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Volumn 95, Issue 3, 2010, Pages 1442-1449

Enhanced signaling downstream of ribonucleic acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CCAAT ENHANCER BINDING PROTEIN; INITIATION FACTOR 2ALPHA; INOSITOL; OLEIC ACID; PALMITIC ACID;

EID: 77749246118     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2009-2322     Document Type: Article
Times cited : (50)

References (40)
  • 1
    • 0035125001 scopus 로고    scopus 로고
    • β-Cell dysfunction and failure in type 2 diabetes: Potential mechanisms
    • Porte Jr D, Kahn SE 2001 β-Cell dysfunction and failure in type 2 diabetes: potential mechanisms. Diabetes 50(Suppl 1):S160-S163
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 1
    • Porte Jr, D.1    Kahn, S.E.2
  • 3
    • 0037036968 scopus 로고    scopus 로고
    • Diet and risk of coronary heart disease and type 2 diabetes
    • Mann JI 2002 Diet and risk of coronary heart disease and type 2 diabetes. Lancet 360:783-789
    • (2002) Lancet , vol.360 , pp. 783-789
    • Mann, J.I.1
  • 4
    • 33644749322 scopus 로고    scopus 로고
    • Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: Many differences, few similarities
    • Cnop M, Welsh N, Jonas JC, Jorns A, Lenzen S, Eizirik DL 2005 Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 54(Suppl 2):S97-S107
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 2
    • Cnop, M.1    Welsh, N.2    Jonas, J.C.3    Jorns, A.4    Lenzen, S.5    Eizirik, D.L.6
  • 5
    • 9244231766 scopus 로고    scopus 로고
    • Free fatty acids and cytokines induce pancreatic β-cell apoptosis by different mechanisms: Role of nuclear factor-κB and endoplasmic reticulum stress
    • Kharroubi I, Ladrière L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL 2004 Free fatty acids and cytokines induce pancreatic β-cell apoptosis by different mechanisms: role of nuclear factor-κB and endoplasmic reticulum stress. Endocrinology 145:5087-5096
    • (2004) Endocrinology , vol.145 , pp. 5087-5096
    • Kharroubi, I.1    Ladrière, L.2    Cardozo, A.K.3    Dogusan, Z.4    Cnop, M.5    Eizirik, D.L.6
  • 6
    • 39149104320 scopus 로고    scopus 로고
    • The role for endoplasmic reticulum stress in diabetes mellitus
    • Eizirik DL, Cardozo AK, Cnop M 2008 The role for endoplasmic reticulum stress in diabetes mellitus. Endocr Rev 29:42-61
    • (2008) Endocr Rev , vol.29 , pp. 42-61
    • Eizirik, D.L.1    Cardozo, A.K.2    Cnop, M.3
  • 8
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D, Walter P 2007 Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8:519-529
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 10
    • 33646171699 scopus 로고    scopus 로고
    • Divergent roles of IRE1α and PERK in the unfolded protein response
    • Schröder M, Kaufman RJ 2006 Divergent roles of IRE1α and PERK in the unfolded protein response. Curr Mol Med 6:5-36
    • (2006) Curr Mol Med , vol.6 , pp. 5-36
    • Schröder, M.1    Kaufman, R.J.2
  • 11
    • 33645154135 scopus 로고    scopus 로고
    • Cellular response to endoplasmic reticulum stress: A matter of life or death
    • Boyce M, Yuan J 2006 Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 13:363-373
    • (2006) Cell Death Differ , vol.13 , pp. 363-373
    • Boyce, M.1    Yuan, J.2
  • 17
    • 0034425698 scopus 로고    scopus 로고
    • EIF2AK3, encoding translation initiation factor 2-α kinase 3, is mutated in patients with Wolcott-Rallison syndrome
    • Delépine M, Nicolino M, Barrett T, Golamaully M, Lathrop GM, Julier C 2000 EIF2AK3, encoding translation initiation factor 2-α kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat Genet 25:406-409
    • (2000) Nat Genet , vol.25 , pp. 406-409
    • Delépine, M.1    Nicolino, M.2    Barrett, T.3    Golamaully, M.4    Lathrop, G.M.5    Julier, C.6
  • 20
    • 34547638958 scopus 로고    scopus 로고
    • High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated β-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes
    • Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA, Butler PC 2007 High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated β-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes. Diabetes 56:2016-2027
    • (2007) Diabetes , vol.56 , pp. 2016-2027
    • Huang, C.J.1    Lin, C.Y.2    Haataja, L.3    Gurlo, T.4    Butler, A.E.5    Rizza, R.A.6    Butler, P.C.7
  • 24
    • 33947510911 scopus 로고    scopus 로고
    • Selective inhibition of eukaryotic translation initiation factor 2α dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic β-cell dysfunction and apoptosis
    • Cnop M, Ladriere L, Hekerman P, Ortis F, Cardozo AK, Dogusan Z, Flamez D, Boyce M, Yuan J, Eizirik DL 2007 Selective inhibition of eukaryotic translation initiation factor 2α dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic β-cell dysfunction and apoptosis. J Biol Chem 282:3989-3997
    • (2007) J Biol Chem , vol.282 , pp. 3989-3997
    • Cnop, M.1    Ladriere, L.2    Hekerman, P.3    Ortis, F.4    Cardozo, A.K.5    Dogusan, Z.6    Flamez, D.7    Boyce, M.8    Yuan, J.9    Eizirik, D.L.10
  • 26
    • 73249116246 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 agonists protect pancreatic β-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB
    • Cunha DA, Ladrière L, Ortis F, Igoillo-Esteve M, Gurzov EN, Lupi R, Marchetti P, Eizirik DL, Cnop M 2009 Glucagon-like peptide-1 agonists protect pancreatic β-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB. Diabetes 58: 2851-2862
    • (2009) Diabetes , vol.58 , pp. 2851-2862
    • Cunha, D.A.1    Ladrière, L.2    Ortis, F.3    Igoillo-Esteve, M.4    Gurzov, E.N.5    Lupi, R.6    Marchetti, P.7    Eizirik, D.L.8    Cnop, M.9
  • 28
    • 0035430782 scopus 로고    scopus 로고
    • Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation
    • Cnop M, Hannaert JC, Hoorens A, Eizirik DL, Pipeleers DG 2001 Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation. Diabetes 50:1771-1777
    • (2001) Diabetes , vol.50 , pp. 1771-1777
    • Cnop, M.1    Hannaert, J.C.2    Hoorens, A.3    Eizirik, D.L.4    Pipeleers, D.G.5
  • 31
    • 0026550830 scopus 로고
    • Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines
    • Asfari M, Janjic D, Meda P, Li G, Halban PA, Wollheim CB 1992 Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 130:167-178
    • (1992) Endocrinology , vol.130 , pp. 167-178
    • Asfari, M.1    Janjic, D.2    Meda, P.3    Li, G.4    Halban, P.A.5    Wollheim, C.B.6
  • 32
    • 0035079807 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 β-exposed human and rat islet cells
    • Chen MC, Proost P, Gysemans C, Mathieu C, Eizirik DL 2001 Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 β-exposed human and rat islet cells. Diabetologia 44:325-332
    • (2001) Diabetologia , vol.44 , pp. 325-332
    • Chen, M.C.1    Proost, P.2    Gysemans, C.3    Mathieu, C.4    Eizirik, D.L.5
  • 33
    • 15944369290 scopus 로고    scopus 로고
    • ER stress signaling by regulated splicing: IRE1/HAC1/XBP1
    • Back SH, Schröder M, Lee K, Zhang K, Kaufman RJ 2005 ER stress signaling by regulated splicing: IRE1/HAC1/XBP1. Methods 35: 395-416
    • (2005) Methods , vol.35 , pp. 395-416
    • Back, S.H.1    Schröder, M.2    Lee, K.3    Zhang, K.4    Kaufman, R.J.5
  • 36
    • 34047235220 scopus 로고    scopus 로고
    • Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells
    • Pirot P, Ortis F, Cnop M, Ma Y, Hendershot LM, Eizirik DL, Cardozo AK 2007 Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells. Diabetes 56:1069-1077
    • (2007) Diabetes , vol.56 , pp. 1069-1077
    • Pirot, P.1    Ortis, F.2    Cnop, M.3    Ma, Y.4    Hendershot, L.M.5    Eizirik, D.L.6    Cardozo, A.K.7
  • 38
    • 39449091637 scopus 로고    scopus 로고
    • A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death
    • Boyce M, Py BF, Ryazanov AG, Minden JS, Long K, Ma D, Yuan J 2008 A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death. Cell Death Differ 15:589-599
    • (2008) Cell Death Differ , vol.15 , pp. 589-599
    • Boyce, M.1    Py, B.F.2    Ryazanov, A.G.3    Minden, J.S.4    Long, K.5    Ma, D.6    Yuan, J.7
  • 39
    • 33745736330 scopus 로고    scopus 로고
    • Mitochondrial membrane dynamics, cristae remodelling and apoptosis
    • Heath-Engel HM, Shore GC 2006 Mitochondrial membrane dynamics, cristae remodelling and apoptosis. Biochim Biophys Acta 1763:549-560
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 549-560
    • Heath-Engel, H.M.1    Shore, G.C.2
  • 40
    • 50949127216 scopus 로고    scopus 로고
    • Correlated light and electron microscopy illuminates the role of mitochondrial inner membrane remodeling during apoptosis
    • Frey TG, Sun MG 2008 Correlated light and electron microscopy illuminates the role of mitochondrial inner membrane remodeling during apoptosis. Biochim Biophys Acta 1777:847-852
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 847-852
    • Frey, T.G.1    Sun, M.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.