-
1
-
-
0035857959
-
Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda
-
Gray RH, et al. Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda. Lancet 2001;357:1149-1153.
-
(2001)
Lancet
, vol.357
, pp. 1149-1153
-
-
Gray, R.H.1
-
3
-
-
0023099283
-
Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins
-
Gelderblom HR, Hausmann EH, Ozel M, Pauli G, Koch MA. Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins. Virology 1987;156:171-176.
-
(1987)
Virology
, vol.156
, pp. 171-176
-
-
Gelderblom, H.R.1
Hausmann, E.H.2
Ozel, M.3
Pauli, G.4
Koch, M.A.5
-
4
-
-
0347364638
-
Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions
-
Zhu P, et al. Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions. Proc Natl Acad Sci USA 2003;100:15812-15817.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15812-15817
-
-
Zhu, P.1
-
5
-
-
33745203490
-
Distribution and three-dimensional structure of AIDS virus envelope spikes
-
Zhu P, et al. Distribution and three-dimensional structure of AIDS virus envelope spikes. Nature 2006;441:847-852.
-
(2006)
Nature
, vol.441
, pp. 847-852
-
-
Zhu, P.1
-
6
-
-
0030970693
-
Core structure of gp41 from the HIV envelope glycoprotein
-
Chan DC, Fass D, Berger JM, Kim PS. Core structure of gp41 from the HIV envelope glycoprotein. Cell 1997;89:263-273.
-
(1997)
Cell
, vol.89
, pp. 263-273
-
-
Chan, D.C.1
Fass, D.2
Berger, J.M.3
Kim, P.S.4
-
7
-
-
57149107577
-
Cryoelectron tomography of HIV-1 envelope spikes: further evidence for tripod-like legs
-
Zhu P, Winkler H, Chertova E, Taylor KA, Roux KH. Cryoelectron tomography of HIV-1 envelope spikes: further evidence for tripod-like legs. PLoS Pathog 2008;4:e1000203.
-
(2008)
PLoS Pathog
, vol.4
-
-
Zhu, P.1
Winkler, H.2
Chertova, E.3
Taylor, K.A.4
Roux, K.H.5
-
8
-
-
51349162563
-
Molecular architecture of native HIV-1 gp120 trimers
-
Liu J, Bartesaghi A, Borgnia MJ, Sapiro G, Subramaniam S. Molecular architecture of native HIV-1 gp120 trimers. Nature 2008;455:109-113.
-
(2008)
Nature
, vol.455
, pp. 109-113
-
-
Liu, J.1
Bartesaghi, A.2
Borgnia, M.J.3
Sapiro, G.4
Subramaniam, S.5
-
9
-
-
78651241895
-
Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure
-
White TA, et al. Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure. PLoS Pathog 2010;6:e1001249.
-
(2010)
PLoS Pathog
, vol.6
-
-
White, T.A.1
-
10
-
-
78650426126
-
Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure
-
Wu SR, et al. Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure. Proc Natl Acad Sci USA 2010;107:18844-18849.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18844-18849
-
-
Wu, S.R.1
-
11
-
-
81255213876
-
Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography
-
White TA, et al. Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography. J Virol 2011;85:12114-12123.
-
(2011)
J Virol
, vol.85
, pp. 12114-12123
-
-
White, T.A.1
-
12
-
-
79960974710
-
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures
-
Harris A, et al. Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures. Proc Natl Acad Sci USA 2011;108:11440-11445.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 11440-11445
-
-
Harris, A.1
-
13
-
-
79955048174
-
Quaternary structures of HIV Env immunogen exhibit conformational vicissitudes and interface diminution elicited by ligand binding
-
Moscoso CG, et al. Quaternary structures of HIV Env immunogen exhibit conformational vicissitudes and interface diminution elicited by ligand binding. Proc Natl Acad Sci USA 2011;108:6091-6096.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 6091-6096
-
-
Moscoso, C.G.1
-
14
-
-
79952368717
-
Structural comparison of HIV-1 envelope spikes with and without the V1/V2 loop
-
Hu G, Liu J, Taylor KA, Roux KH. Structural comparison of HIV-1 envelope spikes with and without the V1/V2 loop. J Virol 2011;85:2741-2750.
-
(2011)
J Virol
, vol.85
, pp. 2741-2750
-
-
Hu, G.1
Liu, J.2
Taylor, K.A.3
Roux, K.H.4
-
15
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, Hendrickson WA. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 1998;393:648-659.
-
(1998)
Nature
, vol.393
, pp. 648-659
-
-
Kwong, P.D.1
Wyatt, R.2
Robinson, J.3
Sweet, R.W.4
Sodroski, J.5
Hendrickson, W.A.6
-
16
-
-
84859561617
-
Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops
-
Kwon YD, et al. Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc Natl Acad Sci USA 2012;109:5663-5668.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 5663-5668
-
-
Kwon, Y.D.1
-
17
-
-
83455254775
-
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
-
McLellan JS, et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature 2011;480:336-343.
-
(2011)
Nature
, vol.480
, pp. 336-343
-
-
McLellan, J.S.1
-
18
-
-
84864603281
-
Structural mechanism of trimeric HIV-1 envelope glycoprotein activation
-
Tran EE, et al. Structural mechanism of trimeric HIV-1 envelope glycoprotein activation. PLoS Pathog 2012;8:e1002797.
-
(2012)
PLoS Pathog
, vol.8
-
-
Tran, E.E.1
-
19
-
-
0037769964
-
The HIV Env-mediated fusion reaction
-
Gallo SA, et al. The HIV Env-mediated fusion reaction. Biochim Biophys Acta 2003;1614:36-50.
-
(2003)
Biochim Biophys Acta
, vol.1614
, pp. 36-50
-
-
Gallo, S.A.1
-
20
-
-
3042794175
-
Recent advances in understanding the molecular mechanisms of HIV-1 entry and fusion: revisiting current targets and considering new options for therapeutic intervention
-
Markovic I, Clouse KA. Recent advances in understanding the molecular mechanisms of HIV-1 entry and fusion: revisiting current targets and considering new options for therapeutic intervention. Curr HIV Res 2004;2:223-234.
-
(2004)
Curr HIV Res
, vol.2
, pp. 223-234
-
-
Markovic, I.1
Clouse, K.A.2
-
21
-
-
0030962291
-
Atomic structure of the ectodomain from HIV-1 gp41
-
Weissenhorn W, Dessen A, Harrison SC, Skehel JJ, Wiley DC. Atomic structure of the ectodomain from HIV-1 gp41. Nature 1997;387:426-430.
-
(1997)
Nature
, vol.387
, pp. 426-430
-
-
Weissenhorn, W.1
Dessen, A.2
Harrison, S.C.3
Skehel, J.J.4
Wiley, D.C.5
-
22
-
-
0031729823
-
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
-
Kilby JM, et al. Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat Med 1998;4:1302-1307.
-
(1998)
Nat Med
, vol.4
, pp. 1302-1307
-
-
Kilby, J.M.1
-
23
-
-
0034701058
-
Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides
-
Shu W, Liu J, Ji H, Radigen L, Jiang S, Lu M. Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides. Biochemistry 2000;39:1634-1642.
-
(2000)
Biochemistry
, vol.39
, pp. 1634-1642
-
-
Shu, W.1
Liu, J.2
Ji, H.3
Radigen, L.4
Jiang, S.5
Lu, M.6
-
24
-
-
0037069386
-
Short constrained peptides that inhibit HIV-1 entry
-
Sia SK, Carr PA, Cochran AG, Malashkevich VN, Kim PS. Short constrained peptides that inhibit HIV-1 entry. Proc Natl Acad Sci USA 2002;99:14664-14669.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14664-14669
-
-
Sia, S.K.1
Carr, P.A.2
Cochran, A.G.3
Malashkevich, V.N.4
Kim, P.S.5
-
25
-
-
0343365487
-
Role of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion
-
Munoz-Barroso I, Salzwedel K, Hunter E, Blumenthal R. Role of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion. J Virol 1999;73:6089-6092.
-
(1999)
J Virol
, vol.73
, pp. 6089-6092
-
-
Munoz-Barroso, I.1
Salzwedel, K.2
Hunter, E.3
Blumenthal, R.4
-
26
-
-
0033941573
-
Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1
-
Kuhmann SE, Platt EJ, Kozak SL, Kabat D. Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1. J Virol 2000;74:7005-7015.
-
(2000)
J Virol
, vol.74
, pp. 7005-7015
-
-
Kuhmann, S.E.1
Platt, E.J.2
Kozak, S.L.3
Kabat, D.4
-
28
-
-
25144500649
-
Stoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1
-
Yang X, Kurteva S, Ren X, Lee S, Sodroski J. Stoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1. J Virol 2005;79:12132-12147.
-
(2005)
J Virol
, vol.79
, pp. 12132-12147
-
-
Yang, X.1
Kurteva, S.2
Ren, X.3
Lee, S.4
Sodroski, J.5
-
29
-
-
36048944421
-
Modeling how many envelope glycoprotein trimers per virion participate in human immunodeficiency virus infectivity and its neutralization by antibody
-
Klasse PJ. Modeling how many envelope glycoprotein trimers per virion participate in human immunodeficiency virus infectivity and its neutralization by antibody. Virology 2007;369:245-262.
-
(2007)
Virology
, vol.369
, pp. 245-262
-
-
Klasse, P.J.1
-
30
-
-
59749083598
-
Estimating the stoichiometry of human immunodeficiency virus entry
-
Magnus C, Rusert P, Bonhoeffer S, Trkola A, Regoes RR. Estimating the stoichiometry of human immunodeficiency virus entry. J Virol 2009;83:1523-1531.
-
(2009)
J Virol
, vol.83
, pp. 1523-1531
-
-
Magnus, C.1
Rusert, P.2
Bonhoeffer, S.3
Trkola, A.4
Regoes, R.R.5
-
31
-
-
84859123277
-
Analysis of the subunit stoichiometries in viral entry
-
Magnus C, Regoes RR. Analysis of the subunit stoichiometries in viral entry. PLoS ONE 2012;7:e33441.
-
(2012)
PLoS ONE
, vol.7
-
-
Magnus, C.1
Regoes, R.R.2
-
32
-
-
0019890491
-
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
-
Wilson IA, Skehel JJ, Wiley DC. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution. Nature 1981;289:366-373.
-
(1981)
Nature
, vol.289
, pp. 366-373
-
-
Wilson, I.A.1
Skehel, J.J.2
Wiley, D.C.3
-
33
-
-
34250901022
-
Influenza virus pleiomorphy characterized by cryoelectron tomography
-
Harris A, et al. Influenza virus pleiomorphy characterized by cryoelectron tomography. Proc Natl Acad Sci USA 2006;103:19123-19127.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 19123-19127
-
-
Harris, A.1
-
34
-
-
0033783032
-
Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin
-
Skehel JJ, Wiley DC. Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annu Rev Biochem 2000;69:531-569.
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 531-569
-
-
Skehel, J.J.1
Wiley, D.C.2
-
35
-
-
0023915219
-
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid
-
Weis W, Brown JH, Cusack S, Paulson JC, Skehel JJ, Wiley DC. Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature 1988;333:426-431.
-
(1988)
Nature
, vol.333
, pp. 426-431
-
-
Weis, W.1
Brown, J.H.2
Cusack, S.3
Paulson, J.C.4
Skehel, J.J.5
Wiley, D.C.6
-
36
-
-
0024466223
-
Hemagglutinins from two influenza virus variants bind to sialic acid derivatives with millimolar dissociation constants: a 500-MHz proton nuclear magnetic resonance study
-
Sauter NK, et al. Hemagglutinins from two influenza virus variants bind to sialic acid derivatives with millimolar dissociation constants: a 500-MHz proton nuclear magnetic resonance study. Biochemistry 1989;28:8388-8396.
-
(1989)
Biochemistry
, vol.28
, pp. 8388-8396
-
-
Sauter, N.K.1
-
37
-
-
0028023726
-
Structure of influenza haemagglutinin at the pH of membrane fusion
-
Bullough PA, Hughson FM, Skehel JJ, Wiley DC. Structure of influenza haemagglutinin at the pH of membrane fusion. Nature 1994;371:37-43.
-
(1994)
Nature
, vol.371
, pp. 37-43
-
-
Bullough, P.A.1
Hughson, F.M.2
Skehel, J.J.3
Wiley, D.C.4
-
38
-
-
0019860749
-
Sequence relationships among the hemagglutinin genes of 12 subtypes of influenza A virus
-
Air GM. Sequence relationships among the hemagglutinin genes of 12 subtypes of influenza A virus. Proc Natl Acad Sci USA 1981;78:7639-7643.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 7639-7643
-
-
Air, G.M.1
-
39
-
-
0026175939
-
Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses
-
Nobusawa E, Aoyama T, Kato H, Suzuki Y, Tateno Y, Nakajima K. Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses. Virology 1991;182:475-485.
-
(1991)
Virology
, vol.182
, pp. 475-485
-
-
Nobusawa, E.1
Aoyama, T.2
Kato, H.3
Suzuki, Y.4
Tateno, Y.5
Nakajima, K.6
-
40
-
-
47049092748
-
The contents of the syringe
-
Salzberg S. The contents of the syringe. Nature 2008;454:160-161.
-
(2008)
Nature
, vol.454
, pp. 160-161
-
-
Salzberg, S.1
-
41
-
-
42149130934
-
Interim within-season estimate of the effectiveness of trivalent inactivated influenza vaccine-Marshfield, Wisconsin, 2007-08 influenza season
-
Centers for Disease Control and Prevention (CDC).
-
Centers for Disease Control and Prevention (CDC). Interim within-season estimate of the effectiveness of trivalent inactivated influenza vaccine-Marshfield, Wisconsin, 2007-08 influenza season. MMWR Morb Mortal Wkly Rep 2008;57:393-398.
-
(2008)
MMWR Morb Mortal Wkly Rep
, vol.57
, pp. 393-398
-
-
-
42
-
-
0022477122
-
Measurement of the mutation rates of animal viruses: influenza A virus and poliovirus type 1
-
Parvin JD, Moscona A, Pan WT, Leider JM, Palese P. Measurement of the mutation rates of animal viruses: influenza A virus and poliovirus type 1. J Virol 1986;59:377-383.
-
(1986)
J Virol
, vol.59
, pp. 377-383
-
-
Parvin, J.D.1
Moscona, A.2
Pan, W.T.3
Leider, J.M.4
Palese, P.5
-
43
-
-
0034625771
-
Timing the ancestor of the HIV-1 pandemic strains
-
Korber B, et al. Timing the ancestor of the HIV-1 pandemic strains. Science 2000;288:1789-1796.
-
(2000)
Science
, vol.288
, pp. 1789-1796
-
-
Korber, B.1
-
44
-
-
0037189323
-
Diversity considerations in HIV-1 vaccine selection
-
Gaschen B, et al. Diversity considerations in HIV-1 vaccine selection. Science 2002;296:2354-2360.
-
(2002)
Science
, vol.296
, pp. 2354-2360
-
-
Gaschen, B.1
-
45
-
-
38349081511
-
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus
-
Karlsson Hedestam GB, Fouchier RA, Phogat S, Burton DR, Sodroski J, Wyatt RT. The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus. Nat Rev Microbiol 2008;6:143-155.
-
(2008)
Nat Rev Microbiol
, vol.6
, pp. 143-155
-
-
Karlsson Hedestam, G.B.1
Fouchier, R.A.2
Phogat, S.3
Burton, D.R.4
Sodroski, J.5
Wyatt, R.T.6
-
46
-
-
0035162494
-
Evolutionary and immunological implications of contemporary HIV-1 variation
-
Korber B, Gaschen B, Yusim K, Thakallapally R, Kesmir C, Detours V. Evolutionary and immunological implications of contemporary HIV-1 variation. Br Med Bull 2001;58:19-42.
-
(2001)
Br Med Bull
, vol.58
, pp. 19-42
-
-
Korber, B.1
Gaschen, B.2
Yusim, K.3
Thakallapally, R.4
Kesmir, C.5
Detours, V.6
-
47
-
-
0028244285
-
An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization
-
Back NK, et al. An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization. Virology 1994;199:431-438.
-
(1994)
Virology
, vol.199
, pp. 431-438
-
-
Back, N.K.1
-
48
-
-
0035131175
-
Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants
-
Kolchinsky P, Kiprilov E, Sodroski J. Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants. J Virol 2001;75:2041-2050.
-
(2001)
J Virol
, vol.75
, pp. 2041-2050
-
-
Kolchinsky, P.1
Kiprilov, E.2
Sodroski, J.3
-
49
-
-
1842562419
-
N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies
-
McCaffrey RA, Saunders C, Hensel M, Stamatatos L. N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies. J Virol 2004;78:3279-3295.
-
(2004)
J Virol
, vol.78
, pp. 3279-3295
-
-
McCaffrey, R.A.1
Saunders, C.2
Hensel, M.3
Stamatatos, L.4
-
50
-
-
9944225582
-
Modified HIV envelope proteins with enhanced binding to neutralizing monoclonal antibodies
-
Kang SM, et al. Modified HIV envelope proteins with enhanced binding to neutralizing monoclonal antibodies. Virology 2005;331:20-32.
-
(2005)
Virology
, vol.331
, pp. 20-32
-
-
Kang, S.M.1
-
51
-
-
37849026069
-
Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses
-
Li Y, et al. Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses. J Virol 2008;82:638-651.
-
(2008)
J Virol
, vol.82
, pp. 638-651
-
-
Li, Y.1
-
52
-
-
70849114731
-
Glycans on influenza hemagglutinin affect receptor binding and immune response
-
Wang CC, et al. Glycans on influenza hemagglutinin affect receptor binding and immune response. Proc Natl Acad Sci USA 2009;106:18137-18142.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 18137-18142
-
-
Wang, C.C.1
-
53
-
-
77952001983
-
Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization
-
Binley JM, et al. Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization. J Virol 2010;84:5637-5655.
-
(2010)
J Virol
, vol.84
, pp. 5637-5655
-
-
Binley, J.M.1
-
54
-
-
79952713119
-
Glycan shielding of the influenza virus hemagglutinin contributes to immunopathology in mice
-
Wanzeck K, Boyd KL, McCullers JA. Glycan shielding of the influenza virus hemagglutinin contributes to immunopathology in mice. Am J Respir Crit Care Med 2011;183:767-773.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 767-773
-
-
Wanzeck, K.1
Boyd, K.L.2
McCullers, J.A.3
-
55
-
-
0023811767
-
Carbohydrates of human immunodeficiency virus. Structures of oligosaccharides linked to the envelope glycoprotein 120
-
Geyer H, Holschbach C, Hunsmann G, Schneider J. Carbohydrates of human immunodeficiency virus. Structures of oligosaccharides linked to the envelope glycoprotein 120. J Biol Chem 1988;263:11760-11767.
-
(1988)
J Biol Chem
, vol.263
, pp. 11760-11767
-
-
Geyer, H.1
Holschbach, C.2
Hunsmann, G.3
Schneider, J.4
-
56
-
-
0026451818
-
An O-linked carbohydrate neutralization epitope of HIV-1 gp 120 is expressed by HIV-1 env gene recombinant vaccinia virus
-
Hansen JE, Clausen H, Hu SL, Nielsen JO, Olofsson S. An O-linked carbohydrate neutralization epitope of HIV-1 gp 120 is expressed by HIV-1 env gene recombinant vaccinia virus. Arch Virol 1992;126:11-20.
-
(1992)
Arch Virol
, vol.126
, pp. 11-20
-
-
Hansen, J.E.1
Clausen, H.2
Hu, S.L.3
Nielsen, J.O.4
Olofsson, S.5
-
57
-
-
0027957921
-
Human immunodeficiency virus type 1 envelope glycoprotein is modified by O-linked oligosaccharides
-
Bernstein HB, Tucker SP, Hunter E, Schutzbach JS, Compans RW. Human immunodeficiency virus type 1 envelope glycoprotein is modified by O-linked oligosaccharides. J Virol 1994;68:463-468.
-
(1994)
J Virol
, vol.68
, pp. 463-468
-
-
Bernstein, H.B.1
Tucker, S.P.2
Hunter, E.3
Schutzbach, J.S.4
Compans, R.W.5
-
58
-
-
77956385205
-
Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens
-
Doores KJ, et al. Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens. Proc Natl Acad Sci USA 2010;107:13800-13805.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13800-13805
-
-
Doores, K.J.1
-
59
-
-
44649136618
-
Genetically destined potentials for N-linked glycosylation of influenza virus hemagglutinin
-
Igarashi M, Ito K, Kida H, Takada A. Genetically destined potentials for N-linked glycosylation of influenza virus hemagglutinin. Virology 2008;376:323-329.
-
(2008)
Virology
, vol.376
, pp. 323-329
-
-
Igarashi, M.1
Ito, K.2
Kida, H.3
Takada, A.4
-
60
-
-
79251480393
-
Glycosylation focuses sequence variation in the influenza A virus H1 hemagglutinin globular domain
-
Das SR, Puigbo P, Hensley SE, Hurt DE, Bennink JR, Yewdell JW. Glycosylation focuses sequence variation in the influenza A virus H1 hemagglutinin globular domain. PLoS Pathog 2010;6:e1001211.
-
(2010)
PLoS Pathog
, vol.6
-
-
Das, S.R.1
Puigbo, P.2
Hensley, S.E.3
Hurt, D.E.4
Bennink, J.R.5
Yewdell, J.W.6
-
61
-
-
0019432165
-
Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation
-
Wiley DC, Wilson IA, Skehel JJ. Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation. Nature 1981;289:373-378.
-
(1981)
Nature
, vol.289
, pp. 373-378
-
-
Wiley, D.C.1
Wilson, I.A.2
Skehel, J.J.3
-
62
-
-
0020738619
-
The structure and role of the carbohydrate moieties of influenza virus haemagglutinin
-
Wilson IA, Ladner RC, Skehel JJ, Wiley DC. The structure and role of the carbohydrate moieties of influenza virus haemagglutinin. Biochem Soc Trans 1983;11:145-147.
-
(1983)
Biochem Soc Trans
, vol.11
, pp. 145-147
-
-
Wilson, I.A.1
Ladner, R.C.2
Skehel, J.J.3
Wiley, D.C.4
-
63
-
-
77952969448
-
Cross-neutralization of 1918 and 2009 influenza viruses: role of glycans in viral evolution and vaccine design
-
Wei CJ, et al. Cross-neutralization of 1918 and 2009 influenza viruses: role of glycans in viral evolution and vaccine design. Sci Transl Med 2010;2:24ra21.
-
(2010)
Sci Transl Med
, vol.2
-
-
Wei, C.J.1
-
64
-
-
77951165843
-
Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus
-
Xu R, Ekiert DC, Krause JC, Hai R, Crowe JE, Jr., Wilson IA. Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus. Science 2010;328:357-360.
-
(2010)
Science
, vol.328
, pp. 357-360
-
-
Xu, R.1
Ekiert, D.C.2
Krause, J.C.3
Hai, R.4
Crowe Jr., J.E.5
Wilson, I.A.6
-
65
-
-
70349923632
-
Glycosylation site-specific analysis of clade C HIV-1 envelope proteins
-
Go EP, et al. Glycosylation site-specific analysis of clade C HIV-1 envelope proteins. J Proteome Res 2009;8:4231-4242.
-
(2009)
J Proteome Res
, vol.8
, pp. 4231-4242
-
-
Go, E.P.1
-
66
-
-
79961184231
-
Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry
-
Go EP, et al. Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry. J Virol 2011;85:8270-8284.
-
(2011)
J Virol
, vol.85
, pp. 8270-8284
-
-
Go, E.P.1
-
67
-
-
80051677678
-
The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade
-
Bonomelli C, et al. The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade. PLoS ONE 2011;6:e23521.
-
(2011)
PLoS ONE
, vol.6
-
-
Bonomelli, C.1
-
68
-
-
0032543555
-
The antigenic structure of the HIV gp120 envelope glycoprotein
-
Wyatt R, et al. The antigenic structure of the HIV gp120 envelope glycoprotein. Nature 1998;393:705-711.
-
(1998)
Nature
, vol.393
, pp. 705-711
-
-
Wyatt, R.1
-
69
-
-
0036181249
-
Viral persistance: HIV's strategies of immune system evasion
-
Johnson WE, Desrosiers RC. Viral persistance: HIV's strategies of immune system evasion. Annu Rev Med 2002;53:499-518.
-
(2002)
Annu Rev Med
, vol.53
, pp. 499-518
-
-
Johnson, W.E.1
Desrosiers, R.C.2
-
70
-
-
0141521564
-
Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1
-
Labrijn AF, et al. Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1. J Virol 2003;77:10557-10565.
-
(2003)
J Virol
, vol.77
, pp. 10557-10565
-
-
Labrijn, A.F.1
-
71
-
-
27744597054
-
Structure of a V3-containing HIV-1 gp120 core
-
Huang CC, et al. Structure of a V3-containing HIV-1 gp120 core. Science 2005;310:1025-1028.
-
(2005)
Science
, vol.310
, pp. 1025-1028
-
-
Huang, C.C.1
-
72
-
-
33144486096
-
Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1
-
Moore PL, et al. Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1. J Virol 2006;80:2515-2528.
-
(2006)
J Virol
, vol.80
, pp. 2515-2528
-
-
Moore, P.L.1
-
73
-
-
33845978962
-
Membrane association and epitope recognition by HIV-1 neutralizing anti-gp41 2F5 and 4E10 antibodies
-
Sanchez-Martinez S, Lorizate M, Katinger H, Kunert R, Nieva JL. Membrane association and epitope recognition by HIV-1 neutralizing anti-gp41 2F5 and 4E10 antibodies. AIDS Res Hum Retroviruses 2006;22:998-1006.
-
(2006)
AIDS Res Hum Retroviruses
, vol.22
, pp. 998-1006
-
-
Sanchez-Martinez, S.1
Lorizate, M.2
Katinger, H.3
Kunert, R.4
Nieva, J.L.5
-
74
-
-
38849090714
-
The C3-V4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection
-
Moore PL, et al. The C3-V4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection. J Virol 2008;82:1860-1869.
-
(2008)
J Virol
, vol.82
, pp. 1860-1869
-
-
Moore, P.L.1
-
75
-
-
56649083541
-
Humoral immunity to HIV-1: neutralisation and antibody effector functions
-
Willey S, Aasa-Chapman MM. Humoral immunity to HIV-1: neutralisation and antibody effector functions. Trends Microbiol 2008;16:596-604.
-
(2008)
Trends Microbiol
, vol.16
, pp. 596-604
-
-
Willey, S.1
Aasa-Chapman, M.M.2
-
76
-
-
9544239346
-
The consequence of passive administration of an anti-human immunodeficiency virus type 1 neutralizing monoclonal antibody before challenge of chimpanzees with a primary virus isolate
-
Conley AJ, et al. The consequence of passive administration of an anti-human immunodeficiency virus type 1 neutralizing monoclonal antibody before challenge of chimpanzees with a primary virus isolate. J Virol 1996;70:6751-6758.
-
(1996)
J Virol
, vol.70
, pp. 6751-6758
-
-
Conley, A.J.1
-
77
-
-
0037405488
-
Defining the protective antibody response for HIV-1
-
Mascola JR. Defining the protective antibody response for HIV-1. Curr Mol Med 2003;3:209-216.
-
(2003)
Curr Mol Med
, vol.3
, pp. 209-216
-
-
Mascola, J.R.1
-
78
-
-
68349160853
-
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
-
Hessell AJ, et al. Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques. Nat Med 2009;15:951-954.
-
(2009)
Nat Med
, vol.15
, pp. 951-954
-
-
Hessell, A.J.1
-
79
-
-
67249131966
-
Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
-
Hessell AJ, et al. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog 2009;5:e1000433.
-
(2009)
PLoS Pathog
, vol.5
-
-
Hessell, A.J.1
-
80
-
-
73949154006
-
Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L
-
Hessell AJ, et al. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L. J Virol 2009;84:1302-1313.
-
(2009)
J Virol
, vol.84
, pp. 1302-1313
-
-
Hessell, A.J.1
-
81
-
-
58149399396
-
Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies
-
Doria-Rose NA, et al. Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. J Virol 2009;83:188-199.
-
(2009)
J Virol
, vol.83
, pp. 188-199
-
-
Doria-Rose, N.A.1
-
82
-
-
58149487645
-
Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection
-
Sather DN, et al. Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection. J Virol 2009;83:757-769.
-
(2009)
J Virol
, vol.83
, pp. 757-769
-
-
Sather, D.N.1
-
83
-
-
67650453747
-
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm
-
Simek MD, et al. Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm. J Virol 2009;83:7337-7348.
-
(2009)
J Virol
, vol.83
, pp. 7337-7348
-
-
Simek, M.D.1
-
84
-
-
69149083668
-
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
-
Stamatatos L, Morris L, Burton DR, Mascola JR. Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine? Nat Med 2009;15:866-870.
-
(2009)
Nat Med
, vol.15
, pp. 866-870
-
-
Stamatatos, L.1
Morris, L.2
Burton, D.R.3
Mascola, J.R.4
-
85
-
-
0026655937
-
Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro
-
Barbas CF, 3rd, et al. Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro. Proc Natl Acad Sci USA 1992;89:9339-9343.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9339-9343
-
-
Barbas 3rd, C.F.1
-
86
-
-
0027223565
-
Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries
-
Barbas CF, 3rd, et al. Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries. J Mol Biol 1993;230:812-823.
-
(1993)
J Mol Biol
, vol.230
, pp. 812-823
-
-
Barbas 3rd, C.F.1
-
87
-
-
0028155283
-
Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization
-
Buchacher A, et al. Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization. AIDS Res Hum Retroviruses 1994;10:359-369.
-
(1994)
AIDS Res Hum Retroviruses
, vol.10
, pp. 359-369
-
-
Buchacher, A.1
-
88
-
-
12444291017
-
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition
-
Calarese DA, et al. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science 2003;300:2065-2071.
-
(2003)
Science
, vol.300
, pp. 2065-2071
-
-
Calarese, D.A.1
-
89
-
-
4544379899
-
Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
-
Ofek G, et al. Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope. J Virol 2004;78:10724-10737.
-
(2004)
J Virol
, vol.78
, pp. 10724-10737
-
-
Ofek, G.1
-
90
-
-
13844255333
-
Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41
-
Cardoso RM, et al. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity 2005;22:163-173.
-
(2005)
Immunity
, vol.22
, pp. 163-173
-
-
Cardoso, R.M.1
-
91
-
-
33847101745
-
Structural definition of a conserved neutralization epitope on HIV-1 gp120
-
Zhou T, et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature 2007;445:732-737.
-
(2007)
Nature
, vol.445
, pp. 732-737
-
-
Zhou, T.1
-
92
-
-
54849416088
-
Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site
-
Julien JP, Bryson S, Nieva JL, Pai EF. Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J Mol Biol 2008;384:377-392.
-
(2008)
J Mol Biol
, vol.384
, pp. 377-392
-
-
Julien, J.P.1
Bryson, S.2
Nieva, J.L.3
Pai, E.F.4
-
93
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Walker LM, et al. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 2009;326:285-289.
-
(2009)
Science
, vol.326
, pp. 285-289
-
-
Walker, L.M.1
-
94
-
-
80052942203
-
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
-
Wu X, et al. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science 2011;333:1593-1602.
-
(2011)
Science
, vol.333
, pp. 1593-1602
-
-
Wu, X.1
-
95
-
-
80052925616
-
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
-
Scheid JF, et al. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science 2011;333:1633-1637.
-
(2011)
Science
, vol.333
, pp. 1633-1637
-
-
Scheid, J.F.1
-
96
-
-
80052531336
-
Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses
-
Mouquet H, et al. Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PLoS ONE 2011;6:e24078.
-
(2011)
PLoS ONE
, vol.6
-
-
Mouquet, H.1
-
97
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Walker LM, et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature 2011;477:466-470.
-
(2011)
Nature
, vol.477
, pp. 466-470
-
-
Walker, L.M.1
-
98
-
-
72649097490
-
Mining the B cell repertoire for broadly neutralizing monoclonal antibodies to HIV-1
-
Kwong PD, Mascola JR, Nabel GJ. Mining the B cell repertoire for broadly neutralizing monoclonal antibodies to HIV-1. Cell Host Microbe 2009;6:292-294.
-
(2009)
Cell Host Microbe
, vol.6
, pp. 292-294
-
-
Kwong, P.D.1
Mascola, J.R.2
Nabel, G.J.3
-
99
-
-
80053146815
-
Vaccinology: precisely tuned antibodies nab HIV
-
Clapham PR, Lu S. Vaccinology: precisely tuned antibodies nab HIV. Nature 2011;477:416-417.
-
(2011)
Nature
, vol.477
, pp. 416-417
-
-
Clapham, P.R.1
Lu, S.2
-
101
-
-
84863774072
-
Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses
-
Burton DR, Poignard P, Stanfield RL, Wilson IA. Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science 2012;337:183-186.
-
(2012)
Science
, vol.337
, pp. 183-186
-
-
Burton, D.R.1
Poignard, P.2
Stanfield, R.L.3
Wilson, I.A.4
-
102
-
-
0024833055
-
Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda
-
Huse WD, et al. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science 1989;246:1275-1281.
-
(1989)
Science
, vol.246
, pp. 1275-1281
-
-
Huse, W.D.1
-
103
-
-
0027471177
-
A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains
-
Okuno Y, Isegawa Y, Sasao F, Ueda S. A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains. J Virol 1993;67:2552-2558.
-
(1993)
J Virol
, vol.67
, pp. 2552-2558
-
-
Okuno, Y.1
Isegawa, Y.2
Sasao, F.3
Ueda, S.4
-
104
-
-
77954943648
-
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
-
Zhou T, et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science 2010;329:811-817.
-
(2010)
Science
, vol.329
, pp. 811-817
-
-
Zhou, T.1
-
105
-
-
84870317596
-
Structure and design of broadly-neutralizing antibodies against HIV
-
doi:10.1007/s10059-012-0104-4.
-
Ryu SE, Hendrickson WA. Structure and design of broadly-neutralizing antibodies against HIV. Mol Cells 2012;doi:10.1007/s10059-012-0104-4.
-
(2012)
Mol Cells
-
-
Ryu, S.E.1
Hendrickson, W.A.2
-
106
-
-
70450182950
-
Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120
-
Chen L, et al. Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science 2009;326:1123-1127.
-
(2009)
Science
, vol.326
, pp. 1123-1127
-
-
Chen, L.1
-
107
-
-
82755184131
-
Increasing the potency and breadth of an HIV antibody by using structure-based rational design
-
Diskin R, et al. Increasing the potency and breadth of an HIV antibody by using structure-based rational design. Science 2011;334:1289-1293.
-
(2011)
Science
, vol.334
, pp. 1289-1293
-
-
Diskin, R.1
-
108
-
-
34247106331
-
An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10
-
Nelson JD, et al. An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10. J Virol 2007;81:4033-4043.
-
(2007)
J Virol
, vol.81
, pp. 4033-4043
-
-
Nelson, J.D.1
-
109
-
-
40849136223
-
The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design
-
Montero M, van Houten NE, Wang X, Scott JK. The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design. Microbiol Mol Biol Rev 2008;72:54-84.
-
(2008)
Microbiol Mol Biol Rev
, vol.72
, pp. 54-84
-
-
Montero, M.1
van Houten, N.E.2
Wang, X.3
Scott, J.K.4
-
110
-
-
79959616682
-
Targeting HIV-1 gp41 in close proximity to the membrane using antibody and other molecules
-
Gach JS, Leaman DP, Zwick MB. Targeting HIV-1 gp41 in close proximity to the membrane using antibody and other molecules. Curr Top Med Chem 2011;11:2997-3021.
-
(2011)
Curr Top Med Chem
, vol.11
, pp. 2997-3021
-
-
Gach, J.S.1
Leaman, D.P.2
Zwick, M.B.3
-
111
-
-
70350309664
-
Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications
-
Bryson S, Julien JP, Hynes RC, Pai EF. Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J Virol 2009;83:11862-11875.
-
(2009)
J Virol
, vol.83
, pp. 11862-11875
-
-
Bryson, S.1
Julien, J.P.2
Hynes, R.C.3
Pai, E.F.4
-
112
-
-
0032980413
-
A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity
-
Salzwedel K, West JT, Hunter E. A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity. J Virol 1999;73:2469-2480.
-
(1999)
J Virol
, vol.73
, pp. 2469-2480
-
-
Salzwedel, K.1
West, J.T.2
Hunter, E.3
-
113
-
-
34548170245
-
Functional links between the fusion peptide-proximal polar segment and membrane-proximal region of human immunodeficiency virus gp41 in distinct phases of membrane fusion
-
Bellamy-McIntyre AK, et al. Functional links between the fusion peptide-proximal polar segment and membrane-proximal region of human immunodeficiency virus gp41 in distinct phases of membrane fusion. J Biol Chem 2007;282:23104-23116.
-
(2007)
J Biol Chem
, vol.282
, pp. 23104-23116
-
-
Bellamy-McIntyre, A.K.1
-
114
-
-
0028813111
-
Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure
-
Poumbourios P, el Ahmar W, McPhee DA, Kemp BE. Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure. J Virol 1995;69:1209-1218.
-
(1995)
J Virol
, vol.69
, pp. 1209-1218
-
-
Poumbourios, P.1
El Ahmar, W.2
McPhee, D.A.3
Kemp, B.E.4
-
115
-
-
0033869815
-
Membrane interface-interacting sequences within the ectodomain of the human immunodeficiency virus type 1 envelope glycoprotein: putative role during viral fusion
-
Suarez T, Gallaher WR, Agirre A, Goni FM, Nieva JL. Membrane interface-interacting sequences within the ectodomain of the human immunodeficiency virus type 1 envelope glycoprotein: putative role during viral fusion. J Virol 2000;74:8038-8047.
-
(2000)
J Virol
, vol.74
, pp. 8038-8047
-
-
Suarez, T.1
Gallaher, W.R.2
Agirre, A.3
Goni, F.M.4
Nieva, J.L.5
-
116
-
-
0038418536
-
The pre-transmembrane region of the human immunodeficiency virus type-1 glycoprotein: a novel fusogenic sequence
-
Suarez T, Nir S, Goni FM, Saez-Cirion A, Nieva JL. The pre-transmembrane region of the human immunodeficiency virus type-1 glycoprotein: a novel fusogenic sequence. FEBS Lett 2000;477:145-149.
-
(2000)
FEBS Lett
, vol.477
, pp. 145-149
-
-
Suarez, T.1
Nir, S.2
Goni, F.M.3
Saez-Cirion, A.4
Nieva, J.L.5
-
117
-
-
0037077229
-
Sphingomyelin and cholesterol promote HIV-1 gp41 pretransmembrane sequence surface aggregation and membrane restructuring
-
Saez-Cirion A, et al. Sphingomyelin and cholesterol promote HIV-1 gp41 pretransmembrane sequence surface aggregation and membrane restructuring. J Biol Chem 2002;277:21776-21785.
-
(2002)
J Biol Chem
, vol.277
, pp. 21776-21785
-
-
Saez-Cirion, A.1
-
118
-
-
0035873475
-
Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1
-
Alfsen A, Iniguez P, Bouguyon E, Bomsel M. Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1. J Immunol 2001;166:6257-6265.
-
(2001)
J Immunol
, vol.166
, pp. 6257-6265
-
-
Alfsen, A.1
Iniguez, P.2
Bouguyon, E.3
Bomsel, M.4
-
119
-
-
0037067741
-
HIV-1 gp41 envelope residues 650-685 exposed on native virus act as a lectin to bind epithelial cell galactosyl ceramide
-
Alfsen A, Bomsel M. HIV-1 gp41 envelope residues 650-685 exposed on native virus act as a lectin to bind epithelial cell galactosyl ceramide. J Biol Chem 2002;277:25649-25659.
-
(2002)
J Biol Chem
, vol.277
, pp. 25649-25659
-
-
Alfsen, A.1
Bomsel, M.2
-
120
-
-
38049031709
-
The binding of HIV-1 gp41 membrane proximal domain to its mucosal receptor, galactosyl ceramide, is structure-dependent
-
Yu H, Alfsen A, Tudor D, Bomsel M. The binding of HIV-1 gp41 membrane proximal domain to its mucosal receptor, galactosyl ceramide, is structure-dependent. Cell Calcium 2008;43:73-82.
-
(2008)
Cell Calcium
, vol.43
, pp. 73-82
-
-
Yu, H.1
Alfsen, A.2
Tudor, D.3
Bomsel, M.4
-
121
-
-
0035859948
-
The membrane-proximal tryptophan-rich region of the HIV glycoprotein, gp41, forms a well-defined helix in dodecylphosphocholine micelles
-
Schibli DJ, Montelaro RC, Vogel HJ. The membrane-proximal tryptophan-rich region of the HIV glycoprotein, gp41, forms a well-defined helix in dodecylphosphocholine micelles. Biochemistry 2001;40:9570-9578.
-
(2001)
Biochemistry
, vol.40
, pp. 9570-9578
-
-
Schibli, D.J.1
Montelaro, R.C.2
Vogel, H.J.3
-
122
-
-
37849000389
-
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
-
Sun ZY, et al. HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane. Immunity 2008;28:52-63.
-
(2008)
Immunity
, vol.28
, pp. 52-63
-
-
Sun, Z.Y.1
-
123
-
-
69249220320
-
A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies
-
Pejchal R, et al. A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies. J Virol 2009;83:8451-8462.
-
(2009)
J Virol
, vol.83
, pp. 8451-8462
-
-
Pejchal, R.1
-
124
-
-
67049156802
-
Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface
-
Song L, et al. Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface. Proc Natl Acad Sci USA 2009;106:9057-9062.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9057-9062
-
-
Song, L.1
-
125
-
-
80555131011
-
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization
-
Kim M, et al. Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization. Nat Struct Mol Biol 2011;18:1235-1243.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 1235-1243
-
-
Kim, M.1
-
126
-
-
84055181327
-
Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
-
Walker LM, et al. Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque. Proc Natl Acad Sci USA 2011;108:20125-20129.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20125-20129
-
-
Walker, L.M.1
-
127
-
-
84863115983
-
High-mannose glycan-dependent epitopes are frequently targeted in broad neutralizing antibody responses during human immunodeficiency virus type 1 infection
-
Lavine CL, Lao S, Montefiori DC, Haynes BF, Sodroski JG, Yang X. High-mannose glycan-dependent epitopes are frequently targeted in broad neutralizing antibody responses during human immunodeficiency virus type 1 infection. J Virol 2012;86:2153-2164.
-
(2012)
J Virol
, vol.86
, pp. 2153-2164
-
-
Lavine, C.L.1
Lao, S.2
Montefiori, D.C.3
Haynes, B.F.4
Sodroski, J.G.5
Yang, X.6
-
128
-
-
0025292252
-
Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells
-
Leonard CK, Spellman MW, Riddle L, Harris RJ, Thomas JN, Gregory TJ. Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. J Biol Chem 1990;265:10373-10382.
-
(1990)
J Biol Chem
, vol.265
, pp. 10373-10382
-
-
Leonard, C.K.1
Spellman, M.W.2
Riddle, L.3
Harris, R.J.4
Thomas, J.N.5
Gregory, T.J.6
-
129
-
-
77951988965
-
Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function
-
Eggink D, et al. Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function. Virology 2010;401:236-247.
-
(2010)
Virology
, vol.401
, pp. 236-247
-
-
Eggink, D.1
-
130
-
-
18244422922
-
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1->2 mannose residues on the outer face of gp120
-
Scanlan CN, et al. The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1->2 mannose residues on the outer face of gp120. J Virol 2002;76:7306-7321.
-
(2002)
J Virol
, vol.76
, pp. 7306-7321
-
-
Scanlan, C.N.1
-
131
-
-
0023449237
-
Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine
-
Walker BD, et al. Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine. Proc Natl Acad Sci USA 1987;84:8120-8124.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 8120-8124
-
-
Walker, B.D.1
-
132
-
-
0034598905
-
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
-
Geijtenbeek TB, et al. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 2000;100:587-597.
-
(2000)
Cell
, vol.100
, pp. 587-597
-
-
Geijtenbeek, T.B.1
-
133
-
-
84860723906
-
Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design
-
Bonsignori M, et al. Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design. J Virol 2012;86:4688-4692.
-
(2012)
J Virol
, vol.86
, pp. 4688-4692
-
-
Bonsignori, M.1
-
134
-
-
82255179322
-
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield
-
Pejchal R, et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science 2011;334:1097-1103.
-
(2011)
Science
, vol.334
, pp. 1097-1103
-
-
Pejchal, R.1
-
135
-
-
65549114651
-
Efficient recovery of high-affinity antibodies from a single-chain Fab yeast display library
-
Walker LM, Bowley DR, Burton DR. Efficient recovery of high-affinity antibodies from a single-chain Fab yeast display library. J Mol Biol 2009;389:365-375.
-
(2009)
J Mol Biol
, vol.389
, pp. 365-375
-
-
Walker, L.M.1
Bowley, D.R.2
Burton, D.R.3
-
136
-
-
77954912140
-
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1
-
Pejchal R, et al. Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1. Proc Natl Acad Sci USA 2010;107:11483-11488.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 11483-11488
-
-
Pejchal, R.1
-
137
-
-
77954982131
-
Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1
-
Pancera M, et al. Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1. J Virol 2010;84:8098-8110.
-
(2010)
J Virol
, vol.84
, pp. 8098-8110
-
-
Pancera, M.1
-
138
-
-
0020416123
-
The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype)
-
Caton AJ, Brownlee GG, Yewdell JW, Gerhard W. The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype). Cell 1982;31:417-427.
-
(1982)
Cell
, vol.31
, pp. 417-427
-
-
Caton, A.J.1
Brownlee, G.G.2
Yewdell, J.W.3
Gerhard, W.4
-
139
-
-
80052184942
-
Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin
-
Whittle JR, et al. Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin. Proc Natl Acad Sci USA 2011;108:14216-14221.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 14216-14221
-
-
Whittle, J.R.1
-
140
-
-
84866953140
-
Cross-neutralization of influenza A viruses mediated by a single antibody loop into the receptor binding site
-
2012;doi:10.1038/nature11414.
-
Ekiert DC, et al. Cross-neutralization of influenza A viruses mediated by a single antibody loop into the receptor binding site. Nature, 2012;doi:10.1038/nature11414.
-
Nature
-
-
Ekiert, D.C.1
-
141
-
-
64949164763
-
High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies
-
Liao HX, et al. High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies. J Virol Methods 2009;158:171-179.
-
(2009)
J Virol Methods
, vol.158
, pp. 171-179
-
-
Liao, H.X.1
-
142
-
-
84859510667
-
Broadly neutralizing antibodies against influenza virus and prospects for universal therapies
-
Ekiert DC, Wilson IA. Broadly neutralizing antibodies against influenza virus and prospects for universal therapies. Curr Opin Virol 2012;2:134-141.
-
(2012)
Curr Opin Virol
, vol.2
, pp. 134-141
-
-
Ekiert, D.C.1
Wilson, I.A.2
-
143
-
-
58049198443
-
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells
-
Throsby M, et al. Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells. PLoS ONE 2008;3:e3942.
-
(2008)
PLoS ONE
, vol.3
-
-
Throsby, M.1
-
144
-
-
43149109969
-
Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies
-
Kashyap AK, et al. Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies. Proc Natl Acad Sci USA 2008;105:5986-5991.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 5986-5991
-
-
Kashyap, A.K.1
-
145
-
-
64849114224
-
Antibody recognition of a highly conserved influenza virus epitope
-
Ekiert DC, et al. Antibody recognition of a highly conserved influenza virus epitope. Science 2009;324:246-251.
-
(2009)
Science
, vol.324
, pp. 246-251
-
-
Ekiert, D.C.1
-
146
-
-
62049083943
-
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
-
Sui J, et al. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol 2009;16:265-273.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 265-273
-
-
Sui, J.1
-
147
-
-
77951876927
-
Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine
-
Corti D, et al. Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine. J Clin Invest 2010;120:1663-1673.
-
(2010)
J Clin Invest
, vol.120
, pp. 1663-1673
-
-
Corti, D.1
-
148
-
-
78651488739
-
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection
-
Wrammert J, et al. Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection. J Exp Med 2011;208:181-193.
-
(2011)
J Exp Med
, vol.208
, pp. 181-193
-
-
Wrammert, J.1
-
149
-
-
77956119219
-
Induction of broadly neutralizing H1N1 influenza antibodies by vaccination
-
Wei CJ, et al. Induction of broadly neutralizing H1N1 influenza antibodies by vaccination. Science 2010;329:1060-1064.
-
(2010)
Science
, vol.329
, pp. 1060-1064
-
-
Wei, C.J.1
-
150
-
-
80051635697
-
A highly conserved neutralizing epitope on group 2 influenza A viruses
-
Ekiert DC, et al. A highly conserved neutralizing epitope on group 2 influenza A viruses. Science 2011;333:843-850.
-
(2011)
Science
, vol.333
, pp. 843-850
-
-
Ekiert, D.C.1
-
151
-
-
80051670323
-
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
-
Corti D, et al. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science 2011;333:850-856.
-
(2011)
Science
, vol.333
, pp. 850-856
-
-
Corti, D.1
-
152
-
-
84866122029
-
Highly conserved protective epitopes on influenza B viruses
-
Dreyfus C, et al. Highly conserved protective epitopes on influenza B viruses. Science 2012;337:1343-1348.
-
(2012)
Science
, vol.337
, pp. 1343-1348
-
-
Dreyfus, C.1
-
153
-
-
65749107719
-
HIV-1 and influenza antibodies: seeing antigens in new ways
-
Kwong PD, Wilson IA. HIV-1 and influenza antibodies: seeing antigens in new ways. Nat Immunol 2009;10:573-578.
-
(2009)
Nat Immunol
, vol.10
, pp. 573-578
-
-
Kwong, P.D.1
Wilson, I.A.2
-
154
-
-
0036063659
-
An antibody that prevents the hemagglutinin low pH fusogenic transition
-
Barbey-Martin C, et al. An antibody that prevents the hemagglutinin low pH fusogenic transition. Virology 2002;294:70-74.
-
(2002)
Virology
, vol.294
, pp. 70-74
-
-
Barbey-Martin, C.1
-
155
-
-
66149132686
-
Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10
-
Klein JS, Gnanapragasam PN, Galimidi RP, Foglesong CP, West AP, Jr., Bjorkman PJ. Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10. Proc Natl Acad Sci USA 2009;106:7385-7390.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7385-7390
-
-
Klein, J.S.1
Gnanapragasam, P.N.2
Galimidi, R.P.3
Foglesong, C.P.4
West Jr., A.P.5
Bjorkman, P.J.6
-
156
-
-
77957355961
-
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
-
Mouquet H, et al. Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation. Nature 2010;467:591-595.
-
(2010)
Nature
, vol.467
, pp. 591-595
-
-
Mouquet, H.1
-
157
-
-
0019065845
-
Carbohydrate composition of the oligosaccharide units of the haemagglutinin from the Hong Kong influenza virus A/Memphis/102/72
-
Ward CW, Gleeson PA, Dopheide TA. Carbohydrate composition of the oligosaccharide units of the haemagglutinin from the Hong Kong influenza virus A/Memphis/102/72. Biochem J 1980;189:649-652.
-
(1980)
Biochem J
, vol.189
, pp. 649-652
-
-
Ward, C.W.1
Gleeson, P.A.2
Dopheide, T.A.3
-
158
-
-
0031041235
-
The glycosylation of the influenza A virus hemagglutinin by mammalian cells. A site-specific study
-
Mir-Shekari SY, Ashford DA, Harvey DJ, Dwek RA, Schulze IT. The glycosylation of the influenza A virus hemagglutinin by mammalian cells. A site-specific study. J Biol Chem 1997;272:4027-4036.
-
(1997)
J Biol Chem
, vol.272
, pp. 4027-4036
-
-
Mir-Shekari, S.Y.1
Ashford, D.A.2
Harvey, D.J.3
Dwek, R.A.4
Schulze, I.T.5
-
159
-
-
33846172297
-
Rational modifications of HIV-1 envelope glycoproteins for immunogen design
-
Phogat S, Wyatt R. Rational modifications of HIV-1 envelope glycoproteins for immunogen design. Curr Pharm Des 2007;13:213-227.
-
(2007)
Curr Pharm Des
, vol.13
, pp. 213-227
-
-
Phogat, S.1
Wyatt, R.2
-
160
-
-
77953543379
-
Rational antibody-based HIV-1 vaccine design: current approaches and future directions
-
Walker LM, Burton DR. Rational antibody-based HIV-1 vaccine design: current approaches and future directions. Curr Opin Immunol 2010;22:358-366.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 358-366
-
-
Walker, L.M.1
Burton, D.R.2
-
161
-
-
67249085575
-
Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site
-
Dey B, et al. Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site. PLoS Pathog 2009;5:e1000445.
-
(2009)
PLoS Pathog
, vol.5
-
-
Dey, B.1
-
162
-
-
77956247505
-
Design of a non-glycosylated outer domain-derived HIV-1 gp120 immunogen that binds to CD4 and induces neutralizing antibodies
-
Bhattacharyya S, et al. Design of a non-glycosylated outer domain-derived HIV-1 gp120 immunogen that binds to CD4 and induces neutralizing antibodies. J Biol Chem 2010;285:27100-27110.
-
(2010)
J Biol Chem
, vol.285
, pp. 27100-27110
-
-
Bhattacharyya, S.1
-
163
-
-
80054836686
-
Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold
-
Azoitei ML, et al. Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold. Science 2011;334:373-376.
-
(2011)
Science
, vol.334
, pp. 373-376
-
-
Azoitei, M.L.1
-
164
-
-
82455192354
-
Improving immunogenicity of HIV-1 envelope gp120 by glycan removal and immune complex formation
-
Kumar R, Tuen M, Li H, Tse DB, Hioe CE. Improving immunogenicity of HIV-1 envelope gp120 by glycan removal and immune complex formation. Vaccine 2011;29:9064-9074.
-
(2011)
Vaccine
, vol.29
, pp. 9064-9074
-
-
Kumar, R.1
Tuen, M.2
Li, H.3
Tse, D.B.4
Hioe, C.E.5
-
165
-
-
84855433610
-
An engineered mutant of HIV-1 gp120 formulated with adjuvant Quil A promotes elicitation of antibody responses overlapping the CD4-binding site
-
Ahmed FK, Clark BE, Burton DR, Pantophlet R. An engineered mutant of HIV-1 gp120 formulated with adjuvant Quil A promotes elicitation of antibody responses overlapping the CD4-binding site. Vaccine 2012;30:922-930.
-
(2012)
Vaccine
, vol.30
, pp. 922-930
-
-
Ahmed, F.K.1
Clark, B.E.2
Burton, D.R.3
Pantophlet, R.4
-
166
-
-
84863788697
-
Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers
-
Depetris RS, et al. Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers. J Biol Chem 2012;287:24239-24254.
-
(2012)
J Biol Chem
, vol.287
, pp. 24239-24254
-
-
Depetris, R.S.1
-
167
-
-
78149242586
-
Elicitation of structure-specific antibodies by epitope scaffolds
-
Ofek G, et al. Elicitation of structure-specific antibodies by epitope scaffolds. Proc Natl Acad Sci USA 2010;107:17880-17887.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 17880-17887
-
-
Ofek, G.1
-
168
-
-
82555168289
-
Structure-based design of a protein immunogen that displays an HIV-1 gp41 neutralizing epitope
-
Stanfield RL, Julien JP, Pejchal R, Gach JS, Zwick MB, Wilson IA. Structure-based design of a protein immunogen that displays an HIV-1 gp41 neutralizing epitope. J Mol Biol 2011;414:460-476.
-
(2011)
J Mol Biol
, vol.414
, pp. 460-476
-
-
Stanfield, R.L.1
Julien, J.P.2
Pejchal, R.3
Gach, J.S.4
Zwick, M.B.5
Wilson, I.A.6
-
169
-
-
84855258847
-
Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope
-
Azoitei ML, et al. Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope. J Mol Biol 2012;415:175-192.
-
(2012)
J Mol Biol
, vol.415
, pp. 175-192
-
-
Azoitei, M.L.1
-
170
-
-
73949133588
-
Role of HIV membrane in neutralization by two broadly neutralizing antibodies
-
Alam SM, et al. Role of HIV membrane in neutralization by two broadly neutralizing antibodies. Proc Natl Acad Sci USA 2009;106:20234-20239.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20234-20239
-
-
Alam, S.M.1
-
171
-
-
77649132440
-
Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region
-
Ofek G, et al. Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region. J Virol 2010;84:2955-2962.
-
(2010)
J Virol
, vol.84
, pp. 2955-2962
-
-
Ofek, G.1
-
172
-
-
73849143129
-
Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity
-
Xu H, et al. Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity. J Virol 2010;84:1076-1088.
-
(2010)
J Virol
, vol.84
, pp. 1076-1088
-
-
Xu, H.1
-
173
-
-
77950803157
-
Ablation of the complementarity-determining region H3 apex of the anti-HIV-1 broadly neutralizing antibody 2F5 abrogates neutralizing capacity without affecting core epitope binding
-
Julien JP, et al. Ablation of the complementarity-determining region H3 apex of the anti-HIV-1 broadly neutralizing antibody 2F5 abrogates neutralizing capacity without affecting core epitope binding. J Virol 2010;84:4136-4147.
-
(2010)
J Virol
, vol.84
, pp. 4136-4147
-
-
Julien, J.P.1
-
174
-
-
84864621158
-
Structure-guided alterations of the gp41-directed HIV-1 broadly neutralizing antibody 2F5 reveal new properties regarding its neutralizing function
-
Guenaga J, Wyatt RT. Structure-guided alterations of the gp41-directed HIV-1 broadly neutralizing antibody 2F5 reveal new properties regarding its neutralizing function. PLoS Pathog 2012;8:e1002806.
-
(2012)
PLoS Pathog
, vol.8
-
-
Guenaga, J.1
Wyatt, R.T.2
-
175
-
-
45749122331
-
An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies
-
Luallen RJ, et al. An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies. J Virol 2008;82:6447-6457.
-
(2008)
J Virol
, vol.82
, pp. 6447-6457
-
-
Luallen, R.J.1
-
176
-
-
45749138808
-
A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120
-
Astronomo RD, et al. A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120. J Virol 2008;82:6359-6368.
-
(2008)
J Virol
, vol.82
, pp. 6359-6368
-
-
Astronomo, R.D.1
-
177
-
-
55249109998
-
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens
-
Dunlop DC, et al. Antigenic mimicry of the HIV envelope by AIDS-associated pathogens. AIDS 2008;22:2214-2217.
-
(2008)
AIDS
, vol.22
, pp. 2214-2217
-
-
Dunlop, D.C.1
-
178
-
-
65349132918
-
A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN
-
Luallen RJ, et al. A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN. J Virol 2009;83:4861-4870.
-
(2009)
J Virol
, vol.83
, pp. 4861-4870
-
-
Luallen, R.J.1
-
179
-
-
77956366187
-
Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans
-
Dunlop DC, et al. Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans. Glycobiology 2010;20:812-823.
-
(2010)
Glycobiology
, vol.20
, pp. 812-823
-
-
Dunlop, D.C.1
-
180
-
-
78049254402
-
A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity
-
Doores KJ, et al. A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proc Natl Acad Sci USA 2010;107:17107-17112.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 17107-17112
-
-
Doores, K.J.1
-
181
-
-
77957201600
-
Very few substitutions in a germ line antibody are required to initiate significant domain exchange
-
Huber M, et al. Very few substitutions in a germ line antibody are required to initiate significant domain exchange. J Virol 2010;84:10700-10707.
-
(2010)
J Virol
, vol.84
, pp. 10700-10707
-
-
Huber, M.1
-
182
-
-
84862777880
-
Characterization of germline antibody libraries from human umbilical cord blood and selection of monoclonal antibodies to viral envelope glycoproteins: implications for mechanisms of immune evasion and design of vaccine immunogens
-
Chen W, Streaker ED, Russ DE, Feng Y, Prabakaran P, Dimitrov DS. Characterization of germline antibody libraries from human umbilical cord blood and selection of monoclonal antibodies to viral envelope glycoproteins: implications for mechanisms of immune evasion and design of vaccine immunogens. Biochem Biophys Res Commun 2012;417:1164-1169.
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 1164-1169
-
-
Chen, W.1
Streaker, E.D.2
Russ, D.E.3
Feng, Y.4
Prabakaran, P.5
Dimitrov, D.S.6
-
183
-
-
84860759632
-
B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study
-
Haynes BF, Kelsoe G, Harrison SC, Kepler TB. B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nat Biotechnol 2012;30:423-433.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 423-433
-
-
Haynes, B.F.1
Kelsoe, G.2
Harrison, S.C.3
Kepler, T.B.4
-
184
-
-
84864363185
-
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120
-
West AP, Jr., Diskin R, Nussenzweig MC, Bjorkman PJ. Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120. Proc Natl Acad Sci USA 2012;109:E2083-E2090.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
-
-
West Jr., A.P.1
Diskin, R.2
Nussenzweig, M.C.3
Bjorkman, P.J.4
-
185
-
-
78649953803
-
Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes
-
Wang TT, et al. Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes. Proc Natl Acad Sci USA 2010;107:18979-18984.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18979-18984
-
-
Wang, T.T.1
-
186
-
-
79952140653
-
Influenza virus vaccine based on the conserved hemagglutinin stalk domain
-
Steel J, et al. Influenza virus vaccine based on the conserved hemagglutinin stalk domain. MBio 2010;1:e000018-10.
-
(2010)
MBio
, vol.1
-
-
Steel, J.1
-
187
-
-
84863115945
-
Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses
-
Pica N, et al. Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses. Proc Natl Acad Sci USA 2012;109:2573-2578.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2573-2578
-
-
Pica, N.1
-
188
-
-
84861325359
-
Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes
-
Hai R, et al. Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes. J Virol 2012;86:5774-5781.
-
(2012)
J Virol
, vol.86
, pp. 5774-5781
-
-
Hai, R.1
-
189
-
-
79956017135
-
Computational design of proteins targeting the conserved stem region of influenza hemagglutinin
-
Fleishman SJ, et al. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science 2011;332:816-821.
-
(2011)
Science
, vol.332
, pp. 816-821
-
-
Fleishman, S.J.1
-
190
-
-
84862025262
-
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
-
Whitehead TA, et al. Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing. Nat Biotechnol 2012;30:543-548.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 543-548
-
-
Whitehead, T.A.1
-
191
-
-
80053474133
-
A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin
-
Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Basler CF, Crowe JE, Jr.. A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. J Virol 2011;85:10905-10908.
-
(2011)
J Virol
, vol.85
, pp. 10905-10908
-
-
Krause, J.C.1
Tsibane, T.2
Tumpey, T.M.3
Huffman, C.J.4
Basler, C.F.5
Crowe Jr., J.E.6
-
192
-
-
80053557269
-
Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence
-
Krause JC, et al. Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence. J Immunol 2011;187:3704-3711.
-
(2011)
J Immunol
, vol.187
, pp. 3704-3711
-
-
Krause, J.C.1
-
193
-
-
84863568230
-
Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses
-
Krause JC, et al. Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses. J Virol 2012;86:6334-6340.
-
(2012)
J Virol
, vol.86
, pp. 6334-6340
-
-
Krause, J.C.1
-
194
-
-
75749120153
-
Monoclonal antibodies in man that neutralized H3N2 influenza viruses were classified into three groups with distinct strain specificity: 1968-1973, 1977-1993 and 1997-2003
-
Okada J, et al. Monoclonal antibodies in man that neutralized H3N2 influenza viruses were classified into three groups with distinct strain specificity: 1968-1973, 1977-1993 and 1997-2003. Virology 2010;397:322-330.
-
(2010)
Virology
, vol.397
, pp. 322-330
-
-
Okada, J.1
-
195
-
-
79251501002
-
Localization of epitopes recognized by monoclonal antibodies that neutralized the H3N2 influenza viruses in man
-
Okada J, et al. Localization of epitopes recognized by monoclonal antibodies that neutralized the H3N2 influenza viruses in man. J Gen Virol 2011;92:326-335.
-
(2011)
J Gen Virol
, vol.92
, pp. 326-335
-
-
Okada, J.1
-
196
-
-
80055111172
-
Naturally occurring antibodies in humans can neutralize a variety of influenza virus strains, including H3, H1, H2, and H5
-
Ohshima N, Iba Y, Kubota-Koketsu R, Asano Y, Okuno Y, Kurosawa Y. Naturally occurring antibodies in humans can neutralize a variety of influenza virus strains, including H3, H1, H2, and H5. J Virol 2011;85:11048-11057.
-
(2011)
J Virol
, vol.85
, pp. 11048-11057
-
-
Ohshima, N.1
Iba, Y.2
Kubota-Koketsu, R.3
Asano, Y.4
Okuno, Y.5
Kurosawa, Y.6
-
197
-
-
63449125762
-
Cross-protective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A viruses
-
Yoshida R, et al. Cross-protective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A viruses. PLoS Pathog 2009;5:e1000350.
-
(2009)
PLoS Pathog
, vol.5
-
-
Yoshida, R.1
-
198
-
-
4444221565
-
UCSF Chimera-a visualization system for exploratory research and analysis
-
Pettersen EF, et al. UCSF Chimera-a visualization system for exploratory research and analysis. J Comput Chem 2004;25:1605-1612.
-
(2004)
J Comput Chem
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
-
199
-
-
0023660979
-
Structure of myohemerythrin in the azidomet state at 1.7/1.3 Å resolution
-
Sheriff S, Hendrickson WA, Smith JL. Structure of myohemerythrin in the azidomet state at 1.7/1.3 Å resolution. J Mol Biol 1987;197:273-296.
-
(1987)
J Mol Biol
, vol.197
, pp. 273-296
-
-
Sheriff, S.1
Hendrickson, W.A.2
Smith, J.L.3
|