-
1
-
-
0019471017
-
Acetylcholine receptor kinetics
-
Adams, P.R. (1981). Acetylcholine receptor kinetics. J. Membr. Biol. 58, 161-174.
-
(1981)
J. Membr. Biol.
, vol.58
, pp. 161-174
-
-
Adams, P.R.1
-
2
-
-
0027987062
-
Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit
-
Akabas, M.H., Kaufmann, C., Archdeacon, P., and Karlin, A. (1994). Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit. Neuron 13, 919-927.
-
(1994)
Neuron
, vol.13
, pp. 919-927
-
-
Akabas, M.H.1
Kaufmann, C.2
Archdeacon, P.3
Karlin, A.4
-
3
-
-
0028809730
-
Identification of acetylcholine receptor channel-lining residues in the M1 segment of the α-subunit
-
Akabas, M.H., and Karlin, A. (1995). Identification of acetylcholine receptor channel-lining residues in the M1 segment of the α-subunit. Biochemistry 34, 12496-12500.
-
(1995)
Biochemistry
, vol.34
, pp. 12496-12500
-
-
Akabas, M.H.1
Karlin, A.2
-
4
-
-
0015741359
-
Voltage-clamp analysis of acetylcholine produced end-plate current fluctuations at frog neuromuscular junction
-
Anderson, C.R., and Stevens, C.F. (1973). Voltage-clamp analysis of acetylcholine produced end-plate current fluctuations at frog neuromuscular junction. J. Physiol. (Lond.) 235, 655-691.
-
(1973)
J. Physiol. (Lond.)
, vol.235
, pp. 655-691
-
-
Anderson, C.R.1
Stevens, C.F.2
-
5
-
-
0029934560
-
Voltage dependence of mouse acetylcholine receptor gating: Different charge movements in di-, mono-, and unliganded receptors
-
Auerbach, A., Sigurdson, W., Chen, J., and Akk, G. (1996). Voltage dependence of mouse acetylcholine receptor gating: different charge movements in di-, mono-, and unliganded receptors. J. Physiol. 49, 155-170.
-
(1996)
J. Physiol.
, vol.49
, pp. 155-170
-
-
Auerbach, A.1
Sigurdson, W.2
Chen, J.3
Akk, G.4
-
6
-
-
0024278714
-
Helix geometry in proteins
-
Barlow, D.J., and Thornton, J.M. (1988). Helix geometry in proteins. J. Mol. Biol. 201, 601-619.
-
(1988)
J. Mol. Biol.
, vol.201
, pp. 601-619
-
-
Barlow, D.J.1
Thornton, J.M.2
-
7
-
-
0000882208
-
Hypothesis about the function of membrane-buried proline residues in transport proteins
-
Brandi, C.J., and Deber, C.M. (1986). Hypothesis about the function of membrane-buried proline residues in transport proteins. Proc. Natl. Acad. Sci. USA 83, 917-921.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 917-921
-
-
Brandi, C.J.1
Deber, C.M.2
-
8
-
-
0030787794
-
Mutational analysis of backbone hydrogen bonds in staphylococcal nuclease
-
Chapman, E., Thorson, J.S., and Schultz, P.G. (1997). Mutational analysis of backbone hydrogen bonds in staphylococcal nuclease. J. Am. Chem. Soc. 119, 7151-7152.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 7151-7152
-
-
Chapman, E.1
Thorson, J.S.2
Schultz, P.G.3
-
9
-
-
0025355129
-
An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor
-
Charnet, P., Labarca, C., Leonard, R.J., Vogelaar, N.J., Czyzyk, L., Gouin, A., Davidson, N., and Lester, H.A. (1990). An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor. Neuron 2, 87-95.
-
(1990)
Neuron
, vol.2
, pp. 87-95
-
-
Charnet, P.1
Labarca, C.2
Leonard, R.J.3
Vogelaar, N.J.4
Czyzyk, L.5
Gouin, A.6
Davidson, N.7
Lester, H.A.8
-
10
-
-
0017743694
-
Relaxations and fluctuations of membrane currents that flow through drug operated channels
-
Colquhoun, D., and Hawkes, A.G. (1981). Relaxations and fluctuations of membrane currents that flow through drug operated channels. Proc. R. Soc. Lond. B. Biol. Sci. 199, 231-262.
-
(1981)
Proc. R. Soc. Lond. B. Biol. Sci.
, vol.199
, pp. 231-262
-
-
Colquhoun, D.1
Hawkes, A.G.2
-
11
-
-
0026482715
-
Stratified organization of the nicotinic acetylcholine receptor channel
-
Devillers-Thiery, A., Galzi, J.L., Bertrand, S., Changeux, J.P., and Bertrand, D. (1992). Stratified organization of the nicotinic acetylcholine receptor channel. Neuroreport 3, 1001-1004.
-
(1992)
Neuroreport
, vol.3
, pp. 1001-1004
-
-
Devillers-Thiery, A.1
Galzi, J.L.2
Bertrand, S.3
Changeux, J.P.4
Bertrand, D.5
-
12
-
-
0032478818
-
+ conduction and selectivity
-
+ conduction and selectivity. Science 280, 69-77.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.1
Cabrai, J.M.2
Pfuetzner, R.3
Kuo, A.4
Gulbis, J.5
Cohen, S.6
Chait, B.7
MacKinnon, R.8
-
13
-
-
0031745831
-
Allosteric transitions of the acetylcholine receptor
-
Edelstein, S.J., and Changeux, J.P. (1998). Allosteric transitions of the acetylcholine receptor. Adv. Protein Chem. 51, 121-184.
-
(1998)
Adv. Protein Chem.
, vol.51
, pp. 121-184
-
-
Edelstein, S.J.1
Changeux, J.P.2
-
14
-
-
0026567563
-
Site-specific incorporation of novel backbone structures into proteins
-
Ellman, U.A., Mendel, D., and Schultz, P.G. (1992). Site-specific incorporation of novel backbone structures into proteins. Science 255, 197-200.
-
(1992)
Science
, vol.255
, pp. 197-200
-
-
Ellman, U.A.1
Mendel, D.2
Schultz, P.G.3
-
15
-
-
0029123899
-
The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating
-
Filatov, G.N., and White, M .M. (1995). The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating. Mol. Pharmacol. 48, 379-384.
-
(1995)
Mol. Pharmacol.
, vol.48
, pp. 379-384
-
-
Filatov, G.N.1
White, M.M.2
-
16
-
-
0024328738
-
Distance between the agonist and noncompetitive inhibitor sites on the nicotinic acetylcholine receptor
-
Herz, J.M., Johnson, D.A., and Taylor, P. (1989). Distance between the agonist and noncompetitive inhibitor sites on the nicotinic acetylcholine receptor. J. Biol. Chem. 264, 12439-12448.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 12439-12448
-
-
Herz, J.M.1
Johnson, D.A.2
Taylor, P.3
-
18
-
-
0029593370
-
Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins
-
Karlin, A., and Akabas, M.H. (1995). Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins. Neuron 15, 1231-1244.
-
(1995)
Neuron
, vol.15
, pp. 1231-1244
-
-
Karlin, A.1
Akabas, M.H.2
-
19
-
-
0029811223
-
Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: Tests with novel side chains and with several agonists
-
Kearney, P., Nowak, M.W., Zhong, W., Silverman, S.K., Lester, H.A., and Dougherty, D.A. (1996a). Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists. Mol. Pharmacol. 50, 1401-1412.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 1401-1412
-
-
Kearney, P.1
Nowak, M.W.2
Zhong, W.3
Silverman, S.K.4
Lester, H.A.5
Dougherty, D.A.6
-
20
-
-
0030480913
-
Determinants of nicotinic receptor gating in natural and unnatural side chain structures at the M2 9′ position
-
Kearney, P.C., Zhang, H., Zhong, W., Dougherty, D.A., and Lester, H.A. (1996b). Determinants of nicotinic receptor gating in natural and unnatural side chain structures at the M2 9′ position. Neuron 17, 1221-1229.
-
(1996)
Neuron
, vol.17
, pp. 1221-1229
-
-
Kearney, P.C.1
Zhang, H.2
Zhong, W.3
Dougherty, D.A.4
Lester, H.A.5
-
21
-
-
0030922940
-
An experimental approach to evaluating the role of backbone interactions in proteins using unnatural amino acid mutagenesis
-
Koh, J.T., Cornish, V.W., and Schultz, P.G. (1997). An experimental approach to evaluating the role of backbone interactions in proteins using unnatural amino acid mutagenesis. Biochemistry 36, 11314-11322.
-
(1997)
Biochemistry
, vol.36
, pp. 11314-11322
-
-
Koh, J.T.1
Cornish, V.W.2
Schultz, P.G.3
-
22
-
-
0029163027
-
Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors
-
Labarca, C., Nowak, M.W., Zhang, H., Tang, L, Deshpande, P., and Lester, H.A. (1995). Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. Nature 376, 514-516.
-
(1995)
Nature
, vol.376
, pp. 514-516
-
-
Labarca, C.1
Nowak, M.W.2
Zhang, H.3
Tang, L.4
Deshpande, P.5
Lester, H.A.6
-
24
-
-
0015339664
-
The effect of voltage on the time course of end-plate currents
-
Magleby, K.L., and Stevens, C.F. (1972a). The effect of voltage on the time course of end-plate currents. J. Physiol. 223, 151-171.
-
(1972)
J. Physiol.
, vol.223
, pp. 151-171
-
-
Magleby, K.L.1
Stevens, C.F.2
-
25
-
-
0015340428
-
A quantitative description of end-plate currents
-
Magleby, K.L., and Stevens, C.F. (1972b). A quantitative description of end-plate currents. J. Physiol. 223, 173-197.
-
(1972)
J. Physiol.
, vol.223
, pp. 173-197
-
-
Magleby, K.L.1
Stevens, C.F.2
-
26
-
-
0343813520
-
Voltage-dependence of drug-induced conductance in frog neuromuscular junction
-
Neher, E., and Sakmann, B. (1975). Voltage-dependence of drug-induced conductance in frog neuromuscular junction. Proc. Natl. Acad. Sci. USA 72, 2140-2144.
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 2140-2144
-
-
Neher, E.1
Sakmann, B.2
-
27
-
-
0024968835
-
A general method for site-specific incorporation of unnatural amino acids into proteins
-
Noren, C.J., Anthony-Cahill, S.J., Griffith, M.C., and Schultz, P.G. (1989). A general method for site-specific incorporation of unnatural amino acids into proteins. Science 244, 182-188.
-
(1989)
Science
, vol.244
, pp. 182-188
-
-
Noren, C.J.1
Anthony-Cahill, S.J.2
Griffith, M.C.3
Schultz, P.G.4
-
28
-
-
0029005830
-
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells
-
Nowak, M.W., Kearney, P.C., Sampson, J.R., Saks, M.E., Labarca, C.G., Silverman, S.K., Zhong, W., Thorson, J., Abelson, J.N., Davidson, N., et al. (1995). Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells. Science 268, 439-442.
-
(1995)
Science
, vol.268
, pp. 439-442
-
-
Nowak, M.W.1
Kearney, P.C.2
Sampson, J.R.3
Saks, M.E.4
Labarca, C.G.5
Silverman, S.K.6
Zhong, W.7
Thorson, J.8
Abelson, J.N.9
Davidson, N.10
-
29
-
-
0032311418
-
In vivo incorporation of unnatural amino acids into ion channels in a Xenopus oocyte expression system
-
Nowak, M.W., Gallivan, J.P., Silverman, S.K., Labarca, C.G., Dougherty, D.A., and Lester, H.A. (1998). In vivo incorporation of unnatural amino acids into ion channels in a Xenopus oocyte expression system. Methods Enzymol. 293, 504-529.
-
(1998)
Methods Enzymol.
, vol.293
, pp. 504-529
-
-
Nowak, M.W.1
Gallivan, J.P.2
Silverman, S.K.3
Labarca, C.G.4
Dougherty, D.A.5
Lester, H.A.6
-
30
-
-
0026079817
-
Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor
-
Revah, F., Bertrand, D., Galzi, J.L, Devillers-Theiry, A., and Mulle, C. (1991). Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor. Nature 353, 846-849.
-
(1991)
Nature
, vol.353
, pp. 846-849
-
-
Revah, F.1
Bertrand, D.2
Galzi, J.L.3
Devillers-Theiry, A.4
Mulle, C.5
-
31
-
-
0029661426
-
An engineered Tetrahymena tRNAGIn for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression
-
Saks, M.E., Sampson, J.R., Nowak, M.W., Kearney, P.C., Du, F., Abelson, J.N., Lester, H.A., and Dougherty, D.A. (1996). An engineered Tetrahymena tRNAGIn for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression. J. Biol. Chem. 271, 23169-23175.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23169-23175
-
-
Saks, M.E.1
Sampson, J.R.2
Nowak, M.W.3
Kearney, P.C.4
Du, F.5
Abelson, J.N.6
Lester, H.A.7
Dougherty, D.A.8
-
33
-
-
0017646559
-
Rates and equilibria at the acetylcholine receptor of Electrophorus electroplaques. A study of neurally evoked postsynaptic currents and of voltage-jump relaxations
-
Sheridan, R.E., and Lester, H.A. (1977). Rates and equilibria at the acetylcholine receptor of Electrophorus electroplaques. A study of neurally evoked postsynaptic currents and of voltage-jump relaxations. J. Gen. Physiol. 70, 187-219.
-
(1977)
J. Gen. Physiol.
, vol.70
, pp. 187-219
-
-
Sheridan, R.E.1
Lester, H.A.2
-
34
-
-
0029087136
-
Mutation of the acetylcholine receptor α subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity
-
Sine, S.M., Ohno, K., Bouzat, C., Auerbach, A., Milone, M., Pruitt, J.N., and Engel, A.G. (1995). Mutation of the acetylcholine receptor α subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity. Neuron 15, 229-239.
-
(1995)
Neuron
, vol.15
, pp. 229-239
-
-
Sine, S.M.1
Ohno, K.2
Bouzat, C.3
Auerbach, A.4
Milone, M.5
Pruitt, J.N.6
Engel, A.G.7
-
35
-
-
0027506299
-
Nicotinic acetylcholine receptor at 9-Å resolution
-
Unwin, N. (1993). Nicotinic acetylcholine receptor at 9-Å resolution. J. Mol. Biol. 229, 1101-1124.
-
(1993)
J. Mol. Biol.
, vol.229
, pp. 1101-1124
-
-
Unwin, N.1
-
36
-
-
0028921479
-
Acetylcholine receptor channel imaged in the open state
-
Unwin, N. (1995). Acetylcholine receptor channel imaged in the open state. Nature 373, 37-43.
-
(1995)
Nature
, vol.373
, pp. 37-43
-
-
Unwin, N.1
-
37
-
-
0030906795
-
Mutation in the M1 domain of the acetylcholine receptor α subunit decreases the rate of agonist dissociation
-
Wang, H.L., Auerbach, A., Bren, N., Ohno, K., Engel, A.G., and Sine, S.M. (1997). Mutation in the M1 domain of the acetylcholine receptor α subunit decreases the rate of agonist dissociation. J. Gen. Physiol. 109, 757-766.
-
(1997)
J. Gen. Physiol.
, vol.109
, pp. 757-766
-
-
Wang, H.L.1
Auerbach, A.2
Bren, N.3
Ohno, K.4
Engel, A.G.5
Sine, S.M.6
-
38
-
-
0032102496
-
The location of the gate in the acetylcholine receptor channel
-
Wilson, G.G., and Karlin, A. (1998). The location of the gate in the acetylcholine receptor channel. Neuron 20, 1269-1281.
-
(1998)
Neuron
, vol.20
, pp. 1269-1281
-
-
Wilson, G.G.1
Karlin, A.2
-
39
-
-
0027439867
-
Proline-dependent structural and biological properties of peptides and proteins
-
Yaron, A., and Naider, F. (1993). Proline-dependent structural and biological properties of peptides and proteins. Crit. Rev. Biochem. Mol. Biol. 28, 31-81.
-
(1993)
Crit. Rev. Biochem. Mol. Biol.
, vol.28
, pp. 31-81
-
-
Yaron, A.1
Naider, F.2
-
40
-
-
0031456382
-
Identification of acetylcholine receptor channel-lining residues in the M1 segment of the β-subunit
-
Zhang, H., and Karlin, A. (1997). Identification of acetylcholine receptor channel-lining residues in the M1 segment of the β-subunit. Biochemistry 36, 15856-15864.
-
(1997)
Biochemistry
, vol.36
, pp. 15856-15864
-
-
Zhang, H.1
Karlin, A.2
-
41
-
-
0032514762
-
From ab initio quantum mechanics to molecular neurobiology: A cation-π binding site in the nicotinic receptor
-
Zhong, W., Gallivan, J.P., Zhang, Y., Li, L., Lester, H.A., and Dougherty, D.A. (1998). From ab initio quantum mechanics to molecular neurobiology: a cation-π binding site in the nicotinic receptor. Proc. Natl. Acad. Sci. USA 95, 12088-12093.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12088-12093
-
-
Zhong, W.1
Gallivan, J.P.2
Zhang, Y.3
Li, L.4
Lester, H.A.5
Dougherty, D.A.6
|