The structure and function of G-protein-coupled receptors

Nature

Volumn 459, Issue 7245, 2009, Pages 356-363

  Rosenbaum, Daniel M ^a   Rasmussen, Søren G F ^a   Kobilka, Brian K ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

11 CIS RETINAL; ADENOSINE A2 RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ADRENALIN; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CARAZOLOL; CENTRAL STIMULANT AGENT; CYANOPINDOLOL; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GLUTAMIC ACID; HORMONE; LYSINE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTRANSMITTER; NORADRENALIN; PROLINE; RETINA S ANTIGEN; RHODOPSIN; SCHIFF BASE; TIMOLOL; TYROSINE;

DISEASE TREATMENT; HORMONE; MOLECULAR ANALYSIS; PROTEIN;

AGONIST; ALPHA HELIX; BETA SHEET; BINDING SITE; CONFORMATIONAL TRANSITION; COVALENT BOND; CRYSTAL STRUCTURE; DISULFIDE BOND; DRUG PROTEIN BINDING; ELECTRON SPIN RESONANCE; EXTRACELLULAR MATRIX; LIGAND BINDING; LIPID BILAYER; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; SPECTRUM; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; CONSERVED SEQUENCE; CYTOPLASM; HUMANS; OPSINS; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 66249144426     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08144     Document Type: Review

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