. Rev. Biophys. Biomol. Struct. 32:2003;311-334
-
(2003)
Annu. Rev. Biophys. Biomol. Struct.
, vol.32
, pp. 311-334
-
-
Sixma, T.K.1
Smit, A.B.2
-
19
-
-
0019959498
-
Functional stoichiometry at the nicotinic receptor. The photon cross-section for phase 1 corresponds to two Bis-Q molecules per channel
-
Sheridan R.E., Lester H.A. Functional stoichiometry at the nicotinic receptor. The photon cross-section for phase 1 corresponds to two Bis-Q molecules per channel. J. Gen. Physiol. 80:1982;499-515
-
(1982)
J. Gen. Physiol.
, vol.80
, pp. 499-515
-
-
Sheridan, R.E.1
Lester, H.A.2
-
21
-
-
0028921479
-
Acetylcholine receptor channel imaged in the open state
-
Unwin N. Acetylcholine receptor channel imaged in the open state. Nature. 373:1995;37-43
-
(1995)
Nature
, vol.373
, pp. 37-43
-
-
Unwin, N.1
-
22
-
-
0036304564
-
Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the α subunits
-
Unwin N., et al. Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the α subunits. J. Mol. Biol. 319:2002;1165-1176
-
(2002)
J. Mol. Biol.
, vol.319
, pp. 1165-1176
-
-
Unwin, N.1
-
23
-
-
0035141668
-
Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation
-
Wagner D.A., Czajkowski C. Structure and dynamics of the GABA binding pocket: a narrowing cleft that constricts during activation. J. Neurosci. 21:2001;67-74
-
(2001)
J. Neurosci.
, vol.21
, pp. 67-74
-
-
Wagner, D.A.1
Czajkowski, C.2
-
24
-
-
0032514762
-
From ab initio quantum mechanics to molecular neurobiology: A cation-π binding site in the nicotinic receptor
-
Zhong W., et al. From ab initio quantum mechanics to molecular neurobiology: a cation-π binding site in the nicotinic receptor. Proc. Natl. Acad. Sci. U. S. A. 95:1998;12088-12093
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 12088-12093
-
-
Zhong, W.1
-
25
-
-
0014685169
-
Acetylcholine receptor: Covalent attachment of depolarizing groups at the active site
-
Silman I., Karlin A. Acetylcholine receptor: covalent attachment of depolarizing groups at the active site. Science. 164:1969;1420-1421
-
(1969)
Science
, vol.164
, pp. 1420-1421
-
-
Silman, I.1
Karlin, A.2
-
26
-
-
0015103977
-
Photochromic activators of the acetylcholine receptor
-
Bartels E., et al. Photochromic activators of the acetylcholine receptor. Proc. Natl. Acad. Sci. U. S. A. 68:1971;1820-1823
-
(1971)
Proc. Natl. Acad. Sci. U. S. A.
, vol.68
, pp. 1820-1823
-
-
Bartels, E.1
-
27
-
-
0022924218
-
Activation of acetylcholine receptor channels by covalently bound agonists in cultured rat myoballs
-
Chabala L.D., Lester H.A. Activation of acetylcholine receptor channels by covalently bound agonists in cultured rat myoballs. J. Physiol. 379:1986;83-108
-
(1986)
J. Physiol.
, vol.379
, pp. 83-108
-
-
Chabala, L.D.1
Lester, H.A.2
-
28
-
-
0034724709
-
Mapping the agonist binding site of the nicotinic acetylcholine receptor. Orientation requirements for activation by covalent agonist
-
Sullivan D.A., Cohen J.B. Mapping the agonist binding site of the nicotinic acetylcholine receptor. Orientation requirements for activation by covalent agonist. J. Biol. Chem. 275:2000;12651-12660
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12651-12660
-
-
Sullivan, D.A.1
Cohen, J.B.2
-
29
-
-
0037202217
-
a at the binding site of the nicotinic acetylcholine receptor: Implications for nicotine binding
-
a at the binding site of the nicotinic acetylcholine receptor: implications for nicotine binding. J. Am. Chem. Soc. 124:2002;12662-12663
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 12662-12663
-
-
Petersson, E.J.1
-
30
-
-
1842475289
-
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
-
Celie P.H.N., et al. Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures. Neuron. 41:2004;907-914
-
(2004)
Neuron
, vol.41
, pp. 907-914
-
-
Celie, P.H.N.1
-
31
-
-
0002315013
-
Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine
-
Schapira M., et al. Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine. BMC Struct. Biol. 2:2002;1
-
(2002)
BMC Struct. Biol.
, vol.2
, pp. 1
-
-
Schapira, M.1
-
32
-
-
0037381989
-
3 receptor agonist-binding residues using homology modeling
-
3 receptor agonist-binding residues using homology modeling. Biophys. J. 84:2003;2338-2344
-
(2003)
Biophys. J.
, vol.84
, pp. 2338-2344
-
-
Reeves, D.C.1
-
33
-
-
0033534674
-
Backbone mutations in transmembrane domains of a ligand-gated ion channel: Implications for the mechanism of gating
-
England P.M., et al. Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating. Cell. 96:1999;89-98
-
(1999)
Cell
, vol.96
, pp. 89-98
-
-
England, P.M.1
-
34
-
-
0034046304
-
3 receptor gating
-
3 receptor gating. Mol. Pharmacol. 57:2000;1114-1122
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 1114-1122
-
-
Dang, H.1
-
35
-
-
0037044793
-
A receptor M2-M3 loop secondary structure and changes in accessibility during channel gating
-
A receptor M2-M3 loop secondary structure and changes in accessibility during channel gating. J. Biol. Chem. 277:2002;43002-43010
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43002-43010
-
-
Bera, A.K.1
-
36
-
-
0032568547
-
Mutations of γ-aminobutyric acid and glycine receptors change alcohol cutoff: Evidence for an alcohol receptor?
-
Wick M.J., et al. Mutations of γ-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? Proc. Natl. Acad. Sci. U. S. A. 95:1998;6504-6509
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6504-6509
-
-
Wick, M.J.1
-
37
-
-
0029593370
-
Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins
-
Karlin A., Akabas M.H. Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins. Neuron. 15:1995;1231-1244
-
(1995)
Neuron
, vol.15
, pp. 1231-1244
-
-
Karlin, A.1
Akabas, M.H.2
-
38
-
-
0032102496
-
The location of the gate in the acetylcholine receptor channel
-
Wilson G.G., Karlin A. The location of the gate in the acetylcholine receptor channel. Neuron. 20:1998;1269-1281
-
(1998)
Neuron
, vol.20
, pp. 1269-1281
-
-
Wilson, G.G.1
Karlin, A.2
-
39
-
-
0036480194
-
Emerging structure of the nicotinic acetylcholine receptors
-
Karlin A. Emerging structure of the nicotinic acetylcholine receptors. Nat. Rev. Neurosci. 3:2002;102-114
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 102-114
-
-
Karlin, A.1
-
40
-
-
0026485739
-
Acetylcholine receptor channel structure probed in cysteine-substitution mutants
-
Akabas M.H., et al. Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science. 258:1992;307-310
-
(1992)
Science
, vol.258
, pp. 307-310
-
-
Akabas, M.H.1
-
41
-
-
0035042719
-
A receptor pore-lining M2 segment
-
A receptor pore-lining M2 segment. Nat. Neurosci. 4:2001;477-485
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 477-485
-
-
Horenstein, J.1
-
42
-
-
0242268392
-
Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: Electrophysiology-coordinated photochemistry and mass spectrometry
-
Leite J.F., et al. Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: electrophysiology-coordinated photochemistry and mass spectrometry. Proc. Natl. Acad. Sci. U. S. A. 100:2003;13054-13059
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 13054-13059
-
-
Leite, J.F.1
-
43
-
-
0031027684
-
Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel
-
Lynch J.W., et al. Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel. EMBO J. 16:1997;110-120
-
(1997)
EMBO J.
, vol.16
, pp. 110-120
-
-
Lynch, J.W.1
-
44
-
-
0032520102
-
Properties of human glycine receptors containing the hyperekplexia mutation α1K276E, expressed in Xenopus oocytes
-
Lewis T.M., et al. Properties of human glycine receptors containing the hyperekplexia mutation α1K276E, expressed in Xenopus oocytes. J. Physiol. 507:1998;25-40
-
(1998)
J. Physiol.
, vol.507
, pp. 25-40
-
-
Lewis, T.M.1
-
45
-
-
0038493551
-
Asymmetric contribution of α and β subunits to the activation of αβ heteromeric glycine receptors
-
Shan Q., et al. Asymmetric contribution of α and β subunits to the activation of αβ heteromeric glycine receptors. J. Neurochem. 86:2003;498-507
-
(2003)
J. Neurochem.
, vol.86
, pp. 498-507
-
-
Shan, Q.1
-
46
-
-
0033253510
-
Gating of α3β4 neuronal nicotinic receptor can be controlled by the loop M2-M3 of both alpha3 and beta4 subunits
-
Rovira J.C., et al. Gating of α3β4 neuronal nicotinic receptor can be controlled by the loop M2-M3 of both alpha3 and beta4 subunits. Pflugers Arch. 439:1999;86-92
-
(1999)
Pflugers Arch.
, vol.439
, pp. 86-92
-
-
Rovira, J.C.1
-
47
-
-
0031864943
-
A residue in the middle of the M2-M3 loop of the β4 subunit specifically affects gating of neuronal nicotinic receptors
-
Rovira J.C., et al. A residue in the middle of the M2-M3 loop of the β4 subunit specifically affects gating of neuronal nicotinic receptors. FEBS Lett. 433:1998;89-92
-
(1998)
FEBS Lett.
, vol.433
, pp. 89-92
-
-
Rovira, J.C.1
-
48
-
-
0029954238
-
A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors
-
Campos-Caro A., et al. A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors. Proc. Natl. Acad. Sci. U. S. A. 93:1996;6118-6123
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 6118-6123
-
-
Campos-Caro, A.1
-
49
-
-
0035851193
-
The role and predicted propensity of conserved proline residues in the 5-HT3 receptor
-
Deane C.M., Lummis S.C. The role and predicted propensity of conserved proline residues in the 5-HT3 receptor. J. Biol. Chem. 276:2001;37962-37966
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37962-37966
-
-
Deane, C.M.1
Lummis, S.C.2
-
50
-
-
0032841745
-
A receptor
-
A receptor. J. Neurochem. 73:1999;1758-1764
-
(1999)
J. Neurochem.
, vol.73
, pp. 1758-1764
-
-
Sigel, E.1
-
51
-
-
0028177448
-
Mutagenesis of the GABA ρ1 receptor alters agonist affinity and channel gating
-
Kusama T., et al. Mutagenesis of the GABA ρ1 receptor alters agonist affinity and channel gating. NeuroReport. 5:1994;1209-1212
-
(1994)
NeuroReport
, vol.5
, pp. 1209-1212
-
-
Kusama, T.1
-
52
-
-
0034785541
-
A receptor α1 subunit reveals a domain that affects sensitivity to GABA and benzodiazepine-site ligands
-
A receptor α1 subunit reveals a domain that affects sensitivity to GABA and benzodiazepine-site ligands. J. Neurochem. 79:2001;55-62
-
(2001)
J. Neurochem.
, vol.79
, pp. 55-62
-
-
Davies, M.1
-
53
-
-
0034725597
-
Arg-274 and Leu-277 of the γ-aminobutyric acid type a receptor α2 subunit define agonist efficacy and potency
-
O'Shea S.M., Harrison N.L. Arg-274 and Leu-277 of the γ-aminobutyric acid type A receptor α2 subunit define agonist efficacy and potency. J. Biol. Chem. 275:2000;22764-22768
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 22764-22768
-
-
O'Shea, S.M.1
Harrison, N.L.2
-
54
-
-
0035871765
-
The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state
-
Lynch J.W., et al. The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state. J. Neurosci. 21:2001;2589-2599
-
(2001)
J. Neurosci.
, vol.21
, pp. 2589-2599
-
-
Lynch, J.W.1
-
55
-
-
0030987817
-
Mutations in different functional domains of the human muscle acetylcholine receptor α subunit in patients with the slow-channel congenital myasthenic syndrome
-
Croxen R., et al. Mutations in different functional domains of the human muscle acetylcholine receptor α subunit in patients with the slow-channel congenital myasthenic syndrome. Hum. Mol. Genet. 6:1997;767-774
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 767-774
-
-
Croxen, R.1
-
56
-
-
0033811476
-
The extracellular linker of muscle acetylcholine receptor channels is a gating control element
-
Grosman C., et al. The extracellular linker of muscle acetylcholine receptor channels is a gating control element. J. Gen. Physiol. 116:2000;327-340
-
(2000)
J. Gen. Physiol.
, vol.116
, pp. 327-340
-
-
Grosman, C.1
-
57
-
-
0342375947
-
Membrane-buried proline residue is a key element in the gating of α7 nicotinic receptor
-
Dang H., et al. Membrane-buried proline residue is a key element in the gating of α7 nicotinic receptor. Soc. Neurosci. Abstr. 21:1995;343
-
(1995)
Soc. Neurosci. Abstr.
, vol.21
, pp. 343
-
-
Dang, H.1
-
58
-
-
0030923523
-
Site-specific, photochemical proteolysis applied to ion channels in vivo
-
England P.M., et al. Site-specific, photochemical proteolysis applied to ion channels in vivo. Proc. Natl. Acad. Sci. U. S. A. 94:1997;11025-11030
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 11025-11030
-
-
England, P.M.1
-
59
-
-
0042355340
-
Agonist-induced conformational changes in the extracellular domain of α7 nicotinic acetylcholine receptors
-
Lyford L.K., et al. Agonist-induced conformational changes in the extracellular domain of α7 nicotinic acetylcholine receptors. Mol. Pharmacol. 64:2003;650-658
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 650-658
-
-
Lyford, L.K.1
-
60
-
-
0028809730
-
Identification of acetylcholine receptor channel-lining residues in the M1 segment of the β-subunit
-
Akabas M.H., Karlin A. Identification of acetylcholine receptor channel-lining residues in the M1 segment of the β-subunit. Biochemistry. 34:1995;12496-12500
-
(1995)
Biochemistry
, vol.34
, pp. 12496-12500
-
-
Akabas, M.H.1
Karlin, A.2
-
61
-
-
0031456382
-
Identification of acetylcholine receptor channel-lining residues in the M1 segment of the β-subunit
-
Zhang H., Karlin A. Identification of acetylcholine receptor channel-lining residues in the M1 segment of the β-subunit. Biochemistry. 36:1997;15856-15864
-
(1997)
Biochemistry
, vol.36
, pp. 15856-15864
-
-
Zhang, H.1
Karlin, A.2
-
62
-
-
0034677524
-
Mapping the conformational wave of acetylcholine receptor channel gating
-
Grosman C., et al. Mapping the conformational wave of acetylcholine receptor channel gating. Nature. 403:2000;773-776
-
(2000)
Nature
, vol.403
, pp. 773-776
-
-
Grosman, C.1
-
63
-
-
0037197654
-
Structure of the transition state of gating in the acetylcholine receptor channel pore: A Φ-value analysis
-
Cymes G.D., et al. Structure of the transition state of gating in the acetylcholine receptor channel pore: a Φ-value analysis. Biochemistry. 41:2002;5548-5555
-
(2002)
Biochemistry
, vol.41
, pp. 5548-5555
-
-
Cymes, G.D.1
-
64
-
-
24444477410
-
A fluorophore attached to nicotinic acetylcholine receptor βM2 detects agonist binding to the αδ site
-
(in press).
-
Dahan, D., et al. A fluorophore attached to nicotinic acetylcholine receptor βM2 detects agonist binding to the αδ site. Proc. Natl. Acad. Sci. U. S. A. (in press).
-
Proc. Natl. Acad. Sci. U. S. A.
-
-
Dahan, D.1
-
65
-
-
3543062342
-
Ligand-gated ion channels: Mechanisms underlying ion selectivity
-
(in press).
-
Keramidas, A., et al. Ligand-gated ion channels: mechanisms underlying ion selectivity. Prog. Biophys. Mol. Biol. (in press).
-
Prog. Biophys. Mol. Biol.
-
-
Keramidas, A.1
-
66
-
-
0032967642
-
Nicotinic acetylcholine receptor at 4.6 Å resolution: Transverse tunnels in the channel wall
-
Miyazawa A., et al. Nicotinic acetylcholine receptor at 4.6 Å resolution: transverse tunnels in the channel wall. J. Mol. Biol. 288:1999;765-786
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 765-786
-
-
Miyazawa, A.1
-
67
-
-
0010214174
-
Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor
-
Finer-Moore J., Stroud R.M. Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor. Proc. Natl. Acad. Sci. U. S. A. 81:1984;155-159
-
(1984)
Proc. Natl. Acad. Sci. U. S. A.
, vol.81
, pp. 155-159
-
-
Finer-Moore, J.1
Stroud, R.M.2
-
68
-
-
0041806486
-
3 receptors
-
3 receptors. Nature. 424:2003;321-324
-
(2003)
Nature
, vol.424
, pp. 321-324
-
-
Kelley, S.P.1
-
69
-
-
0028084921
-
ATP-activated current and its interaction with acetylcholine-activated current in rat sympathetic neurons
-
Nakazawa K. ATP-activated current and its interaction with acetylcholine-activated current in rat sympathetic neurons. J. Neurosci. 14:1994;740-750
-
(1994)
J. Neurosci.
, vol.14
, pp. 740-750
-
-
Nakazawa, K.1
-
70
-
-
0032143071
-
Mutual occlusion of P2X ATP receptors and nicotinic receptors on sympathetic neurons of the guinea-pig
-
Searl T.J., et al. Mutual occlusion of P2X ATP receptors and nicotinic receptors on sympathetic neurons of the guinea-pig. J. Physiol. 510:1998;783-791
-
(1998)
J. Physiol.
, vol.510
, pp. 783-791
-
-
Searl, T.J.1
-
71
-
-
0032535034
-
Non-additive interaction between nicotinic cholinergic and P2X purine receptors in guinea-pig enteric neurons in culture
-
Zhou X., Galligan J.J. Non-additive interaction between nicotinic cholinergic and P2X purine receptors in guinea-pig enteric neurons in culture. J. Physiol. 513:1998;685-697
-
(1998)
J. Physiol.
, vol.513
, pp. 685-697
-
-
Zhou, X.1
Galligan, J.J.2
-
72
-
-
0032535426
-
Functional interactions between nicotinic and P2X channels in short-term cultures of guinea-pig submucosal neurons
-
Barajas-Lopez C., et al. Functional interactions between nicotinic and P2X channels in short-term cultures of guinea-pig submucosal neurons. J. Physiol. 513:1998;671-683
-
(1998)
J. Physiol.
, vol.513
, pp. 671-683
-
-
Barajas-Lopez, C.1
-
73
-
-
0034721119
-
State-dependent cross-inhibition between transmitter-gated cation channels
-
Khakh B.S., et al. State-dependent cross-inhibition between transmitter-gated cation channels. Nature. 406:2000;405-410
-
(2000)
Nature
, vol.406
, pp. 405-410
-
-
Khakh, B.S.1
-
74
-
-
0033366463
-
Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds
-
Khakh B.S., et al. Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds. Nat. Neurosci. 2:1999;322-330
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 322-330
-
-
Khakh, B.S.1
-
75
-
-
0033360313
-
Pore dilation of neuronal P2X receptor channels
-
Virginio C., et al. Pore dilation of neuronal P2X receptor channels. Nat. Neurosci. 2:1999;315-321
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 315-321
-
-
Virginio, C.1
-
76
-
-
0037443123
-
Intracellular cross talk and physical interaction between two classes of neurotransmitter-gated channels
-
Boue-Grabot E., et al. Intracellular cross talk and physical interaction between two classes of neurotransmitter-gated channels. J. Neurosci. 23:2003;1246-1253
-
(2003)
J. Neurosci.
, vol.23
, pp. 1246-1253
-
-
Boue-Grabot, E.1
-
77
-
-
0344443178
-
Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda
-
Chimienti F., et al. Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda. Hum. Mol. Genet. 12:2003;3017-3024
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 3017-3024
-
-
Chimienti, F.1
-
78
-
-
0037075542
-
Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1
-
Ibanez-Tallon I., et al. Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1. Neuron. 33:2002;893-903
-
(2002)
Neuron
, vol.33
, pp. 893-903
-
-
Ibanez-Tallon, I.1
-
79
-
-
0033136270
-
Lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS
-
Miwa J.M., et al. lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron. 23:1999;105-114
-
(1999)
Neuron
, vol.23
, pp. 105-114
-
-
Miwa, J.M.1
-
80
-
-
0033136331
-
α neurotoxins and their relatives: Foes and friends?
-
Hall Z.W. α neurotoxins and their relatives: foes and friends? Neuron. 23:1999;4-5
-
(1999)
Neuron
, vol.23
, pp. 4-5
-
-
Hall, Z.W.1
-
81
-
-
0242583056
-
The role of loop 5 in acetylcholine receptor channel gating
-
Chakrapani S., et al. The role of loop 5 in acetylcholine receptor channel gating. J. Gen. Physiol. 122:2003;521-539
-
(2003)
J. Gen. Physiol.
, vol.122
, pp. 521-539
-
-
Chakrapani, S.1
-
82
-
-
0242353157
-
EXP-1 is an excitatory GABA-gated cation channel
-
Beg A.A., Jorgensen E.M. EXP-1 is an excitatory GABA-gated cation channel. Nat. Neurosci. 6:2003;1145-1152
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 1145-1152
-
-
Beg, A.A.1
Jorgensen, E.M.2
-
84
-
-
10744232323
-
Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors
-
Samochocki M., et al. Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. J. Pharmacol. Exp. Ther. 305:2003;1024-1036
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 1024-1036
-
-
Samochocki, M.1
-
85
-
-
15144343497
-
Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors
-
Bannon A.W., et al. Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors. Science. 279:1998;77-81
-
(1998)
Science
, vol.279
, pp. 77-81
-
-
Bannon, A.W.1
-
86
-
-
0037176809
-
Smoking and Parkinson's disease in twins
-
Tanner C.M., et al. Smoking and Parkinson's disease in twins. Neurology. 58:2002;581-588
-
(2002)
Neurology
, vol.58
, pp. 581-588
-
-
Tanner, C.M.1
-
87
-
-
0031766318
-
Transdermal nicotine effects on attention
-
Levin E.D., et al. Transdermal nicotine effects on attention. Psychopharmacology. 140:1998;135-141
-
(1998)
Psychopharmacology
, vol.140
, pp. 135-141
-
-
Levin, E.D.1
-
88
-
-
0036632416
-
A pilot controlled trial of transdermal nicotine in the treatment of attention deficit hyperactivity disorder
-
Shytle R.D., et al. A pilot controlled trial of transdermal nicotine in the treatment of attention deficit hyperactivity disorder. World J. Biol. Psychiatry. 3:2002;150-155
-
(2002)
World J. Biol. Psychiatry
, vol.3
, pp. 150-155
-
-
Shytle, R.D.1
-
89
-
-
0030749161
-
The effect of mesalamine and nicotine in the treatment of inflammatory bowel disease
-
Bonapace C.R., Mays D.A. The effect of mesalamine and nicotine in the treatment of inflammatory bowel disease. Ann. Pharmacother. 31:1997;907-913
-
(1997)
Ann. Pharmacother.
, vol.31
, pp. 907-913
-
-
Bonapace, C.R.1
Mays, D.A.2
-
90
-
-
0041914565
-
Nicotine as an antiepileptic agent in ADNFLE: An N-of-one study
-
Willoughby J.O., et al. Nicotine as an antiepileptic agent in ADNFLE: an N-of-one study. Epilepsia. 44:2003;1238-1240
-
(2003)
Epilepsia
, vol.44
, pp. 1238-1240
-
-
Willoughby, J.O.1
-
91
-
-
0030439041
-
RJR-2403: A nicotinic agonist with CNS selectivity II. In vivo characterization
-
Lippiello P.M., et al. RJR-2403: a nicotinic agonist with CNS selectivity II. In vivo characterization. J. Pharmacol. Exp. Ther. 279:1996;1422-1429
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.279
, pp. 1422-1429
-
-
Lippiello, P.M.1
-
92
-
-
0037224654
-
A receptor mutation
-
A receptor mutation. Brain. 126:2003;230-240
-
(2003)
Brain
, vol.126
, pp. 230-240
-
-
Marini, C.1
-
93
-
-
0142218355
-
A receptor gene family: New opportunities for drug development
-
A receptor gene family: new opportunities for drug development. Curr. Opin. Drug Discov. Dev. 6:2003;648-657
-
(2003)
Curr. Opin. Drug Discov. Dev.
, vol.6
, pp. 648-657
-
-
Whiting, P.J.1
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