Multiple tyrosine residues contribute to GABA Binding in the GABA C receptor binding pocket

ACS Chemical Neuroscience

Volumn 3, Issue 3, 2012, Pages 186-192

  Lummis, Sarah C R ^a   Harrison, Neil J ^a   Wang, Jinti ^b   Ashby, Jamie A ^a   Millen, Katherine S ^a   Beene, Darren L ^b   Dougherty, Dennis A ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b California Institute of Technology   (United States)

Author keywords

interaction; binding site; cation interaction; Cys loop receptor; unnatural amino acid mutagenesis

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID C RECEPTOR; ARGININE; HYDROXYL GROUP; TYROSINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HYDROGEN BOND; INFORMATION PROCESSING; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; SENSITIVITY ANALYSIS;

EID: 84863338048     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn200103n     Document Type: Article

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