Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1

Immunity

Volumn 33, Issue 2, 2010, Pages 229-240

  Zhou, Xinyuan ^a   Yu, Shuyang ^a   Zhao, Dong Mei ^a   Harty, John T ^a   Badovinac, Vladimir P ^a   Xue, Hai Hui ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Cellimmuno; Molimmuno

Indexed keywords

EOMESODERMIN; INTERLEUKIN 15; INTERLEUKIN 2 RECEPTOR BETA; PROTEIN BCL 2; TRANSCRIPTION FACTOR 7; WNT PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CYTOTOXICITY; EFFECTOR CELL; LISTERIOSIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BETA CATENIN; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; IMMUNOLOGIC MEMORY; INTERLEUKIN-15; LISTERIA MONOCYTOGENES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; PROTEIN BINDING; REGULATORY SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION; T CELL TRANSCRIPTION FACTOR 1; T-BOX DOMAIN PROTEINS; TRANSCRIPTION, GENETIC; WNT PROTEINS;

EID: 77955869484     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2010.08.002     Document Type: Article

References (52)

1. Badovinac V.P., Harty J.T. Manipulating the rate of memory CD8+ T cell generation after acute infection. J. Immunol. 2007, 179:53-63.
2. Badovinac V.P., Haring J.S., Harty J.T. Initial T cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T cell response to infection. Immunity 2007, 26:827-841.
3. Barber D.L., Wherry E.J., Ahmed R. Cutting edge: Rapid in vivo killing by memory CD8 T cells. J. Immunol. 2003, 171:27-31.
4. Berard M., Brandt K., Bulfone-Paus S., Tough D.F. IL-15 promotes the survival of naive and memory phenotype CD8+ T cells. J. Immunol. 2003, 170:5018-5026.
5. Bianchi T., Gasser S., Trumpp A., MacDonald H.R. c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis. Blood 2006, 107:3992-3999.
6. Cannarile M.A., Lind N.A., Rivera R., Sheridan A.D., Camfield K.A., Wu B.B., Cheung K.P., Ding Z., Goldrath A.W. Transcriptional regulator Id2 mediates CD8+ T cell immunity. Nat. Immunol. 2006, 7:1317-1325.
7. Cho B.K., Rao V.P., Ge Q., Eisen H.N., Chen J. Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells. J. Exp. Med. 2000, 192:549-556.
8. Gattinoni L., Zhong X.S., Palmer D.C., Ji Y., Hinrichs C.S., Yu Z., Wrzesinski C., Boni A., Cassard L., Garvin L.M., et al. Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells. Nat. Med. 2009, 15:808-813.
9. Goldrath A.W., Bogatzki L.Y., Bevan M.J. Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J. Exp. Med. 2000, 192:557-564.
10. Harty J.T., Badovinac V.P. Shaping and reshaping CD8+ T-cell memory. Nat. Rev. Immunol. 2008, 8:107-119.
11. He T.C., Sparks A.B., Rago C., Hermeking H., Zawel L., da Costa L.T., Morin P.J., Vogelstein B., Kinzler K.W. Identification of c-MYC as a target of the APC pathway. Science 1998, 281:1509-1512.
12. Hinrichs C.S., Spolski R., Paulos C.M., Gattinoni L., Kerstann K.W., Palmer D.C., Klebanoff C.A., Rosenberg S.A., Leonard W.J., Restifo N.P. IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy. Blood 2008, 111:5326-5333.
13. Huang da W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 2009, 4:44-57.
14. Ichii H., Sakamoto A., Kuroda Y., Tokuhisa T. Bcl6 acts as an amplifier for the generation and proliferative capacity of central memory CD8+ T cells. J. Immunol. 2004, 173:883-891.
15. Intlekofer A.M., Takemoto N., Wherry E.J., Longworth S.A., Northrup J.T., Palanivel V.R., Mullen A.C., Gasink C.R., Kaech S.M., Miller J.D., et al. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat. Immunol. 2005, 6:1236-1244.
16. Intlekofer A.M., Takemoto N., Kao C., Banerjee A., Schambach F., Northrop J.K., Shen H., Wherry E.J., Reiner S.L. Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells. J. Exp. Med. 2007, 204:2015-2021.
17. Ioannidis V., Beermann F., Clevers H., Held W. The beta-catenin-TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival. Nat. Immunol. 2001, 2:691-697.
18. Jabbari A., Harty J.T. Cutting edge: Differential self-peptide/MHC requirement for maintaining CD8 T cell function versus homeostatic proliferation. J. Immunol. 2005, 175:4829-4833.
19. Jeannet G., Scheller M., Scarpellino L., Duboux S., Gardiol N., Back J., Kuttler F., Malanchi I., Birchmeier W., Leutz A., et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood 2008, 111:142-149.
20. Jeannet G., Boudousquié C., Gardiol N., Kang J., Huelsken J., Held W. Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory. Proc. Natl. Acad. Sci. USA 2010, 107:9777-9782.
21. Jho E.H., Zhang T., Domon C., Joo C.K., Freund J.N., Costantini F. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol. Cell. Biol. 2002, 22:1172-1183.
22. Joshi N.S., Cui W., Chandele A., Lee H.K., Urso D.R., Hagman J., Gapin L., Kaech S.M. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 2007, 27:281-295.
23. Kaech S.M., Wherry E.J. Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. Immunity 2007, 27:393-405.
24. Kallies A., Xin A., Belz G.T., Nutt S.L. Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses. Immunity 2009, 31:283-295.
25. Lefrançois L., Marzo A.L. The descent of memory T-cell subsets. Nat. Rev. Immunol. 2006, 6:618-623.
26. Lehtonen A., Ahlfors H., Veckman V., Miettinen M., Lahesmaa R., Julkunen I. Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells. J. Leukoc. Biol. 2007, 82:710-720.
27. Lobov I.B., Rao S., Carroll T.J., Vallance J.E., Ito M., Ondr J.K., Kurup S., Glass D.A., Patel M.S., Shu W., et al. WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature 2005, 437:417-421.
28. Lustig B., Jerchow B., Sachs M., Weiler S., Pietsch T., Karsten U., van de Wetering M., Clevers H., Schlag P.M., Birchmeier W., Behrens J. Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol. Cell. Biol. 2002, 22:1184-1193.
29. Martins G., Calame K. Regulation and functions of Blimp-1 in T and B lymphocytes. Annu. Rev. Immunol. 2008, 26:133-169.
30. Masopust D., Vezys V., Marzo A.L., Lefrançois L. Preferential localization of effector memory cells in nonlymphoid tissue. Science 2001, 291:2413-2417.
31. Meijer L., Flajolet M., Greengard P. Pharmacological inhibitors of glycogen synthase kinase 3. Trends Pharmacol. Sci. 2004, 25:471-480.
32. Murali-Krishna K., Lau L.L., Sambhara S., Lemonnier F., Altman J., Ahmed R. Persistence of memory CD8 T cells in MHC class I-deficient mice. Science 1999, 286:1377-1381.
33. Okamura R.M., Sigvardsson M., Galceran J., Verbeek S., Clevers H., Grosschedl R. Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1. Immunity 1998, 8:11-20.
34. Prlic M., Lefrancois L., Jameson S.C. Multiple choices: Regulation of memory CD8 T cell generation and homeostasis by interleukin (IL)-7 and IL-15. J. Exp. Med. 2002, 195:F49-F52.
35. Rutishauser R.L., Martins G.A., Kalachikov S., Chandele A., Parish I.A., Meffre E., Jacob J., Calame K., Kaech S.M. Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. Immunity 2009, 31:296-308.
36. Sallusto F., Lenig D., Förster R., Lipp M., Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999, 401:708-712.
37. Schilham M.W., Wilson A., Moerer P., Benaissa-Trouw B.J., Cumano A., Clevers H.C. Critical involvement of Tcf-1 in expansion of thymocytes. J. Immunol. 1998, 161:3984-3991.
38. Schluns K.S., Lefrançois L. Cytokine control of memory T-cell development and survival. Nat. Rev. Immunol. 2003, 3:269-279.
39. Staal F.J., Weerkamp F., Baert M.R., van den Burg C.M., van Noort M., de Haas E.F., van Dongen J.J. Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion. J. Immunol. 2004, 172:1099-1108.
40. Staal F.J., Luis T.C., Tiemessen M.M. WNT signalling in the immune system: WNT is spreading its wings. Nat. Rev. Immunol. 2008, 8:581-593.
41. van de Wetering M., Clevers H. Sequence-specific interaction of the HMG box proteins TCF-1 and SRY occurs within the minor groove of a Watson-Crick double helix. EMBO J. 1992, 11:3039-3044.
42. Verbeek S., Izon D., Hofhuis F., Robanus-Maandag E., te Riele H., van de Wetering M., Oosterwegel M., Wilson A., MacDonald H.R., Clevers H. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature 1995, 374:70-74.
43. Wherry E.J., Teichgräber V., Becker T.C., Masopust D., Kaech S.M., Antia R., von Andrian U.H., Ahmed R. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 2003, 4:225-234.
44. Willert K., Brown J.D., Danenberg E., Duncan A.W., Weissman I.L., Reya T., Yates J.R., Nusse R. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 2003, 423:448-452.
45. Williams M.A., Bevan M.J. Effector and memory CTL differentiation. Annu. Rev. Immunol. 2007, 25:171-192.
46. Willinger T., Freeman T., Herbert M., Hasegawa H., McMichael A.J., Callan M.F. Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo. J. Immunol. 2006, 176:1439-1446.
47. Wu B., Crampton S.P., Hughes C.C. Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. Immunity 2007, 26:227-239.
48. Xie H., Huang Z., Sadim M.S., Sun Z. Stabilized beta-catenin extends thymocyte survival by up-regulating Bcl-xL. J. Immunol. 2005, 175:7981-7988.
49. Xu Y., Banerjee D., Huelsken J., Birchmeier W., Sen J.M. Deletion of beta-catenin impairs T cell development. Nat. Immunol. 2003, 4:1177-1182.
50. Yu Q., Sharma A., Oh S.Y., Moon H.G., Hossain M.Z., Salay T.M., Leeds K.E., Du H., Wu B., Waterman M.L., et al. T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma. Nat. Immunol. 2009, 10:992-999.
51. Yu S., Zhao D.M., Jothi R., Xue H.H. Critical requirement of GABPalpha for normal T cell development. J. Biol. Chem. 2010, 285:10179-10188.
52. Zhao D.M., Yu S., Zhou X., Haring J.S., Held W., Badovinac V.P., Harty J.T., Xue H.H. Constitutive activation of Wnt signaling favors generation of memory CD8 T cells. J. Immunol. 2010, 184:1191-1199.