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Volumn 3, Issue 7, 2001, Pages 628-636

PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; DISHEVELLED PROTEIN; GENE PRODUCT; PROTEIN KINASE; PROTEINASE ACTIVATED RECEPTOR 1; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 0034943604     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35083016     Document Type: Article
Times cited : (220)

References (50)
  • 4
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signalling in oncogenesis and embryogenesis - A look outside the nucleus
    • (2000) Science , vol.287 , pp. 1606-1609
    • Peifer, M.1    Polakis, V.2
  • 7
    • 0032898364 scopus 로고    scopus 로고
    • Dishevelled proteins lead to two signalling pathways: Regulation of LEF1 and cJun N-terminal kinase in mammalian cells
    • (1999) J. Biol. Chem. , vol.274 , pp. 129-134
    • Li, L.1
  • 9
    • 0028178391 scopus 로고
    • Dishevelled is required during wingless signalling to establish both cell polarity and cell identity
    • (1994) Development , vol.120 , pp. 347-360
    • Theisen, H.1
  • 13
    • 0029024475 scopus 로고
    • Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 14
    • 0034640112 scopus 로고    scopus 로고
    • The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole
    • (2000) Cell , vol.101 , pp. 377-388
    • Shulman, J.M.1    Benton, R.2    Johnston, D.S.3
  • 15
    • 0033775722 scopus 로고    scopus 로고
    • A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation
    • (2000) Nature Cell Biol. , vol.2 , pp. 458-460
    • Tomancak, P.1
  • 22
    • 0001003110 scopus 로고    scopus 로고
    • XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos
    • (1996) Cell , vol.86 , pp. 391-399
    • Molenaar, M.1
  • 23
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of β-catenin with the transcription factor LEF-1
    • (1996) Nature , vol.382 , pp. 638-642
    • Behrens, J.1
  • 24
    • 0345343608 scopus 로고    scopus 로고
    • Nuclear localization of β-catenin by interaction with transcription factor LEF-1
    • (1996) Mech. Dev. , vol.59 , pp. 3-10
    • Huber, O.1
  • 26
    • 0030949463 scopus 로고    scopus 로고
    • Activation of β-catenin-Tcf signalling in colon cancer by mutations in β-catenin or APC
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1
  • 28
    • 0031457978 scopus 로고    scopus 로고
    • The mouse Fused locus encodes Axin, an inhibitor of the Wnt signalling pathway that regulates embryonic axis formation
    • (1997) Cell , vol.90 , pp. 181-192
    • Zeng, L.1
  • 30
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the Wnt signalling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
    • (1998) EMBO J. , vol.17 , pp. 1371-1784
    • Ikeda, S.1
  • 31
    • 0034604076 scopus 로고    scopus 로고
    • Dishevelled controls cell polarity during Xenopus gastrulation
    • (2000) Nature , vol.405 , pp. 81-85
    • Wallingford, J.B.1
  • 32
    • 0034604096 scopus 로고    scopus 로고
    • Silberblick/Wntl 1 mediates convergent extension movements during zebrafish gastrulation
    • (2000) Nature , vol.405 , pp. 76-81
    • Heisenberg, C.-P.1
  • 33
    • 0032128173 scopus 로고    scopus 로고
    • From cortical rotation to organizer gene expression: Toward a molecular explanation of axis specification in Xenopus
    • (1998) BioEssays , vol.20 , pp. 536-545
    • Moon, R.T.1    Kimelman, D.X.2
  • 36
    • 0030293782 scopus 로고    scopus 로고
    • Analysis of Dishevelled signalling pathways during Xenopus development
    • (1996) Curr. Biol. , vol.6 , pp. 1456-1467
    • Sokol, S.Y.1
  • 40
    • 0032443021 scopus 로고    scopus 로고
    • Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the Wingless pathway
    • (1998) Cell , vol.95 , pp. 1017-1026
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 41
    • 0023879457 scopus 로고
    • Embryonic and imaginal requirements for wg, a segment polarity gene in Drosophila
    • (1988) Dev. Biol. , vol.125 , pp. 96-108
    • Baker, N.E.1
  • 43
    • 0030829387 scopus 로고    scopus 로고
    • Wnt signalling and an APC-related gene specify endoderm in early C. elegans embryos
    • (1997) Cell , vol.90 , pp. 707-716
    • Rocheleau, C.E.1
  • 46
    • 0032511194 scopus 로고    scopus 로고
    • GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis
    • (1998) Cell , vol.93 , pp. 1031-1041
    • Yost, C.1
  • 47
    • 0033517102 scopus 로고    scopus 로고
    • Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1
    • (1999) EMBO J. , vol.18 , pp. 4233-4240
    • Li, L.1
  • 48
    • 0029914169 scopus 로고    scopus 로고
    • Isolation and characterization of mouse dishevelled-3
    • (1996) Dev. Dynam. , vol.207 , pp. 253-262
    • Tsang, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.