메뉴 건너뛰기




Volumn 11, Issue 6, 2006, Pages 791-801

Monounsaturated Fatty Acid Modification of Wnt Protein: Its Role in Wnt Secretion

Author keywords

CELLBIO; SIGNALING

Indexed keywords

ACYLTRANSFERASE; ALANINE; CYSTEINE; LIPID; MONOUNSATURATED FATTY ACID; PALMITIC ACID; PALMITOLEIC ACID; PORCUPINE PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG; WNT PROTEIN; WNT3A PROTEIN;

EID: 33751318469     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2006.10.003     Document Type: Article
Times cited : (619)

References (49)
  • 1
    • 33646134826 scopus 로고    scopus 로고
    • Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
    • Banziger C., Soldini D., Schutt C., Zipperlen P., Hausmann G., and Basler K. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 125 (2006) 509-522
    • (2006) Cell , vol.125 , pp. 509-522
    • Banziger, C.1    Soldini, D.2    Schutt, C.3    Zipperlen, P.4    Hausmann, G.5    Basler, K.6
  • 2
    • 33646123992 scopus 로고    scopus 로고
    • Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
    • Bartscherer K., Pelte N., Ingelfinger D., and Boutros M. Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125 (2006) 523-533
    • (2006) Cell , vol.125 , pp. 523-533
    • Bartscherer, K.1    Pelte, N.2    Ingelfinger, D.3    Boutros, M.4
  • 3
    • 0029022642 scopus 로고
    • Chemical analysis of acylation sites and species
    • Bizzozero O.A. Chemical analysis of acylation sites and species. Methods Enzymol. 250 (1995) 361-379
    • (1995) Methods Enzymol. , vol.250 , pp. 361-379
    • Bizzozero, O.A.1
  • 4
    • 0030601956 scopus 로고    scopus 로고
    • Activation of Siamois by the Wnt pathway
    • Brannon M., and Kimelman D. Activation of Siamois by the Wnt pathway. Dev. Biol. 180 (1996) 344-347
    • (1996) Dev. Biol. , vol.180 , pp. 344-347
    • Brannon, M.1    Kimelman, D.2
  • 6
    • 33646592268 scopus 로고    scopus 로고
    • Wnt gradient formation requires retromer function in Wnt-producing cells
    • Coudreuse D.Y., Roel G., Betist M.C., Destree O., and Korswagen H.C. Wnt gradient formation requires retromer function in Wnt-producing cells. Science 312 (2006) 921-924
    • (2006) Science , vol.312 , pp. 921-924
    • Coudreuse, D.Y.1    Roel, G.2    Betist, M.C.3    Destree, O.4    Korswagen, H.C.5
  • 11
    • 0035823004 scopus 로고    scopus 로고
    • Argosomes: a potential vehicle for the spread of morphogens through epithelia
    • Greco V., Hannus M., and Eaton S. Argosomes: a potential vehicle for the spread of morphogens through epithelia. Cell 106 (2001) 633-645
    • (2001) Cell , vol.106 , pp. 633-645
    • Greco, V.1    Hannus, M.2    Eaton, S.3
  • 12
    • 21744450786 scopus 로고    scopus 로고
    • Heparan sulphate proteoglycans: the sweet side of development
    • Hacker U., Nybakken K., and Perrimon N. Heparan sulphate proteoglycans: the sweet side of development. Nat. Rev. Mol. Cell Biol. 6 (2005) 530-541
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 530-541
    • Hacker, U.1    Nybakken, K.2    Perrimon, N.3
  • 13
    • 0034161499 scopus 로고    scopus 로고
    • A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling
    • Hofmann K. A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling. Trends Biochem. Sci. 25 (2000) 111-112
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 111-112
    • Hofmann, K.1
  • 14
    • 25844522857 scopus 로고    scopus 로고
    • Modulation of neuronal protein trafficking and function by palmitoylation
    • Huang K., and El-Husseini A. Modulation of neuronal protein trafficking and function by palmitoylation. Curr. Opin. Neurobiol. 15 (2005) 527-535
    • (2005) Curr. Opin. Neurobiol. , vol.15 , pp. 527-535
    • Huang, K.1    El-Husseini, A.2
  • 16
    • 0030450052 scopus 로고    scopus 로고
    • The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing
    • Kadowaki T., Wilder E., Klingensmith J., Zachary K., and Perrimon N. The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes Dev. 10 (1996) 3116-3128
    • (1996) Genes Dev. , vol.10 , pp. 3116-3128
    • Kadowaki, T.1    Wilder, E.2    Klingensmith, J.3    Zachary, K.4    Perrimon, N.5
  • 17
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 18
    • 0026786031 scopus 로고
    • Lipid modification at the N terminus of photoreceptor G-protein α-subunit
    • Kokame K., Fukada Y., Yoshizawa T., Takao T., and Shimonishi Y. Lipid modification at the N terminus of photoreceptor G-protein α-subunit. Nature 359 (1992) 749-752
    • (1992) Nature , vol.359 , pp. 749-752
    • Kokame, K.1    Fukada, Y.2    Yoshizawa, T.3    Takao, T.4    Shimonishi, Y.5
  • 19
    • 0035368725 scopus 로고    scopus 로고
    • Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1
    • Lewis P.M., Dunn M.P., McMahon J.A., Logan M., Martin J.F., St-Jacques B., and McMahon A.P. Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell 105 (2001) 599-612
    • (2001) Cell , vol.105 , pp. 599-612
    • Lewis, P.M.1    Dunn, M.P.2    McMahon, J.A.3    Logan, M.4    Martin, J.F.5    St-Jacques, B.6    McMahon, A.P.7
  • 20
    • 0035903208 scopus 로고    scopus 로고
    • Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction
    • Liang X., Nazarian A., Erdjument-Bromage H., Bornmann W., Tempst P., and Resh M.D. Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction. J. Biol. Chem. 276 (2001) 30987-30994
    • (2001) J. Biol. Chem. , vol.276 , pp. 30987-30994
    • Liang, X.1    Nazarian, A.2    Erdjument-Bromage, H.3    Bornmann, W.4    Tempst, P.5    Resh, M.D.6
  • 21
    • 12344310615 scopus 로고    scopus 로고
    • Functions of heparan sulfate proteoglycans in cell signaling during development
    • Lin X. Functions of heparan sulfate proteoglycans in cell signaling during development. Development 131 (2004) 6009-6021
    • (2004) Development , vol.131 , pp. 6009-6021
    • Lin, X.1
  • 22
    • 0038321812 scopus 로고    scopus 로고
    • New insights into the mechanisms of protein palmitoylation
    • Linder M.E., and Deschenes R.J. New insights into the mechanisms of protein palmitoylation. Biochemistry 42 (2003) 4311-4320
    • (2003) Biochemistry , vol.42 , pp. 4311-4320
    • Linder, M.E.1    Deschenes, R.J.2
  • 23
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan C.Y., and Nusse R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20 (2004) 781-810
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 24
    • 2942742564 scopus 로고    scopus 로고
    • Novel lipid modifications of secreted protein signals
    • Mann R.K., and Beachy P.A. Novel lipid modifications of secreted protein signals. Annu. Rev. Biochem. 73 (2004) 891-923
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 891-923
    • Mann, R.K.1    Beachy, P.A.2
  • 25
    • 18744425721 scopus 로고    scopus 로고
    • LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter
    • McKendry R., Hsu S.C., Harland R.M., and Grosschedl R. LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter. Dev. Biol. 192 (1997) 420-431
    • (1997) Dev. Biol. , vol.192 , pp. 420-431
    • McKendry, R.1    Hsu, S.C.2    Harland, R.M.3    Grosschedl, R.4
  • 26
    • 31744439979 scopus 로고    scopus 로고
    • Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion
    • Miura G.I., Buglino J., Alvarado D., Lemmon M.A., Resh M.D., and Treisman J.E. Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion. Dev. Cell 10 (2006) 167-176
    • (2006) Dev. Cell , vol.10 , pp. 167-176
    • Miura, G.I.1    Buglino, J.2    Alvarado, D.3    Lemmon, M.A.4    Resh, M.D.5    Treisman, J.E.6
  • 27
    • 0034695484 scopus 로고    scopus 로고
    • Lipid-dependent targeting of G proteins into rafts
    • Moffett S., Brown D.A., and Linder M.E. Lipid-dependent targeting of G proteins into rafts. J. Biol. Chem. 275 (2000) 2191-2198
    • (2000) J. Biol. Chem. , vol.275 , pp. 2191-2198
    • Moffett, S.1    Brown, D.A.2    Linder, M.E.3
  • 29
    • 0027415193 scopus 로고
    • Myristoylation of proteins in platelets occurs predominantly through thioester linkages
    • Muszbek L., and Laposata M. Myristoylation of proteins in platelets occurs predominantly through thioester linkages. J. Biol. Chem. 268 (1993) 8251-8255
    • (1993) J. Biol. Chem. , vol.268 , pp. 8251-8255
    • Muszbek, L.1    Laposata, M.2
  • 30
    • 0026648586 scopus 로고
    • The rod transducin α subunit amino terminus is heterogeneously fatty acylated
    • Neubert T.A., Johnson R.S., Hurley J.B., and Walsh K.A. The rod transducin α subunit amino terminus is heterogeneously fatty acylated. J. Biol. Chem. 267 (1992) 18274-18277
    • (1992) J. Biol. Chem. , vol.267 , pp. 18274-18277
    • Neubert, T.A.1    Johnson, R.S.2    Hurley, J.B.3    Walsh, K.A.4
  • 31
    • 0344464720 scopus 로고    scopus 로고
    • Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface
    • Nusse R. Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development 130 (2003) 5297-5305
    • (2003) Development , vol.130 , pp. 5297-5305
    • Nusse, R.1
  • 32
    • 18344378499 scopus 로고    scopus 로고
    • Lipoprotein particles are required for Hedgehog and Wingless signalling
    • Panakova D., Sprong H., Marois E., Thiele C., and Eaton S. Lipoprotein particles are required for Hedgehog and Wingless signalling. Nature 435 (2005) 58-65
    • (2005) Nature , vol.435 , pp. 58-65
    • Panakova, D.1    Sprong, H.2    Marois, E.3    Thiele, C.4    Eaton, S.5
  • 35
    • 0029844192 scopus 로고    scopus 로고
    • Cholesterol modification of hedgehog signaling proteins in animal development
    • Porter J.A., Young K.E., and Beachy P.A. Cholesterol modification of hedgehog signaling proteins in animal development. Science 274 (1996) 255-259
    • (1996) Science , vol.274 , pp. 255-259
    • Porter, J.A.1    Young, K.E.2    Beachy, P.A.3
  • 36
    • 33744507945 scopus 로고    scopus 로고
    • Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans
    • Prasad B.C., and Clark S.G. Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans. Development 133 (2006) 1757-1766
    • (2006) Development , vol.133 , pp. 1757-1766
    • Prasad, B.C.1    Clark, S.G.2
  • 37
    • 0032875098 scopus 로고    scopus 로고
    • Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins
    • Resh M.D. Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. Biochim. Biophys. Acta. 1451 (1999) 1-16
    • (1999) Biochim. Biophys. Acta. , vol.1451 , pp. 1-16
    • Resh, M.D.1
  • 38
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T., and Clevers H. Wnt signalling in stem cells and cancer. Nature 434 (2005) 843-850
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 39
    • 0035901484 scopus 로고    scopus 로고
    • Differential modulation of ACAT1 and ACAT2 transcription and activity by long chain free fatty acids in cultured cells
    • Seo T., Oelkers P.M., Giattina M.R., Worgall T.S., Sturley S.L., and Deckelbaum R.J. Differential modulation of ACAT1 and ACAT2 transcription and activity by long chain free fatty acids in cultured cells. Biochemistry 40 (2001) 4756-4762
    • (2001) Biochemistry , vol.40 , pp. 4756-4762
    • Seo, T.1    Oelkers, P.M.2    Giattina, M.R.3    Worgall, T.S.4    Sturley, S.L.5    Deckelbaum, R.J.6
  • 41
    • 3543099503 scopus 로고    scopus 로고
    • Palmitoylation of intracellular signaling proteins: regulation and function
    • Smotrys J.E., and Linder M.E. Palmitoylation of intracellular signaling proteins: regulation and function. Annu. Rev. Biochem. 73 (2004) 559-587
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 559-587
    • Smotrys, J.E.1    Linder, M.E.2
  • 42
    • 0026039487 scopus 로고
    • Injected Wnt RNA induces a complete body axis in Xenopus embryos
    • Sokol S., Christian J.L., Moon R.T., and Melton D.A. Injected Wnt RNA induces a complete body axis in Xenopus embryos. Cell 67 (1991) 741-752
    • (1991) Cell , vol.67 , pp. 741-752
    • Sokol, S.1    Christian, J.L.2    Moon, R.T.3    Melton, D.A.4
  • 43
    • 0037066744 scopus 로고    scopus 로고
    • Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum
    • Tanaka K., Kitagawa Y., and Kadowaki T. Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum. J. Biol. Chem. 277 (2002) 12816-12823
    • (2002) J. Biol. Chem. , vol.277 , pp. 12816-12823
    • Tanaka, K.1    Kitagawa, Y.2    Kadowaki, T.3
  • 44
    • 0030747773 scopus 로고    scopus 로고
    • Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm
    • Thorpe C.J., Schlesinger A., Carter J.C., and Bowerman B. Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm. Cell 90 (1997) 695-705
    • (1997) Cell , vol.90 , pp. 695-705
    • Thorpe, C.J.1    Schlesinger, A.2    Carter, J.C.3    Bowerman, B.4
  • 45
    • 0027368963 scopus 로고
    • Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein
    • van den Heuvel M., Harryman-Samos C., Klingensmith J., Perrimon N., and Nusse R. Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. EMBO J. 12 (1993) 5293-5302
    • (1993) EMBO J. , vol.12 , pp. 5293-5302
    • van den Heuvel, M.1    Harryman-Samos, C.2    Klingensmith, J.3    Perrimon, N.4    Nusse, R.5
  • 48
    • 4043154959 scopus 로고    scopus 로고
    • Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine
    • Zhai L., Chaturvedi D., and Cumberledge S. Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine. J. Biol. Chem. 279 (2004) 33220-33227
    • (2004) J. Biol. Chem. , vol.279 , pp. 33220-33227
    • Zhai, L.1    Chaturvedi, D.2    Cumberledge, S.3
  • 49
    • 3242769766 scopus 로고    scopus 로고
    • Long-chain saturated fatty acids induce annexin II translocation to detergent-resistant membranes
    • Zhao H., and Hardy R.W. Long-chain saturated fatty acids induce annexin II translocation to detergent-resistant membranes. Biochem. J. 381 (2004) 463-469
    • (2004) Biochem. J. , vol.381 , pp. 463-469
    • Zhao, H.1    Hardy, R.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.