Structure-guided alterations of the gp41-directed HIV-1 broadly neutralizing antibody 2F5 reveal new properties regarding its neutralizing function

PLoS Pathogens

Volumn 8, Issue 7, 2012, Pages 28-

  Guenaga, Javier ^a   Wyatt, Richard T ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 GLYCOPROTEIN 1; CARDIOLIPIN; EPITOPE; HUMAN IMMUNODEFICIENCY VIRUS 1 ANTIBODY 2F5; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; VIRUS ANTIBODY; 2F5 MONOCLONAL ANTIBODY; 4E10 MONOCLONAL ANTIBODY; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; PLASTICITY; PROTEIN BINDING; PROTEIN INTERACTION; CELL LINE; CELL STRAIN HEK293; CHEMISTRY; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; PROTEIN TERTIARY STRUCTURE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; BETA 2-GLYCOPROTEIN I; CARDIOLIPINS; CELL LINE; EPITOPES; HEK293 CELLS; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84864621158     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002806     Document Type: Article

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