Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations

Oncogene

Volumn 24, Issue 18, 2005, Pages 3054-3058

  He, Biao ^a   Reguart, Noemi ^a,b   You, Liang ^a   Mazieres, Julien ^a,c   Xu, Zhidong ^a   Lee, Amie Y ^a   Mikami, Iwao ^a   McCormick, Frank ^a   Jablons, David M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^c INSTITUT CLAUDIUS REGAUD   (France)

Author keywords

Apoptosis; Colorectal cancer; Human; Wnt 1

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; DNA; DOCETAXEL; EPIDERMAL GROWTH FACTOR; FRIZZLED PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY WNT1; PROTEIN INHIBITOR; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT INHIBITORY FACTOR 1; WNT1 PROTEIN; SIGNAL PEPTIDE; WNT PROTEIN; WNT1 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL LEVEL; CLINICAL ARTICLE; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DNA METHYLATION; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; DRUG TARGETING; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; LOW DRUG DOSE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; COLORECTAL TUMOR; METABOLISM; MUTATION; PHYSIOLOGY;

APOPTOSIS; COLORECTAL NEOPLASMS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MUTATION; WNT PROTEINS; WNT1 PROTEIN;

EID: 18344377028     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208511     Document Type: Article

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