A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

Science

Volumn 333, Issue 6044, 2011, Pages 850-856

  Corti, Davide ^a,b   Voss, Jarrod ^c   Gamblin, Steven J ^c   Codoni, Giosiana ^a   Macagno, Annalisa ^a   Jarrossay, David ^a   Vachieri, Sebastien G ^c   Pinna, Debora ^a   Minola, Andrea ^a   Vanzetta, Fabrizia ^b   Silacci, Chiara ^a   Fernandez Rodriguez, Blanca M ^a   Agatic, Gloria ^b   Bianchi, Siro ^b   Giacchetto Sasselli, Isabella ^a   Calder, Lesley ^c   Sallusto, Federica ^a   Collins, Patrick ^c   Haire, Lesley F ^c   Temperton, Nigel ^d   Langedijk, Johannes P M ^e,g   Skehel, John J ^c   Lanzavecchia, Antonio ^a,f   more..

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

^b Humabs BioMed SA ^*  (Switzerland)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^d UNIVERSITY OF KENT   (United Kingdom)

^e Pepscan Systems   (Netherlands)

^f ETH ZURICH   (Switzerland)

^g CRUCELL HOLLAND BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VIRUS HEMAGGLUTININ; MONOCLONAL ANTIBODY F16; MONOCLONAL ANTIBODY F16V3; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY; BIOCHEMISTRY; CRYSTALLOGRAPHY; CYTOLOGY; DISEASE TREATMENT; INFLUENZA; NEUTRALIZATION; PLASMA; PROTEIN; VIRUS; X-RAY SPECTROSCOPY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY ISOLATION; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG DESIGN; FERRET; INFLUENZA A; INFLUENZA VIRUS A; MOUSE; NONHUMAN; PASSIVE IMMUNIZATION; PLASMA CELL; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; ANTIGENS, VIRAL; CELLS, CULTURED; CROSS REACTIONS; CRYSTALLOGRAPHY, X-RAY; EPITOPES; FERRETS; GLYCOSYLATION; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN VARIABLE REGION; INFLUENZA A VIRUS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA B VIRUS; INFLUENZA, HUMAN; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; ORTHOMYXOVIRIDAE INFECTIONS; PLASMA CELLS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY;

INFLUENZA A VIRUS; MUS; MUSTELA;

EID: 80051670323     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1205669     Document Type: Article

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