Suppressive regulatory T cell activity is potentiated by glycogen synthase kinase 3β inhibition

Journal of Biological Chemistry

Volumn 285, Issue 43, 2010, Pages 32852-32859

  Graham, Jay A ^a,b   Fray, Michael ^a,c   De Haseth, Stephanie ^a,d   Lee, Kang Mi ^a   Lian, Moh Moh ^a   Chase, Catharine M ^a   Madsen, Joren C ^a   Markmann, James ^a   Benichou, Gilles ^a   Colvin, Robert B ^a   Cosimi, A Benedict ^a   Deng, Shaoping ^a   Kim, James ^a   Alessandrini, Alessandro ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b GEORGETOWN UNIVERSITY HOSPITAL   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-APOPTOTIC PROTEIN; AUTOIMMUNE CONDITIONS; DEVELOPING STRATEGY; GLYCOGEN SYNTHASE KINASE-3; IMMUNE RESPONSE; MOUSE MODELS; SYSTEMIC ADMINISTRATION; T CELLS; TREG CELLS;

PHOSPHORYLATION;

ENZYME ACTIVITY;

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN BCL XL; TRANSCRIPTION FACTOR FOXP3;

ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; ENZYME INHIBITION; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE;

ANIMALS; AUTOIMMUNE DISEASES; BCL-X PROTEIN; BETA CATENIN; CELL SURVIVAL; ENZYME INHIBITORS; FORKHEAD TRANSCRIPTION FACTORS; GLYCOGEN SYNTHASE KINASE 3; IMMUNE TOLERANCE; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; PHOSPHORYLATION; T-LYMPHOCYTES, REGULATORY; TRANSPLANTATION, HOMOLOGOUS;

EID: 77958451155     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.150904     Document Type: Article

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