Genistein induces pancreatic β-cell proliferation through activation of multiple signaling pathways and prevents insulin-deficient diabetes in mice

Endocrinology

Volumn 151, Issue 7, 2010, Pages 3026-3037

  Fu, Zhuo ^a   Zhang, Wen ^a   Zhen, Wei ^a   Lum, Hazel ^d   Nadler, Jerry ^e   Bassaganya Riera, Josep ^b   Jia, Zhenquan ^c   Wang, Yanwen ^f   Misra, Hara ^c   Liu, Dongmin ^a  

^a Fralin Translational Obesity Research Center   (United States)

^b VIRGINIA BIOINFORMATICS INSTITUTE   (United States)

^c EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^d RUSH UNIVERSITY MEDICAL CENTER   (United States)

^e EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^f NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHANIN A; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN D1; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; EQUOL; ESTROGEN RECEPTOR; FLAVONOID; FORMONONETIN; GENISTEIN; GENISTIN; GLUCOSE; GLYCEITIN; INSULIN; KAEMPFEROL; LIPID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; QUERCETIN; RESVERATROL; UNCLASSIFIED DRUG; ANTIOXIDANT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN DEFICIENCY; LIPID BLOOD LEVEL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; ANIMAL; BLOOD; C57BL MOUSE; CELL LINE; CYTOLOGY; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIVER; MALE; METABOLISM;

ANIMALS; ANTIOXIDANTS; CELL LINE; CELL PROLIFERATION; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIABETES MELLITUS; DIABETES MELLITUS, EXPERIMENTAL; GENISTEIN; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN-SECRETING CELLS; LIVER; MALE; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; SIGNAL TRANSDUCTION;

EID: 77954580620     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-1294     Document Type: Article

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