An electrostatic interaction between TEA and an introduced pore aromatic drives spring-in-the-door inactivation in Shaker potassium channels

Journal of General Physiology

Volumn 134, Issue 6, 2009, Pages 461-469

  Ahern, Christopher A ^a   Eastwood, Amy L ^b   Dougherty, Dennis A ^b   Horn, Richard ^c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b California Institute of Technology   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; FLUORINE; PHENYLALANINE; SHAKER POTASSIUM CHANNEL; TETRYLAMMONIUM; THREONINE; VALINE;

ALLOSTERISM; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CALCULATION; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELECTRICITY; FLUORINATION; NONHUMAN; PROTEIN CONFORMATION; QUANTUM MECHANICS; SLOW CHANNEL INACTIVATION;

ADENOSINE DIPHOSPHATE RIBOSE; ANIMALS; BINDING SITES; CALCIUM; ION CHANNEL GATING; OOCYTES; POTASSIUM CHANNEL BLOCKERS; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAETHYLAMMONIUM; XENOPUS LAEVIS;

EID: 73149086415     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.200910260     Document Type: Article

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