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Volumn 132, Issue 2, 2011, Pages 204-214

Sensing sterile injury: Opportunities for pharmacological control

Author keywords

Cell death; Cell signaling; Danger associated molecular patterns; Neutrophil recruitment; Pharmacological therapy; Sterile inflammation

Indexed keywords

ANTIINFLAMMATORY AGENT; CYTOKINE; DNA; IMMUNOMODULATING AGENT; NUCLEIC ACID; RNA;

EID: 80052315815     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2011.07.002     Document Type: Review
Times cited : (14)

References (177)
  • 1
    • 70349459734 scopus 로고    scopus 로고
    • RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
    • A. Ablasser, F. Bauernfeind, G. Hartmann, E. Latz, K.A. Fitzgerald, and V. Hornung RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate Nat Immunol 10 2009 1065 1072
    • (2009) Nat Immunol , vol.10 , pp. 1065-1072
    • Ablasser, A.1    Bauernfeind, F.2    Hartmann, G.3    Latz, E.4    Fitzgerald, K.A.5    Hornung, V.6
  • 2
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
    • DOI 10.1038/35099560
    • L. Alexopoulou, A.C. Holt, R. Medzhitov, and R.A. Flavell Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 Nature 413 2001 732 738 (Pubitemid 33009951)
    • (2001) Nature , vol.413 , Issue.6857 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 3
    • 64049111768 scopus 로고    scopus 로고
    • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
    • I.C. Allen, M.A. Scull, C.B. Moore, E.K. Holl, E. McElvania-TeKippe, and D.J. Taxman The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA Immunity 30 2009 556 565
    • (2009) Immunity , vol.30 , pp. 556-565
    • Allen, I.C.1    Scull, M.A.2    Moore, C.B.3    Holl, E.K.4    McElvania-Tekippe, E.5    Taxman, D.J.6
  • 4
    • 33644654915 scopus 로고    scopus 로고
    • Molecular mechanisms of alcoholic pancreatitis
    • DOI 10.1159/000090170
    • M.V. Apte, R.C. Pirola, and J.S. Wilson Molecular mechanisms of alcoholic pancreatitis Dig Dis 23 2005 232 240 (Pubitemid 43325922)
    • (2005) Digestive Diseases , vol.23 , Issue.3-4 , pp. 232-240
    • Apte, M.V.1    Pirola, R.C.2    Wilson, J.S.3
  • 5
    • 79958798010 scopus 로고    scopus 로고
    • A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases
    • N. Arulkumaran, R.J. Unwin, and F.W. Tam A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases Expert Opin Investig Drugs 20 7 2011 897 915
    • (2011) Expert Opin Investig Drugs , vol.20 , Issue.7 , pp. 897-915
    • Arulkumaran, N.1    Unwin, R.J.2    Tam, F.W.3
  • 7
    • 29244450802 scopus 로고    scopus 로고
    • Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
    • DOI 10.1038/ni1280, PII N1280
    • G.M. Barton, J.C. Kagan, and R. Medzhitov Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA Nat Immunol 7 2006 49 56 (Pubitemid 41823868)
    • (2006) Nature Immunology , vol.7 , Issue.1 , pp. 49-56
    • Barton, G.M.1    Kagan, J.C.2    Medzhitov, R.3
  • 8
    • 0347994956 scopus 로고    scopus 로고
    • Essential Role for Neutrophil Recruitment to the Liver in Concanavalin A-Induced Hepatitis
    • C.S. Bonder, M.N. Ajuebor, L.D. Zbytnuik, P. Kubes, and M.G. Swain Essential role for neutrophil recruitment to the liver in concanavalin A-induced hepatitis J Immunol 172 2004 45 53 (Pubitemid 38020454)
    • (2004) Journal of Immunology , vol.172 , Issue.1 , pp. 45-53
    • Bonder, C.S.1    Ajuebor, M.N.2    Zbytnuik, L.D.3    Kubes, P.4    Swain, M.G.5
  • 10
    • 79955021827 scopus 로고    scopus 로고
    • Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin a4 receptor and operative in the inflamed microvasculature
    • V. Brancaleone, J. Dalli, S. Bena, R.J. Flower, G. Cirino, and M. Perretti Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin a4 receptor and operative in the inflamed microvasculature J Immunol 186 2011 4905 4914
    • (2011) J Immunol , vol.186 , pp. 4905-4914
    • Brancaleone, V.1    Dalli, J.2    Bena, S.3    Flower, R.J.4    Cirino, G.5    Perretti, M.6
  • 11
    • 60749136484 scopus 로고    scopus 로고
    • An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
    • T. Burckstummer, C. Baumann, S. Bluml, E. Dixit, G. Durnberger, and H. Jahn An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome Nat Immunol 10 2009 266 272
    • (2009) Nat Immunol , vol.10 , pp. 266-272
    • Burckstummer, T.1    Baumann, C.2    Bluml, S.3    Dixit, E.4    Durnberger, G.5    Jahn, H.6
  • 12
    • 0026342111 scopus 로고
    • Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
    • E.C. Butcher Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity Cell 67 1991 1033 1036 (Pubitemid 121001517)
    • (1991) Cell , vol.67 , Issue.6 , pp. 1033-1036
    • Butcher, E.C.1
  • 13
    • 0031012331 scopus 로고    scopus 로고
    • Immunological induction of flavour aversion in mice. II. Passive/adoptive transfer and pharmacological inhibition
    • D.C. Cara, A.A. Conde, and N.M. Vaz Immunological induction of flavour aversion in mice. II. Passive/adoptive transfer and pharmacological inhibition Scand J Immunol 45 1997 16 20 (Pubitemid 27013962)
    • (1997) Scandinavian Journal of Immunology , vol.45 , Issue.1 , pp. 16-20
    • Cara, D.C.1    Conde, A.A.2    Vaz, N.M.3
  • 14
    • 0033929911 scopus 로고    scopus 로고
    • Mechanisms underlying eosinophil trafficking and their relevance in vivo
    • D.C. Cara, D. Negrao-Correa, and M.M. Teixeira Mechanisms underlying eosinophil trafficking and their relevance in vivo Histol Histopathol 15 2000 899 920 (Pubitemid 30495193)
    • (2000) Histology and Histopathology , vol.15 , Issue.3 , pp. 899-920
    • Cara, D.C.1    Negrao-Correa, D.2    Teixeira, M.M.3
  • 15
    • 0020062002 scopus 로고
    • Mitochondrial n-formylmethionyl proteins as chemoattractants for neutrophils
    • H. Carp Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils J Exp Med 155 1982 264 275 (Pubitemid 12209828)
    • (1982) Journal of Experimental Medicine , vol.155 , Issue.1 , pp. 264-275
    • Carp, H.1
  • 16
    • 79955559412 scopus 로고    scopus 로고
    • Genetic deletion or pharmacologic antagonism of LPA(1) ameliorates dermal fibrosis in a scleroderma mouse model
    • F.V. Castelino, J. Seiders, G. Bain, S.F. Brooks, C. King, and J.S. Swaney Genetic deletion or pharmacologic antagonism of LPA(1) ameliorates dermal fibrosis in a scleroderma mouse model Arthritis Rheum 63 5 2011 1405 1415
    • (2011) Arthritis Rheum , vol.63 , Issue.5 , pp. 1405-1415
    • Castelino, F.V.1    Seiders, J.2    Bain, G.3    Brooks, S.F.4    King, C.5    Swaney, J.S.6
  • 17
    • 58149149839 scopus 로고    scopus 로고
    • TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events
    • K.A. Cavassani, M. Ishii, H. Wen, M.A. Schaller, P.M. Lincoln, and N.W. Lukacs TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events J Exp Med 205 2008 2609 2621
    • (2008) J Exp Med , vol.205 , pp. 2609-2621
    • Cavassani, K.A.1    Ishii, M.2    Wen, H.3    Schaller, M.A.4    Lincoln, P.M.5    Lukacs, N.W.6
  • 19
    • 77957942834 scopus 로고    scopus 로고
    • Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis
    • F.B. Chekeni, M.R. Elliott, J.K. Sandilos, S.F. Walk, J.M. Kinchen, and E.R. Lazarowski Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis Nature 467 2010 863 867
    • (2010) Nature , vol.467 , pp. 863-867
    • Chekeni, F.B.1    Elliott, M.R.2    Sandilos, J.K.3    Walk, S.F.4    Kinchen, J.M.5    Lazarowski, E.R.6
  • 20
    • 78649526394 scopus 로고    scopus 로고
    • Sterile inflammation: Sensing and reacting to damage
    • G.Y. Chen, and G. Nunez Sterile inflammation: sensing and reacting to damage Nat Rev Immunol 10 2010 826 837
    • (2010) Nat Rev Immunol , vol.10 , pp. 826-837
    • Chen, G.Y.1    Nunez, G.2
  • 22
    • 34447116244 scopus 로고    scopus 로고
    • Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
    • DOI 10.1038/nm1603, PII NM1603
    • C.J. Chen, H. Kono, D. Golenbock, G. Reed, S. Akira, and K.L. Rock Identification of a key pathway required for the sterile inflammatory response triggered by dying cells Nat Med 13 2007 851 856 (Pubitemid 47038190)
    • (2007) Nature Medicine , vol.13 , Issue.7 , pp. 851-856
    • Chen, C.-J.1    Kono, H.2    Golenbock, D.3    Reed, G.4    Akira, S.5    Rock, K.L.6
  • 23
    • 68049092912 scopus 로고    scopus 로고
    • RNA polymerase III detects cytosolic DNA and induces type i interferons through the RIG-I pathway
    • Y.H. Chiu, J.B. Macmillan, and Z.J. Chen RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway Cell 138 2009 576 591
    • (2009) Cell , vol.138 , pp. 576-591
    • Chiu, Y.H.1    MacMillan, J.B.2    Chen, Z.J.3
  • 24
    • 0019934293 scopus 로고
    • Bleomycin-induced pulmonary fibrosis in hamsters: Effect of neutrophil depletion on lung collagen synthesis
    • J.G. Clark, and C. Kuhn 3rd. Bleomycin-induced pulmonary fibrosis in hamsters: effect of neutrophil depletion on lung collagen synthesis Am Rev Respir Dis 126 1982 737 739 (Pubitemid 12001435)
    • (1982) American Review of Respiratory Disease , vol.126 , Issue.4 , pp. 737-739
    • Clark, J.G.1    Kuhn III, C.2
  • 25
    • 67049114124 scopus 로고    scopus 로고
    • Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines
    • C. de la Motte, J. Nigro, A. Vasanji, H. Rho, S. Kessler, and S. Bandyopadhyay Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines Am J Pathol 174 2009 2254 2264
    • (2009) Am J Pathol , vol.174 , pp. 2254-2264
    • De La Motte, C.1    Nigro, J.2    Vasanji, A.3    Rho, H.4    Kessler, S.5    Bandyopadhyay, S.6
  • 26
    • 1542317550 scopus 로고    scopus 로고
    • Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
    • DOI 10.1126/science.1093616
    • S.S. Diebold, T. Kaisho, H. Hemmi, S. Akira, and C. Reis e Sousa Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA Science 303 2004 1529 1531 (Pubitemid 38314425)
    • (2004) Science , vol.303 , Issue.5663 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis E Sousa, C.5
  • 28
    • 77951800951 scopus 로고    scopus 로고
    • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
    • P. Duewell, H. Kono, K.J. Rayner, C.M. Sirois, G. Vladimer, and F.G. Bauernfeind NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals Nature 464 2010 1357 1361
    • (2010) Nature , vol.464 , pp. 1357-1361
    • Duewell, P.1    Kono, H.2    Rayner, K.J.3    Sirois, C.M.4    Vladimer, G.5    Bauernfeind, F.G.6
  • 29
    • 58849151813 scopus 로고    scopus 로고
    • Cutting edge: Critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells
    • T. Eigenbrod, J.H. Park, J. Harder, Y. Iwakura, and G. Nunez Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells J Immunol 181 2008 8194 8198
    • (2008) J Immunol , vol.181 , pp. 8194-8198
    • Eigenbrod, T.1    Park, J.H.2    Harder, J.3    Iwakura, Y.4    Nunez, G.5
  • 30
    • 70249090374 scopus 로고    scopus 로고
    • Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
    • M.R. Elliott, F.B. Chekeni, P.C. Trampont, E.R. Lazarowski, A. Kadl, and S.F. Walk Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance Nature 461 2009 282 286
    • (2009) Nature , vol.461 , pp. 282-286
    • Elliott, M.R.1    Chekeni, F.B.2    Trampont, P.C.3    Lazarowski, E.R.4    Kadl, A.5    Walk, S.F.6
  • 31
  • 33
    • 0022292384 scopus 로고
    • Two interferon-induced proteins are involved in the protein kinase complex dependent on double-stranded RNA
    • J. Galabru, and A.G. Hovanessian Two interferon-induced proteins are involved in the protein kinase complex dependent on double-stranded RNA Cell 43 1985 685 694
    • (1985) Cell , vol.43 , pp. 685-694
    • Galabru, J.1    Hovanessian, A.G.2
  • 34
    • 69549135324 scopus 로고    scopus 로고
    • Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
    • D. Ganguly, G. Chamilos, R. Lande, J. Gregorio, S. Meller, and V. Facchinetti Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8 J Exp Med 206 2009 1983 1994
    • (2009) J Exp Med , vol.206 , pp. 1983-1994
    • Ganguly, D.1    Chamilos, G.2    Lande, R.3    Gregorio, J.4    Meller, S.5    Facchinetti, V.6
  • 35
    • 79955649371 scopus 로고    scopus 로고
    • The development of anti-inflammatory drugs for infectious diseases
    • C.C. Garcia, R. Guabiraba, F.M. Soriani, and M.M. Teixeira The development of anti-inflammatory drugs for infectious diseases Discov Med 10 2010 479 488
    • (2010) Discov Med , vol.10 , pp. 479-488
    • Garcia, C.C.1    Guabiraba, R.2    Soriani, F.M.3    Teixeira, M.M.4
  • 36
    • 79251512615 scopus 로고    scopus 로고
    • Platelet-activating factor receptor plays a role in lung injury and death caused by Influenza A in mice
    • C.C. Garcia, R.C. Russo, R. Guabiraba, C.T. Fagundes, R.B. Polidoro, and L.P. Tavares Platelet-activating factor receptor plays a role in lung injury and death caused by Influenza A in mice PLoS Pathog 6 2010 e1001171
    • (2010) PLoS Pathog , vol.6 , pp. 1001171
    • Garcia, C.C.1    Russo, R.C.2    Guabiraba, R.3    Fagundes, C.T.4    Polidoro, R.B.5    Tavares, L.P.6
  • 38
    • 48549088455 scopus 로고    scopus 로고
    • Antimicrobial peptides and self-DNA in autoimmune skin inflammation
    • M. Gilliet, and R. Lande Antimicrobial peptides and self-DNA in autoimmune skin inflammation Curr Opin Immunol 20 2008 401 407
    • (2008) Curr Opin Immunol , vol.20 , pp. 401-407
    • Gilliet, M.1    Lande, R.2
  • 39
    • 0041350372 scopus 로고    scopus 로고
    • Novel Pharmacological Approaches to Manage Interstitial Lung Fibrosis in the Twenty-First Century
    • DOI 10.1146/annurev.pharmtox.43.100901.135740
    • S.N. Giri Novel pharmacological approaches to manage interstitial lung fibrosis in the twenty-first century Annu Rev Pharmacol Toxicol 43 2003 73 95 (Pubitemid 37372635)
    • (2003) Annual Review of Pharmacology and Toxicology , vol.43 , pp. 73-95
    • Giri, S.N.1
  • 40
    • 48749121214 scopus 로고    scopus 로고
    • Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal
    • D.R. Gude, S.E. Alvarez, S.W. Paugh, P. Mitra, J. Yu, and R. Griffiths Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal FASEB J 22 2008 2629 2638
    • (2008) FASEB J , vol.22 , pp. 2629-2638
    • Gude, D.R.1    Alvarez, S.E.2    Paugh, S.W.3    Mitra, P.4    Yu, J.5    Griffiths, R.6
  • 41
    • 40249088259 scopus 로고    scopus 로고
    • The DNA Sugar Backbone 2′ Deoxyribose Determines Toll-like Receptor 9 Activation
    • DOI 10.1016/j.immuni.2008.01.013, PII S1074761308000770
    • T. Haas, J. Metzger, F. Schmitz, A. Heit, T. Muller, and E. Latz The DNA sugar backbone 2′ deoxyribose determines toll-like receptor 9 activation Immunity 28 2008 315 323 (Pubitemid 351335308)
    • (2008) Immunity , vol.28 , Issue.3 , pp. 315-323
    • Haas, T.1    Metzger, J.2    Schmitz, F.3    Heit, A.4    Muller, T.5    Latz, E.6    Wagner, H.7
  • 45
    • 65349104899 scopus 로고    scopus 로고
    • Intravascular immunity: The host-pathogen encounter in blood vessels
    • M.J. Hickey, and P. Kubes Intravascular immunity: the host-pathogen encounter in blood vessels Nat Rev Immunol 9 2009 364 375
    • (2009) Nat Rev Immunol , vol.9 , pp. 364-375
    • Hickey, M.J.1    Kubes, P.2
  • 49
    • 17844380477 scopus 로고    scopus 로고
    • Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
    • DOI 10.1038/nature03547
    • K. Honda, Y. Ohba, H. Yanai, H. Negishi, T. Mizutani, and A. Takaoka Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction Nature 434 2005 1035 1040 (Pubitemid 40586053)
    • (2005) Nature , vol.434 , Issue.7036 , pp. 1035-1040
    • Honda, K.1    Ohba, Y.2    Yanai, H.3    Hegishi, H.4    Mizutani, T.5    Takaoka, A.6    Taya, C.7    Taniguchi, T.8
  • 51
    • 75649106430 scopus 로고    scopus 로고
    • Intracellular DNA recognition
    • V. Hornung, and E. Latz Intracellular DNA recognition Nat Rev Immunol 10 2010 123 130
    • (2010) Nat Rev Immunol , vol.10 , pp. 123-130
    • Hornung, V.1    Latz, E.2
  • 53
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • V. Hornung, F. Bauernfeind, A. Halle, E.O. Samstad, H. Kono, and K.L. Rock Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization Nat Immunol 9 2008 847 856
    • (2008) Nat Immunol , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5    Rock, K.L.6
  • 56
    • 18644386509 scopus 로고    scopus 로고
    • Autoimmune thyroid disease (Grave's disease and Hashimoto's thyroiditis) in two patients with Crohn's disease: Case reports and literature review
    • DOI 10.2169/internalmedicine.44.303
    • T. Inokuchi, Y. Moriwaki, S. Takahashi, Z. Tsutsumi, T. Ka, and T. Yamamoto Autoimmune thyroid disease (Graves' disease and hashimoto's thyroiditis) in two patients with Crohn's disease: case reports and literature review Intern Med 44 2005 303 306 (Pubitemid 40663031)
    • (2005) Internal Medicine , vol.44 , Issue.4 , pp. 303-306
    • Inokuchi, T.1    Moriwaki, Y.2    Takahashi, S.3    Tsutsumi, Z.4    Ka, T.5    Yamamoto, T.6
  • 60
    • 34250310047 scopus 로고    scopus 로고
    • Neutrophil depletion protects against murine acetaminophen hepatotoxicity: Another perspective [7]
    • DOI 10.1002/hep.21549
    • H. Jaeschke, and J. Liu Neutrophil depletion protects against murine acetaminophen hepatotoxicity: another perspective Hepatology 45 2007 1588 1589 author reply 1589 (Pubitemid 46918350)
    • (2007) Hepatology , vol.45 , Issue.6 , pp. 1588-1589
    • Jaeschke, H.1    Liu, J.2
  • 61
    • 33846673312 scopus 로고    scopus 로고
    • Alcoholic pancreatitis: Mechanisms of viral infections as cofactors in the development of acute and chronic pancreatitis and fibrosis
    • DOI 10.1189/jlb.1004622
    • T.R. Jerrells, D. Vidlak, and J.M. Strachota Alcoholic pancreatitis: mechanisms of viral infections as cofactors in the development of acute and chronic pancreatitis and fibrosis J Leukoc Biol 81 2007 430 439 (Pubitemid 46198394)
    • (2007) Journal of Leukocyte Biology , vol.81 , Issue.2 , pp. 430-439
    • Jerrells, T.R.1    Vidlak, D.2    Strachota, J.M.3
  • 63
    • 34247118826 scopus 로고    scopus 로고
    • Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling
    • DOI 10.1016/j.immuni.2007.03.008, PII S1074761307002117
    • T.D. Kanneganti, M. Lamkanfi, Y.G. Kim, G. Chen, J.H. Park, and L. Franchi Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling Immunity 26 2007 433 443 (Pubitemid 46603000)
    • (2007) Immunity , vol.26 , Issue.4 , pp. 433-443
    • Kanneganti, T.-D.1    Lamkanfi, M.2    Kim, Y.-G.3    Chen, G.4    Park, J.-H.5    Franchi, L.6    Vandenabeele, P.7    Nunez, G.8
  • 64
    • 0028520285 scopus 로고
    • Ischemia/reperfusion-induced granulocyte influx is a multistep process mediated by mast cells
    • S. Kanwar, and P. Kubes Ischemia/reperfusion-induced granulocyte influx is a multistep process mediated by mast cells Microcirculation 1 1994 175 182
    • (1994) Microcirculation , vol.1 , pp. 175-182
    • Kanwar, S.1    Kubes, P.2
  • 65
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • T. Kawai, and S. Akira The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors Nat Immunol 11 2010 373 384
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 67
    • 58149269348 scopus 로고    scopus 로고
    • Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
    • S. Kim, H. Takahashi, W.W. Lin, P. Descargues, S. Grivennikov, and Y. Kim Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis Nature 457 2009 102 106
    • (2009) Nature , vol.457 , pp. 102-106
    • Kim, S.1    Takahashi, H.2    Lin, W.W.3    Descargues, P.4    Grivennikov, S.5    Kim, Y.6
  • 68
    • 77953187290 scopus 로고    scopus 로고
    • Uric acid promotes an acute inflammatory response to sterile cell death in mice
    • H. Kono, C.J. Chen, F. Ontiveros, and K.L. Rock Uric acid promotes an acute inflammatory response to sterile cell death in mice J Clin Invest 120 2010 1939 1949
    • (2010) J Clin Invest , vol.120 , pp. 1939-1949
    • Kono, H.1    Chen, C.J.2    Ontiveros, F.3    Rock, K.L.4
  • 69
    • 0029932729 scopus 로고    scopus 로고
    • Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA
    • A.M. Krieg Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA Trends Microbiol 4 1996 73 76
    • (1996) Trends Microbiol , vol.4 , pp. 73-76
    • Krieg, A.M.1
  • 70
    • 0030777513 scopus 로고    scopus 로고
    • The role of shear forces in ischemia/reperfusion-induced neutrophil rolling and adhesion
    • P. Kubes The role of shear forces in ischemia/reperfusion-induced neutrophil rolling and adhesion J Leukoc Biol 62 1997 458 464 (Pubitemid 27459774)
    • (1997) Journal of Leukocyte Biology , vol.62 , Issue.4 , pp. 458-464
    • Kubes, P.1
  • 71
    • 0033027832 scopus 로고    scopus 로고
    • The role of adhesion molecules and nitric oxide in intestinal and hepatic ischemia/reperfusion
    • P. Kubes The role of adhesion molecules and nitric oxide in intestinal and hepatic ischemia/reperfusion Hepatogastroenterology 46 Suppl. 2 1999 1458 1463 (Pubitemid 29313185)
    • (1999) Hepato-Gastroenterology , vol.46 , Issue.SUPPL. 2 , pp. 1458-1463
    • Kubes, P.1
  • 72
    • 0029048793 scopus 로고
    • Therapeutic potential of inhibiting leukocyte rolling in ischemia/reperfusion
    • P. Kubes, M. Jutila, and D. Payne Therapeutic potential of inhibiting leukocyte rolling in ischemia/reperfusion J Clin Invest 95 1995 2510 2519
    • (1995) J Clin Invest , vol.95 , pp. 2510-2519
    • Kubes, P.1    Jutila, M.2    Payne, D.3
  • 76
    • 0037061453 scopus 로고    scopus 로고
    • Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
    • DOI 10.1038/416603a
    • E.A. Leadbetter, I.R. Rifkin, A.M. Hohlbaum, B.C. Beaudette, M.J. Shlomchik, and A. Marshak-Rothstein Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors Nature 416 2002 603 607 (Pubitemid 34406754)
    • (2002) Nature , vol.416 , Issue.6881 , pp. 603-607
    • Leadbetter, E.A.1    Rifkin, I.R.2    Hohlbaum, A.M.3    Beaudette, B.C.4    Shlomchik, M.J.5    Marshak-Rothstein, A.6
  • 77
    • 39149130710 scopus 로고    scopus 로고
    • Leukocyte adhesion in the liver: Distinct adhesion paradigm from other organs
    • W.Y. Lee, and P. Kubes Leukocyte adhesion in the liver: distinct adhesion paradigm from other organs J Hepatol 48 2008 504 512
    • (2008) J Hepatol , vol.48 , pp. 504-512
    • Lee, W.Y.1    Kubes, P.2
  • 78
    • 34548230927 scopus 로고    scopus 로고
    • Getting to the site of inflammation: The leukocyte adhesion cascade updated
    • DOI 10.1038/nri2156, PII NRI2156
    • K. Ley, C. Laudanna, M.I. Cybulsky, and S. Nourshargh Getting to the site of inflammation: the leukocyte adhesion cascade updated Nat Rev Immunol 7 2007 678 689 (Pubitemid 47327397)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.9 , pp. 678-689
    • Ley, K.1    Laudanna, C.2    Cybulsky, M.I.3    Nourshargh, S.4
  • 79
    • 77956524295 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury
    • P. Li, H.D. Xiao, J. Xu, F.S. Ong, M. Kwon, J. Roman, A. Gal, K.E. Bernstein, and S. Fuchs Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury Am J Pathol 177 2010 1113 1121
    • (2010) Am J Pathol , vol.177 , pp. 1113-1121
    • Li, P.1    Xiao, H.D.2    Xu, J.3    Ong, F.S.4    Kwon, M.5    Roman, J.6    Gal, A.7    Bernstein, K.E.8    Fuchs, S.9
  • 80
    • 0032421440 scopus 로고    scopus 로고
    • Bacterial DNA as immune cell activator
    • DOI 10.1016/S0966-842X(98)01408-5, PII S0966842X98014085
    • G.B. Lipford, K. Heeg, and H. Wagner Bacterial DNA as immune cell activator Trends Microbiol 6 1998 496 500 (Pubitemid 29002883)
    • (1998) Trends in Microbiology , vol.6 , Issue.12 , pp. 496-500
    • Lipford, G.B.1    Heeg, K.2    Wagner, H.3
  • 81
    • 33745549377 scopus 로고    scopus 로고
    • Neutrophil depletion protects against murine acetaminophen hepatotoxicity
    • DOI 10.1002/hep.21175
    • Z.X. Liu, D. Han, B. Gunawan, and N. Kaplowitz Neutrophil depletion protects against murine acetaminophen hepatotoxicity Hepatology 43 2006 1220 1230 (Pubitemid 43980100)
    • (2006) Hepatology , vol.43 , Issue.6 , pp. 1220-1230
    • Liu, Z.-X.1    Han, D.2    Gunawan, B.3    Kaplowitz, N.4
  • 83
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • DOI 10.1038/nature04516, PII N04516
    • F. Martinon, V. Petrilli, A. Mayor, A. Tardivel, and J. Tschopp Gout-associated uric acid crystals activate the NALP3 inflammasome Nature 440 2006 237 241 (Pubitemid 43372104)
    • (2006) Nature , vol.440 , Issue.7081 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 84
    • 77956958947 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes
    • S.L. Masters, A. Dunne, S.L. Subramanian, R.L. Hull, G.M. Tannahill, and F.A. Sharp Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes Nat Immunol 11 2010 897 904
    • (2010) Nat Immunol , vol.11 , pp. 897-904
    • Masters, S.L.1    Dunne, A.2    Subramanian, S.L.3    Hull, R.L.4    Tannahill, G.M.5    Sharp, F.A.6
  • 85
    • 0028365722 scopus 로고
    • Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat: Effects of neutrophil depletion
    • Y. Matsuo, H. Onodera, Y. Shiga, M. Nakamura, M. Ninomiya, T. Kihara, and K. Kogure Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat Effects of neutrophil depletion. Stroke 25 1994 1469 1475 (Pubitemid 24198597)
    • (1994) Stroke , vol.25 , Issue.7 , pp. 1469-1475
    • Matsuo, Y.1    Onodera, H.2    Shiga, Y.3    Nakamura, M.4    Ninomiya, M.5    Kihara, T.6    Kogure, K.7
  • 86
    • 0032400984 scopus 로고    scopus 로고
    • Treatment with anti-granulocyte antibodies inhibits the effector phase of experimental autoimmune encephalomyelitis
    • S.R. McColl, M.A. Staykova, A. Wozniak, S. Fordham, J. Bruce, and D.O. Willenborg Treatment with anti-granulocyte antibodies inhibits the effector phase of experimental autoimmune encephalomyelitis J Immunol 161 1998 6421 6426 (Pubitemid 28536020)
    • (1998) Journal of Immunology , vol.161 , Issue.11 , pp. 6421-6426
    • McColl, S.R.1    Staykova, M.A.2    Wozniak, A.3    Fordham, S.4    Bruce, J.5    Willenborg, D.O.6
  • 89
    • 66949122854 scopus 로고    scopus 로고
    • Approaching the asymptote: 20 years later
    • R. Medzhitov Approaching the asymptote: 20 years later Immunity 30 2009 766 775
    • (2009) Immunity , vol.30 , pp. 766-775
    • Medzhitov, R.1
  • 90
    • 67049172095 scopus 로고    scopus 로고
    • Hyaluronan, platelets, and monocytes: A novel pro-inflammatory triad
    • G.B. Menezes, E.F. McAvoy, and P. Kubes Hyaluronan, platelets, and monocytes: a novel pro-inflammatory triad Am J Pathol 174 2009 1993 1995
    • (2009) Am J Pathol , vol.174 , pp. 1993-1995
    • Menezes, G.B.1    McAvoy, E.F.2    Kubes, P.3
  • 91
    • 27144440476 scopus 로고    scopus 로고
    • Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
    • DOI 10.1038/nature04193, PII N04193
    • E. Meylan, J. Curran, K. Hofmann, D. Moradpour, M. Binder, and R. Bartenschlager Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus Nature 437 2005 1167 1172 (Pubitemid 41509355)
    • (2005) Nature , vol.437 , Issue.7062 , pp. 1167-1172
    • Meylan, E.1    Curran, J.2    Hofmann, K.3    Moradpour, D.4    Binder, M.5    Bartenschlager, R.6    Tschopp, J.7
  • 92
    • 33751211223 scopus 로고    scopus 로고
    • Formyl peptide receptors: A promiscuous subfamily of G protein-coupled receptors controlling immune responses
    • DOI 10.1016/j.cytogfr.2006.09.009, PII S135961010600058X
    • I. Migeotte, D. Communi, and M. Parmentier Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses Cytokine Growth Factor Rev 17 2006 501 519 (Pubitemid 44793122)
    • (2006) Cytokine and Growth Factor Reviews , vol.17 , Issue.6 , pp. 501-519
    • Migeotte, I.1    Communi, D.2    Parmentier, M.3
  • 93
    • 0026601706 scopus 로고
    • Comparison of the University of Wisconsin preservation solution and other crystalloid perfusates in a 30-hour rabbit lung preservation model
    • S. Miyoshi, S. Shimokawa, H. Schreinemakers, H. Date, W. Weder, and B. Harper Comparison of the University of Wisconsin preservation solution and other crystalloid perfusates in a 30-hour rabbit lung preservation model J Thorac Cardiovasc Surg 103 1992 27 32
    • (1992) J Thorac Cardiovasc Surg , vol.103 , pp. 27-32
    • Miyoshi, S.1    Shimokawa, S.2    Schreinemakers, H.3    Date, H.4    Weder, W.5    Harper, B.6
  • 94
    • 78649856319 scopus 로고    scopus 로고
    • The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis
    • K. Moreth, R. Brodbeck, A. Babelova, N. Gretz, T. Spieker, and J. Zeng-Brouwers The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis J Clin Invest 120 2010 4251 4272
    • (2010) J Clin Invest , vol.120 , pp. 4251-4272
    • Moreth, K.1    Brodbeck, R.2    Babelova, A.3    Gretz, N.4    Spieker, T.5    Zeng-Brouwers, J.6
  • 96
    • 77953350982 scopus 로고    scopus 로고
    • Monocytes: Protagonists of infarct inflammation and repair after myocardial infarction
    • M. Nahrendorf, M.J. Pittet, and F.K. Swirski Monocytes: protagonists of infarct inflammation and repair after myocardial infarction Circulation 121 2010 2437 2445
    • (2010) Circulation , vol.121 , pp. 2437-2445
    • Nahrendorf, M.1    Pittet, M.J.2    Swirski, F.K.3
  • 97
    • 79951642032 scopus 로고    scopus 로고
    • Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
    • K. Nakahira, J.A. Haspel, V.A. Rathinam, S.J. Lee, T. Dolinay, and H.C. Lam Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome Nat Immunol 12 2010 222 230
    • (2010) Nat Immunol , vol.12 , pp. 222-230
    • Nakahira, K.1    Haspel, J.A.2    Rathinam, V.A.3    Lee, S.J.4    Dolinay, T.5    Lam, H.C.6
  • 98
    • 0034114882 scopus 로고    scopus 로고
    • Features of systemic lupus erythematosus in Dnase1-deficient mice
    • DOI 10.1038/76032
    • M. Napirei, H. Karsunky, B. Zevnik, H. Stephan, H.G. Mannherz, and T. Moroy Features of systemic lupus erythematosus in Dnase1-deficient mice Nat Genet 25 2000 177 181 (Pubitemid 30394988)
    • (2000) Nature Genetics , vol.25 , Issue.2 , pp. 177-181
    • Napirei, M.1    Karsunky, H.2    Zevnik, B.3    Stephan, H.4    Mannherz, H.G.5    Moroy, T.6
  • 99
    • 55349123588 scopus 로고    scopus 로고
    • Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells
    • G. Ng, K. Sharma, S.M. Ward, M.D. Desrosiers, L.A. Stephens, and W.M. Schoel Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells Immunity 29 2008 807 818
    • (2008) Immunity , vol.29 , pp. 807-818
    • Ng, G.1    Sharma, K.2    Ward, S.M.3    Desrosiers, M.D.4    Stephens, L.A.5    Schoel, W.M.6
  • 100
    • 27944453599 scopus 로고    scopus 로고
    • Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
    • DOI 10.1084/jem.20051654
    • Y. Okabe, K. Kawane, S. Akira, T. Taniguchi, and S. Nagata Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation J Exp Med 202 2005 1333 1339 (Pubitemid 41668736)
    • (2005) Journal of Experimental Medicine , vol.202 , Issue.10 , pp. 1333-1339
    • Okabe, Y.1    Kawane, K.2    Akira, S.3    Taniguchi, T.4    Nagata, S.5
  • 101
    • 77950476766 scopus 로고    scopus 로고
    • Sensing and signaling in antiviral innate immunity
    • L.A. O'Neill, and A.G. Bowie Sensing and signaling in antiviral innate immunity Curr Biol 20 2010 R328 R333
    • (2010) Curr Biol , vol.20
    • O'Neill, L.A.1    Bowie, A.G.2
  • 103
    • 78650674088 scopus 로고    scopus 로고
    • Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus
    • R. Panchanathan, X. Duan, H. Shen, V.A. Rathinam, L.D. Erickson, and K.A. Fitzgerald Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus J Immunol 185 2010 7385 7393
    • (2010) J Immunol , vol.185 , pp. 7385-7393
    • Panchanathan, R.1    Duan, X.2    Shen, H.3    Rathinam, V.A.4    Erickson, L.D.5    Fitzgerald, K.A.6
  • 104
    • 32044459729 scopus 로고    scopus 로고
    • Neutrophils regulate airway responses in a model of fungal allergic airways disease
    • S.J. Park, M.T. Wiekowski, S.A. Lira, and B. Mehrad Neutrophils regulate airway responses in a model of fungal allergic airways disease J Immunol 176 2006 2538 2545 (Pubitemid 43201705)
    • (2006) Journal of Immunology , vol.176 , Issue.4 , pp. 2538-2545
    • Park, S.J.1    Wiekowski, M.T.2    Lira, S.A.3    Mehrad, B.4
  • 105
    • 45549106551 scopus 로고    scopus 로고
    • The physiology of leukocyte recruitment: An in vivo perspective
    • B. Petri, M. Phillipson, and P. Kubes The physiology of leukocyte recruitment: an in vivo perspective J Immunol 180 2008 6439 6446
    • (2008) J Immunol , vol.180 , pp. 6439-6446
    • Petri, B.1    Phillipson, M.2    Kubes, P.3
  • 106
    • 33750984771 scopus 로고    scopus 로고
    • RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates
    • DOI 10.1126/science.1132998
    • A. Pichlmair, O. Schulz, C.P. Tan, T.I. Naslund, P. Liljestrom, and F. Weber RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates Science 314 2006 997 1001 (Pubitemid 44749946)
    • (2006) Science , vol.314 , Issue.5801 , pp. 997-1001
    • Pichlmair, A.1    Schulz, O.2    Tan, C.P.3    Naslund, T.I.4    Liljestrom, P.5    Weber, F.6    Reis E Sousa, C.7
  • 108
    • 47649126069 scopus 로고    scopus 로고
    • Allergy as an organ and a systemic disease
    • DOI 10.1111/j.1365-2249.2008.03712.x
    • S. Pucci, and C. Incorvaia Allergy as an organ and a systemic disease Clin Exp Immunol 153 Suppl. 1 2008 1 2 (Pubitemid 352020374)
    • (2008) Clinical and Experimental Immunology , vol.153 , Issue.SUPPL. 1 , pp. 1-2
    • Pucci, S.1    Incorvaia, C.2
  • 109
    • 34548614009 scopus 로고    scopus 로고
    • Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
    • Y. Qu, L. Franchi, G. Nunez, and G.R. Dubyak Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages J Immunol 179 2007 1913 1925
    • (2007) J Immunol , vol.179 , pp. 1913-1925
    • Qu, Y.1    Franchi, L.2    Nunez, G.3    Dubyak, G.R.4
  • 110
    • 65249164404 scopus 로고    scopus 로고
    • P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1
    • Y. Qu, L. Ramachandra, S. Mohr, L. Franchi, C.V. Harding, and G. Nunez P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1 J Immunol 182 2009 5052 5062
    • (2009) J Immunol , vol.182 , pp. 5052-5062
    • Qu, Y.1    Ramachandra, L.2    Mohr, S.3    Franchi, L.4    Harding, C.V.5    Nunez, G.6
  • 112
    • 35348983904 scopus 로고    scopus 로고
    • Role of neutrophils in the pathogenesis of acute inflammatory liver injury
    • DOI 10.1080/01926230701584163, PII 783022137
    • S.K. Ramaiah, and H. Jaeschke Role of neutrophils in the pathogenesis of acute inflammatory liver injury Toxicol Pathol 35 2007 757 766 (Pubitemid 47613608)
    • (2007) Toxicologic Pathology , vol.35 , Issue.6 , pp. 757-766
    • Ramaiah, S.K.1    Jaeschke, H.2
  • 113
    • 77951269392 scopus 로고    scopus 로고
    • The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
    • V.A. Rathinam, Z. Jiang, S.N. Waggoner, S. Sharma, L.E. Cole, and L. Waggoner The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses Nat Immunol 11 2010 395 402
    • (2010) Nat Immunol , vol.11 , pp. 395-402
    • Rathinam, V.A.1    Jiang, Z.2    Waggoner, S.N.3    Sharma, S.4    Cole, L.E.5    Waggoner, L.6
  • 114
    • 77956255766 scopus 로고    scopus 로고
    • Find-me and eat-me signals in apoptotic cell clearance: Progress and conundrums
    • K.S. Ravichandran Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums J Exp Med 207 2010 1807 1817
    • (2010) J Exp Med , vol.207 , pp. 1807-1817
    • Ravichandran, K.S.1
  • 115
    • 75749140581 scopus 로고    scopus 로고
    • RIG-I detects viral genomic RNA during negative-strand RNA virus infection
    • J. Rehwinkel, C.P. Tan, D. Goubau, O. Schulz, A. Pichlmair, and K. Bier RIG-I detects viral genomic RNA during negative-strand RNA virus infection Cell 140 2010 397 408
    • (2010) Cell , vol.140 , pp. 397-408
    • Rehwinkel, J.1    Tan, C.P.2    Goubau, D.3    Schulz, O.4    Pichlmair, A.5    Bier, K.6
  • 116
  • 120
    • 77954650443 scopus 로고    scopus 로고
    • Anti-inflammatory drug development: Broad or specific chemokine receptor antagonists?
    • R.C. Russo, C.C. Garcia, and M.M. Teixeira Anti-inflammatory drug development: broad or specific chemokine receptor antagonists? Curr Opin Drug Discov Devel 13 2010 414 427
    • (2010) Curr Opin Drug Discov Devel , vol.13 , pp. 414-427
    • Russo, R.C.1    Garcia, C.C.2    Teixeira, M.M.3
  • 123
    • 0033680737 scopus 로고    scopus 로고
    • Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction
    • M. Sato, H. Suemori, N. Hata, M. Asagiri, K. Ogasawara, and K. Nakao Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction Immunity 13 2000 539 548
    • (2000) Immunity , vol.13 , pp. 539-548
    • Sato, M.1    Suemori, H.2    Hata, N.3    Asagiri, M.4    Ogasawara, K.5    Nakao, K.6
  • 126
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • K. Schroder, and J. Tschopp The inflammasomes Cell 140 2010 821 832
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 127
    • 74549184092 scopus 로고    scopus 로고
    • The NLRP3 inflammasome: A sensor for metabolic danger?
    • K. Schroder, R. Zhou, and J. Tschopp The NLRP3 inflammasome: a sensor for metabolic danger? Science 327 2010 296 300
    • (2010) Science , vol.327 , pp. 296-300
    • Schroder, K.1    Zhou, R.2    Tschopp, J.3
  • 128
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3
    • DOI 10.1016/j.cell.2005.08.012, PII S0092867405008160
    • R.B. Seth, L. Sun, C.K. Ea, and Z.J. Chen Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3 Cell 122 2005 669 682 (Pubitemid 41242633)
    • (2005) Cell , vol.122 , Issue.5 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.-K.3    Chen, Z.J.4
  • 129
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • DOI 10.1038/nature01991
    • Y. Shi, J.E. Evans, and K.L. Rock Molecular identification of a danger signal that alerts the immune system to dying cells Nature 425 2003 516 521 (Pubitemid 37237047)
    • (2003) Nature , vol.425 , Issue.6957 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 130
    • 18744405455 scopus 로고    scopus 로고
    • Myasthenia gravis: Emerging new therapy options
    • DOI 10.1016/j.coph.2005.01.010, PII S1471489205000329
    • J.P. Sieb Myasthenia gravis: emerging new therapy options Curr Opin Pharmacol 5 2005 303 307 (Pubitemid 40674254)
    • (2005) Current Opinion in Pharmacology , vol.5 , Issue.3 SPEC. ISS. , pp. 303-307
    • Sieb, J.P.1
  • 132
    • 0035451118 scopus 로고    scopus 로고
    • Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4
    • S.T. Smiley, J.A. King, and W.W. Hancock Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4 J Immunol 167 2001 2887 2894 (Pubitemid 32768923)
    • (2001) Journal of Immunology , vol.167 , Issue.5 , pp. 2887-2894
    • Smiley, S.T.1    King, J.A.2    Hancock, W.W.3
  • 133
    • 34047174085 scopus 로고    scopus 로고
    • A pilot study of IL-1 inhibition by anakinra in acute gout
    • A. So, T. De Smedt, S. Revaz, and J. Tschopp A pilot study of IL-1 inhibition by anakinra in acute gout Arthritis Res Ther 9 2007 R28
    • (2007) Arthritis Res Ther , vol.9 , pp. 28
    • So, A.1    De Smedt, T.2    Revaz, S.3    Tschopp, J.4
  • 135
    • 0035167833 scopus 로고    scopus 로고
    • Effects of inhibition of PDE4 and TNF-α on local and remote injuries following ischaemia and reperfusion injury
    • D.G. Souza, G.D. Cassali, S. Poole, and M.M. Teixeira Effects of inhibition of PDE4 and TNF-alpha on local and remote injuries following ischaemia and reperfusion injury Br J Pharmacol 134 2001 985 994 (Pubitemid 33052157)
    • (2001) British Journal of Pharmacology , vol.134 , Issue.5 , pp. 985-994
    • Souza, D.G.1    Cassali, G.D.2    Poole, S.3    Teixeira, M.M.4
  • 136
    • 0037023582 scopus 로고    scopus 로고
    • Effect of a BLT receptor antagonist in a model of severe ischemia and reperfusion injury in the rat
    • DOI 10.1016/S0014-2999(02)01313-4, PII S0014299902013134
    • D.G. Souza, V. Pinho, G.D. Cassali, S. Poole, and M.M. Teixeira Effect of a BLT receptor antagonist in a model of severe ischemia and reperfusion injury in the rat Eur J Pharmacol 440 2002 61 69 (Pubitemid 34312039)
    • (2002) European Journal of Pharmacology , vol.440 , Issue.1 , pp. 61-69
    • Souza, D.G.1    Pinho, V.2    Cassali, G.D.3    Poole, S.4    Teixeira, M.M.5
  • 138
    • 0038340319 scopus 로고    scopus 로고
    • Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatment
    • DOI 10.1038/sj.bjp.0705296
    • D.G. Souza, V. Pinho, A.C. Soares, T. Shimizu, S. Ishii, and M.M. Teixeira Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatment Br J Pharmacol 139 2003 733 740 (Pubitemid 36819600)
    • (2003) British Journal of Pharmacology , vol.139 , Issue.4 , pp. 733-740
    • Souza, D.G.1    Pinho, V.2    Soares, A.C.3    Shimizu, T.4    Ishii, S.5    Teixeira, M.M.6
  • 139
    • 4644280675 scopus 로고    scopus 로고
    • Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury
    • DOI 10.1038/sj.bjp.0705862
    • D.G. Souza, R. Bertini, A.T. Vieira, F.Q. Cunha, S. Poole, and M. Allegretti Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury Br J Pharmacol 143 2004 132 142 (Pubitemid 39280032)
    • (2004) British Journal of Pharmacology , vol.143 , Issue.1 , pp. 132-142
    • Souza, D.G.1    Bertini, R.2    Vieira, A.T.3    Cunha, F.Q.4    Poole, S.5    Allegretti, M.6    Colotta, F.7    Teixeira, M.M.8
  • 140
    • 0842300351 scopus 로고    scopus 로고
    • 1 Receptors in the Local, Remote, and Systemic Inflammatory Responses that Follow Intestinal Ischemia and Reperfusion Injury
    • D.G. Souza, E.S. Lomez, V. Pinho, J.B. Pesquero, M. Bader, and J.L. Pesquero Role of bradykinin B2 and B1 receptors in the local, remote, and systemic inflammatory responses that follow intestinal ischemia and reperfusion injury J Immunol 172 2004 2542 2548 (Pubitemid 38182405)
    • (2004) Journal of Immunology , vol.172 , Issue.4 , pp. 2542-2548
    • Souza, D.G.1    Lomez, E.S.L.2    Pinho, V.3    Pesquero, J.B.4    Bader, M.5    Pesquero, J.L.6    Teixeira, M.M.7
  • 141
    • 65349086167 scopus 로고    scopus 로고
    • The long pentraxin PTX3 is crucial for tissue inflammation after intestinal ischemia and reperfusion in mice
    • D.G. Souza, F.A. Amaral, C.T. Fagundes, F.M. Coelho, R.M. Arantes, and L.P. Sousa The long pentraxin PTX3 is crucial for tissue inflammation after intestinal ischemia and reperfusion in mice Am J Pathol 174 2009 1309 1318
    • (2009) Am J Pathol , vol.174 , pp. 1309-1318
    • Souza, D.G.1    Amaral, F.A.2    Fagundes, C.T.3    Coelho, F.M.4    Arantes, R.M.5    Sousa, L.P.6
  • 142
    • 69549133921 scopus 로고    scopus 로고
    • Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection
    • D.G. Souza, C.T. Fagundes, L.P. Sousa, F.A. Amaral, R.S. Souza, and A.L. Souza Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection Proc Natl Acad Sci U S A 106 2009 14138 14143
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14138-14143
    • Souza, D.G.1    Fagundes, C.T.2    Sousa, L.P.3    Amaral, F.A.4    Souza, R.S.5    Souza, A.L.6
  • 143
    • 67049134634 scopus 로고    scopus 로고
    • Connections between antiviral defense and autoimmunity
    • D.B. Stetson Connections between antiviral defense and autoimmunity Curr Opin Immunol 21 2009 244 250
    • (2009) Curr Opin Immunol , vol.21 , pp. 244-250
    • Stetson, D.B.1
  • 144
    • 30444450839 scopus 로고    scopus 로고
    • Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
    • DOI 10.1016/j.immuni.2005.12.003, PII S1074761305004115
    • D.B. Stetson, and R. Medzhitov Recognition of cytosolic DNA activates an IRF3-dependent innate immune response Immunity 24 2006 93 103 (Pubitemid 43077203)
    • (2006) Immunity , vol.24 , Issue.1 , pp. 93-103
    • Stetson, D.B.1    Medzhitov, R.2
  • 145
    • 49549100511 scopus 로고    scopus 로고
    • Trex1 prevents cell-intrinsic initiation of autoimmunity
    • D.B. Stetson, J.S. Ko, T. Heidmann, and R. Medzhitov Trex1 prevents cell-intrinsic initiation of autoimmunity Cell 134 2008 587 598
    • (2008) Cell , vol.134 , pp. 587-598
    • Stetson, D.B.1    Ko, J.S.2    Heidmann, T.3    Medzhitov, R.4
  • 146
    • 75649087741 scopus 로고    scopus 로고
    • CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
    • C.R. Stewart, L.M. Stuart, K. Wilkinson, J.M. van Gils, J. Deng, and A. Halle CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer Nat Immunol 11 2010 155 161
    • (2010) Nat Immunol , vol.11 , pp. 155-161
    • Stewart, C.R.1    Stuart, L.M.2    Wilkinson, K.3    Van Gils, J.M.4    Deng, J.5    Halle, A.6
  • 147
    • 58849083367 scopus 로고    scopus 로고
    • Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome
    • D.P. Stirling, S. Liu, P. Kubes, and V.W. Yong Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome J Neurosci 29 2009 753 764
    • (2009) J Neurosci , vol.29 , pp. 753-764
    • Stirling, D.P.1    Liu, S.2    Kubes, P.3    Yong, V.W.4
  • 150
    • 33748751857 scopus 로고    scopus 로고
    • Essential role of neutrophils in anti-type II collagen antibody and lipopolysaccharide-induced arthritis
    • DOI 10.1111/j.1365-2567.2006.02424.x
    • D. Tanaka, T. Kagari, H. Doi, and T. Shimozato Essential role of neutrophils in anti-type II collagen antibody and lipopolysaccharide-induced arthritis Immunology 119 2006 195 202 (Pubitemid 44401638)
    • (2006) Immunology , vol.119 , Issue.2 , pp. 195-202
    • Tanaka, D.1    Kagari, T.2    Doi, H.3    Shimozato, T.4
  • 152
    • 58149398634 scopus 로고    scopus 로고
    • CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis
    • L.A. Truman, C.A. Ford, M. Pasikowska, J.D. Pound, S.J. Wilkinson, and I.E. Dumitriu CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis Blood 112 2008 5026 5036
    • (2008) Blood , vol.112 , pp. 5026-5036
    • Truman, L.A.1    Ford, C.A.2    Pasikowska, M.3    Pound, J.D.4    Wilkinson, S.J.5    Dumitriu, I.E.6
  • 153
    • 77955356159 scopus 로고    scopus 로고
    • Cytokine overproduction, T-cell activation, and defective T-regulatory functions promote nephritis in systemic lupus erythematosus
    • M. Tucci, S. Stucci, S. Strippoli, and F. Silvestris Cytokine overproduction, T-cell activation, and defective T-regulatory functions promote nephritis in systemic lupus erythematosus J Biomed Biotechnol 2010 2010 457146
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 457146
    • Tucci, M.1    Stucci, S.2    Strippoli, S.3    Silvestris, F.4
  • 154
    • 77954983149 scopus 로고    scopus 로고
    • Tumor-initiating and -propagating cells: Cells that we would like to identify and control
    • B.B. Tysnes Tumor-initiating and -propagating cells: cells that we would like to identify and control Neoplasia 12 2010 506 515
    • (2010) Neoplasia , vol.12 , pp. 506-515
    • Tysnes, B.B.1
  • 156
    • 78751662679 scopus 로고    scopus 로고
    • Type 1 diabetes: Etiology, immunology, and therapeutic strategies
    • T.L. van Belle, K.T. Coppieters, and M.G. von Herrath Type 1 diabetes: etiology, immunology, and therapeutic strategies Physiol Rev 91 2011 79 118
    • (2011) Physiol Rev , vol.91 , pp. 79-118
    • Van Belle, T.L.1    Coppieters, K.T.2    Von Herrath, M.G.3
  • 157
    • 77956584113 scopus 로고    scopus 로고
    • Gout: Epitome of painful arthritis
    • T.B. VanItallie Gout: epitome of painful arthritis Metabolism 59 Suppl. 1 2010 S32 S36
    • (2010) Metabolism , vol.59 , Issue.SUPPL. 1
    • Vanitallie, T.B.1
  • 158
    • 57149104401 scopus 로고    scopus 로고
    • Postinjury immune monitoring: Can multiple organ failure be predicted?
    • T. Visser, J. Pillay, L. Koenderman, and L.P. Leenen Postinjury immune monitoring: can multiple organ failure be predicted? Curr Opin Crit Care 14 2008 666 672
    • (2008) Curr Opin Crit Care , vol.14 , pp. 666-672
    • Visser, T.1    Pillay, J.2    Koenderman, L.3    Leenen, L.P.4
  • 161
    • 77952426002 scopus 로고    scopus 로고
    • Fatigue in multiple sclerosis: Mechanisms and management
    • S. Vucic, D. Burke, and M.C. Kiernan Fatigue in multiple sclerosis: mechanisms and management Clin Neurophysiol 121 2010 809 817
    • (2010) Clin Neurophysiol , vol.121 , pp. 809-817
    • Vucic, S.1    Burke, D.2    Kiernan, M.C.3
  • 162
    • 60649102339 scopus 로고    scopus 로고
    • Pulmonary fibrosis: Pathogenesis, etiology and regulation
    • M.S. Wilson, and T.A. Wynn Pulmonary fibrosis: pathogenesis, etiology and regulation Mucosal Immunol 2 2009 103 121
    • (2009) Mucosal Immunol , vol.2 , pp. 103-121
    • Wilson, M.S.1    Wynn, T.A.2
  • 165
    • 77951690581 scopus 로고    scopus 로고
    • Molecular regulators of leucocyte chemotaxis during inflammation
    • C.H. Wong, B. Heit, and P. Kubes Molecular regulators of leucocyte chemotaxis during inflammation Cardiovasc Res 86 2010 183 191
    • (2010) Cardiovasc Res , vol.86 , pp. 183-191
    • Wong, C.H.1    Heit, B.2    Kubes, P.3
  • 166
    • 24944538819 scopus 로고    scopus 로고
    • VISA is an adapter protein required for virus-triggered IFN-β signaling
    • DOI 10.1016/j.molcel.2005.08.014, PII S109727650501556X
    • L.G. Xu, Y.Y. Wang, K.J. Han, L.Y. Li, Z. Zhai, and H.B. Shu VISA is an adapter protein required for virus-triggered IFN-beta signaling Mol Cell 19 2005 727 740 (Pubitemid 41316668)
    • (2005) Molecular Cell , vol.19 , Issue.6 , pp. 727-740
    • Xu, L.-G.1    Wang, Y.-Y.2    Han, K.-J.3    Li, L.-Y.4    Zhai, Z.5    Shu, H.-B.6
  • 168
    • 52549125928 scopus 로고    scopus 로고
    • Mincle is an ITAM-coupled activating receptor that senses damaged cells
    • S. Yamasaki, E. Ishikawa, M. Sakuma, H. Hara, K. Ogata, and T. Saito Mincle is an ITAM-coupled activating receptor that senses damaged cells Nat Immunol 9 2008 1179 1188
    • (2008) Nat Immunol , vol.9 , pp. 1179-1188
    • Yamasaki, S.1    Ishikawa, E.2    Sakuma, M.3    Hara, H.4    Ogata, K.5    Saito, T.6
  • 169
    • 70449092388 scopus 로고    scopus 로고
    • HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses
    • H. Yanai, T. Ban, Z. Wang, M.K. Choi, T. Kawamura, and H. Negishi HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses Nature 462 2009 99 103
    • (2009) Nature , vol.462 , pp. 99-103
    • Yanai, H.1    Ban, T.2    Wang, Z.3    Choi, M.K.4    Kawamura, T.5    Negishi, H.6
  • 170
    • 77952566304 scopus 로고    scopus 로고
    • The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type i interferon via a beta-catenin-dependent pathway
    • P. Yang, H. An, X. Liu, M. Wen, Y. Zheng, and Y. Rui The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway Nat Immunol 11 2010 487 494
    • (2010) Nat Immunol , vol.11 , pp. 487-494
    • Yang, P.1    An, H.2    Liu, X.3    Wen, M.4    Zheng, Y.5    Rui, Y.6
  • 173
    • 12344290452 scopus 로고    scopus 로고
    • Lethal anemia caused by interferon-β produced in mouse embryos carrying undigested DNA
    • DOI 10.1038/ni1146
    • H. Yoshida, Y. Okabe, K. Kawane, H. Fukuyama, and S. Nagata Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA Nat Immunol 6 2005 49 56 (Pubitemid 40136695)
    • (2005) Nature Immunology , vol.6 , Issue.1 , pp. 49-56
    • Yoshida, H.1    Okabe, Y.2    Kawane, K.3    Fukuyama, H.4    Nagata, S.5
  • 174
    • 0034468768 scopus 로고    scopus 로고
    • The role of neutrophils and inflammation in gastric mucosal injury
    • T. Yoshikawa, and Y. Naito The role of neutrophils and inflammation in gastric mucosal injury Free Radic Res 33 2000 785 794 (Pubitemid 32208486)
    • (2000) Free Radical Research , vol.33 , Issue.6 , pp. 785-794
    • Yoshikawa, T.1    Naito, Y.2
  • 175
    • 77950275298 scopus 로고    scopus 로고
    • Circulating mitochondrial DAMPs cause inflammatory responses to injury
    • Q. Zhang, M. Raoof, Y. Chen, Y. Sumi, T. Sursal, and W. Junger Circulating mitochondrial DAMPs cause inflammatory responses to injury Nature 464 2010 104 107
    • (2010) Nature , vol.464 , pp. 104-107
    • Zhang, Q.1    Raoof, M.2    Chen, Y.3    Sumi, Y.4    Sursal, T.5    Junger, W.6
  • 176
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • R. Zhou, A.S. Yazdi, P. Menu, and J. Tschopp A role for mitochondria in NLRP3 inflammasome activation Nature 469 2011 221 225
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 177
    • 78751637122 scopus 로고    scopus 로고
    • Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
    • R. Zust, L. Cervantes-Barragan, M. Habjan, R. Maier, B.W. Neuman, and J. Ziebuhr Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5 Nat Immunol 12 2011 137 143
    • (2011) Nat Immunol , vol.12 , pp. 137-143
    • Zust, R.1    Cervantes-Barragan, L.2    Habjan, M.3    Maier, R.4    Neuman, B.W.5    Ziebuhr, J.6


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