Probing the role of backbone hydrogen bonding in a critical β sheet of the extracellular domain of a cys-loop receptor

ChemBioChem

Volumn 10, Issue 8, 2009, Pages 1385-1391

  Gleitsman, Kristin R ^a   Lester, Henry A ^b   Dougherty, Dennis A ^a  

^a California Institute of Technology   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Allosterism; Backbone esters; Ion channels; Mutagenesis; Receptors

Indexed keywords

2 HYDROXYACID; CYSTEINE LOOP RECEPTOR; HYDROGEN; ION CHANNEL; MEMBRANE PROTEIN; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BETA SHEET; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FLUORESCENCE MICROSCOPY; HYDROGEN BOND; MUTATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; XENOPUS LAEVIS; CHEMISTRY; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

HYDROGEN BONDING; ION CHANNEL GATING; MUTATION; NEUROTRANSMITTER AGENTS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, NICOTINIC;

EID: 67651160556     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200900092     Document Type: Article

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