Guards and culprits in the endoplasmic reticulum: Glucolipotoxicity and β-cell failure in type II diabetes

Experimental Diabetes Research

Volumn 2012, Issue , 2012, Pages

  Karunakaran, Udayakumar ^a   Kim, Han Jong ^a   Kim, Joon Young ^a   Lee, In Kyu ^a  

^a School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CALCINEURIN; CALRETICULIN; CYTOCHROME C; FLAVONOID; GENISTEIN; GLUCAGON; GLUCOSE REGULATED PROTEIN 78; INSULIN; PALMITIC ACID; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN BCL 2; PROTEIN MCL 1; QUERCETIN; SALUBRINAL; TRANSACTIVATOR PROTEIN; TUMOR PROTEIN; X BOX BINDING PROTEIN 1; ANTIDIABETIC AGENT;

ABLATION THERAPY; APOPTOSIS; CALCIUM DEPLETION; CELL DEATH; CYTOSOL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; HUMAN; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN SYNTHESIS; LIPOTOXICITY; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PANCREAS ISLET BETA CELL; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN SYNTHESIS; REVIEW; ANIMAL; DRUG EFFECT; GLUCOSE BLOOD LEVEL; LIPID METABOLISM; METABOLISM; PATHOLOGY; PHYSIOLOGICAL STRESS; UNFOLDED PROTEIN RESPONSE;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN-SECRETING CELLS; LIPID METABOLISM; MITOCHONDRIA; STRESS, PHYSIOLOGICAL; UNFOLDED PROTEIN RESPONSE;

EID: 84855165061     PISSN: 16875214     EISSN: 16875303     Source Type: Journal    
DOI: 10.1155/2012/639762     Document Type: Review

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