-
1
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers, H. Wnt/beta-catenin signaling in development and disease. Cell 127, 469-480 (2006).
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
2
-
-
41149174852
-
Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
-
Cole, M.F., Johnstone, S.E., Newman, J.J., Kagey, M.H. & Young, R.A. Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells. Genes Dev. 22, 746-755 (2008).
-
(2008)
Genes Dev
, vol.22
, pp. 746-755
-
-
Cole, M.F.1
Johnstone, S.E.2
Newman, J.J.3
Kagey, M.H.4
Young, R.A.5
-
3
-
-
33847214547
-
The intestinal Wnt/TCF signature
-
Van der Flier, L.G. et al. The intestinal Wnt/TCF signature. Gastroenterology 132, 628-632 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 628-632
-
-
Van der Flier, L.G.1
-
4
-
-
35648969554
-
Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells
-
Fevr, T., Robine, S., Louvard, D. & Huelsken, J. Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells. Mol. Cell. Biol. 27, 7551-7559 (2007).
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 7551-7559
-
-
Fevr, T.1
Robine, S.2
Louvard, D.3
Huelsken, J.4
-
5
-
-
0031848068
-
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
-
Korinek, V. et al. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat. Genet. 19, 379-383 (1998).
-
(1998)
Nat. Genet
, vol.19
, pp. 379-383
-
-
Korinek, V.1
-
6
-
-
34848895801
-
T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine
-
966-973
-
Muncan, V. et al. T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine. EMBO Rep. 8, 966-973 (2007).
-
(2007)
EMBO Rep
, vol.8
-
-
Muncan, V.1
-
7
-
-
34547924424
-
Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
-
Brack, A.S. et al. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 317, 807-810 (2007).
-
(2007)
Science
, vol.317
, pp. 807-810
-
-
Brack, A.S.1
-
8
-
-
34547908461
-
Augmented Wnt signaling in a mammalian model of accelerated aging
-
Liu, H. et al. Augmented Wnt signaling in a mammalian model of accelerated aging. Science 317, 803-806 (2007).
-
(2007)
Science
, vol.317
, pp. 803-806
-
-
Liu, H.1
-
9
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya, T. & Clevers, H. Wnt signalling in stem cells and cancer. Nature 434, 843-850 (2005).
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
10
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler, K.W. & Vogelstein, B. Lessons from hereditary colorectal cancer. Cell 87, 159-170 (1996).
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
11
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjoblom, T. et al. The consensus coding sequences of human breast and colorectal cancers. Science 314, 268-274 (2006).
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjoblom, T.1
-
12
-
-
33846193290
-
The many ways of Wnt in cancer
-
Polakis, P. The many ways of Wnt in cancer. Curr. Opin. Genet. Dev. 17, 45-51 (2007).
-
(2007)
Curr. Opin. Genet. Dev
, vol.17
, pp. 45-51
-
-
Polakis, P.1
-
13
-
-
33751318469
-
Monounsaturated fatty acid modification of Wnt protein: Its role in Wnt secretion
-
Takada, R. et al. Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. Dev. Cell 11, 791-801 (2006).
-
(2006)
Dev. Cell
, vol.11
, pp. 791-801
-
-
Takada, R.1
-
14
-
-
33947213491
-
Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling
-
Kurayoshi, M., Yamamoto, H., Izumi, S. & Kikuchi, A. Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling. Biochem. J. 402, 515-523 (2007).
-
(2007)
Biochem. J
, vol.402
, pp. 515-523
-
-
Kurayoshi, M.1
Yamamoto, H.2
Izumi, S.3
Kikuchi, A.4
-
15
-
-
0035860538
-
Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal
-
Chamoun, Z. et al. Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Science 293, 2080-2084 (2001).
-
(2001)
Science
, vol.293
, pp. 2080-2084
-
-
Chamoun, Z.1
-
16
-
-
44449107477
-
Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum
-
Abrami, L., Kunz, B., Iacovache, I. & van der Goot, F.G. Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 105, 5384-5389 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 5384-5389
-
-
Abrami, L.1
Kunz, B.2
Iacovache, I.3
van der Goot, F.G.4
-
17
-
-
2142790592
-
The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family
-
Tanaka, K., Okabayashi, K., Asashima, M., Perrimon, N. & Kadowaki, T. The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur. J. Biochem. 267, 4300-4311 (2000).
-
(2000)
Eur. J. Biochem
, vol.267
, pp. 4300-4311
-
-
Tanaka, K.1
Okabayashi, K.2
Asashima, M.3
Perrimon, N.4
Kadowaki, T.5
-
18
-
-
41549115361
-
Wnt/beta-catenin signaling: New (and old) players and new insights
-
Huang, H. & He, X. Wnt/beta-catenin signaling: new (and old) players and new insights. Curr. Opin. Cell Biol. 20, 119-125 (2008).
-
(2008)
Curr. Opin. Cell Biol
, vol.20
, pp. 119-125
-
-
Huang, H.1
He, X.2
-
19
-
-
0032891720
-
E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation
-
Orsulic, S., Huber, O., Aberle, H., Arnold, S. & Kemler, R. E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation. J. Cell Sci. 112, 1237-1245 (1999).
-
(1999)
J. Cell Sci
, vol.112
, pp. 1237-1245
-
-
Orsulic, S.1
Huber, O.2
Aberle, H.3
Arnold, S.4
Kemler, R.5
-
20
-
-
0036148208
-
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
-
Jho, E.H. et al. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol. Cell. Biol. 22, 1172-1183 (2002).
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 1172-1183
-
-
Jho, E.H.1
-
21
-
-
0036149985
-
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors
-
Lustig, B. et al. Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol. Cell. Biol. 22, 1184-1193 (2002).
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 1184-1193
-
-
Lustig, B.1
-
22
-
-
45849104800
-
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin
-
Cselenyi, C.S. et al. LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin. Proc. Natl. Acad. Sci. USA 105, 8032-8037 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 8032-8037
-
-
Cselenyi, C.S.1
-
23
-
-
33847177201
-
Distinct Wnt signaling pathways have opposing roles in appendage regeneration
-
Stoick-Cooper, C.L. et al. Distinct Wnt signaling pathways have opposing roles in appendage regeneration. Development 134, 479-489 (2007).
-
(2007)
Development
, vol.134
, pp. 479-489
-
-
Stoick-Cooper, C.L.1
-
24
-
-
29344463583
-
fgf20 is essential for initiating zebrafish fin regeneration
-
Whitehead, G.G., Makino, S., Lien, C.L. & Keating, M.T. fgf20 is essential for initiating zebrafish fin regeneration. Science 310, 1957-1960 (2005).
-
(2005)
Science
, vol.310
, pp. 1957-1960
-
-
Whitehead, G.G.1
Makino, S.2
Lien, C.L.3
Keating, M.T.4
-
25
-
-
37849013557
-
Transcriptome profile of human colorectal adenomas
-
Sabates-Bellver, J. et al. Transcriptome profile of human colorectal adenomas. Mol. Cancer Res. 5, 1263-1275 (2007).
-
(2007)
Mol. Cancer Res
, vol.5
, pp. 1263-1275
-
-
Sabates-Bellver, J.1
-
26
-
-
33751530490
-
Mining the Wnt pathway for cancer therapeutics
-
Barker, N. & Clevers, H. Mining the Wnt pathway for cancer therapeutics. Nat. Rev. Drug Discov. 5, 997-1014 (2006).
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
27
-
-
38849090670
-
Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
-
Yang, J., Brown, M.S., Liang, G., Grishin, N.V. & Goldstein, J.L. Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 132, 387-396 (2008).
-
(2008)
Cell
, vol.132
, pp. 387-396
-
-
Yang, J.1
Brown, M.S.2
Liang, G.3
Grishin, N.V.4
Goldstein, J.L.5
-
28
-
-
4243067196
-
The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway
-
Lee, E., Salic, A., Kruger, R., Heinrich, R. & Kirschner, M.W. The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol. 1, E10 (2003).
-
(2003)
PLoS Biol
, vol.1
-
-
Lee, E.1
Salic, A.2
Kruger, R.3
Heinrich, R.4
Kirschner, M.W.5
-
29
-
-
24944557032
-
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility
-
Shepard, J.L. et al. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proc. Natl. Acad. Sci. USA 102, 13194-13199 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13194-13199
-
-
Shepard, J.L.1
-
30
-
-
0034659909
-
Roles for Fgf signaling during zebrafish fin regeneration
-
Poss, K.D. et al. Roles for Fgf signaling during zebrafish fin regeneration. Dev. Biol. 222, 347-358 (2000).
-
(2000)
Dev. Biol
, vol.222
, pp. 347-358
-
-
Poss, K.D.1
|