Short constrained peptides that inhibit HIV-1 entry

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 23, 2002, Pages 14664-14669

  Sia, Samuel K ^a,b,e   Carr, Peter A ^a   Cochran, Andrea G ^c   Malashkevich, Vladimir N ^a   Kim, Peter S ^a,d  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HARVARD UNIVERSITY   (United States)

^c GENENTECH INC   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; GLYCOPROTEIN GP 41; SYNTHETIC PEPTIDE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CALORIMETRY; CELL FUSION; CIRCULAR DICHROISM; ENERGY TRANSFER; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN STABILITY; PROTEIN STRUCTURE; THERMODYNAMICS; VIRUS INHIBITION;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CALORIMETRY; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; ENTROPY; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; HYDROGEN BONDING; OLIGOPEPTIDES; THERMODYNAMICS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037069386     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.232566599     Document Type: Article

References (39)

1. Wild, C. T., Shugars, D. C., Greenwell, T. K., McDanal, C. B. & Matthews, T. J. (1994) Proc. Natl. Acad. Sci. USA 91, 9770-9774.
2. Chan, D. C., Chutkowski, C. T. & Kim, P. S. (1998) Proc. Natl. Acad. Sci. USA 95, 15613-15617.
3. Kilby, J. M., Hopkins, S., Venetta, T. M., DiMassimo, B., Cloud, G. A., Lee, J. Y., Alldredge, L., Hunter, E., Lambert, D., Bolognesi, D., et al. (1998) Nat. Med. 4, 1302-1307.
4. Chan, D. C., Fass, D., Berger, J. M. & Kim, P. S. (1997) Cell 89, 263-273.
5. Furuta, R. A., Wild, C. T., Weng, Y. & Weiss, C. D. (1998) Nat. Struct. Biol. 5, 276-279.
6. Weissenhorn, W., Dessen, A., Harrison, S. C., Skehel, J. J. & Wiley, D. C. (1997) Nature 387, 426-430.
7. Tan, K., Liu, J., Wang, J., Shen, S. & Lu, M. (1997) Proc. Natl. Acad. Sci. USA 94, 12303-12308.
8. Eckert, D. M. & Kim, P. S. (2001) Annu. Rev. Biochem. 70, 777-810.
9. Lu, M., Blacklow, S. C. & Kim, P. S. (1995) Nat. Struct. Biol. 2, 1075-1082.
10. Andrews, M. J. I. & Tabor, A. B. (1999) Tetrahedron 55, 11711-11743.
11. D'Aquino, J. A., Gomez, J., Hilser, V. J., Lee, K. H., Amzel, L. M. & Freire, E. (1996) Proteins 25, 143-156.
12. Jin, B. S., Ryu, J. R., Ahn, K. & Yu, Y. G. (2000) AIDS Res. Hum. Retroviruses 16, 1797-1804.
13. Judice, J. K., Tom, J. Y. K., Huang, W., Wrin, T., Vennari, J., Petropoulos, C. J. & McDowell, R. S. (1997) Proc. Natl. Acad. Sci. USA 94, 13426-13430.
14. DeGrado, W. F., Summa, C. M., Pavone, V., Nastri, F. & Lombardi, A. (1999) Annu. Rev. Biochem. 68, 779-819.
15. Karle, I. L. & Balaram, P. (1990) Biochemistry 29, 6747-6756.
16. O'Neill, K. T. & DeGrado, W. F. (1990) Science 250, 646-651.
17. Phelan, J. C., Skelton, N. J., Briasted, A. C. & McDowell, R. S. (1997) J. Am. Chem. Soc. 119, 455-460.
18. Cochran, A. G. (2001) Curr. Opin. Chem. Biol. 5, 654-659.
19. Eckert, D. M., Malashkevich, V. N., Hong, L. H., Carr, P. A. & Kim, P. S. (1999) Cell 99, 103-115.
20. Ferrer, M., Kapoor, T. M., Strassmaier, T., Weissenhorn, W., Skehel, J. J., Oprian, D., Schreiber, S. L., Wiley, D. C. & Harrison, S. C. (1999) Nat. Struct. Biol. 6, 953-960.
21. Skelton, N. J., Chen, Y. M., Dubree, N., Quan, C., Jackson, D. Y., Cochran, A., Zobel, K., Deshayes, K., Baca, M., Pisabarro, M. T. & Lowman, H. B. (2001) Biochemistry 40, 8487-8498.
22. Edelhoch, H. (1967) Biochemistry 6, 1948-1954.
23. Otwinowski, Z. (1993) Oscillation Data Reduction Program (Science and Engineering Research Council, Daresbury Laboratory, Warrington, U.K.).
24. Navaza, J. (2001) Acta Crystallogr. D 57, 1367-1372.
25. Jones, T. A., Zou, J. W., Cowan, S. & Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119.
26. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., et al. (1998) Acta Crystallogr. D 54, 905-921.
27. Yeates, T. O. (1997) Methods Enzymol. 276, 344-358.
28. Laskowski, R. A., MacArthur, M. W., Moss, D. S. & Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291.
29. Yang, J. T., Wu, C. C. & Martinez, H. M. (1986) Methods Enzymol. 130, 208-269.
30. Jasanoff, A. & Fersht, A. R. (1994) Biochemistry 33, 2129-2135.
31. Cole, J. L. & Garsky, V. M. (2001) Biochemistry 40, 5633-5641.
32. Kapurniotu, A. & Taylor, J. W. (1995) J. Med. Chem. 38, 836-847.
33. Cavanagh, J. & Akke, M. (2000) Nat. Struct. Biol. 7, 11-13.
34. Dunitz, J. D. (1995) Chem. Biol. 2, 709-712.
35. Vaughan, C. K., Buckle, A. M. & Fersht, A. R. (1999) J. Mol. Biol. 286, 1487-1506.
36. Zutshi, R., Brickner, M. & Chmielewski, J. (1998) Curr. Opin. Chem. Biol. 2, 62-66.
37. Peczuh, M. W. & Hamilton, A. D. (2000) Chem. Rev. 100, 2479-2494.
38. Cochran, A. G. (2000) Chem. Biol. 7, R85-R94.
39. Nicholls, A., Sharp, K. A. & Honig, B. (1991) Proteins 11, 281-296.