-
2
-
-
0035866070
-
Structural determinants of fast desensitization and desensitization- deactivation coupling in GABAa receptors
-
Bianchi M. T., Haas K. F. Macdonald R. L. (2001) Structural determinants of fast desensitization and desensitization-deactivation coupling in GABAa receptors. J. Neurosci. 21, 1127 1136.
-
(2001)
J. Neurosci.
, vol.21
, pp. 1127-1136
-
-
Bianchi, M.T.1
Haas, K.F.2
MacDonald, R.L.3
-
3
-
-
18444411922
-
Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors
-
Bourne Y., Talley T. T., Hansen S. B., Taylor P. Marchot P. (2005) Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors. EMBO J. 24, 1512 1522.
-
(2005)
EMBO J.
, vol.24
, pp. 1512-1522
-
-
Bourne, Y.1
Talley, T.T.2
Hansen, S.B.3
Taylor, P.4
Marchot, P.5
-
4
-
-
50349093448
-
The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization
-
Bouzat C., Bartos M., Corradi J. Sine S. M. (2008) The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization. J. Neurosci. 28, 7808 7819.
-
(2008)
J. Neurosci.
, vol.28
, pp. 7808-7819
-
-
Bouzat, C.1
Bartos, M.2
Corradi, J.3
Sine, S.M.4
-
5
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc K., van Dijk W. J., Klaassen R. V., Schuurmans M., van Der Oost J., Smit A. B. Sixma T. K. (2001) Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature 411, 269 276.
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
Van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
Van Der Oost, J.5
Smit, A.B.6
Sixma, T.K.7
-
6
-
-
10044248233
-
Single-channel behavior of heteromeric alpha1beta glycine receptors: An attempt to detect a conformational change before the channel opens
-
Burzomato V., Beato M., Groot-Kormelink P. J., Colquhoun D. Sivilotti L. G. (2004) Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens. J. Neurosci. 24, 10924 10940.
-
(2004)
J. Neurosci.
, vol.24
, pp. 10924-10940
-
-
Burzomato, V.1
Beato, M.2
Groot-Kormelink, P.J.3
Colquhoun, D.4
Sivilotti, L.G.5
-
7
-
-
22144470470
-
Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant
-
Celie P. H., Kasheverov I. E., Mordvintsev D. Y. et al. (2005) Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant. Nat. Struct. Mol. Biol. 12, 582 588.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 582-588
-
-
Celie, P.H.1
Kasheverov, I.E.2
Mordvintsev, D.Y.3
-
8
-
-
0036830645
-
Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism
-
Chang Y. Weiss D. S. (2002) Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism. Nat. Neurosci. 5, 1163 1168.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 1163-1168
-
-
Chang, Y.1
Weiss, D.S.2
-
9
-
-
0032215090
-
Allosteric receptors after 30 years
-
Changeux J. P. Edelstein S. J. (1998) Allosteric receptors after 30 years. Neuron 21, 959 980.
-
(1998)
Neuron
, vol.21
, pp. 959-980
-
-
Changeux, J.P.1
Edelstein, S.J.2
-
11
-
-
3042829624
-
A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site
-
Dahan D. S., Dibas M. I., Petersson E. J., Auyeung V. C., Chanda B., Bezanilla F., Dougherty D. A. Lester H. A. (2004) A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site. Proc. Natl Acad. Sci. USA 101, 10195 10200.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 10195-10200
-
-
Dahan, D.S.1
Dibas, M.I.2
Petersson, E.J.3
Auyeung, V.C.4
Chanda, B.5
Bezanilla, F.6
Dougherty, D.A.7
Lester, H.A.8
-
12
-
-
0037124034
-
Point mutation in the first transmembrane region of the beta 2 subunit of the gamma - Aminobutyric acid type A receptor alters desensitization kinetics of gamma - Aminobutyric acid- and anesthetic-induced channel gating
-
Engblom A. C., Carlson B. X., Olsen R. W., Schousboe A. Kristiansen U. (2002) Point mutation in the first transmembrane region of the beta 2 subunit of the gamma - aminobutyric acid type A receptor alters desensitization kinetics of gamma - aminobutyric acid- and anesthetic-induced channel gating. J. Biol. Chem. 277, 17438 17447.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17438-17447
-
-
Engblom, A.C.1
Carlson, B.X.2
Olsen, R.W.3
Schousboe, A.4
Kristiansen, U.5
-
13
-
-
0034677524
-
Mapping the conformational wave of acetylcholine receptor channel gating
-
Grosman C., Zhou M. Auerbach A. (2000) Mapping the conformational wave of acetylcholine receptor channel gating. Nature 403, 773 776.
-
(2000)
Nature
, vol.403
, pp. 773-776
-
-
Grosman, C.1
Zhou, M.2
Auerbach, A.3
-
14
-
-
14644414132
-
The beta subunit determines the ligand binding properties of synaptic glycine receptors
-
Grudzinska J., Schemm R., Haeger S., Nicke A., Schmalzing G., Betz H. Laube B. (2005) The beta subunit determines the ligand binding properties of synaptic glycine receptors. Neuron 45, 727 739.
-
(2005)
Neuron
, vol.45
, pp. 727-739
-
-
Grudzinska, J.1
Schemm, R.2
Haeger, S.3
Nicke, A.4
Schmalzing, G.5
Betz, H.6
Laube, B.7
-
15
-
-
27144473613
-
Structures of aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
-
Hansen S. B., Sulzenbacher G., Huxford T., Marchot P., Taylor P. Bourne Y. (2005) Structures of aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. EMBO J. 24, 3635 3646.
-
(2005)
EMBO J.
, vol.24
, pp. 3635-3646
-
-
Hansen, S.B.1
Sulzenbacher, G.2
Huxford, T.3
Marchot, P.4
Taylor, P.5
Bourne, Y.6
-
16
-
-
0036480194
-
Emerging structure of the nicotinic acetylcholine receptors
-
Karlin A. (2002) Emerging structure of the nicotinic acetylcholine receptors. Nat. Rev. Neurosci. 3, 102 114.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 102-114
-
-
Karlin, A.1
-
17
-
-
0036683420
-
Ion channels: Does each subunit do something on its own?
-
Karpen J. W. Ruiz M. (2002) Ion channels: does each subunit do something on its own? Trends Biochem. Sci. 27, 402 409.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 402-409
-
-
Karpen, J.W.1
Ruiz, M.2
-
18
-
-
0034929661
-
Neurotransmitter receptor trafficking and the regulation of synaptic strength
-
Kittler J. T. Moss S. J. (2001) Neurotransmitter receptor trafficking and the regulation of synaptic strength. Traffic 2, 437 448.
-
(2001)
Traffic
, vol.2
, pp. 437-448
-
-
Kittler, J.T.1
Moss, S.J.2
-
19
-
-
49649102025
-
On the nature of partial agonism in the nicotinic receptor superfamily
-
Lape R., Colquhoun D. Sivilotti L. G. (2008) On the nature of partial agonism in the nicotinic receptor superfamily. Nature 454, 722 727.
-
(2008)
Nature
, vol.454
, pp. 722-727
-
-
Lape, R.1
Colquhoun, D.2
Sivilotti, L.G.3
-
20
-
-
0035968423
-
The ligand gated ion channel database: An example of a sequence database in neuroscience
-
Le Novere N. Changeux J. P. (2001) The ligand gated ion channel database: an example of a sequence database in neuroscience. Philos. Trans. R. Soc. Lond. B Biol. Sci. 356, 1121 1130.
-
(2001)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.356
, pp. 1121-1130
-
-
Le Novere, N.1
Changeux, J.P.2
-
21
-
-
0036771640
-
Desensitization of homomeric alpha1 glycine receptor increases with receptor density
-
Legendre P., Muller E., Badiu C. I., Meier J., Vannier C. Triller A. (2002) Desensitization of homomeric alpha1 glycine receptor increases with receptor density. Mol. Pharmacol. 62, 817 827.
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 817-827
-
-
Legendre, P.1
Muller, E.2
Badiu, C.I.3
Meier, J.4
Vannier, C.5
Triller, A.6
-
22
-
-
0030059224
-
Direct physical measure of conformational rearrangement underlying potassium channel gating
-
Mannuzzu L. M., Moronne M. M. Isacoff E. Y. (1996) Direct physical measure of conformational rearrangement underlying potassium channel gating. Science 271, 213 216.
-
(1996)
Science
, vol.271
, pp. 213-216
-
-
Mannuzzu, L.M.1
Moronne, M.M.2
Isacoff, E.Y.3
-
23
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
Miyazawa A., Fujiyoshi Y. Unwin N. (2003) Structure and gating mechanism of the acetylcholine receptor pore. Nature 423, 949 955.
-
(2003)
Nature
, vol.423
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
24
-
-
33745015539
-
Local and global ligand-induced changes in the structure of the GABA(A) receptor
-
Muroi Y., Czajkowski C. Jackson M. B. (2006) Local and global ligand-induced changes in the structure of the GABA(A) receptor. Biochem. 45, 7013 7022.
-
(2006)
Biochem.
, vol.45
, pp. 7013-7022
-
-
Muroi, Y.1
Czajkowski, C.2
Jackson, M.B.3
-
25
-
-
0347064158
-
Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: Effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons
-
Nashmi R., Dickinson M. E., McKinney S., Jareb M., Labarca C., Fraser S. E. Lester H. A. (2003) Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons. J. Neurosci. 23, 11554 11567.
-
(2003)
J. Neurosci.
, vol.23
, pp. 11554-11567
-
-
Nashmi, R.1
Dickinson, M.E.2
McKinney, S.3
Jareb, M.4
Labarca, C.5
Fraser, S.E.6
Lester, H.A.7
-
26
-
-
50649099067
-
Illuminating the structure and function of Cys-loop receptors
-
Pless S. A. Lynch J. W. (2008) Illuminating the structure and function of Cys-loop receptors. Clin. Exp. Pharmacol. Physiol. 35, 1137 1142.
-
(2008)
Clin. Exp. Pharmacol. Physiol.
, vol.35
, pp. 1137-1142
-
-
Pless, S.A.1
Lynch, J.W.2
-
27
-
-
37249027595
-
Conformational variability of the glycine receptor M2 domain in response to activation by different agonists
-
Pless S. A., Dibas M. I., Lester H. A. Lynch J. W. (2007) Conformational variability of the glycine receptor M2 domain in response to activation by different agonists. J. Biol. Chem. 282, 36057 36067.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36057-36067
-
-
Pless, S.A.1
Dibas, M.I.2
Lester, H.A.3
Lynch, J.W.4
-
28
-
-
0029027617
-
The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element
-
Rajendra S., Vandenberg R. J., Pierce K. D., Cunningham A. M., French P. W., Barry P. H. Schofield P. R. (1995) The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element. EMBO J. 14, 2987 2998.
-
(1995)
EMBO J.
, vol.14
, pp. 2987-2998
-
-
Rajendra, S.1
Vandenberg, R.J.2
Pierce, K.D.3
Cunningham, A.M.4
French, P.W.5
Barry, P.H.6
Schofield, P.R.7
-
29
-
-
49649105529
-
The ubiquitin-like protein Plic-1 enhances the membrane insertion of GABAA receptors by increasing their stability within the endoplasmic reticulum
-
Saliba R. S., Pangalos M. Moss S. J. (2008) The ubiquitin-like protein Plic-1 enhances the membrane insertion of GABAA receptors by increasing their stability within the endoplasmic reticulum. J. Biol. Chem. 283, 18538 18544.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 18538-18544
-
-
Saliba, R.S.1
Pangalos, M.2
Moss, S.J.3
-
30
-
-
0028207959
-
Expression of the human glycine receptor alpha1 subunit in Xenopus oocytes: Apparent affinities of agonists increase at high receptor density
-
Taleb O. Betz H. (1994) Expression of the human glycine receptor alpha1 subunit in Xenopus oocytes: apparent affinities of agonists increase at high receptor density. EMBO J. 13, 1318 1324.
-
(1994)
EMBO J.
, vol.13
, pp. 1318-1324
-
-
Taleb, O.1
Betz, H.2
-
31
-
-
42949161115
-
Up-regulation of nicotinic receptors by nicotine varies with receptor subtype
-
Walsh H., Govind A. P., Mastro R., Hoda J. C., Bertrand D., Vallejo Y. Green W. N. (2008) Up-regulation of nicotinic receptors by nicotine varies with receptor subtype. J. Biol. Chem. 283, 6022 6032.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 6022-6032
-
-
Walsh, H.1
Govind, A.P.2
Mastro, R.3
Hoda, J.C.4
Bertrand, D.5
Vallejo, Y.6
Green, W.N.7
-
32
-
-
33645212296
-
Mechanisms for picrotoxin block of alpha2 homomeric glycine receptors
-
Wang D. S., Mangin J. M., Moonen G., Rigo J. M. Legendre P. (2006) Mechanisms for picrotoxin block of alpha2 homomeric glycine receptors. J. Biol. Chem. 281, 3841 3855.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 3841-3855
-
-
Wang, D.S.1
Mangin, J.M.2
Moonen, G.3
Rigo, J.M.4
Legendre, P.5
-
33
-
-
34447524895
-
Mechanisms for picrotoxinin and picrotin block of alpha2 homomeric glycine receptors
-
Wang D. S., Buckinx R., Lecorronc H., Mangin J. M., Rigo J. M. Legendre P. (2007) Mechanisms for picrotoxinin and picrotin block of alpha2 homomeric glycine receptors. J. Biol. Chem. 282, 16016 16035.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 16016-16035
-
-
Wang, D.S.1
Buckinx, R.2
Lecorronc, H.3
Mangin, J.M.4
Rigo, J.M.5
Legendre, P.6
|