-
1
-
-
0023922373
-
Purification and characterization of mouse hematopoietic stem cells
-
erratum 244, 1030 (1989)
-
Spangrude, G. J., Heimfeld, S. & Weissman, I. L. Purification and characterization of mouse hematopoietic stem cells. Science 241, 58-62 (1989); erratum 244, 1030 (1989).
-
(1989)
Science
, vol.241
, pp. 58-62
-
-
Spangrude, G.J.1
Heimfeld, S.2
Weissman, I.L.3
-
2
-
-
0026502896
-
+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow
-
+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow. J. Exp. Med. 175, 175-184 (1992).
-
(1992)
J. Exp. Med.
, vol.175
, pp. 175-184
-
-
Uchida, N.1
Weissman, I.L.2
-
3
-
-
0028534860
-
The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
-
Morrison, S. J. & Weissman, I. L. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1, 661-673 (1994).
-
(1994)
Immunity
, vol.1
, pp. 661-673
-
-
Morrison, S.J.1
Weissman, I.L.2
-
4
-
-
0034614576
-
Stem cells: Units of development, units of regeneration, and units in evolution
-
Weissman, I. L. Stem cells: units of development, units of regeneration, and units in evolution. Cell 100, 157-168 (2000).
-
(2000)
Cell
, vol.100
, pp. 157-168
-
-
Weissman, I.L.1
-
5
-
-
0033711624
-
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism
-
Reya, T. et al. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity 13, 15-24 (2000).
-
(2000)
Immunity
, vol.13
, pp. 15-24
-
-
Reya, T.1
-
6
-
-
0026672334
-
Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus
-
Hawley, R. G., Fong, A. Z., Burns, B. F. & Hawley, T. S. Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus. J. Exp. Med. 176, 1149-1163 (1992).
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1149-1163
-
-
Hawley, R.G.1
Fong, A.Z.2
Burns, B.F.3
Hawley, T.S.4
-
7
-
-
0033609070
-
T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant beta-catenin
-
Barth, A. I., Stewart, D. B. & Nelson, W. J. T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant beta-catenin. Proc. Natl Acad. Sci. USA 96, 4947-4952 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 4947-4952
-
-
Barth, A.I.1
Stewart, D.B.2
Nelson, W.J.3
-
8
-
-
0034684662
-
Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other
-
Domen, J. & Weissman, I. L. Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other. J. Exp. Med. 192, 1707-1718 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1707-1718
-
-
Domen, J.1
Weissman, I.L.2
-
9
-
-
0032980506
-
In vivo proliferation and cell cycle kinetics of long-term hematopoietic stem cells
-
Cheshier, S. H., Morrison, S. J., Liao, X. & Weissman, I. L. In vivo proliferation and cell cycle kinetics of long-term hematopoietic stem cells. Proc. Natl Acad. Sci. USA 96, 3120-3125 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 3120-3125
-
-
Cheshier, S.H.1
Morrison, S.J.2
Liao, X.3
Weissman, I.L.4
-
10
-
-
0028824811
-
The purification and characterization of fetal liver hematopoietic cells
-
Morrison, S. J., Hemmati, H. D., Wandycz, A. M. & Weissman, I. L. The purification and characterization of fetal liver hematopoietic cells. Proc. Natl Acad. Sci. USA 92, 10302-10306 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 10302-10306
-
-
Morrison, S.J.1
Hemmati, H.D.2
Wandycz, A.M.3
Weissman, I.L.4
-
11
-
-
0030927503
-
Phenotypic and functional changes induced at the clonal level in hematopoietic stem cells after 5-fluorouracil treatment
-
Randall, T. D. & Weissman, I. L. Phenotypic and functional changes induced at the clonal level in hematopoietic stem cells after 5-fluorouracil treatment. Blood 89, 3596-3606 (1997).
-
(1997)
Blood
, vol.89
, pp. 3596-3606
-
-
Randall, T.D.1
Weissman, I.L.2
-
12
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
advance online publication, 27 April (doi: 10.1038/nature 01611)
-
Willert, K. et al. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature advance online publication, 27 April 2003 (doi: 10.1038/nature01611).
-
(2003)
Nature
-
-
Willert, K.1
-
13
-
-
0033616573
-
Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein
-
Hsieh, J. C., Rattner, A., Smallwood, P. M. & Nathans, J. Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein. Proc. Natl Acad. Sci. USA 96, 3546-3551 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 3546-3551
-
-
Hsieh, J.C.1
Rattner, A.2
Smallwood, P.M.3
Nathans, J.4
-
14
-
-
0032577556
-
Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing
-
Cadigan, K. M., Fish, M. P., Rulifson, E. J. & Nusse, R. Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing. Cell 93, 767-777 (1998).
-
(1998)
Cell
, vol.93
, pp. 767-777
-
-
Cadigan, K.M.1
Fish, M.P.2
Rulifson, E.J.3
Nusse, R.4
-
15
-
-
0031457978
-
The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation
-
Zeng, L. et al. The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell 90, 181-192 (1997).
-
(1997)
Cell
, vol.90
, pp. 181-192
-
-
Zeng, L.1
-
16
-
-
0032539945
-
Bridging of β-catenin and glycogen synthase kinase-3β by axin and inhibition of β-catenin-mediated transcription
-
Sakanaka, C., Weiss, J. B. & Williams, L. T. Bridging of β-catenin and glycogen synthase kinase-3β by axin and inhibition of β-catenin-mediated transcription. Proc. Natl Acad. Sci. USA 95, 3020-3023 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 3020-3023
-
-
Sakanaka, C.1
Weiss, J.B.2
Williams, L.T.3
-
17
-
-
0032473355
-
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
-
Ikeda, S. et al. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin. EMBO J. 17, 1371-1384 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 1371-1384
-
-
Ikeda, S.1
-
18
-
-
0031943002
-
Axil,a member of the Axin family, interacts with both glycogen synthase kinase 3β and β-catenin and inhibits axis formation of Xenopus embryos
-
Yamamoto, H. et al. Axil,a member of the Axin family, interacts with both glycogen synthase kinase 3β and β-catenin and inhibits axis formation of Xenopus embryos. Mol. Cell Biol. 18, 2867-2875 (1998).
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 2867-2875
-
-
Yamamoto, H.1
-
19
-
-
0032492954
-
Downregulation of β-catenin by human Axin and its association with the APC tumour suppressor, β-catenin and GSK3 β
-
Hart, M. J., de los Santos, R., Albert, I. N., Rubinfeld, B. & Polakis, P. Downregulation of β-catenin by human Axin and its association with the APC tumour suppressor, β-catenin and GSK3 β. Curr. Biol. 8, 573-581 (1998).
-
(1998)
Curr. Biol.
, vol.8
, pp. 573-581
-
-
Hart, M.J.1
De los Santos, R.2
Albert, I.N.3
Rubinfeld, B.4
Polakis, P.5
-
20
-
-
0033694305
-
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch 1 signaling
-
Varnum-Finney, B. et al. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling. Nature Med. 6, 1278-1281 (2000).
-
(2000)
Nature Med.
, vol.6
, pp. 1278-1281
-
-
Varnum-Finney, B.1
-
21
-
-
0037023528
-
HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
-
Antonchuk, J., Sauvageau, G. & Humphries, R. K. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell 109, 39-45 (2002).
-
(2002)
Cell
, vol.109
, pp. 39-45
-
-
Antonchuk, J.1
Sauvageau, G.2
Humphries, R.K.3
-
22
-
-
0037130961
-
A stem cell molecular signature
-
Ivanova, N. B. et al. A stem cell molecular signature. Science 298, 601-604 (2002).
-
(2002)
Science
, vol.298
, pp. 601-604
-
-
Ivanova, N.B.1
-
23
-
-
0031440921
-
Expansion in vitro of adult murine hematopoietic stem cells with transplantable lympho-myeloid reconstituting ability
-
Miller, C. L. & Eaves, C. J. Expansion in vitro of adult murine hematopoietic stem cells with transplantable lympho-myeloid reconstituting ability. Proc. Natl Acad. Sci. USA 94, 13648-13653 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13648-13653
-
-
Miller, C.L.1
Eaves, C.J.2
-
24
-
-
0031946216
-
Advances in hematopoietic stem cell culture
-
Audet, J., Zandstra, P. W., Eaves, C. J. & Piret, J. M. Advances in hematopoietic stem cell culture. Curr. Opin. Biotechnol. 9, 146-151 (1998).
-
(1998)
Curr. Opin. Biotechnol.
, vol.9
, pp. 146-151
-
-
Audet, J.1
Zandstra, P.W.2
Eaves, C.J.3
Piret, J.M.4
-
25
-
-
0035257660
-
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation
-
Bhardwaj, G. et al. Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nature Immunol. 2, 172-180 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 172-180
-
-
Bhardwaj, G.1
-
26
-
-
0034629129
-
Hematopoietic stem cell quiescence maintained by p21cip1/waf 1
-
Cheng, T. et al. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 287, 1804-1808 (2000).
-
(2000)
Science
, vol.287
, pp. 1804-1808
-
-
Cheng, T.1
-
27
-
-
0027979091
-
Modulation of wingless signaling by Notch in Drosophila
-
Hing, H. K., Sun, X. & Artavanis-Tsakonas, S. Modulation of wingless signaling by Notch in Drosophila. Mech. Dev. 47, 261-268 (1994).
-
(1994)
Mech. Dev.
, vol.47
, pp. 261-268
-
-
Hing, H.K.1
Sun, X.2
Artavanis-Tsakonas, S.3
-
28
-
-
0032960350
-
A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans
-
Maloof, J. N., Whangbo, J., Harris, J. M., Jongeward, G. D. & Kenyon, C. A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans. Development 126, 37-49 (1999).
-
(1999)
Development
, vol.126
, pp. 37-49
-
-
Maloof, J.N.1
Whangbo, J.2
Harris, J.M.3
Jongeward, G.D.4
Kenyon, C.5
-
29
-
-
0028077841
-
Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos
-
Hooper, J. E. Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos. Nature 372, 461-464 (1994).
-
(1994)
Nature
, vol.372
, pp. 461-464
-
-
Hooper, J.E.1
-
30
-
-
0027408032
-
Regulation of wingless transcription in the Drosophila embryo
-
Ingham, P. W. & Hidalgo, A. Regulation of wingless transcription in the Drosophila embryo. Development 117, 283-291 (1993).
-
(1993)
Development
, vol.117
, pp. 283-291
-
-
Ingham, P.W.1
Hidalgo, A.2
-
31
-
-
0030989287
-
A role for the Wnt gene family in hematopoiesis: Expansion of multilineage progenitor cells
-
Austin, T. W., Solar, G. P., Ziegler, F. C., Liem, L. & Matthews, W. A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells. Blood 89, 3624-3635 (1997).
-
(1997)
Blood
, vol.89
, pp. 3624-3635
-
-
Austin, T.W.1
Solar, G.P.2
Ziegler, F.C.3
Liem, L.4
Matthews, W.5
-
32
-
-
0032212190
-
Role of members of the Wnt gene family in human hematopoiesis
-
Van Den Berg, D. J., Sharma, A. K., Bruno, E. & Hoffman, R. Role of members of the Wnt gene family in human hematopoiesis. Blood 92, 3189-3202 (1998).
-
(1998)
Blood
, vol.92
, pp. 3189-3202
-
-
Van Den Berg, D.J.1
Sharma, A.K.2
Bruno, E.3
Hoffman, R.4
-
33
-
-
0032972372
-
β-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion
-
Zhu, A. J. & Watt, F. M. β-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion. Development 126, 2285-2298 (1999).
-
(1999)
Development
, vol.126
, pp. 2285-2298
-
-
Zhu, A.J.1
Watt, F.M.2
-
34
-
-
0032567078
-
De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β-catenin in skin
-
Gat, U., DasGupta, R., Degenstein, L. & Fuchs, E. De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β-catenin in skin. Cell 95, 605-614 (1998).
-
(1998)
Cell
, vol.95
, pp. 605-614
-
-
Gat, U.1
DasGupta, R.2
Degenstein, L.3
Fuchs, E.4
-
35
-
-
0002770481
-
Depletion of epithelia stem-cell compartments in the small intestine of mice lacking Tcf-4
-
Korinek, V. et al. Depletion of epithelia stem-cell compartments in the small intestine of mice lacking Tcf-4. Nature Genet. 19, 1-5 (1998).
-
(1998)
Nature Genet.
, vol.19
, pp. 1-5
-
-
Korinek, V.1
-
36
-
-
18644373146
-
The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering, M. et al. The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 111, 241-250 (2002).
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
Van de Wetering, M.1
-
37
-
-
0037135177
-
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
-
Chenn, A. & Walsh, C. A. Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science 297, 365-369 (2002).
-
(2002)
Science
, vol.297
, pp. 365-369
-
-
Chenn, A.1
Walsh, C.A.2
-
38
-
-
18744398990
-
Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling
-
Kielman, M. F. et al. Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling. Nature Genet. 32, 594-605 (2002).
-
(2002)
Nature Genet.
, vol.32
, pp. 594-605
-
-
Kielman, M.F.1
-
39
-
-
0035907041
-
β-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
-
Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G. & Birchmeier, W. β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105, 533-545 (2001).
-
(2001)
Cell
, vol.105
, pp. 533-545
-
-
Huelsken, J.1
Vogel, R.2
Erdmann, B.3
Cotsarelis, G.4
Birchmeier, W.5
-
40
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya, T., Morrison, S. J., Clarke, M. F. & Weissman, I. L. Stem cells, cancer, and cancer stem cells. Nature 414, 105-111 (2001).
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
41
-
-
0034677173
-
The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of BCL-2 increases both their number and repopulation potential
-
Domen, J., Cheshier, S. H. & Weissman, I. L. The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of BCL-2 increases both their number and repopulation potential. J. Exp. Med. 191, 253-364 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 253-364
-
-
Domen, J.1
Cheshier, S.H.2
Weissman, I.L.3
-
42
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
Dull, T. et al. A third-generation lentivirus vector with a conditional packaging system. J. Virol. 72, 8463-8471 (1998).
-
(1998)
J. Virol.
, vol.72
, pp. 8463-8471
-
-
Dull, T.1
-
43
-
-
0030975671
-
-/- colon carcinoma
-
-/- colon carcinoma. Science 275, 1784-1787 (1997).
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
-
44
-
-
0034006464
-
High-fidelity mRNA amplification for gene profiling
-
Wang, E., Miller, L. D., Ohnmacht, G. A., Liu, E. T. & Marincola, F. M. High-fidelity mRNA amplification for gene profiling. Nature Biotechnol. 18, 457-459 (2000).
-
(2000)
Nature Biotechnol.
, vol.18
, pp. 457-459
-
-
Wang, E.1
Miller, L.D.2
Ohnmacht, G.A.3
Liu, E.T.4
Marincola, F.M.5
|