-
1
-
-
15244352867
-
The external TEA binding site and C-type inactivation in voltage-gated potassium channels
-
Andalib, P., J.F. Consiglio, J.G. Trapani, and S.J. Korn. 2004. The external TEA binding site and C-type inactivation in voltage-gated potassium channels. Biophys. J. 87:3148-3161.
-
(2004)
Biophys. J.
, vol.87
, pp. 3148-3161
-
-
Andalib, P.1
Consiglio, J.F.2
Trapani, J.G.3
Korn, S.J.4
-
2
-
-
0015142234
-
Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons
-
Armstrong, C.M. 1971. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons. J. Gen. Physiol. 58:413-437.
-
(1971)
J. Gen. Physiol.
, vol.58
, pp. 413-437
-
-
Armstrong, C.M.1
-
3
-
-
0037072311
-
Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: The anomalous binding properties of nicotine
-
Beene, D.L., G.S. Brandt, W. Zhong, N.M. Zacharias, H.A. Lester, and D.A. Dougherty. 2002. Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine. Biochemistry. 41:10262-10269.
-
(2002)
Biochemistry
, vol.41
, pp. 10262-10269
-
-
Beene, D.L.1
Brandt, G.S.2
Zhong, W.3
Zacharias, N.M.4
Lester, H.A.5
Dougherty, D.A.6
-
4
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc, K., W. J. van Dijk, R.V. Klaassen, M. Schuurmans, J. van Der Oost, A.B. Smit, and T.K. Sixma. 2001. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature. 411:269-276.
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
Van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
Van Der Oost, J.5
Smit, A.B.6
Sixma, T.K.7
-
5
-
-
0032991264
-
External tetraethylammonium as a molecular caliper for sensing the shape of the outer vestibule of potassium channels
-
Bretschneider, F., A. Wrisch, F. Lehmann-Horn, and S. Grissmer. 1999. External tetraethylammonium as a molecular caliper for sensing the shape of the outer vestibule of potassium channels. Biophys. J. 76:2351-2360.
-
(1999)
Biophys. J.
, vol.76
, pp. 2351-2360
-
-
Bretschneider, F.1
Wrisch, A.2
Lehmann-Horn, F.3
Grissmer, S.4
-
6
-
-
24644508800
-
The pore helix dipole has a minor role in inward rectifier channel function
-
Chatelain, F.C., N. Alagem, Q. Xu, R. Pancaroglu, E. Reuveny, and D.L. Minor Jr. 2005. The pore helix dipole has a minor role in inward rectifier channel function. Neuron. 47:833-843.
-
(2005)
Neuron
, vol.47
, pp. 833-843
-
-
Chatelain, F.C.1
Alagem, N.2
Xu, Q.3
Pancaroglu, R.4
Reuveny, E.5
Minor Jr., D.L.6
-
8
-
-
33745041507
-
Molecular determinants of gating at the potassium-channel selectivity filter
-
Cordero-Morales, J.F., L.G. Cuello, Y. Zhao, V. Jogini, D.M. Cortes, B. Roux, and E. Perozo. 2006. Molecular determinants of gating at the potassium-channel selectivity filter. Nat. Struct. Mol. Biol. 13:311-318.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 311-318
-
-
Cordero-Morales, J.F.1
Cuello, L.G.2
Zhao, Y.3
Jogini, V.4
Cortes, D.M.5
Roux, B.6
Perozo, E.7
-
9
-
-
0000512620
-
Polarizability anisotropy, magnetic anisotropy, and quadrupole moment of cyclohexane
-
Craven, I.E., M.R. Hesling, D.R. Laver, P.B. Lukins, G.L.D. Ritchie, and J. Vrbancich. 1989. Polarizability anisotropy, magnetic anisotropy, and quadrupole moment of cyclohexane. J. Phys. Chem. 93:627-631.
-
(1989)
J. Phys. Chem.
, vol.93
, pp. 627-631
-
-
Craven, I.E.1
Hesling, M.R.2
Laver, D.R.3
Lukins, P.B.4
Ritchie, G.L.D.5
Vrbancich, J.6
-
10
-
-
0034880289
-
+ channels by TEA: Results from molecular dynamics simulations of the KcsA channel
-
+ channels by TEA: results from molecular dynamics simulations of the KcsA channel. J. Gen. Physiol. 118:207-217.
-
(2001)
J. Gen. Physiol.
, vol.118
, pp. 207-217
-
-
Crouzy, S.1
Bernèche, S.2
Roux, B.3
-
11
-
-
0030043489
-
Cation-pi interactions in chemistry and biology: A new view of benzene, Phe, Tyr, and Trp
-
Dougherty, D.A. 1996. Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. Science. 271:163-168.
-
(1996)
Science
, vol.271
, pp. 163-168
-
-
Dougherty, D.A.1
-
12
-
-
0032478818
-
+ conduction and selectivity
-
+ conduction and selectivity. Science. 280:69-77.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Cabral, J.M.2
Pfuetzner, R.A.3
Kuo, A.L.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
13
-
-
1842326139
-
Bayesian statistical analysis of protein side-chain rotamer preferences
-
Dunbrack, R.L., Jr., and F.E. Cohen. 1997. Bayesian statistical analysis of protein side-chain rotamer preferences. Protein Sci. 6:1661-1681.
-
(1997)
Protein Sci.
, vol.6
, pp. 1661-1681
-
-
Dunbrack Jr., R.L.1
Cohen, F.E.2
-
14
-
-
0024393637
-
A novel potassium channel with delayed rectifier properties rat brain by expression cloning
-
Frech, G.C., A.M. VanDongen, G. Schuster, A.M. Brown, and R.H. Joho. 1989. A novel potassium channel with delayed rectifier properties rat brain by expression cloning. Nature. 340:642-645.
-
(1989)
Nature
, vol.340
, pp. 642-645
-
-
Frech, G.C.1
VanDongen, A.M.2
Schuster, G.3
Brown, A.M.4
Joho, R.H.5
-
15
-
-
0036973095
-
Tetraethylammonium binding to the outer mouth of the KcsA potassium channel: Implications for ion permeation
-
Guidoni, L., and P. Carloni. 2002. Tetraethylammonium binding to the outer mouth of the KcsA potassium channel: implications for ion permeation. J. Recept. Signal Transduct. Res. 22:315-331.
-
(2002)
J. Recept. Signal Transduct. Res.
, vol.22
, pp. 315-331
-
-
Guidoni, L.1
Carloni, P.2
-
16
-
-
0026560616
-
The aromatic binding site for tetraethylammonium ion on potassium channels
-
Heginbotham, L., and R. MacKinnon. 1992. The aromatic binding site for tetraethylammonium ion on potassium channels. Neuron. 8:483-491.
-
(1992)
Neuron
, vol.8
, pp. 483-491
-
-
Heginbotham, L.1
MacKinnon, R.2
-
18
-
-
0028987938
-
+ channel pore through mutant cycles with a peptide inhibitor
-
+ channel pore through mutant cycles with a peptide inhibitor. Science. 268:307-310.
-
(1995)
Science
, vol.268
, pp. 307-310
-
-
Hidalgo, P.1
MacKinnon, R.2
-
19
-
-
0014089361
-
The selective inhibition of delayed potassium currents in nerve by tetraethylammonium ion
-
Hille, B. 1967. The selective inhibition of delayed potassium currents in nerve by tetraethylammonium ion. J. Gen. Physiol. 50:1287-1302.
-
(1967)
J. Gen. Physiol.
, vol.50
, pp. 1287-1302
-
-
Hille, B.1
-
20
-
-
0029125627
-
Influence of permeating ions on potassium channel block by external tetraethylammonium
-
Ikeda, S.R., and S.J. Korn. 1995. Influence of permeating ions on potassium channel block by external tetraethylammonium. J. Physiol. 486:267-272.
-
(1995)
J. Physiol.
, vol.486
, pp. 267-272
-
-
Ikeda, S.R.1
Korn, S.J.2
-
21
-
-
0033823118
-
The barium site in a potassium channel by x-ray crystallography
-
Jiang, Y., and R. MacKinnon. 2000. The barium site in a potassium channel by x-ray crystallography. J. Gen. Physiol. 115:269-272.
-
(2000)
J. Gen. Physiol.
, vol.115
, pp. 269-272
-
-
Jiang, Y.1
MacKinnon, R.2
-
22
-
-
0025743037
-
Interaction between tetraethylammonium and amino acid residues in the pore of cloned voltage-dependent potassium channels
-
Kavanaugh, M.P., M.D. Varnum, P.B. Osborne, M.J. Christie, A.E. Busch, J.P. Adelman, and R.A. North. 1991. Interaction between tetraethylammonium and amino acid residues in the pore of cloned voltage-dependent potassium channels. J. Biol. Chem. 266:7583-7587.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 7583-7587
-
-
Kavanaugh, M.P.1
Varnum, M.D.2
Osborne, P.B.3
Christie, M.J.4
Busch, A.E.5
Adelman, J.P.6
North, R.A.7
-
23
-
-
0027436998
-
A mechanism for ion selectivity in potassium channels: Computational studies of cation-π interactions
-
Kumpf, R.A., and D.A. Dougherty. 1993. A mechanism for ion selectivity in potassium channels: computational studies of cation-π interactions. Science. 261:1708-1710.
-
(1993)
Science
, vol.261
, pp. 1708-1710
-
-
Kumpf, R.A.1
Dougherty, D.A.2
-
24
-
-
20444466121
-
Structural basis of TEA blockade in a model potassium channel
-
Lenaeus, M.J., M. Vamvouka, P.J. Focia, and A. Gross. 2005. Structural basis of TEA blockade in a model potassium channel. Nat. Struct. Mol. Biol. 12:454-459.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 454-459
-
-
Lenaeus, M.J.1
Vamvouka, M.2
Focia, P.J.3
Gross, A.4
-
25
-
-
8644243613
-
Partition coefficients and their uses
-
Leo, A., C. Hansch, and D. Elkins. 1971. Partition coefficients and their uses. Chem. Rev. 71:525-616.
-
(1971)
Chem. Rev.
, vol.71
, pp. 525-616
-
-
Leo, A.1
Hansch, C.2
Elkins, D.3
-
26
-
-
25144465496
-
A cation:π binding interaction with a tyrosine in the binding site of the GABAc receptor
-
Lummis, S.C., D.L. Beene, N.L. Harrison, H.A. Lester, and D.A. Dougherty. 2005. A cation:π binding interaction with a tyrosine in the binding site of the GABAc receptor. Chem. Biol. 12:993-997.
-
(2005)
Chem. Biol.
, vol.12
, pp. 993-997
-
-
Lummis, S.C.1
Beene, D.L.2
Harrison, N.L.3
Lester, H.A.4
Dougherty, D.A.5
-
27
-
-
0035957732
-
Mechanisms of tetraethylammonium ion block in the KcsA potassium channel
-
Luzhkov, V.B., and J. Aqvist. 2001. Mechanisms of tetraethylammonium ion block in the KcsA potassium channel. FEBS Lett. 495:191-196.
-
(2001)
FEBS Lett.
, vol.495
, pp. 191-196
-
-
Luzhkov, V.B.1
Aqvist, J.2
-
28
-
-
0142246586
-
Structure-activity relationship for extracellular block of K+ channels by tetraalkylammonium ions
-
Luzhkov, V.B., F. Osterberg, and J. Aqvist. 2003. Structure-activity relationship for extracellular block of K+ channels by tetraalkylammonium ions. FEBS Lett. 554:159-164.
-
(2003)
FEBS Lett.
, vol.554
, pp. 159-164
-
-
Luzhkov, V.B.1
Osterberg, F.2
Aqvist, J.3
-
29
-
-
4243468938
-
The cation-π interaction
-
Ma, J.C., and D.A. Dougherty. 1997. The cation-π interaction. Chem. Rev. 97:1303-1324.
-
(1997)
Chem. Rev.
, vol.97
, pp. 1303-1324
-
-
Ma, J.C.1
Dougherty, D.A.2
-
32
-
-
0029745052
-
Cation-pi interactions in aromatics of biological and medicinal interest: Electrostatic potential surfaces as a useful qualitative guide
-
Mecozzi, S., A.P. West Jr., and D.A. Dougherty. 1996a. Cation-pi interactions in aromatics of biological and medicinal interest: electrostatic potential surfaces as a useful qualitative guide. Proc. Natl. Acad. Sci. USA. 93:10566-10571.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10566-10571
-
-
Mecozzi, S.1
West Jr., A.P.2
Dougherty, D.A.3
-
33
-
-
0029967521
-
Cation-π interactions in simple aromatics: Electrostatics provide a predictive tool
-
Mecozzi, S., A.P. West Jr., and D.A. Dougherty. 1996b. Cation-π interactions in simple aromatics: electrostatics provide a predictive tool. J. Am. Chem. Soc. 118:2307-2308.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 2307-2308
-
-
Mecozzi, S.1
West Jr., A.P.2
Dougherty, D.A.3
-
35
-
-
0030993829
-
+ channels distinguish between the sites of tetraethylammonium blockade and C-type inactivation
-
+ channels distinguish between the sites of tetraethylammonium blockade and C-type inactivation. J. Physiol. 499:361-367.
-
(1997)
J. Physiol.
, vol.499
, pp. 361-367
-
-
Molina, A.1
Castellano, A.G.2
Lopez-Barneo, J.3
-
36
-
-
0038277048
-
Different binding orientations for the same agonist at homologous receptors: A lock and key or a simple wedge?
-
Mu, T.W., H.A. Lester, and D.A. Dougherty. 2003. Different binding orientations for the same agonist at homologous receptors: a lock and key or a simple wedge? J. Am. Chem. Soc. 125:6850-6851.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 6850-6851
-
-
Mu, T.W.1
Lester, H.A.2
Dougherty, D.A.3
-
37
-
-
0029005830
-
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells
-
Nowak, M.W., P.C. Kearney, J.R. Sampson, M.E. Saks, C.G. Labarca, S.K. Silverman, W. Zhong, J. Thorson, J.N. Abelson, N. Davidson, et al. 1995. Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells. Science. 268:439-442.
-
(1995)
Science
, vol.268
, pp. 439-442
-
-
Nowak, M.W.1
Kearney, P.C.2
Sampson, J.R.3
Saks, M.E.4
Labarca, C.G.5
Silverman, S.K.6
Zhong, W.7
Thorson, J.8
Abelson, J.N.9
Davidson, N.10
-
38
-
-
0032311418
-
In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system
-
Nowak, M.W., J.P. Gallivan, S.K. Silverman, C.G. Labarca, D.A. Dougherty, and H.A. Lester. 1998. In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system. Methods Enzymol. 293:504-529.
-
(1998)
Methods Enzymol.
, vol.293
, pp. 504-529
-
-
Nowak, M.W.1
Gallivan, J.P.2
Silverman, S.K.3
Labarca, C.G.4
Dougherty, D.A.5
Lester, H.A.6
-
39
-
-
0024286073
-
Influences of solvent water on protein folding: Free energies of solvation of cis and trans peptides are nearly identical
-
Radzicka, A., L. Pedersen, and R. Wolfenden. 1988. Influences of solvent water on protein folding: free energies of solvation of cis and trans peptides are nearly identical. Biochemistry. 27:4538-4541.
-
(1988)
Biochemistry
, vol.27
, pp. 4538-4541
-
-
Radzicka, A.1
Pedersen, L.2
Wolfenden, R.3
-
40
-
-
2142775205
-
Molecular recognition in aqueous media: Donor-acceptor and ion-dipole interactions produce tight binding for highly soluble guests
-
Shepodd, T.J., M.A. Petti, and D.A. Dougherty. 1988. Molecular recognition in aqueous media: donor-acceptor and ion-dipole interactions produce tight binding for highly soluble guests. J. Amer. Chem. Soc. 110:1983-1985.
-
(1988)
J. Amer. Chem. Soc.
, vol.110
, pp. 1983-1985
-
-
Shepodd, T.J.1
Petti, M.A.2
Dougherty, D.A.3
-
41
-
-
30244527819
-
How does basis set superposition error change the potential surfaces for hydrogen-bonded dimers?
-
Simon, S., M. Duran, and J.J. Dannenberg. 1996. How does basis set superposition error change the potential surfaces for hydrogen-bonded dimers? J. Chem. Phys. 105:11024-11031.
-
(1996)
J. Chem. Phys.
, vol.105
, pp. 11024-11031
-
-
Simon, S.1
Duran, M.2
Dannenberg, J.J.3
-
43
-
-
0023607711
-
The action of external tetraethylammonium ions on unitary delayed rectifier potassium channels of frog skeletal muscle
-
Spruce, A.E., N.B. Standen, and P.R. Stanfield. 1987. The action of external tetraethylammonium ions on unitary delayed rectifier potassium channels of frog skeletal muscle. J. Physiol. 393:467-478.
-
(1987)
J. Physiol.
, vol.393
, pp. 467-478
-
-
Spruce, A.E.1
Standen, N.B.2
Stanfield, P.R.3
-
44
-
-
0024449639
-
Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain
-
Stuhmer, W., J.P. Ruppersberg, K.H. Schroter, B. Sakmann, M. Stocker, K.P. Giese, A. Perschke, A. Baumann, and O. Pongs. 1989. Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain. EMBO J. 8:3235-3244.
-
(1989)
EMBO J.
, vol.8
, pp. 3235-3244
-
-
Stuhmer, W.1
Ruppersberg, J.P.2
Schroter, K.H.3
Sakmann, B.4
Stocker, M.5
Giese, K.P.6
Perschke, A.7
Baumann, A.8
Pongs, O.9
-
45
-
-
0042360510
-
+ channels is coupled to the movement of K+ ions within the selectivity filter
-
+ channels is coupled to the movement of K+ ions within the selectivity filter. J. Gen. Physiol. 122:239-246.
-
(2003)
J. Gen. Physiol.
, vol.122
, pp. 239-246
-
-
Thompson, J.1
Begenisich, T.2
-
46
-
-
0000491257
-
The molecular electric quadrupole moment and solid-state architecture
-
Williams, J.H. 1993. The molecular electric quadrupole moment and solid-state architecture. Accounts Chem. Res. 26:593-598.
-
(1993)
Accounts Chem. Res.
, vol.26
, pp. 593-598
-
-
Williams, J.H.1
-
47
-
-
28544434796
-
Nuclear magnetic resonance structural studies of a potassium channel-charybdotoxin complex
-
Yu, L., C. Sun, D. Song, J. Shen, N. Xu, A. Gunasekera, P.J. Hajduk, and E.T. Olejniczak. 2005. Nuclear magnetic resonance structural studies of a potassium channel-charybdotoxin complex. Biochemistry. 44:15834-15841.
-
(2005)
Biochemistry
, vol.44
, pp. 15834-15841
-
-
Yu, L.1
Sun, C.2
Song, D.3
Shen, J.4
Xu, N.5
Gunasekera, A.6
Hajduk, P.J.7
Olejniczak, E.T.8
-
48
-
-
0032514762
-
From ab initio quantum mechanics to molecular neurobiology: A cation-π binding site in the nicotinic receptor
-
Zhong, W., J.P. Gallivan, Y. Zhang, L. Li, H.A. Lester, and D.A. Dougherty. 1998. From ab initio quantum mechanics to molecular neurobiology: a cation-π binding site in the nicotinic receptor. Proc. Natl. Acad. Sci. USA. 95:12088-12093.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12088-12093
-
-
Zhong, W.1
Gallivan, J.P.2
Zhang, Y.3
Li, L.4
Lester, H.A.5
Dougherty, D.A.6
-
49
-
-
0142185496
-
The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
-
Zhou, Y., and R. MacKinnon. 2003. The occupancy of ions in the K+ selectivity filter: charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates. J. Mol. Biol. 333:965-975.
-
(2003)
J. Mol. Biol.
, vol.333
, pp. 965-975
-
-
Zhou, Y.1
MacKinnon, R.2
|