Mapping the ligand-binding site on a G protein-coupled receptor (GPCR) using genetically encoded photocrosslinkers

Biochemistry

Volumn 50, Issue 17, 2011, Pages 3411-3413

  Grunbeck, Amy ^a   Huber, Thomas ^a   Sachdev, Pallavi ^a   Sakmar, Thomas P ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMBER CODONS; BINDING INTERFACE; CROSSLINKS; CXC CHEMOKINE RECEPTOR 4; G-PROTEIN COUPLED RECEPTORS; GENERAL CELL; L-PHENYLALANINE; LIGAND-BINDING SITES; PHOTOACTIVATABLE; PHOTOCROSS-LINKING APPROACH; SIGNALING COMPLEX; UV-LIGHT;

CRYSTAL STRUCTURE; LIGANDS;

AMINO ACIDS;

CHEMOKINE RECEPTOR CXCR4; G PROTEIN COUPLED RECEPTOR; T 140;

ARTICLE; BINDING SITE; COMPLEX FORMATION; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR MODEL; PHOTOCROSSLINKING; PRIORITY JOURNAL; PROTEIN CROSS LINKING; SIGNAL TRANSDUCTION;

AZIDES; BENZOPHENONES; BINDING SITES; CROSS-LINKING REAGENTS; FLUORESCEINS; FLUORESCENT DYES; HEK293 CELLS; HIV-1; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTATION; OLIGOPEPTIDES; PHENYLALANINE; PROTEIN BINDING; RECEPTORS, CXCR4; ULTRAVIOLET RAYS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 79955445476     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200214r     Document Type: Article

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