Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

Nature

Volumn 416, Issue 6881, 2002, Pages 603-607

  Leadbetter, Elizabeth A ^a   Rifkin, Ian R ^a   Hohlbaum, Adreas M ^a   Beaudette, Britte C ^a   Shlomchik, Mark J ^b   Marshak Rothstein, Ann ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGENS; CELLS; IMMUNOLOGY; TISSUE;

IMMUNE SYSTEMS;

PATHOLOGY;

AUTOANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN M; LYMPHOCYTE ANTIGEN RECEPTOR; RHEUMATOID FACTOR; TOLL LIKE RECEPTOR;

MEDICINE;

ANIMAL CELL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE ACTIVATION; CHROMATIN; CONTROLLED STUDY; HOMEOSTASIS; IMMUNE SYSTEM; LYMPHOID TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN NUCLEIC ACID INTERACTION; TARGET CELL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, DIFFERENTIATION; B-LYMPHOCYTES; CHROMATIN; DEOXYRIBONUCLEASE I; DNA-BINDING PROTEINS; DROSOPHILA PROTEINS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, CELL SURFACE; RECEPTORS, COMPLEMENT 3B; RECEPTORS, COMPLEMENT 3D; RECEPTORS, IMMUNOLOGIC; RHEUMATOID FACTOR; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS;

ANIMALIA;

EID: 0037061453     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/416603a     Document Type: Article

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