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Volumn 4, Issue 11, 2012, Pages

Targeting Wnt pathways in disease

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; APC PROTEIN, HUMAN; BETA CATENIN; CELL RECEPTOR; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 84868537782     PISSN: None     EISSN: 19430264     Source Type: Journal    
DOI: 10.1101/cshperspect.a008086     Document Type: Article
Times cited : (89)

References (207)
  • 1
    • 77956822573 scopus 로고    scopus 로고
    • Sclerostin antibody treatment enhances metaphyseal bone healing in rats
    • Agholme F, Li X, Isaksson H, Ke HZ, Aspenberg P. 2010. Sclerostin antibody treatment enhances metaphyseal bone healing in rats. J Bone Miner Res 25: 2412-2418.
    • (2010) J Bone Miner Res , vol.25 , pp. 2412-2418
    • Agholme, F.1    Li, X.2    Isaksson, H.3    Ke, H.Z.4    Aspenberg, P.5
  • 2
    • 29344459785 scopus 로고    scopus 로고
    • Importance of P-cadherin, β-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma
    • Bachmann IM, Straume O, Puntervoll HE, Kalvenes MB, Akslen LA. 2005. Importance of P-cadherin, β-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma. Clin Cance Res 11: 8606-8614.
    • (2005) Clin Cance Res , vol.11 , pp. 8606-8614
    • Bachmann, I.M.1    Straume, O.2    Puntervoll, H.E.3    Kalvenes, M.B.4    Akslen, L.A.5
  • 3
    • 35748984680 scopus 로고    scopus 로고
    • Generation of multipotential mesendodermal progenitors from mouse embryonic stem cells via sustaine Wnt pathway activation
    • Bakre MM, Hoi A, Mong JC, Koh YY, Wong KY, Stanton LW. 2007. Generation of multipotential mesendodermal progenitors from mouse embryonic stem cells via sustaine Wnt pathway activation. J Biol Chem 282: 31703-31712.
    • (2007) J Biol Chem , vol.282 , pp. 31703-31712
    • Bakre, M.M.1    Hoi, A.2    Mong, J.C.3    Koh, Y.Y.4    Wong, K.Y.5    Stanton, L.W.6
  • 4
    • 58749086442 scopus 로고    scopus 로고
    • Assaying β-catenin/TCF transcription with β-catenin/TCF transcription-based reporter constructs
    • Humana Press, Clifton, NJ
    • Biechele TL, Moon RT. 2008. Assaying β-catenin/TCF transcription with β-catenin/TCF transcription-based reporter constructs. Methods in molecular biology, Vol. 468, pp. 99-110. Humana Press, Clifton, NJ.
    • (2008) Methods in molecular biology , vol.468 , pp. 99-110
    • Biechele, T.L.1    Moon, R.T.2
  • 6
    • 0034927864 scopus 로고    scopus 로고
    • Schizophrenia and affective disorders-Cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family
    • Blackwood DHR, Fordyce A, Walker MT, St. Clair DM, Porteou DJ, Muir WJ. 2001. Schizophrenia and affective disorders-Cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family. Am J Hum Genet 69: 428-433.
    • (2001) Am J Hum Genet , vol.69 , pp. 428-433
    • Blackwood, D.H.R.1    Fordyce, A.2    Walker, M.T.3    St. Clair, D.M.4    Porteou, D.J.5    Muir, W.J.6
  • 8
    • 0842329914 scopus 로고    scopus 로고
    • Sulindac targets nuclear β-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines
    • Boon EM. J, Keller JJ, Wormhoudt TA. M, Giardiello FM, Offerhaus GJ. A, van der Neut R, Pals ST. 2004. Sulindac targets nuclear β-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines. Brit J Cancer 90: 224-229.
    • (2004) Brit J Cancer , vol.90 , pp. 224-229
    • Boon, E.M.J.1    Keller, J.J.2    Wormhoudt, T.A.M.3    Giardiello, F.M.4    Offerhaus, G.J.A.5    van der Neut, R.6    Pals, S.T.7
  • 11
    • 47249149740 scopus 로고    scopus 로고
    • Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases
    • Bu G, Lu W, Liu C-C, Selander K, Yoneda T, Hall C, Kelle ET, Li Y. 2008. Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases. Int J Cancer 123: 1034-1042.
    • (2008) Int J Cancer , vol.123 , pp. 1034-1042
    • Bu, G.1    Lu, W.2    Liu, C-C.3    Selander, K.4    Yoneda, T.5    Hall, C.6    Kelle, E.T.7    Li, Y.8
  • 13
    • 72049111230 scopus 로고    scopus 로고
    • The planar cell polarity protein Van Gogh-Like 2 regulates tumor cell migration and matrix metalloproteinase-dependent invasion
    • Cantrell VA, Jessen JR. 2010. The planar cell polarity protein Van Gogh-Like 2 regulates tumor cell migration and matrix metalloproteinase-dependent invasion. Cancer Lett 287: 54-61.
    • (2010) Cancer Lett , vol.287 , pp. 54-61
    • Cantrell, V.A.1    Jessen, J.R.2
  • 16
    • 34249781154 scopus 로고    scopus 로고
    • Human immunodeficiency virus-restricted replication in astrocytes and the ability of γ interferon to modulate this restriction are regulated by a downstream effector of the Wnt signaling pathway
    • Carroll-Anzinger D, Kumar A, Adarichev V, Kashanchi F, Al-Harthi L. 2007. Human immunodeficiency virus-restricted replication in astrocytes and the ability of γ interferon to modulate this restriction are regulated by a downstream effector of the Wnt signaling pathway. J Virol 81: 5864-5871.
    • (2007) J Virol , vol.81 , pp. 5864-5871
    • Carroll-Anzinger, D.1    Kumar, A.2    Adarichev, V.3    Kashanchi, F.4    Al-Harthi, L.5
  • 17
    • 0037114729 scopus 로고    scopus 로고
    • A survival-stratification model of human colorectal carcinomas with β-catenin and 27kip1
    • Cheah PY, Choo PH, Yao J, Eu KW, Seow-Choen F. 2002. A survival-stratification model of human colorectal carcinomas with β-catenin and 27kip1. Cancer 95: 2479-2486.
    • (2002) Cancer , vol.95 , pp. 2479-2486
    • Cheah, P.Y.1    Choo, P.H.2    Yao, J.3    Eu, K.W.4    Seow-Choen, F.5
  • 19
    • 67449150167 scopus 로고    scopus 로고
    • A Wnt survival guide: Fromflies to human disease
    • Chien AJ, Conrad WH, Moon RT. 2009a. A Wnt survival guide: Fromflies to human disease. J Invest Dermatol 129: 1614-1627.
    • (2009) J Invest Dermatol , vol.129 , pp. 1614-1627
    • Chien, A.J.1    Conrad, W.H.2    Moon, R.T.3
  • 24
    • 17844372752 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
    • Day TF, Guo X, Garrett-Beal L, Yang Y. 2005. Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev Cell 8: 739-750.
    • (2005) Dev Cell , vol.8 , pp. 739-750
    • Day, T.F.1    Guo, X.2    Garrett-Beal, L.3    Yang, Y.4
  • 25
    • 34347254641 scopus 로고    scopus 로고
    • The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
    • DeAlmeida VI, Miao L, Ernst JA, Koeppen H, Polakis P, Rubinfeld B. 2007. The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo. Cancer Res 67: 5371-5379.
    • (2007) Cancer Res , vol.67 , pp. 5371-5379
    • DeAlmeida, V.I.1    Miao, L.2    Ernst, J.A.3    Koeppen, H.4    Polakis, P.5    Rubinfeld, B.6
  • 27
    • 33845350346 scopus 로고    scopus 로고
    • The ups and downs of Wnt signaling in prevalent neurological disorders
    • De Ferrari GV, Moon RT. 2006. The ups and downs of Wnt signaling in prevalent neurological disorders. Oncogene 25: 7545-7553.
    • (2006) Oncogene , vol.25 , pp. 7545-7553
    • De Ferrari, G.V.1    Moon, R.T.2
  • 30
    • 38949168084 scopus 로고    scopus 로고
    • β-Catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells
    • Ding Y, Shen S, Lino AC, Curotto de Lafaille MA, Lafaille JJ. 2008. β-Catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells. Nat Med 14: 162-169.
    • (2008) Nat Med , vol.14 , pp. 162-169
    • Ding, Y.1    Shen, S.2    Lino, A.C.3    Curotto de Lafaille, M.A.4    Lafaille, J.J.5
  • 31
    • 0034650485 scopus 로고    scopus 로고
    • Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway
    • Dorsky RI, Raible DW, Moon RT. 2000. Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway. Genes Dev 14: 158-162.
    • (2000) Genes Dev , vol.14 , pp. 158-162
    • Dorsky, R.I.1    Raible, D.W.2    Moon, R.T.3
  • 35
    • 3242766018 scopus 로고    scopus 로고
    • Substituted 3-imidazo[1,2-a]pyridin-3-yl-4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3
    • Engler TA, Henry JR, Malhotra S, Cunningham B, Furness K, Brozinick J, Burkholder TP, Clay MP, Clayton J, Diefenbache C, et al. 2004. Substituted 3-imidazo[1,2-a]pyridin-3-yl-4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3. J Me Chem 47: 3934-3937.
    • (2004) J Me Chem , vol.47 , pp. 3934-3937
    • Engler, T.A.1    Henry, J.R.2    Malhotra, S.3    Cunningham, B.4    Furness, K.5    Brozinick, J.6    Burkholder, T.P.7    Clay, M.P.8    Clayton, J.9    Diefenbache, C.10
  • 37
    • 67649319056 scopus 로고    scopus 로고
    • The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERα negative breast cancer
    • Ford CE, Ekström EJ, Howlin J, Andersson T. 2009. The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERα negative breast cancer. Cell Cycle (Georgetown, Tex) 8: 1838-1842.
    • (2009) Cell Cycle (Georgetown, Tex) , vol.8 , pp. 1838-1842
    • Ford, C.E.1    Ekström, E.J.2    Howlin, J.3    Andersson, T.4
  • 38
    • 77950598371 scopus 로고    scopus 로고
    • Roles of the Akt/ GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action
    • Freyberg Z, Ferrando SJ, Javitch JA. 2010. Roles of the Akt/ GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action. Am J Psychiat 167: 388-396.
    • (2010) Am J Psychiat , vol.167 , pp. 388-396
    • Freyberg, Z.1    Ferrando, S.J.2    Javitch, J.A.3
  • 39
    • 30544447981 scopus 로고    scopus 로고
    • Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-smallcell lung cancer
    • Fukui T, Kondo M, Ito G, Maeda O, Sato N, Yoshioka H, Yokoi K, Ueda Y, Shimokata K, Sekido Y. 2005. Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-smallcell lung cancer. Oncogene 24: 6323-6327.
    • (2005) Oncogene , vol.24 , pp. 6323-6327
    • Fukui, T.1    Kondo, M.2    Ito, G.3    Maeda, O.4    Sato, N.5    Yoshioka, H.6    Yokoi, K.7    Ueda, Y.8    Shimokata, K.9    Sekido, Y.10
  • 42
    • 0032813907 scopus 로고    scopus 로고
    • β-Catenin expression pattern in stage I and II ovarian carcinomas: Relationship with β-catenin gene mutations, clinicopathological features, and clinical outcome
    • Gamallo C, Palacios J, Moreno G, Calvo deMora J, Suárez A, Armas A. 1999. β-Catenin expression pattern in stage I and II ovarian carcinomas: Relationship with β-catenin gene mutations, clinicopathological features, and clinical outcome. Am J Pathol 155: 527-536.
    • (1999) Am J Pathol , vol.155 , pp. 527-536
    • Gamallo, C.1    Palacios, J.2    Moreno, G.3    de Calvo Mora, J.4    Suárez, A.5    Armas, A.6
  • 46
    • 78650040987 scopus 로고    scopus 로고
    • Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo
    • Glantschnig H, Hampton RA, Lu P, Zhao JZ, Vitelli S, Huang L, Haytko P, Cusick T, Ireland C, Jarantow SW, et al. 2010. Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo. J Biol Chem 285: 40135-40147.
    • (2010) J Biol Chem , vol.285 , pp. 40135-40147
    • Glantschnig, H.1    Hampton, R.A.2    Lu, P.3    Zhao, J.Z.4    Vitelli, S.5    Huang, L.6    Haytko, P.7    Cusick, T.8    Ireland, C.9    Jarantow, S.W.10
  • 50
    • 7244229604 scopus 로고    scopus 로고
    • Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes
    • Gottardi CJ, Gumbiner BM. 2004. Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes. J Cell Biol 167: 339-349.
    • (2004) J Cell Biol , vol.167 , pp. 339-349
    • Gottardi, C.J.1    Gumbiner, B.M.2
  • 51
    • 0033635606 scopus 로고    scopus 로고
    • Crystal structure of a β-catenin/Tcf complex
    • Graham TA, Weaver C, Mao F, Kimelman D, Xu W. 2000. Crystal structure of a β-catenin/Tcf complex. Cell 103: 885-896.
    • (2000) Cell , vol.103 , pp. 885-896
    • Graham, T.A.1    Weaver, C.2    Mao, F.3    Kimelman, D.4    Xu, W.5
  • 53
    • 83255171058 scopus 로고    scopus 로고
    • Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease
    • Guettler S, Larose J, Petsalaki E, Gish G, Scotter A, Pawson T, Rottapel R, Sicheri F. 2011. Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell 147: 1340-1354.
    • (2011) Cell , vol.147 , pp. 1340-1354
    • Guettler, S.1    Larose, J.2    Petsalaki, E.3    Gish, G.4    Scotter, A.5    Pawson, T.6    Rottapel, R.7    Sicheri, F.8
  • 54
    • 79551617573 scopus 로고    scopus 로고
    • Pharmaceutical inhibition of glycogen-synthetase-kinase-3-β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model
    • Gunn WG, Krause U, Lee N, Gregory CA. 2010. Pharmaceutical inhibition of glycogen-synthetase-kinase-3-β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model. Blood 117: 1641-1651.
    • (2010) Blood , vol.117 , pp. 1641-1651
    • Gunn, W.G.1    Krause, U.2    Lee, N.3    Gregory, C.A.4
  • 57
    • 18344377028 scopus 로고    scopus 로고
    • Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations
    • He B, Reguart N, You L, Mazieres J, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM. 2005b. Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations. Oncogene 24: 3054-3058.
    • (2005) Oncogene , vol.24 , pp. 3054-3058
    • He, B.1    Reguart, N.2    You, L.3    Mazieres, J.4    Xu, Z.5    Lee, A.Y.6    Mikami, I.7    McCormick, F.8    Jablons, D.M.9
  • 62
    • 0035110947 scopus 로고    scopus 로고
    • Transcription factors in melanocyte development: Distinct roles for Pax-3 and Mitf
    • Hornyak TJ, Hayes DJ, Chiu LY, Ziff EB. 2001. Transcription factors in melanocyte development: Distinct roles for Pax-3 and Mitf. Mech Dev 101: 47-59.
    • (2001) Mech Dev , vol.101 , pp. 47-59
    • Hornyak, T.J.1    Hayes, D.J.2    Chiu, L.Y.3    Ziff, E.B.4
  • 65
    • 0035805117 scopus 로고    scopus 로고
    • The structure of the β-catenin/ E-cadherin complex and the molecular basis of diverse ligand recognition by β-catenin
    • Huber AH, Weis WI. 2001. The structure of the β-catenin/ E-cadherin complex and the molecular basis of diverse ligand recognition by β-catenin. Cell 105: 391-402.
    • (2001) Cell , vol.105 , pp. 391-402
    • Huber, A.H.1    Weis, W.I.2
  • 67
    • 77953107073 scopus 로고    scopus 로고
    • Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory
    • Jeannet G, Boudousquié C, Gardiol N, Kang J, Huelsken J, HeldW. 2010. Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory. Proc Natl Acad Sci 107: 9777-9782.
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 9777-9782
    • Jeannet, G.1    Boudousquié, C.2    Gardiol, N.3    Kang, J.4    Huelsken, J.5    Held, W.6
  • 69
    • 0034799321 scopus 로고    scopus 로고
    • Loss of β-catenin expression associated with disease progression in malignant melanoma
    • Kageshita T, Hamby CV, Ishihara T, Matsumoto K, Saida T, Ono T. 2001. Loss of β-catenin expression associated with disease progression in malignant melanoma. Brit J Dermatol 145: 210-216.
    • (2001) Brit J Dermatol , vol.145 , pp. 210-216
    • Kageshita, T.1    Hamby, C.V.2    Ishihara, T.3    Matsumoto, K.4    Saida, T.5    Ono, T.6
  • 70
    • 70449505308 scopus 로고    scopus 로고
    • Short communication: RNA interference directed against Axin1 upregulates human immunodeficiency virus type 1 gene expression by activating the Wnt signaling pathway in HeLa-derive J111 cells
    • Kameoka M, Kameoka Y, Utachee P, Kurosu T, Sawanpanyaler P, Ikuta K, Auwanit W. 2009. Short communication: RNA interference directed against Axin1 upregulates human immunodeficiency virus type 1 gene expression by activating the Wnt signaling pathway in HeLa-derive J111 cells. AIDS Res Hum Retroviruses 25: 1005-1011.
    • (2009) AIDS Res Hum Retroviruses , vol.25 , pp. 1005-1011
    • Kameoka, M.1    Kameoka, Y.2    Utachee, P.3    Kurosu, T.4    Sawanpanyaler, P.5    Ikuta, K.6    Auwanit, W.7
  • 71
    • 0037145062 scopus 로고    scopus 로고
    • Presenilin couples the paired phosphorylation of β-catenin independent of axin: Implications for β-catenin activation in tumorigenesis
    • Kang DE, Soriano S, Xia X, Eberhart CG, De Strooper B, Zheng H, Koo EH. 2002. Presenilin couples the paired phosphorylation of β-catenin independent of axin: Implications for β-catenin activation in tumorigenesis. Cell 110: 751-762.
    • (2002) Cell , vol.110 , pp. 751-762
    • Kang, D.E.1    Soriano, S.2    Xia, X.3    Eberhart, C.G.4    de Strooper, B.5    Zheng, H.6    Koo, E.H.7
  • 72
    • 0036652933 scopus 로고    scopus 로고
    • Strabismus (STB)/Vang-like (VANGL) gene family (Review)
    • Katoh M. 2002. Strabismus (STB)/Vang-like (VANGL) gene family (Review). Int J Mol Med 10: 11-15.
    • (2002) Int J Mol Med , vol.10 , pp. 11-15
    • Katoh, M.1
  • 74
    • 60049091422 scopus 로고    scopus 로고
    • KITENIN recruits Dishevelled/ PKCd to form a functional complex and controls the migration and invasiveness of colorectal cancer cells
    • Kho DH, Bae JA, Lee JH, Cho HJ, Cho SH, Seo Y-W, Ahn KY, Chung IJ, Kim KK. 2009. KITENIN recruits Dishevelled/ PKCd to form a functional complex and controls the migration and invasiveness of colorectal cancer cells. Gut 58: 509-519.
    • (2009) Gut , vol.58 , pp. 509-519
    • Kho, D.H.1    Bae, J.A.2    Lee, J.H.3    Cho, H.J.4    Cho, S.H.5    Seo, Y-W.6    Ahn, K.Y.7    Chung, I.J.8    Kim, K.K.9
  • 77
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein PS, Melton DA. 1996. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci 93: 8455-8459.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 81
    • 40149101557 scopus 로고    scopus 로고
    • Active β-catenin signaling is an inhibitory path-way for human immunodeficiency virus replication in peripheral blood mononuclear cells
    • Kumar A, Zloza A, Moon RT, Watts J, Tenorio AR, Al-Harth L. 2008. Active β-catenin signaling is an inhibitory path-way for human immunodeficiency virus replication in peripheral blood mononuclear cells. J Virol 82: 2813-2820.
    • (2008) J Virol , vol.82 , pp. 2813-2820
    • Kumar, A.1    Zloza, A.2    Moon, R.T.3    Watts, J.4    Tenorio, A.R.5    Al-Harth, L.6
  • 82
    • 33751295132 scopus 로고    scopus 로고
    • Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion
    • Kurayoshi M, Oue N, Yamamoto H, Kishida M, Inoue A, Asahara T, Yasui W, Kikuchi A. 2006. Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion. Cancer Res 66: 10439-10448.
    • (2006) Cancer Res , vol.66 , pp. 10439-10448
    • Kurayoshi, M.1    Oue, N.2    Yamamoto, H.3    Kishida, M.4    Inoue, A.5    Asahara, T.6    Yasui, W.7    Kikuchi, A.8
  • 87
    • 3042659106 scopus 로고    scopus 로고
    • KAI1 COOH-terminal interacting tetraspanin (KITENIN), a member of the tetraspanin family, interacts with KAI1, a tumor metastasis suppressor, and enhances metastasis of cancer
    • Lee JH, Park SR, Chay K-O, Seo Y-W, Kook H, Ahn KY, Ki YJ, Kim KK. 2004b. KAI1 COOH-terminal interacting tetraspanin (KITENIN), a member of the tetraspanin family, interacts with KAI1, a tumor metastasis suppressor, and enhances metastasis of cancer. Cancer Res 64: 4235-4243.
    • (2004) Cancer Res , vol.64 , pp. 4235-4243
    • Lee, J.H.1    Park, S.R.2    Chay, K-O.3    Seo, Y-W.4    Kook, H.5    Ahn, K.Y.6    Ki, Y.J.7    Kim, K.K.8
  • 88
    • 60049089355 scopus 로고    scopus 로고
    • KITENIN increases invasion and migration of mouse squamous cancer cells and promotes pulmonary metastasis in a mouse squamous tumor model
    • Lee JK, Bae JA, Sun EG, Kim HD, Yoon TM, Kim K, Lee JH, Lim SC, Kim KK. 2009. KITENIN increases invasion and migration of mouse squamous cancer cells and promotes pulmonary metastasis in a mouse squamous tumor model. FEBS Lett 583: 711-717.
    • (2009) FEBS Lett , vol.583 , pp. 711-717
    • Lee, J.K.1    Bae, J.A.2    Sun, E.G.3    Kim, H.D.4    Yoon, T.M.5    Kim, K.6    Lee, J.H.7    Lim, S.C.8    Kim, K.K.9
  • 89
    • 80054944137 scopus 로고    scopus 로고
    • Persicaria hydropiper (L.) spach and its flavonoid components, isoquercitrin and isorhamnetin, activate the Wnt/β-catenin pathway and inhibit adipocyte differentiation of 3T3-L1 cells
    • Lee S-H, Kim B, Oh MJ, Yoon J, Kim HY, Lee KJ, Lee JD, Choi K-Y. 2011. Persicaria hydropiper (L.) spach and its flavonoid components, isoquercitrin and isorhamnetin, activate the Wnt/β-catenin pathway and inhibit adipocyte differentiation of 3T3-L1 cells. Phytother Res 25: 1629-1635.
    • (2011) Phytother Res , vol.25 , pp. 1629-1635
    • Lee, S-H.1    Kim, B.2    Oh, M.J.3    Yoon, J.4    Kim, H.Y.5    Lee, K.J.6    Lee, J.D.7    Choi, K-Y.8
  • 97
    • 33847324442 scopus 로고    scopus 로고
    • Prognostic significance of thewnt signalling pathway molecules APC, β-catenin and E-cadherin in colorectal cancer: A tissue microarray-based analysis
    • Lugli A, Zlobec I, Minoo P, Baker K, Tornillo L, Terraccian L, Jass JR. 2007. Prognostic significance of thewnt signalling pathway molecules APC, β-catenin and E-cadherin in colorectal cancer: A tissue microarray-based analysis. Histopathology 50: 453-464.
    • (2007) Histopathology , vol.50 , pp. 453-464
    • Lugli, A.1    Zlobec, I.2    Minoo, P.3    Baker, K.4    Tornillo, L.5    Terraccian, L.6    Jass, J.R.7
  • 98
    • 0042835743 scopus 로고    scopus 로고
    • Reduced β-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma
    • Maelandsmo GM, Holm R, Nesland JM, Fodstad Ø, Flørene VA. 2003. Reduced β-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma. Clin Cancer Res 9: 3383-3388.
    • (2003) Clin Cancer Res , vol.9 , pp. 3383-3388
    • Maelandsmo, G.M.1    Holm, R.2    Nesland, J.M.3    Fodstad, O.4    Flørene, V.A.5
  • 103
    • 62149083806 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3b/β-catenin signaling
    • Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Dou MK, Tassa C, Berry EM, Soda T, Singh KK, et al. 2009. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3b/β-catenin signaling. Cell 136: 1017-1031.
    • (2009) Cell , vol.136 , pp. 1017-1031
    • Mao, Y.1    Ge, X.2    Frank, C.L.3    Madison, J.M.4    Koehler, A.N.5    Dou, M.K.6    Tassa, C.7    Berry, E.M.8    Soda, T.9    Singh, K.K.10
  • 105
    • 24044490922 scopus 로고    scopus 로고
    • Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis
    • Mazieres J, You L, He B, Xu Z, Lee AY, Mikami I, McCormic F, Jablons DM. 2005a. Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. Oncogene 24: 5396-5400.
    • (2005) Oncogene , vol.24 , pp. 5396-5400
    • Mazieres, J.1    You, L.2    He, B.3    Xu, Z.4    Lee, A.Y.5    Mikami, I.6    McCormic, F.7    Jablons, D.M.8
  • 108
    • 16644366891 scopus 로고    scopus 로고
    • Expression of Wnt genes and frizzled 1 and 2 receptors in normal breast epithelium and infiltrating breast carcinoma
    • Milovanovic T, Planutis K, Nguyen A, Marsh JL, Lin F, Hop C, Holcombe RF. 2004. Expression of Wnt genes and frizzled 1 and 2 receptors in normal breast epithelium and infiltrating breast carcinoma. Int J Oncol 25: 1337-1342.
    • (2004) Int J Oncol , vol.25 , pp. 1337-1342
    • Milovanovic, T.1    Planutis, K.2    Nguyen, A.3    Marsh, J.L.4    Lin, F.5    Hop, C.6    Holcombe, R.F.7
  • 111
    • 0033609561 scopus 로고    scopus 로고
    • Increased expression of Wnt-1 in schizophrenic brains
    • Miyaoka T, Seno H, Ishino H. 1999. Increased expression of Wnt-1 in schizophrenic brains. Schizophr Res 38: 1-6.
    • (1999) Schizophr Res , vol.38 , pp. 1-6
    • Miyaoka, T.1    Seno, H.2    Ishino, H.3
  • 112
    • 59449102727 scopus 로고    scopus 로고
    • Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides
    • Moore WJ, Kern JC, Bhat R, Commons TJ, Fukayama S, Goljer I, Krishnamurthy G, Magolda RL, Nogle L, Pitt K, et al. 2009. Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides. J Med Chem 52: 105-116.
    • (2009) J Med Chem , vol.52 , pp. 105-116
    • Moore, W.J.1    Kern, J.C.2    Bhat, R.3    Commons, T.J.4    Fukayama, S.5    Goljer, I.6    Krishnamurthy, G.7    Magolda, R.L.8    Nogle, L.9    Pitt, K.10
  • 113
    • 76649105065 scopus 로고    scopus 로고
    • β-Catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
    • Morris JP IV, Cano DA, Sekine S, Wang SC, Hebrok M. β-Catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice. J Clin Invest 120: 508-520.
    • J Clin Invest , vol.120 , pp. 508-520
    • Morris IV, J.P.1    Cano, D.A.2    Sekine, S.3    Wang, S.C.4    Hebrok, M.5
  • 114
    • 0035879075 scopus 로고    scopus 로고
    • Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogenactivated protein kinase and c-Jun terminal kinase
    • Mudher A, Chapman S, Richardson J, Asuni A, Gibb G, Pollard C, Killick R, Iqbal T, Raymond L, Varndell I, et al. 2001. Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogenactivated protein kinase and c-Jun terminal kinase. JNeurosci 21: 4987-4995.
    • (2001) JNeurosci , vol.21 , pp. 4987-4995
    • Mudher, A.1    Chapman, S.2    Richardson, J.3    Asuni, A.4    Gibb, G.5    Pollard, C.6    Killick, R.7    Iqbal, T.8    Raymond, L.9    Varndell, I.10
  • 116
    • 21244440341 scopus 로고    scopus 로고
    • Expression profiles and functional analyses of Wnt-related genes in human joint disorders
    • Nakamura Y, Nawata M, Wakitani S. 2005. Expression profiles and functional analyses of Wnt-related genes in human joint disorders. Am J Pathol 167: 97-105.
    • (2005) Am J Pathol , vol.167 , pp. 97-105
    • Nakamura, Y.1    Nawata, M.2    Wakitani, S.3
  • 119
    • 37549020639 scopus 로고    scopus 로고
    • Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood
    • Nostro MC, Cheng X, Keller GM, Gadue P. 2008. Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood. Cell Stem Cell 2: 60-71.
    • (2008) Cell Stem Cell , vol.2 , pp. 60-71
    • Nostro, M.C.1    Cheng, X.2    Keller, G.M.3    Gadue, P.4
  • 121
    • 43049144313 scopus 로고    scopus 로고
    • Wnt signaling and stem cell control
    • Nusse R. 2008. Wnt signaling and stem cell control. Cell Res 18: 523-527.
    • (2008) Cell Res , vol.18 , pp. 523-527
    • Nusse, R.1
  • 122
    • 0020216124 scopus 로고
    • Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
    • Nusse R, Varmus HE. 1982. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell 31: 99-109.
    • (1982) Cell , vol.31 , pp. 99-109
    • Nusse, R.1    Varmus, H.E.2
  • 123
    • 2142746966 scopus 로고    scopus 로고
    • Up-regulation and overproduction of DVL-1, the human counterpart of the Drosophila dishevelled gene, in cervical squamous cell carcinoma
    • Okino K, Nagai H, Hatta M, Nagahata T, Yoneyama K, Oht Y, Jin E, Kawanami O, Araki T, Emi M. 2003. Up-regulation and overproduction of DVL-1, the human counterpart of the Drosophila dishevelled gene, in cervical squamous cell carcinoma. Oncol Rep 10: 1219-1223.
    • (2003) Oncol Rep , vol.10 , pp. 1219-1223
    • Okino, K.1    Nagai, H.2    Hatta, M.3    Nagahata, T.4    Yoneyama, K.5    Oht, Y.6    Jin, E.7    Kawanami, O.8    Araki, T.9    Emi, M.10
  • 125
    • 78650958526 scopus 로고    scopus 로고
    • Singledose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
    • Padhi D, Jang G, Stouch B, Fang L, Posvar E. 2011. Singledose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody. J Bone Miner Res 26: 19-26.
    • (2011) J Bone Miner Res , vol.26 , pp. 19-26
    • Padhi, D.1    Jang, G.2    Stouch, B.3    Fang, L.4    Posvar, E.5
  • 126
    • 77955290927 scopus 로고    scopus 로고
    • Endogenous Wnt/β-catenin signaling is required for cardiac differentiation in human embryonic stem cells
    • Paige SL, Osugi T, Afanasiev OK, Pabon L, Reinecke H, Murry CE. 2010. Endogenous Wnt/β-catenin signaling is required for cardiac differentiation in human embryonic stem cells. PloS ONE 5: e11134.
    • (2010) PloS ONE , vol.5
    • Paige, S.L.1    Osugi, T.2    Afanasiev, O.K.3    Pabon, L.4    Reinecke, H.5    Murry, C.E.6
  • 129
    • 0036114348 scopus 로고    scopus 로고
    • A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis
    • Phillips RKS, Wallace MH, Lynch PM, Hawk E, Gordon GB, Saunders BP, Wakabayashi N, Shen Y, Zimmerman S, Godio L, et al. 2002. A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis. Gut 50: 857-860.
    • (2002) Gut , vol.50 , pp. 857-860
    • Phillips, R.K.S.1    Wallace, M.H.2    Lynch, P.M.3    Hawk, E.4    Gordon, G.B.5    Saunders, B.P.6    Wakabayashi, N.7    Shen, Y.8    Zimmerman, S.9    Godio, L.10
  • 131
    • 33645774667 scopus 로고    scopus 로고
    • Wnt 5α signaling is critical for macrophageinduced invasion of breast cancer cell lines
    • Pukrop T. 2006. Wnt 5α signaling is critical for macrophageinduced invasion of breast cancer cell lines. Proc Nat Acad Sci 103: 5454-5459.
    • (2006) Proc Nat Acad Sci , vol.103 , pp. 5454-5459
    • Pukrop, T.1
  • 132
    • 47249140444 scopus 로고    scopus 로고
    • Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: A potential mechanism underlying osteolytic bone lesions in multiple myeloma
    • Qiang Y-W, Chen Y, Stephens O, Brown N, Chen B, Epstei J, Barlogie B, Shaughnessy JDJ. 2008. Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: A potential mechanism underlying osteolytic bone lesions in multiple myeloma. Blood 112: 196-207.
    • (2008) Blood , vol.112 , pp. 196-207
    • Qiang, Y-W.1    Chen, Y.2    Stephens, O.3    Brown, N.4    Chen, B.5    Epstei, J.6    Barlogie, B.7    Shaughnessy, J.D.J.8
  • 134
    • 0037179894 scopus 로고    scopus 로고
    • Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
    • Rhee C-S, Sen M, Lu D, Wu C, Leoni L, Rubin J, Corr M, Carson DA. 2002. Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas. Oncogene 21: 6598-6605.
    • (2002) Oncogene , vol.21 , pp. 6598-6605
    • Rhee, C-S.1    Sen, M.2    Lu, D.3    Wu, C.4    Leoni, L.5    Rubin, J.6    Corr, M.7    Carson, D.A.8
  • 135
    • 0023653232 scopus 로고
    • The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless
    • Rijsewijk F. 1987. The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell 50: 649-657.
    • (1987) Cell , vol.50 , pp. 649-657
    • Rijsewijk, F.1
  • 137
    • 33748768971 scopus 로고    scopus 로고
    • Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors
    • Rodda SJ, McMahon AP. 2006. Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development (Cambridge, England) 133: 3231-3244.
    • (2006) Development (Cambridge, England) , vol.133 , pp. 3231-3244
    • Rodda, S.J.1    McMahon, A.P.2
  • 138
    • 34447115083 scopus 로고    scopus 로고
    • Haloperidol and clozapine differentially regulate signals upstream of glycogen synthase kinase 3 in the rat frontal cortex
    • Roh M-S, Seo MS, Kim Y, Kim SH, Jeon WJ, Ahn YM, Kan UG, Juhnn YS, Kim YS. 2007. Haloperidol and clozapine differentially regulate signals upstream of glycogen synthase kinase 3 in the rat frontal cortex. Exp Molec Med 39: 353-360.
    • (2007) Exp Molec Med , vol.39 , pp. 353-360
    • Roh, M-S.1    Seo, M.S.2    Kim, Y.3    Kim, S.H.4    Jeon, W.J.5    Ahn, Y.M.6    Kan, U.G.7    Juhnn, Y.S.8    Kim, Y.S.9
  • 139
    • 33645789040 scopus 로고    scopus 로고
    • A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells
    • Säfholm A, Leandersson K, Dejmek J, Nielsen CK, Villoutrei BO, Andersson T. 2006. A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells. J Biol Chem 281: 2740-2749.
    • (2006) J Biol Chem , vol.281 , pp. 2740-2749
    • Säfholm, A.1    Leandersson, K.2    Dejmek, J.3    Nielsen, C.K.4    Villoutrei, B.O.5    Andersson, T.6
  • 140
    • 48249110960 scopus 로고    scopus 로고
    • Wnt signaling in neural circuit assembly
    • Salinas PC, Zou Y. 2008. Wnt signaling in neural circuit assembly. Annu Rev Neurosci 31: 339-358.
    • (2008) Annu Rev Neurosci , vol.31 , pp. 339-358
    • Salinas, P.C.1    Zou, Y.2
  • 141
    • 78649747488 scopus 로고    scopus 로고
    • Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling
    • Saraswati S, AlfaroMP, Thorne CA, Atkinson J, Lee E, Youn PP. 2010. Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling. PloS ONE 5: e15521.
    • (2010) PloS ONE , vol.5
    • Saraswati, S.1    Alfaro, M.P.2    Thorne, C.A.3    Atkinson, J.4    Lee, E.5    Youn, P.P.6
  • 142
  • 143
    • 22844445934 scopus 로고    scopus 로고
    • SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor
    • Semënov M, Tamai K, He X. 2005. SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor. J Biol Chem 280: 26770-26775.
    • (2005) J Biol Chem , vol.280 , pp. 26770-26775
    • Semënov, M.1    Tamai, K.2    He, X.3
  • 145
    • 0035049281 scopus 로고    scopus 로고
    • Blockade of Wnt-5A/Frizzled 5 signaling inhibits rheumatoid synoviocyte activation
    • Sen M, Chamorro M, Reifert J, Corr M, Carson DA. 2001. Blockade of Wnt-5A/Frizzled 5 signaling inhibits rheumatoid synoviocyte activation. Arthritis Rheum 44: 772-781.
    • (2001) Arthritis Rheum , vol.44 , pp. 772-781
    • Sen, M.1    Chamorro, M.2    Reifert, J.3    Corr, M.4    Carson, D.A.5
  • 146
    • 0036845163 scopus 로고    scopus 로고
    • Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes
    • Sen M, Reifert J, Lauterbach K, Wolf V, Rubin JS, Corr M, Carson DA. 2002. Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes. Arthritis Rheum 46: 2867-2877.
    • (2002) Arthritis Rheum , vol.46 , pp. 2867-2877
    • Sen, M.1    Reifert, J.2    Lauterbach, K.3    Wolf, V.4    Rubin, J.S.5    Corr, M.6    Carson, D.A.7
  • 147
    • 79952527740 scopus 로고    scopus 로고
    • Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance
    • Shafer B, Onishi K, Lo C, Colakoglu G, Zou Y. 2011. Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance. Dev Cell 20: 177-191.
    • (2011) Dev Cell , vol.20 , pp. 177-191
    • Shafer, B.1    Onishi, K.2    Lo, C.3    Colakoglu, G.4    Zou, Y.5
  • 148
    • 28244496603 scopus 로고    scopus 로고
    • Identification of a specific inhibitor of the dishevelled PDZ domain
    • Shan J, Shi D-L, Wang J, Zheng J. 2005. Identification of a specific inhibitor of the dishevelled PDZ domain. Biochemistry 44: 15495-15503.
    • (2005) Biochemistry , vol.44 , pp. 15495-15503
    • Shan, J.1    Shi, D-L.2    Wang, J.3    Zheng, J.4
  • 153
    • 0027756014 scopus 로고
    • Association of the APC tumor suppressor protein with catenins
    • Su L, Vogelstein B, Kinzler K. 1993. Association of the APC tumor suppressor protein with catenins. Science 262: 1734-1737.
    • (1993) Science , vol.262 , pp. 1734-1737
    • Su, L.1    Vogelstein, B.2    Kinzler, K.3
  • 155
    • 78650482080 scopus 로고    scopus 로고
    • Noncanonical Wnt signaling in vertebrate development, stem cells, and diseases
    • Sugimura R, Li L. 2010. Noncanonical Wnt signaling in vertebrate development, stem cells, and diseases. Birth Defects Res C Embryo Today 90: 243-256.
    • (2010) Birth Defects Res C Embryo Today , vol.90 , pp. 243-256
    • Sugimura, R.1    Li, L.2
  • 157
    • 28444468088 scopus 로고    scopus 로고
    • Wnt-dependent β-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis
    • Surendran K, Schiavi S, Hruska KA. 2005. Wnt-dependent β-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis. J A Soc Nephrol 16: 2373-2384.
    • (2005) J A Soc Nephrol , vol.16 , pp. 2373-2384
    • Surendran, K.1    Schiavi, S.2    Hruska, K.A.3
  • 162
    • 33745826247 scopus 로고    scopus 로고
    • The glucocorticoid receptor represses cyclin D1 by targeting the Tcf-β-catenin complex
    • Takayama S, Rogatsky I, Schwarcz LE, Darimont BD. 2006. The glucocorticoid receptor represses cyclin D1 by targeting the Tcf-β-catenin complex. J Biol Chem 281: 17856-17863.
    • (2006) J Biol Chem , vol.281 , pp. 17856-17863
    • Takayama, S.1    Rogatsky, I.2    Schwarcz, L.E.3    Darimont, B.D.4
  • 165
    • 0346363760 scopus 로고    scopus 로고
    • The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
    • Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, Barlogie B, Shaughnessy JD Jr. 2003. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 349: 2483-2494.
    • (2003) N Engl J Med , vol.349 , pp. 2483-2494
    • Tian, E.1    Zhan, F.2    Walker, R.3    Rasmussen, E.4    Ma, Y.5    Barlogie, B.6    Shaughnessy Jr., J.D.7
  • 166
    • 77249109792 scopus 로고    scopus 로고
    • Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1δE9 mouse model of Alzheimer's disease
    • Toledo EM, Inestrosa NC. 2010. Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1δE9 mouse model of Alzheimer's disease. Mol Psychiatry 15: 228, 272-285.
    • (2010) Mol Psychiatry , vol.15
    • Toledo, E.M.1    Inestrosa, N.C.2
  • 168
    • 79551676333 scopus 로고    scopus 로고
    • Alterations in Wnt pathway activity in mouse serum and kidneys during lupus development
    • Tveita AA, Rekvig OP. 2011. Alterations in Wnt pathway activity in mouse serum and kidneys during lupus development. Arthritis Rheum 63: 513-522.
    • (2011) Arthritis Rheum , vol.63 , pp. 513-522
    • Tveita, A.A.1    Rekvig, O.P.2
  • 170
    • 0242551656 scopus 로고    scopus 로고
    • Activation of the Wnt pathway in non small cell lung cancer: Evidence of dishevelled overexpression
    • Uematsu K, He B, You L, Xu Z, McCormick F, Jablons DM. 2003a. Activation of the Wnt pathway in non small cell lung cancer: Evidence of dishevelled overexpression. Oncogene 22: 7218-7221.
    • (2003) Oncogene , vol.22 , pp. 7218-7221
    • Uematsu, K.1    He, B.2    You, L.3    Xu, Z.4    McCormick, F.5    Jablons, D.M.6
  • 171
    • 0043092191 scopus 로고    scopus 로고
    • Wnt pathway activation in mesothelioma: Evidence of Dishevelled overexpression and transcriptional activity of β-catenin
    • Uematsu K, Kanazawa S, You L, He B, Xu Z, Li K, Peterli BM, McCormick F, Jablons DM. 2003b. Wnt pathway activation in mesothelioma: Evidence of Dishevelled overexpression and transcriptional activity of β-catenin. Cancer Res 63: 4547-4551.
    • (2003) Cancer Res , vol.63 , pp. 4547-4551
    • Uematsu, K.1    Kanazawa, S.2    You, L.3    He, B.4    Xu, Z.5    Li, K.6    Peterli, B.M.7    McCormick, F.8    Jablons, D.M.9
  • 175
    • 60849103074 scopus 로고    scopus 로고
    • Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells
    • Vijayaragavan K, Szabo E, Bossé M, Ramos-Mejia V, Moo RT, Bhatia M. 2009. Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells. Cell Stem Cell 4: 248-262.
    • (2009) Cell Stem Cell , vol.4 , pp. 248-262
    • Vijayaragavan, K.1    Szabo, E.2    Bossé, M.3    Ramos-Mejia, V.4    Moo, R.T.5    Bhatia, M.6
  • 176
    • 23844461568 scopus 로고    scopus 로고
    • Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth
    • Vincan E, Darcy PK, Smyth MJ, Thompson EW, Thoma RJ. S, Phillips WA, Ramsay RG. 2005. Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth. Differentiation 73: 142-153.
    • (2005) Differentiation , vol.73 , pp. 142-153
    • Vincan, E.1    Darcy, P.K.2    Smyth, M.J.3    Thompson, E.W.4    Thoma, R.J.S.5    Phillips, W.A.6    Ramsay, R.G.7
  • 177
    • 77956938052 scopus 로고    scopus 로고
    • Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling
    • von Marschall Z, Fisher LW. 2010. Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling. Biochem Biophys Res Commun 400: 299-304.
    • (2010) Biochem Biophys Res Commun , vol.400 , pp. 299-304
    • von Marschall, Z.1    Fisher, L.W.2
  • 178
    • 70349878466 scopus 로고    scopus 로고
    • WNT and BMP signaling are both required for hematopoietic cell development from human ES cells
    • Wang Y, Nakayama N. 2009. WNT and BMP signaling are both required for hematopoietic cell development from human ES cells. Stem Cell Res 3: 113-125.
    • (2009) Stem Cell Res , vol.3 , pp. 113-125
    • Wang, Y.1    Nakayama, N.2
  • 179
    • 33846025409 scopus 로고    scopus 로고
    • Knocking down dickkopf-1 alleviates estrogen deficiency induction of bone loss. A histomorphological study in ovariectomized rats
    • Wang F-S, Ko J-Y, Lin C-L, Wu H-L, Ke H-J, Tai P-J. 2007. Knocking down dickkopf-1 alleviates estrogen deficiency induction of bone loss. A histomorphological study in ovariectomized rats. Bone 40: 485-492.
    • (2007) Bone , vol.40 , pp. 485-492
    • Wang, F-S.1    Ko, J-Y.2    Lin, C-L.3    Wu, H-L.4    Ke, H-J.5    Tai, P-J.6
  • 180
    • 41549138806 scopus 로고    scopus 로고
    • Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss
    • Wang F-S, Ko J-Y, Yeh D-W, Ke H-C, Wu H-L. 2008. Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss. Endocrinology 149: 1793-1801.
    • (2008) Endocrinology , vol.149 , pp. 1793-1801
    • Wang, F-S.1    Ko, J-Y.2    Yeh, D-W.3    Ke, H-C.4    Wu, H-L.5
  • 181
    • 79951936909 scopus 로고    scopus 로고
    • Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/β-catenin signaling
    • Wang H, Hao J, Hong CC. 2011a. Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/β-catenin signaling. ACS Chem Biol 6: 192-197.
    • (2011) ACS Chem Biol , vol.6 , pp. 192-197
    • Wang, H.1    Hao, J.2    Hong, C.C.3
  • 182
    • 79955613593 scopus 로고    scopus 로고
    • A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/β-catenin signaling and colon cancer cell tumorigenesis
    • Wang W, Liu H, Wang S, Hao X, Li L. 2011b. A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/β-catenin signaling and colon cancer cell tumorigenesis. Cell Res 21: 730-740.
    • (2011) Cell Res , vol.21 , pp. 730-740
    • Wang, W.1    Liu, H.2    Wang, S.3    Hao, X.4    Li, L.5
  • 184
    • 70449366626 scopus 로고    scopus 로고
    • Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells
    • Wei W, Chua MS, Grepper S, So SK. 2009. Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells. Mol Cancer 8: 76.
    • (2009) Mol Cancer , vol.8 , pp. 76
    • Wei, W.1    Chua, M.S.2    Grepper, S.3    So, S.K.4
  • 185
    • 79751531916 scopus 로고    scopus 로고
    • Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin
    • Wei W, Chua M-S, Grepper S, So SK. 2011. Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin. Mol Cancer 10: 16.
    • (2011) Mol Cancer , vol.10 , pp. 16
    • Wei, W.1    Chua, M-S.2    Grepper, S.3    So, S.K.4
  • 188
    • 42349093195 scopus 로고    scopus 로고
    • Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors
    • Witze ES, Litman ES, Argast GM, Moon RT, Ahn NG. 2008. Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors. Science (New York, NY) 320: 365-369.
    • (2008) Science (New York, NY) , vol.320 , pp. 365-369
    • Witze, E.S.1    Litman, E.S.2    Argast, G.M.3    Moon, R.T.4    Ahn, N.G.5
  • 189
    • 0036154038 scopus 로고    scopus 로고
    • Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours
    • Wong SCC, Lo SFE, Lee KC, Yam JWP, Chan JK. C, Wend Hsiao WL. 2002. Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours. J Pathol 196: 145-153.
    • (2002) J Pathol , vol.196 , pp. 145-153
    • Wong, S.C.C.1    Lo, S.F.E.2    Lee, K.C.3    Yam, J.W.P.4    Chan, J.K.C.5    Wend Hsiao, W.L.6
  • 190
    • 0036839056 scopus 로고    scopus 로고
    • Evidence for regulation of long terminal repeat transcription by Wnt transcription factor TCF-4 in human astrocytic cells
    • Wortman B, Darbinian N, Sawaya BE, Khalili K, Amini S. 2002. Evidence for regulation of long terminal repeat transcription by Wnt transcription factor TCF-4 in human astrocytic cells. J Virol 76: 11159-11165.
    • (2002) J Virol , vol.76 , pp. 11159-11165
    • Wortman, B.1    Darbinian, N.2    Sawaya, B.E.3    Khalili, K.4    Amini, S.5
  • 191
    • 0034649592 scopus 로고    scopus 로고
    • Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/ β-catenin signalling
    • Wu W, Glinka A, Delius H, Niehrs C. 2000. Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/ β-catenin signalling. Curr Biol 10: 1611-1614.
    • (2000) Curr Biol , vol.10 , pp. 1611-1614
    • Wu, W.1    Glinka, A.2    Delius, H.3    Niehrs, C.4
  • 192
    • 0043032524 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC)-independent regulation of β-catenin degradation via a retinoidXreceptor-mediated pathway
    • Xiao J-H, Ghosn C, Hinchman C, Forbes C, Wang J, Snide N, Cordrey A, Zhao Y, Chandraratna RAS. 2003. Adenomatous polyposis coli (APC)-independent regulation of β-catenin degradation via a retinoidXreceptor-mediated pathway. J Biol Chem 278: 29954-29962.
    • (2003) J Biol Chem , vol.278 , pp. 29954-29962
    • Xiao, J-H.1    Ghosn, C.2    Hinchman, C.3    Forbes, C.4    Wang, J.5    Snide, N.6    Cordrey, A.7    Zhao, Y.8    Chandraratna, R.A.S.9
  • 194
    • 46049089076 scopus 로고    scopus 로고
    • Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of β-catenin signaling
    • Yamamoto H, Sakane H, Michiue T, Kikuchi A. 2008. Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of β-catenin signaling. Dev Cell 15: 37-48.
    • (2008) Dev Cell , vol.15 , pp. 37-48
    • Yamamoto, H.1    Sakane, H.2    Michiue, T.3    Kikuchi, A.4
  • 195
    • 78649704164 scopus 로고    scopus 로고
    • Cardiomyocytes develop from anterior primitive streak cells induced by β-catenin activation and the blockage of BMP signaling in hESCs
    • Yamauchi K, Sumi T, Minami I, Otsuji TG, Kawase E, Nakatsuj N, Suemori H. 2010. Cardiomyocytes develop from anterior primitive streak cells induced by β-catenin activation and the blockage of BMP signaling in hESCs. Genes Cells 15: 1216-1227.
    • (2010) Genes Cells , vol.15 , pp. 1216-1227
    • Yamauchi, K.1    Sumi, T.2    Minami, I.3    Otsuji, T.G.4    Kawase, E.5    Nakatsuj, N.6    Suemori, H.7
  • 201
    • 77953959985 scopus 로고    scopus 로고
    • TCF1 and β-catenin regulate T cell development and function
    • Yu Q, Sharma A, Sen JM. 2010. TCF1 and β-catenin regulate T cell development and function. Immunol Res 47: 45-55.
    • (2010) Immunol Res , vol.47 , pp. 45-55
    • Yu, Q.1    Sharma, A.2    Sen, J.M.3
  • 202
    • 58249106842 scopus 로고    scopus 로고
    • Lithium's effect on bone mineral density
    • Zamani A, Omrani GR, Nasab MM. 2009. Lithium's effect on bone mineral density. Bone 44: 331-334.
    • (2009) Bone , vol.44 , pp. 331-334
    • Zamani, A.1    Omrani, G.R.2    Nasab, M.M.3


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