메뉴 건너뛰기




Volumn 19, Issue 8, 1999, Pages 5659-5674

Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH2-terminal kinase activity, and apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CASPASE 3; CYTOCHROME C; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN BCL 2; PROTEIN BCL X; STRESS ACTIVATED PROTEIN KINASE; THAPSIGARGIN;

EID: 0032802315     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.8.5659     Document Type: Article
Times cited : (152)

References (73)
  • 1
    • 0027231742 scopus 로고
    • Nitric oxide-mediated apoptosis in murine peritonial macrophages
    • Albina, J. E., S. Cui, R. B. Mateo, and J. S. Reichner. 1993. Nitric oxide-mediated apoptosis in murine peritonial macrophages. J. Immunol. 150: 5080-5085.
    • (1993) J. Immunol. , vol.150 , pp. 5080-5085
    • Albina, J.E.1    Cui, S.2    Mateo, R.B.3    Reichner, J.S.4
  • 2
    • 0027523461 scopus 로고
    • Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production
    • Baffy, G., T. Miyashita, J. R. Williamson, and J. C. Reed. 1993. Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production. J. Biol. Chem. 268:6511-6519.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6511-6519
    • Baffy, G.1    Miyashita, T.2    Williamson, J.R.3    Reed, J.C.4
  • 3
    • 0025241953 scopus 로고
    • Phosphatidylinositol-derived precursors and signals
    • Bansal, V. S., and P. W. Majerus. 1990. Phosphatidylinositol-derived precursors and signals. Annu. Rev. Cell Biol. 6:41-67.
    • (1990) Annu. Rev. Cell Biol. , vol.6 , pp. 41-67
    • Bansal, V.S.1    Majerus, P.W.2
  • 4
    • 0028053663 scopus 로고
    • Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane
    • Bernardi, P., K. M. Broekemeier, and D. R. Pfeiffer. 1994. Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane. J. Bioenerg. Biomembr. 26:509-517.
    • (1994) J. Bioenerg. Biomembr. , vol.26 , pp. 509-517
    • Bernardi, P.1    Broekemeier, K.M.2    Pfeiffer, D.R.3
  • 6
    • 0030041536 scopus 로고    scopus 로고
    • Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in radiation-induced apoptosis
    • Chen, Y.-R., C. F. Meyer, and T.-H. Tan. 1996. Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in radiation-induced apoptosis. J. Biol. Chem. 271:631-634.
    • (1996) J. Biol. Chem. , vol.271 , pp. 631-634
    • Chen, Y.-R.1    Meyer, C.F.2    Tan, T.-H.3
  • 7
    • 0029753773 scopus 로고    scopus 로고
    • The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and radiation
    • Chen, Y.-R., X. Wang, D. Templeton, R. Davis, and T.-H. Tan. 1996. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and radiation. J. Biol. Chem. 271:31929-31936.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31929-31936
    • Chen, Y.-R.1    Wang, X.2    Templeton, D.3    Davis, R.4    Tan, T.-H.5
  • 9
    • 0032100446 scopus 로고    scopus 로고
    • Caspase activation is required for nitric oxide-mediated, CD95(APO-1/Fas)-dependent and independent apoptosis in human neoplastic lymphoid cells
    • Chlichlia K, M. E. Peter, M. Rocha, C. Scaffidi, M. Bucur, P. H. Krammer, V. Schirrmacher, and V. Umansky. 1998. Caspase activation is required for nitric oxide-mediated, CD95(APO-1/Fas)-dependent and independent apoptosis in human neoplastic lymphoid cells. Blood 91:4311-4320.
    • (1998) Blood , vol.91 , pp. 4311-4320
    • Chlichlia, K.1    Peter, M.E.2    Rocha, M.3    Scaffidi, C.4    Bucur, M.5    Krammer, P.H.6    Schirrmacher, V.7    Umansky, V.8
  • 10
    • 0027279667 scopus 로고
    • Identification of a transitional preapoptotic population of thymocytes
    • Cohen, G. M., X.-M. Sun, R. T. Snowden, M. G. Ormerod, and D. Dinsdale. 1993. Identification of a transitional preapoptotic population of thymocytes. J. Immunol. 151:566-574.
    • (1993) J. Immunol. , vol.151 , pp. 566-574
    • Cohen, G.M.1    Sun, X.-M.2    Snowden, R.T.3    Ormerod, M.G.4    Dinsdale, D.5
  • 11
    • 0028935974 scopus 로고
    • Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
    • Dérijard, B., J. Raingeaud, T. Barrett, I.-H. Wu, J. Han, R. Ulevitch, and R. Davis. 1995. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267:682-685.
    • (1995) Science , vol.267 , pp. 682-685
    • Dérijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.-H.4    Han, J.5    Ulevitch, R.6    Davis, R.7
  • 12
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Dérijard, B., M. Hibi, I.-H. Wu, T. Barret, B. Su, T. Deng, M. Karin, and R. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Dérijard, B.1    Hibi, M.2    Wu, I.-H.3    Barret, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.8
  • 13
    • 0019835356 scopus 로고
    • Mitochondria: A historical review
    • Ernster, L., and G. Schatz. 1981. Mitochondria: a historical review. J. Cell Biol. 91:227-255.
    • (1981) J. Cell Biol. , vol.91 , pp. 227-255
    • Ernster, L.1    Schatz, G.2
  • 15
    • 0030039911 scopus 로고    scopus 로고
    • Apoptotic death of human leukemic cells induced by vascular cells expressing nitric oxide synthase in response to γ-interferon and tumor necrosis factor-α
    • Geng, Y.-J., K. Hellstrand, A. Wennmalm, and G. K. Hansson. 1996. Apoptotic death of human leukemic cells induced by vascular cells expressing nitric oxide synthase in response to γ-interferon and tumor necrosis factor-α. Cancer Res. 56:866-871.
    • (1996) Cancer Res. , vol.56 , pp. 866-871
    • Geng, Y.-J.1    Hellstrand, K.2    Wennmalm, A.3    Hansson, G.K.4
  • 16
    • 0032079478 scopus 로고    scopus 로고
    • Production of nitric oxide by mitochondria
    • Giulivi, C., J. J. Poderosa, and A. Boveris. 1998. Production of nitric oxide by mitochondria. J. Biol. Chem. 273:11038-11043.
    • (1998) J. Biol. Chem. , vol.273 , pp. 11038-11043
    • Giulivi, C.1    Poderosa, J.J.2    Boveris, A.3
  • 17
    • 0030697859 scopus 로고    scopus 로고
    • Nitric oxide synthase activity in mitochondria
    • Ghafourifar, P., and C. Richter. 1997. Nitric oxide synthase activity in mitochondria. FEBS Lett. 418:291-296.
    • (1997) FEBS Lett. , vol.418 , pp. 291-296
    • Ghafourifar, P.1    Richter, C.2
  • 18
    • 0029012476 scopus 로고
    • A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
    • Ham, J., C. Babij, J. Whitfield, C. Pfarr, D. Lallemand, M. Yaniv, and L. Rubin. 1995. A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14:927-939.
    • (1995) Neuron , vol.14 , pp. 927-939
    • Ham, J.1    Babij, C.2    Whitfield, J.3    Pfarr, C.4    Lallemand, D.5    Yaniv, M.6    Rubin, L.7
  • 19
    • 0030824575 scopus 로고    scopus 로고
    • Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2
    • He, H., M. Lam, T. S. McCormic, and C. W. Distelhorst. 1997. Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2. J. Cell Biol. 138:1219-1228.
    • (1997) J. Cell Biol. , vol.138 , pp. 1219-1228
    • He, H.1    Lam, M.2    McCormic, T.S.3    Distelhorst, C.W.4
  • 21
    • 0024407432 scopus 로고
    • Characterization of Jun D: A new member of the jun proto-oncogene family
    • Hirai, S., R. Ryseck, F. Mechta, R. Bravo, and M. Yaniv. 1989. Characterization of Jun D: a new member of the jun proto-oncogene family. EMBO J. 8:1433-1439.
    • (1989) EMBO J. , vol.8 , pp. 1433-1439
    • Hirai, S.1    Ryseck, R.2    Mechta, F.3    Bravo, R.4    Yaniv, M.5
  • 22
    • 0028796225 scopus 로고
    • Defining apoptosis
    • Hockenbery, D. 1995. Defining apoptosis. Am. J. Pathol. 146:16-19.
    • (1995) Am. J. Pathol. , vol.146 , pp. 16-19
    • Hockenbery, D.1
  • 23
    • 0027485461 scopus 로고
    • Bcl-2 functions in an antioxidant pathway to prevent apoptosis
    • Hockenbery, D., Z. Oltvai, X.-M. Yin, C. Milliman, and S. Korsmeyer. 1993. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251.
    • (1993) Cell , vol.75 , pp. 241-251
    • Hockenbery, D.1    Oltvai, Z.2    Yin, X.-M.3    Milliman, C.4    Korsmeyer, S.5
  • 24
    • 0031587822 scopus 로고    scopus 로고
    • Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals
    • Ichas, F., L. S. Jouaville, and J.-P. Mazat. 1997. Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals. Cell 89:1145-1153.
    • (1997) Cell , vol.89 , pp. 1145-1153
    • Ichas, F.1    Jouaville, L.S.2    Mazat, J.-P.3
  • 28
    • 0030843575 scopus 로고    scopus 로고
    • L inhibits ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis
    • L inhibits ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis. Cancer Res. 57:3115-3120.
    • (1997) Cancer Res. , vol.57 , pp. 3115-3120
    • Kim, C.N.1    Wang, H.2    Huang, Y.3    Ibrado, A.M.4    Liu, L.5    Fang, G.6    Bhalla, K.7
  • 29
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck, R. M., E. Bossy-Wetzel, D. R. Green, and D. D. Newmeyer. 1997. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275:1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 34
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu, X., C. N. Kim, J. Yang, R. Jemmerson, and X. Wang. 1996. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 35
    • 0028924419 scopus 로고
    • Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress
    • Liu, Y., M. Gorospe, C. Yang, and N. J. Holbrook. 1995. Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. J. Biol. Chem. 270:8377-8380.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8377-8380
    • Liu, Y.1    Gorospe, M.2    Yang, C.3    Holbrook, N.J.4
  • 36
    • 0032488992 scopus 로고    scopus 로고
    • Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway
    • Luo, Y., H. Umegaki, X. Wang, R. Abe, and G. S. Roth. 1998. Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway. J. Biol. Chem. 273:3756-3764.
    • (1998) J. Biol. Chem. , vol.273 , pp. 3756-3764
    • Luo, Y.1    Umegaki, H.2    Wang, X.3    Abe, R.4    Roth, G.S.5
  • 37
    • 0028171826 scopus 로고
    • Bcl-2 overexpression abolishes early calcium waving preceding apoptosis in NIH-3T3 murine fibroblasts
    • Magnelli, L., M. Cinelli, A. Turchetti, and V. P. Chiarugi. 1994. Bcl-2 overexpression abolishes early calcium waving preceding apoptosis in NIH-3T3 murine fibroblasts. Biochem. Biophys. Res. Commun. 204:84-90.
    • (1994) Biochem. Biophys. Res. Commun. , vol.204 , pp. 84-90
    • Magnelli, L.1    Cinelli, M.2    Turchetti, A.3    Chiarugi, V.P.4
  • 39
    • 0029826376 scopus 로고    scopus 로고
    • Dopamine induces apoptotic cell death of a catecholaminergic cell line derived from the central nervous system
    • Masserano, J. M., L. Gong, H. Kulaga, I. Baker, and R. J. Wyatt. 1996. Dopamine induces apoptotic cell death of a catecholaminergic cell line derived from the central nervous system. Mol. Pharmacol. 50:1309-1315.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1309-1315
    • Masserano, J.M.1    Gong, L.2    Kulaga, H.3    Baker, I.4    Wyatt, R.J.5
  • 42
    • 0029845983 scopus 로고    scopus 로고
    • Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria
    • USA
    • Murphy, A. N., D. E. Bredesen, G. Cortopassi, E. Wang, and G. Fiskum. 1996. Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proc. Natl. Acad. Sci. (USA) 93:9893-9898.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 9893-9898
    • Murphy, A.N.1    Bredesen, D.E.2    Cortopassi, G.3    Wang, E.4    Fiskum, G.5
  • 43
    • 0028092958 scopus 로고
    • Nitric oxide synthase: Rolles, tolls, and controls
    • Nathan, C. F., and Q.-W. Xie. 1994. Nitric oxide synthase: rolles, tolls, and controls. Cell 78:915-922.
    • (1994) Cell , vol.78 , pp. 915-922
    • Nathan, C.F.1    Xie, Q.-W.2
  • 44
    • 0028923778 scopus 로고
    • Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide
    • Nieminen, A. L., A. K. Saylor, S. A. Tesfai, B. Herman, and J. J. Lemasters. 1995. Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. Biochem. J. 307:99-106.
    • (1995) Biochem. J. , vol.307 , pp. 99-106
    • Nieminen, A.L.1    Saylor, A.K.2    Tesfai, S.A.3    Herman, B.4    Lemasters, J.J.5
  • 45
    • 0028149786 scopus 로고
    • Checkpoints of dueling dimers foil death wishes
    • Oltvai, Z. N., and S. J. Korsmeyer. 1994. Checkpoints of dueling dimers foil death wishes. Cell 79:189-192.
    • (1994) Cell , vol.79 , pp. 189-192
    • Oltvai, Z.N.1    Korsmeyer, S.J.2
  • 47
    • 0033605366 scopus 로고    scopus 로고
    • Activation of stress-activated protein kinase/c-Jun NH2-terminal kinase and p38 kinase in calphostin C-induced apoptosis requires caspase-3-like proteases but is dispensable for cell death
    • Ozaki, I., E. Tani, H. Ikemoto, H. Kitagawa, and H. Fujikawa. 1999. Activation of stress-activated protein kinase/c-Jun NH2-terminal kinase and p38 kinase in calphostin C-induced apoptosis requires caspase-3-like proteases but is dispensable for cell death. J. Biol. Chem. 274:5310-5317.
    • (1999) J. Biol. Chem. , vol.274 , pp. 5310-5317
    • Ozaki, I.1    Tani, E.2    Ikemoto, H.3    Kitagawa, H.4    Fujikawa, H.5
  • 49
    • 0032571294 scopus 로고    scopus 로고
    • The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition
    • Pastorino, J. G., S.-T. Chen, M. Tafani, J. W. Snyder, and J. F. Farber. 1998. The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J. Biol. Chem. 273:7770-7775.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7770-7775
    • Pastorino, J.G.1    Chen, S.-T.2    Tafani, M.3    Snyder, J.W.4    Farber, J.F.5
  • 50
    • 0025242698 scopus 로고
    • Review of the current status of calcium and thiols in cellular injury
    • Reed, D. J. 1990. Review of the current status of calcium and thiols in cellular injury. Chem. Res. Toxicol. 3:495-502.
    • (1990) Chem. Res. Toxicol. , vol.3 , pp. 495-502
    • Reed, D.J.1
  • 51
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the Bcl-2 family
    • Reed, J. C. 1997. Double identity for proteins of the Bcl-2 family. Nature 387:773-776.
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 52
    • 0030782177 scopus 로고    scopus 로고
    • Cytochrome c: Can't live with it - Can't live without it
    • Reed, J. C. 1997. Cytochrome c: can't live with it - can't live without it. Cell 91:559-562.
    • (1997) Cell , vol.91 , pp. 559-562
    • Reed, J.C.1
  • 53
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed, J. C. 1994. Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124:1-6.
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 54
    • 0022472020 scopus 로고
    • Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of Indo-1 and immunofluorescence with flow cytometry
    • Rabinovitch, P. S., C. H. June, A. Grossman, and J. A. Ledbetter. 1986. Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of Indo-1 and immunofluorescence with flow cytometry. J. Immunol. 137:952-961.
    • (1986) J. Immunol. , vol.137 , pp. 952-961
    • Rabinovitch, P.S.1    June, C.H.2    Grossman, A.3    Ledbetter, J.A.4
  • 55
    • 0027325097 scopus 로고
    • 2+: Their relationship to apoptosis and oncogenesis
    • 2+: their relationship to apoptosis and oncogenesis. FEBS Lett. 325:104-107.
    • (1993) FEBS Lett. , vol.325 , pp. 104-107
    • Richter, C.1
  • 57
    • 0025361036 scopus 로고
    • The involvement of calcium in transport of secretary proteins from the endoplasmic reticulum
    • Sambrook, J. F. 1990. The involvement of calcium in transport of secretary proteins from the endoplasmic reticulum. Cell 61:197-199.
    • (1990) Cell , vol.61 , pp. 197-199
    • Sambrook, J.F.1
  • 58
    • 0031813790 scopus 로고    scopus 로고
    • Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase
    • Srivastava, R. K., A. R. Srivastava, S. J. Korsmeyer, M. Nesterova, Y. S. Cho-Chung, and D. L. Longo. 1998. Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase. Mol. Cell. Biol. 18:3509-3517.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3509-3517
    • Srivastava, R.K.1    Srivastava, A.R.2    Korsmeyer, S.J.3    Nesterova, M.4    Cho-Chung, Y.S.5    Longo, D.L.6
  • 60
    • 0030785790 scopus 로고    scopus 로고
    • The central execution of apoptosis: Multiple connections between protease activation and mitochondria in Fas/ APO-1/CD95- and ceramide-induced apoptosis
    • Susin, S. A., N. Zamzami, M. Castedo, E. Daugas, H. G. Wang, S. Geley, F. Fassy, J. C. Reed, and G. Kroemer. 1997. The central execution of apoptosis: multiple connections between protease activation and mitochondria in Fas/ APO-1/CD95- and ceramide-induced apoptosis. J. Exp. Med. 186:25-37.
    • (1997) J. Exp. Med. , vol.186 , pp. 25-37
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3    Daugas, E.4    Wang, H.G.5    Geley, S.6    Fassy, F.7    Reed, J.C.8    Kroemer, G.9
  • 61
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C. B. 1995. Apoptosis in the pathogenesis and treatment of disease. Science 267:1456.
    • (1995) Science , vol.267 , pp. 1456
    • Thompson, C.B.1
  • 62
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry, N. A., and Y. Lazebnik. 1998. Caspases: enemies within. Science 281:1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 63
    • 0032955601 scopus 로고    scopus 로고
    • Caspase activation accompanying cytochrome c release from mitochondria is possibly involved in nitric oxide-induced neuronal apoptosis in SH-SY5Y cells
    • Uehara, T., Y. Kikuchi, and Y. Nomura. 1999. Caspase activation accompanying cytochrome c release from mitochondria is possibly involved in nitric oxide-induced neuronal apoptosis in SH-SY5Y cells. J. Neurochem. 72:196-205.
    • (1999) J. Neurochem. , vol.72 , pp. 196-205
    • Uehara, T.1    Kikuchi, Y.2    Nomura, Y.3
  • 64
    • 0033120803 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome C release
    • Ushmorov A., F. Ratter, V. Lehmann, W. Droge, V. Schirrmacher, and V. Umansky. 1999. Nitric oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome C release. Blood 93:2342-2352.
    • (1999) Blood , vol.93 , pp. 2342-2352
    • Ushmorov, A.1    Ratter, F.2    Lehmann, V.3    Droge, W.4    Schirrmacher, V.5    Umansky, V.6
  • 65
    • 0345585465 scopus 로고    scopus 로고
    • Activated endothelia cells induce apoptosis in lymphoma cells: Role of nitric oxide
    • Umansky, V., M. Bucur, V. Schirrmacher, and M. Rocha. 1997. Activated endothelia cells induce apoptosis in lymphoma cells: role of nitric oxide. Int. J. Oncol. 3:1043-1050.
    • (1997) Int. J. Oncol. , vol.3 , pp. 1043-1050
    • Umansky, V.1    Bucur, M.2    Schirrmacher, V.3    Rocha, M.4
  • 66
    • 0028046038 scopus 로고
    • Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40
    • Vavssiäre, J.-L, P. X. Petit, Y. Risler, and B. Mignotte. 1994. Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc. Natl. Acad. Sci. USA 91:11752-11756.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11752-11756
    • Vavssiäre, J.-L.1    Petit, P.X.2    Risler, Y.3    Mignotte, B.4
  • 68
    • 0031954631 scopus 로고    scopus 로고
    • MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis
    • Widmann C., P. Gerwins, N. L. Johnson, M. B. Jarpe, and G. L. Johnson. 1998. MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis. Mol. Cell. Biol. 18:2416-2429.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2416-2429
    • Widmann, C.1    Gerwins, P.2    Johnson, N.L.3    Jarpe, M.B.4    Johnson, G.L.5
  • 69
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia, Z., M. Dickens, J. Raingeaud, R. Davis, and M. Greenberg. 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.4    Greenberg, M.5
  • 72
    • 0024996681 scopus 로고
    • The oxidative inactivation of mitochondrial electron transport chain components and ATPase
    • Zhang, Y., O. Marcillat, C. Giulivi, L. Ernster, and K. J. A. Davies. 1990. The oxidative inactivation of mitochondrial electron transport chain components and ATPase. J. Biol. Chem. 265:16330-16336.
    • (1990) J. Biol. Chem. , vol.265 , pp. 16330-16336
    • Zhang, Y.1    Marcillat, O.2    Giulivi, C.3    Ernster, L.4    Davies, K.J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.