Sulindac targets nuclear β-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines

British Journal of Cancer

Volumn 90, Issue 1, 2004, Pages 224-229

  Boon, E M J ^a   Keller, J J ^a   Wormhoudt, T A M ^a   Giardiello, F M ^b   Offerhaus, G J A ^a   Van Der Neut, R ^a   Pals, S T ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

FAP; Sulindac; TCF

Indexed keywords

BETA CATENIN; CYCLIN D1; CYCLOOXYGENASE 2; NONSTEROID ANTIINFLAMMATORY AGENT; SCATTER FACTOR RECEPTOR; SULINDAC; SULINDAC SULFIDE; T CELL FACTOR PROTEIN; WNT PROTEIN;

ADENOMA; ADENOMATOUS POLYP; ADULT; ARTICLE; CANCER CELL; CELL LINE; CELL NUCLEUS; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG TARGETING; FEMALE; FOLLOW UP; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TARGET CELL DESTRUCTION; TRANSCRIPTION INITIATION;

ADENOMA; ADENOMATOUS POLYPOSIS COLI; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BETA CATENIN; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; CHEMOPREVENTION; COLORECTAL NEOPLASMS; CYTOSKELETAL PROTEINS; FEMALE; HUMANS; MITOGENS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; SULINDAC; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; WNT PROTEINS; ZEBRAFISH PROTEINS;

EID: 0842329914     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6601505     Document Type: Article

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