P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1

Journal of Immunology

Volumn 182, Issue 8, 2009, Pages 5052-5062

  Qu, Yan ^a   Ramachandra, Lakshmi ^a   Mohr, Susanne ^a   Franchi, Luigi ^b   Harding, Clifford V ^a   Nunez, Gabriel ^b   Dubyak, George R ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING A CASPASE RECRUITMENT DOMAIN; CASPASE INHIBITOR; CELL PROTEIN; CRYOPYRIN; INTERLEUKIN 1BETA CONVERTING ENZYME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PURINERGIC P2X7 RECEPTOR; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; UNCLASSIFIED DRUG; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; CYTOSKELETON PROTEIN; HLA ANTIGEN CLASS 2; PURINERGIC P2 RECEPTOR; PYCARD PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOGENESIS; CELL MATURATION; CELL MEMBRANE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVATION; EXOCYTOSIS; EXOSOME; KNOCKOUT GENE; MACROPHAGE; MEMBRANE VESICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECT; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; SECRETION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CARRIER PROTEINS; CASPASE 1; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DENDRITIC CELLS; EXOSOMES; HISTOCOMPATIBILITY ANTIGENS CLASS II; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, PURINERGIC P2;

EID: 65249164404     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802968     Document Type: Article

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