Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

Nature

Volumn 434, Issue 7036, 2005, Pages 1035-1040

  Honda, Kenya ^a   Ohba, Yusuke ^a,b   Yanai, Hideyuki ^a   Hegishi, Hideo ^a   Mizutani, Tatsuaki ^a   Takaoka, Akinori ^a   Taya, Choji ^c   Taniguchi, Tadatsugu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; IMMUNOLOGY; LIPIDS; POSITIVE IONS;

DENDRITIC CELLS; ENDOSOMAL RETENTION; INTERFERON INDUCTION; TOLL-LIKE RECEPTOR 9 (TLR9);

CELLS;

ALPHA INTERFERON; BETA INTERFERON; CELL SURFACE RECEPTOR; DIFFERENTIATION ANTIGEN; DNA BINDING PROTEIN; IMMUNOGLOBULIN RECEPTOR; INTERFERON; INTERFERON REGULATORY FACTOR 7; IRF7 PROTEIN, MOUSE; MYD88 PROTEIN, MOUSE; MYELOID DIFFERENTIATION FACTOR 88; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TLR9 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 9;

BIOCHEMISTRY; BIOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DENDRITIC CELL; ENDOSOME; GENE ACTIVATION; GENETIC TRANSCRIPTION; LYSOSOME; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPATIAL DISCRIMINATION; TIME PERCEPTION; ANIMAL; BONE MARROW CELL; CELL LINE; CLASSIFICATION; CPG ISLAND; CYTOLOGY; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; TIME; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; BIOLOGICAL TRANSPORT; BONE MARROW CELLS; CELL LINE; CPG ISLANDS; DENDRITIC CELLS; DNA-BINDING PROTEINS; ENDOSOMES; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; MACROPHAGES; MICE; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TIME FACTORS; TOLL-LIKE RECEPTOR 9;

EID: 17844380477     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03547     Document Type: Article

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