Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9

Journal of Clinical Investigation

Volumn 115, Issue 2, 2005, Pages 407-417

  Means, Terry K ^a   Latz, Eicke ^b   Hayashi, Fumitaka ^a   Murali, Mandakolathur R ^a   Golenbock, Douglas T ^b   Luster, Andrew D ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CD32 ANTIGEN; CHEMOKINE; CYTOKINE; DNA; NUCLEOPROTEIN; TOLL LIKE RECEPTOR 9; ANTINUCLEAR ANTIBODY; CELL SURFACE RECEPTOR; FC RECEPTOR; MEMBRANE PROTEIN; TLR9 PROTEIN, HUMAN; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANTIBODY DETECTION; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE COMPLEX DISEASE; INTRACELLULAR TRANSPORT; LYSOSOME; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; RHEUMATIC DISEASE; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; ANTIGEN ANTIBODY COMPLEX; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PATHOLOGY; PROTEIN BINDING;

ANTIBODIES, ANTINUCLEAR; ANTIGEN-ANTIBODY COMPLEX; DENDRITIC CELLS; HUMANS; IMMUNITY, NATURAL; LUPUS ERYTHEMATOSUS, SYSTEMIC; MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECEPTORS, IGG; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS;

EID: 85047693371     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI23025     Document Type: Article

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