Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy

Nature Genetics

Volumn 32, Issue 2, 2002, Pages 326-330

  Robitaille, Johane ^a   MacDonald, Marcia L E ^b   Kaykas, Ajamete ^c   Sheldahl, Laird C ^c   Zeisler, Jutta ^b   Dubé, Marie Pierre ^b   Zhang, Lin Hua ^b   Singaraja, Roshni R ^b   Guernsey, Duane L ^a   Zheng, Binyou ^a   Siebert, Lee F ^d   Hoskin Mott, Ann ^a   Trese, Michael T ^e   Pimstone, Simon N ^b   Shastry, Barkur S ^f   Moon, Randall T ^c   Hayden, Michael R ^b,g   Paul Goldberg, Y ^b,g   Samuels, Mark E ^b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b Xenon Genetics Inc   (Canada)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

^e WILLIAM BEAUMONT HOSPITAL   (United States)

^f OAKLAND UNIVERSITY   (United States)

^g UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FRIZZLED 4 ACTIVATED CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE 2; PROTEIN; PROTEIN FZD4; PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN KINASE C; UNCLASSIFIED DRUG; WNT PROTEIN;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CALCIUM SIGNALING; CARCINOGENESIS; CASE REPORT; CELLULAR DISTRIBUTION; CHROMOSOME 11P; CHROMOSOME 11Q; CHROMOSOME MAP; CONTROLLED STUDY; EMBRYO; EYE DISEASE; FAMILIAL EXUDATIVE VITREORETINOPATHY; FEMALE; GENE LOCUS; GENE MUTATION; GENETIC LINKAGE; HETEROZYGOSITY; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; RETINA BLOOD VESSEL; STOP CODON; VASCULARIZATION; VITREORETINOPATHY; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; CHILD, PRESCHOOL; FEMALE; FRIZZLED RECEPTORS; GENETIC MARKERS; HAPLOTYPES; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; NEOVASCULARIZATION, PATHOLOGIC; PEDIGREE; POLYMORPHISM, GENETIC; PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RETINA; RETINAL DISEASES; RETINAL VESSELS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

ANIMALIA; XENOPUS LAEVIS;

EID: 0036789449     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng957     Document Type: Article

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