메뉴 건너뛰기




Volumn 23, Issue 3-4, 2006, Pages 232-240

Molecular mechanisms of alcoholic pancreatitis

Author keywords

Alcohol; Alcoholic pancreatitis; Autodigestion; Pancreatic fibrosis

Indexed keywords

ALCOHOL; CYTOCHROME P450 2E1;

EID: 33644654915     PISSN: 02572753     EISSN: None     Source Type: Journal    
DOI: 10.1159/000090170     Document Type: Article
Times cited : (64)

References (88)
  • 1
    • 0021799908 scopus 로고
    • The natural history of alcoholic pancreatitis: Update 1985
    • Dreiling DA, Koller M: The natural history of alcoholic pancreatitis: update 1985. Mt Sinai J Med 1985;52:340-342.
    • (1985) Mt Sinai J Med , vol.52 , pp. 340-342
    • Dreiling, D.A.1    Koller, M.2
  • 3
    • 0018238473 scopus 로고
    • Multicenter survey of the etiology of pancreatic diseases. Relationship between the relative risk of developing chronic pancreatitis and alcohol, protein and lipid composition
    • Durbec JP, Sarles H: Multicenter survey of the etiology of pancreatic diseases. Relationship between the relative risk of developing chronic pancreatitis and alcohol, protein and lipid composition. Digestion 1978;18:337-350.
    • (1978) Digestion , vol.18 , pp. 337-350
    • Durbec, J.P.1    Sarles, H.2
  • 4
    • 0025950574 scopus 로고
    • Is tobacco a risk factor for chronic pancreatitis and alcoholic cirrhosis?
    • Bourliere M, Barthet M, Berthezene P, Durbec JP, Sarles H: Is tobacco a risk factor for chronic pancreatitis and alcoholic cirrhosis? Gut 1991;32:1392-1395.
    • (1991) Gut , vol.32 , pp. 1392-1395
    • Bourliere, M.1    Barthet, M.2    Berthezene, P.3    Durbec, J.P.4    Sarles, H.5
  • 6
    • 0021924848 scopus 로고
    • Diet and drinking habits in relation to the development of alcoholic pancreatitis
    • Wilson JS, Bernstein L, McDonald C, Tait A, McNeil D, Pirola RC: Diet and drinking habits in relation to the development of alcoholic pancreatitis. Gut 1985;26:882-887.
    • (1985) Gut , vol.26 , pp. 882-887
    • Wilson, J.S.1    Bernstein, L.2    McDonald, C.3    Tait, A.4    McNeil, D.5    Pirola, R.C.6
  • 8
    • 0028118380 scopus 로고
    • Lipid intolerance does not account for susceptibility to alcoholic and gallstone pancreatitis
    • Haber PS, Wilson JS, Apte MV, Hall W, Goumas K, Pirola RC: Lipid intolerance does not account for susceptibility to alcoholic and gallstone pancreatitis. Gastroenterology 1994;106:742-748.
    • (1994) Gastroenterology , vol.106 , pp. 742-748
    • Haber, P.S.1    Wilson, J.S.2    Apte, M.V.3    Hall, W.4    Goumas, K.5    Pirola, R.C.6
  • 12
    • 0020692534 scopus 로고
    • Effect of ethanol on sphincter of Oddi: An endoscopic manometric study
    • Viceconte G: Effect of ethanol on sphincter of Oddi: an endoscopic manometric study. Gut 1983;24:20-27.
    • (1983) Gut , vol.24 , pp. 20-27
    • Viceconte, G.1
  • 13
    • 0027161645 scopus 로고
    • The effect of alcohol in the pancreatic duct sphincter of Oddi
    • Goff JS: The effect of alcohol in the pancreatic duct sphincter of Oddi. Am J Gastroenterol 1993;88:656-660.
    • (1993) Am J Gastroenterol , vol.88 , pp. 656-660
    • Goff, J.S.1
  • 14
    • 0014743534 scopus 로고
    • Effects of intravenous alcohol on motility of the duodenum and the sphincter of Oddi
    • Pirola RC, Davis AE: Effects of intravenous alcohol on motility of the duodenum and the sphincter of Oddi. Aust Ann Med 1970;19:24-29.
    • (1970) Aust Ann Med , vol.19 , pp. 24-29
    • Pirola, R.C.1    Davis, A.E.2
  • 15
  • 16
    • 33644829194 scopus 로고    scopus 로고
    • Acute intravenous ethanol reduces sphincter of Oddi function in the Australian possum
    • Sonoda Y, Teng ME, Toouli J, Saccone GTP: Acute intravenous ethanol reduces sphincter of Oddi function in the Australian possum. Pancreas 2004;29:328.
    • (2004) Pancreas , vol.29 , pp. 328
    • Sonoda, Y.1    Teng, M.E.2    Toouli, J.3    Saccone, G.T.P.4
  • 17
    • 0027396742 scopus 로고
    • Pancreatic secretion in chronic alcoholics. Effects of acute alcohol or wine on response to a meal
    • Hajnal F, Carmen Flores M, Valenzuela JE: Pancreatic secretion in chronic alcoholics. Effects of acute alcohol or wine on response to a meal. Dig Dis Sci 1993;38:12-17.
    • (1993) Dig Dis Sci , vol.38 , pp. 12-17
    • Hajnal, F.1    Carmen Flores, M.2    Valenzuela, J.E.3
  • 18
    • 0015003781 scopus 로고
    • Alcoholism and pancreatitis
    • Sarles H: Alcoholism and pancreatitis. Scand J Gastroenterol 1971;6:193-198.
    • (1971) Scand J Gastroenterol , vol.6 , pp. 193-198
    • Sarles, H.1
  • 19
    • 0016162414 scopus 로고
    • Chronic calcifying pancreatitis - Chronic alcoholic pancreatitis
    • Sarles H: Chronic calcifying pancreatitis - chronic alcoholic pancreatitis. Gastroenterology 1974;66:604-616.
    • (1974) Gastroenterology , vol.66 , pp. 604-616
    • Sarles, H.1
  • 20
    • 0013840944 scopus 로고
    • Observations on 205 confirmed cases of acute pancreatitis, recurring pancreatitis, and chronic pancreatitis
    • Sarles H, Sarles JC, Camatte R, Muratore R, Gaini M, Guien C, Pastor J, Le Roy F: Observations on 205 confirmed cases of acute pancreatitis, recurring pancreatitis, and chronic pancreatitis. Gut 1965;6:545-559.
    • (1965) Gut , vol.6 , pp. 545-559
    • Sarles, H.1    Sarles, J.C.2    Camatte, R.3    Muratore, R.4    Gaini, M.5    Guien, C.6    Pastor, J.7    Le Roy, F.8
  • 26
    • 0027269850 scopus 로고
    • Induction of drug-metabolizing enzymes in human pancreatic cancer and chronic pancreatitis
    • Foster JR, Idle JR, Hardwick JP, Bars R, Scott P, Braganza JM: Induction of drug-metabolizing enzymes in human pancreatic cancer and chronic pancreatitis. J Pathol 1993;169:457-463.
    • (1993) J Pathol , vol.169 , pp. 457-463
    • Foster, J.R.1    Idle, J.R.2    Hardwick, J.P.3    Bars, R.4    Scott, P.5    Braganza, J.M.6
  • 27
    • 0023900010 scopus 로고
    • Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: Regulation and characteristics of enzymes belonging to the iib and iie gene subfamilies
    • Johansson I, Ekstrom G, Scholte B, Puzycki D, Jornvall H, Ingelman-Sundberg M: Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the iib and iie gene subfamilies. Biochemistry 1988;27:1925-1934.
    • (1988) Biochemistry , vol.27 , pp. 1925-1934
    • Johansson, I.1    Ekstrom, G.2    Scholte, B.3    Puzycki, D.4    Jornvall, H.5    Ingelman-Sundberg, M.6
  • 28
    • 0022634648 scopus 로고
    • Presence of nonoxidative ethanol metabolism in human organs commonly damaged by ethanol abuse
    • Laposata EA, Lange LG: Presence of nonoxidative ethanol metabolism in human organs commonly damaged by ethanol abuse. Science 1986;231:497-499.
    • (1986) Science , vol.231 , pp. 497-499
    • Laposata, E.A.1    Lange, L.G.2
  • 29
    • 0025014704 scopus 로고
    • Nonoxidative metabolism of ethanol in the pancreas; implication in alcoholic pancreatic damage
    • Hamamoto T, Yamada S, Hirayama C: Nonoxidative metabolism of ethanol in the pancreas; implication in alcoholic pancreatic damage. Biochem Pharmacol 1990;39:241-245.
    • (1990) Biochem Pharmacol , vol.39 , pp. 241-245
    • Hamamoto, T.1    Yamada, S.2    Hirayama, C.3
  • 30
    • 0035002111 scopus 로고    scopus 로고
    • Linkage of oxidative and nonoxidative ethanol metabolism in the pancreas and toxicity of nonoxidative ethanol metabolites for pancreatic acinar cells
    • Werner J, Saghir M, Fernandez-del Castillo C, Warshaw AL, Laposata M: Linkage of oxidative and nonoxidative ethanol metabolism in the pancreas and toxicity of nonoxidative ethanol metabolites for pancreatic acinar cells. Surgery 2001;129:736-744.
    • (2001) Surgery , vol.129 , pp. 736-744
    • Werner, J.1    Saghir, M.2    Fernandez-del Castillo, C.3    Warshaw, A.L.4    Laposata, M.5
  • 31
    • 0027994257 scopus 로고
    • The synthesis of fatty acid ethyl ester by carboxylester lipase
    • Tsujita T, Okuda H: The synthesis of fatty acid ethyl ester by carboxylester lipase. Eur J Biochem 1994;224:57-62.
    • (1994) Eur J Biochem , vol.224 , pp. 57-62
    • Tsujita, T.1    Okuda, H.2
  • 32
    • 0027278594 scopus 로고
    • Fatty acid ethyl esters increase rat pancreatic lysosomal fragility
    • Haber PS, Wilson JS, Apte MV, Pirola RC: Fatty acid ethyl esters increase rat pancreatic lysosomal fragility. J Lab Clin Med 1993;121:759-764.
    • (1993) J Lab Clin Med , vol.121 , pp. 759-764
    • Haber, P.S.1    Wilson, J.S.2    Apte, M.V.3    Pirola, R.C.4
  • 34
    • 0023819094 scopus 로고
    • Potentiation of ethanol-induced pancreatic injury by dietary fat. Induction of chronic pancreatitis by alcohol in rats
    • Tsukamoto H, Towner SJ, Yu GS, French SW: Potentiation of ethanol-induced pancreatic injury by dietary fat. Induction of chronic pancreatitis by alcohol in rats. Am J Pathol 1988;131:246-257.
    • (1988) Am J Pathol , vol.131 , pp. 246-257
    • Tsukamoto, H.1    Towner, S.J.2    Yu, G.S.3    French, S.W.4
  • 35
  • 36
    • 0030920325 scopus 로고    scopus 로고
    • The drinker's pancreas: Molecular mechanisms emerge
    • Wilson JS, Pirola RC: The drinker's pancreas: molecular mechanisms emerge. Gastroenterology 1997;113:355-358.
    • (1997) Gastroenterology , vol.113 , pp. 355-358
    • Wilson, J.S.1    Pirola, R.C.2
  • 37
    • 3042720190 scopus 로고    scopus 로고
    • Chronic alcohol-induced alterations in the pancreatic secretory control mechanisms
    • Deng X, Wood PG, Eagon PK, Whitcomb DC: Chronic alcohol-induced alterations in the pancreatic secretory control mechanisms. Dig Dis Sci 2004;49:805-819.
    • (2004) Dig Dis Sci , vol.49 , pp. 805-819
    • Deng, X.1    Wood, P.G.2    Eagon, P.K.3    Whitcomb, D.C.4
  • 38
    • 0023164370 scopus 로고
    • Effect of ethanol on amylase secretion and cellular calcium homeostasis in pancreatic acini from normal and ethanol-fed rats
    • Ponnappa BC, Hoek JB, Waring AJ, Rubin E: Effect of ethanol on amylase secretion and cellular calcium homeostasis in pancreatic acini from normal and ethanol-fed rats. Biochem Pharmacol 1987;36:69-79.
    • (1987) Biochem Pharmacol , vol.36 , pp. 69-79
    • Ponnappa, B.C.1    Hoek, J.B.2    Waring, A.J.3    Rubin, E.4
  • 39
    • 1842611506 scopus 로고    scopus 로고
    • Ethanol modifies the actin cytoskeleton in rat pancreatic acinar cells - Comparison with effects of CCK
    • Siegmund E, Luthen F, Kunert J, Weber H: Ethanol modifies the actin cytoskeleton in rat pancreatic acinar cells - comparison with effects of CCK. Pancreatology 2004;4:12-21.
    • (2004) Pancreatology , vol.4 , pp. 12-21
    • Siegmund, E.1    Luthen, F.2    Kunert, J.3    Weber, H.4
  • 40
    • 0242316721 scopus 로고
    • Premature activation of pancreatic zymogens and its role in the pathogeny of chronic calcifying pancreatitis
    • Figarella C, Amouric M, Guy-Crotte O: Premature activation of pancreatic zymogens and its role in the pathogeny of chronic calcifying pancreatitis. Dig Dis Sci 1984;29:948.
    • (1984) Dig Dis Sci , vol.29 , pp. 948
    • Figarella, C.1    Amouric, M.2    Guy-Crotte, O.3
  • 41
    • 7144257565 scopus 로고    scopus 로고
    • Inhibition of cathepsin b activity blocks caerulein induced in vitro activation of trypsinogen in rat pancreatic acini
    • Saluja A, Donovan E, Yamanaka K, Yamaguchi Y, Hofbauer B, Steer M: Inhibition of cathepsin b activity blocks caerulein induced in vitro activation of trypsinogen in rat pancreatic acini. Gastroenterology 1996;110:A428.
    • (1996) Gastroenterology , vol.110
    • Saluja, A.1    Donovan, E.2    Yamanaka, K.3    Yamaguchi, Y.4    Hofbauer, B.5    Steer, M.6
  • 43
    • 0029162726 scopus 로고
    • The effect of chronic alcohol administration on cerulein-induced pancreatitis
    • Korsten MA, Haber PS, Wilson JS, Lieber CS: The effect of chronic alcohol administration on cerulein-induced pancreatitis. Int J Pancreatol 1995;18:25-31.
    • (1995) Int J Pancreatol , vol.18 , pp. 25-31
    • Korsten, M.A.1    Haber, P.S.2    Wilson, J.S.3    Lieber, C.S.4
  • 45
    • 25444451078 scopus 로고    scopus 로고
    • A mouse model of ethanol dependent pancreatic fibrosis
    • Perides G, Tao X, West N, Sharma A, Steer ML: A mouse model of ethanol dependent pancreatic fibrosis. Gut 2005;54:1461-1467.
    • (2005) Gut , vol.54 , pp. 1461-1467
    • Perides, G.1    Tao, X.2    West, N.3    Sharma, A.4    Steer, M.L.5
  • 46
    • 21644434563 scopus 로고    scopus 로고
    • Ethanol consumption potentiates viral pancreatitis and may inhibit pancreas regeneration: Preliminary findings
    • Clemens DL, Jerrells TR: Ethanol consumption potentiates viral pancreatitis and may inhibit pancreas regeneration: preliminary findings. Alcohol 2004;33:183-189.
    • (2004) Alcohol , vol.33 , pp. 183-189
    • Clemens, D.L.1    Jerrells, T.R.2
  • 50
    • 0026343189 scopus 로고
    • The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis
    • Nordback IH, MacGowan S, Potter JJ, Cameron JL: The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis. Ann Surg 1991;214:671-678.
    • (1991) Ann Surg , vol.214 , pp. 671-678
    • Nordback, I.H.1    MacGowan, S.2    Potter, J.J.3    Cameron, J.L.4
  • 52
    • 84990613868 scopus 로고
    • Metabolism of ethanol and associated hepatotoxicity
    • Lieber CS: Metabolism of ethanol and associated hepatotoxicity. Drug Alcohol Rev 1991;10:175-202.
    • (1991) Drug Alcohol Rev , vol.10 , pp. 175-202
    • Lieber, C.S.1
  • 53
    • 0029902753 scopus 로고    scopus 로고
    • Acute ethanol administration induces oxidative changes in rat pancreatic tissue
    • Altomare E, Grattagliano I, Vendemiale G, Palmieri V, Palasciano G: Acute ethanol administration induces oxidative changes in rat pancreatic tissue. Gut 1996;38:742-746.
    • (1996) Gut , vol.38 , pp. 742-746
    • Altomare, E.1    Grattagliano, I.2    Vendemiale, G.3    Palmieri, V.4    Palasciano, G.5
  • 56
    • 0033828142 scopus 로고    scopus 로고
    • Collagen type I synthesized by pancreatic periacinar stellate cells (PSC) co-localizes with lipid peroxidation-derived aldehydes in chronic alcoholic pancreatitis
    • Casini A, Galli A, Pignalosa P, Frulloni L, Grappone C, Milani S, Pederzoli P, Cavallini G, Surrenti C: Collagen type I synthesized by pancreatic periacinar stellate cells (PSC) co-localizes with lipid peroxidation-derived aldehydes in chronic alcoholic pancreatitis. J Pathol 2000;192:81-89.
    • (2000) J Pathol , vol.192 , pp. 81-89
    • Casini, A.1    Galli, A.2    Pignalosa, P.3    Frulloni, L.4    Grappone, C.5    Milani, S.6    Pederzoli, P.7    Cavallini, G.8    Surrenti, C.9
  • 57
    • 0019511768 scopus 로고
    • Ethanol-induced lipid peroxidation: Potentiation by long-term alcohol feeding and attenuation by methionine
    • Shaw S, Jayatilleke E, Ross WA, Gordon ER, Leiber CS: Ethanol-induced lipid peroxidation: potentiation by long-term alcohol feeding and attenuation by methionine. J Lab Clin Med 1981;98:417-424.
    • (1981) J Lab Clin Med , vol.98 , pp. 417-424
    • Shaw, S.1    Jayatilleke, E.2    Ross, W.A.3    Gordon, E.R.4    Leiber, C.S.5
  • 58
    • 0026519850 scopus 로고
    • The role of cellular oxidases and catalytic iron in the pathogenesis of ethanol-induced liver injury
    • Shaw S, Jayatilleke E: The role of cellular oxidases and catalytic iron in the pathogenesis of ethanol-induced liver injury. Life Sci 1992;50:2045-2052.
    • (1992) Life Sci , vol.50 , pp. 2045-2052
    • Shaw, S.1    Jayatilleke, E.2
  • 59
    • 0024546914 scopus 로고
    • Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1)
    • Ekstrom G, Ingelman-Sundberg M: Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1). Biochem Pharmacol 1989;38:1313-1319.
    • (1989) Biochem Pharmacol , vol.38 , pp. 1313-1319
    • Ekstrom, G.1    Ingelman-Sundberg, M.2
  • 61
    • 0023910790 scopus 로고
    • Formation of fatty acid ethyl esters during chronic ethanol treatment in mice
    • Hungund BL, Goldstein DB, Villegas F, Cooper TB: Formation of fatty acid ethyl esters during chronic ethanol treatment in mice. Biochem Pharmacol 1988;37:3001-3004.
    • (1988) Biochem Pharmacol , vol.37 , pp. 3001-3004
    • Hungund, B.L.1    Goldstein, D.B.2    Villegas, F.3    Cooper, T.B.4
  • 62
    • 0020573718 scopus 로고
    • Mitochondrial dysfunction induced by fatty acid ethyl esters, myocardial metabolites of ethanol
    • Lange LG, Sobel BE: Mitochondrial dysfunction induced by fatty acid ethyl esters, myocardial metabolites of ethanol. J Clin Invest 1983;72:724-731.
    • (1983) J Clin Invest , vol.72 , pp. 724-731
    • Lange, L.G.1    Sobel, B.E.2
  • 63
    • 0020062584 scopus 로고
    • Alcohol causes a fatty pancreas. A rat model of ethanol-induced pancreatic steatosis
    • Wilson JS, Colley PW, Sosula L, Pirola RC: Alcohol causes a fatty pancreas. A rat model of ethanol-induced pancreatic steatosis. Alcohol Clin Exp Res 1982;6:117-121.
    • (1982) Alcohol Clin Exp Res , vol.6 , pp. 117-121
    • Wilson, J.S.1    Colley, P.W.2    Sosula, L.3    Pirola, R.C.4
  • 64
    • 0028905980 scopus 로고
    • Development of chronic pancreatitis from acute pancreatitis: A pathogenetic concept
    • Kloppel G, Maillet B: Development of chronic pancreatitis from acute pancreatitis: a pathogenetic concept. Zentralbl Chir 1995;120:274-277.
    • (1995) Zentralbl Chir , vol.120 , pp. 274-277
    • Kloppel, G.1    Maillet, B.2
  • 65
    • 0347810078 scopus 로고
    • The etiology of pancreatitis. A review of clinical experience
    • Howard JM, Ehrlich EW: The etiology of pancreatitis. A review of clinical experience. Ann Surg 1960;152:135-137.
    • (1960) Ann Surg , vol.152 , pp. 135-137
    • Howard, J.M.1    Ehrlich, E.W.2
  • 68
    • 0028295094 scopus 로고
    • Progression of alcoholic acute to chronic pancreatitis
    • Ammann RW, Muellhaupt B: Progression of alcoholic acute to chronic pancreatitis. Gut 1994;35:552-556.
    • (1994) Gut , vol.35 , pp. 552-556
    • Ammann, R.W.1    Muellhaupt, B.2
  • 70
    • 0035163355 scopus 로고    scopus 로고
    • Study on free radicals and pancreatic fibrosis - Pancreatic fibrosis induced by repeated injections of superoxide dismutase inhibitor
    • Matsumura N, Ochi K, Ichimura M, Mizushima T, Harada H, Harada M: Study on free radicals and pancreatic fibrosis - pancreatic fibrosis induced by repeated injections of superoxide dismutase inhibitor. Pancreas 2001;22:53-57.
    • (2001) Pancreas , vol.22 , pp. 53-57
    • Matsumura, N.1    Ochi, K.2    Ichimura, M.3    Mizushima, T.4    Harada, H.5    Harada, M.6
  • 73
    • 0020415180 scopus 로고
    • Morphological studies on a vitamin a-storing cell and its complex with macrophage observed in mouse pancreatic tissues following excess vitamin a administration
    • Watari N, Hotta Y, Mabuchi Y: Morphological studies on a vitamin a-storing cell and its complex with macrophage observed in mouse pancreatic tissues following excess vitamin a administration. Okajimas Folia Anat Jpn 1982;58:837-858.
    • (1982) Okajimas Folia Anat Jpn , vol.58 , pp. 837-858
    • Watari, N.1    Hotta, Y.2    Mabuchi, Y.3
  • 76
    • 33746521801 scopus 로고
    • The cellular basis of hepatic fibrosis
    • Friedman SD: The cellular basis of hepatic fibrosis. N Engl J Med 1993;328:1828-1835.
    • (1993) N Engl J Med , vol.328 , pp. 1828-1835
    • Friedman, S.D.1
  • 77
    • 16344384885 scopus 로고    scopus 로고
    • Mechanisms of pancreatic fibrosis
    • Apte MV, Wilson JS: Mechanisms of pancreatic fibrosis. Dig Dis 2004;22:273-279.
    • (2004) Dig Dis , vol.22 , pp. 273-279
    • Apte, M.V.1    Wilson, J.S.2
  • 79
    • 0242349254 scopus 로고    scopus 로고
    • Stellate cell activation in alcoholic pancreatitis
    • Apte MV, Wilson JS: Stellate cell activation in alcoholic pancreatitis. Pancreas 2003;27:316-320.
    • (2003) Pancreas , vol.27 , pp. 316-320
    • Apte, M.V.1    Wilson, J.S.2
  • 83
    • 0030296956 scopus 로고    scopus 로고
    • Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis
    • Reeves HL, Burt AD, Wood S, Day CP: Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis. J Hepatol 1996;25:677-683.
    • (1996) J Hepatol , vol.25 , pp. 677-683
    • Reeves, H.L.1    Burt, A.D.2    Wood, S.3    Day, C.P.4
  • 86
    • 0036082384 scopus 로고    scopus 로고
    • Alcohol activates activator protein-1 and mitogen-activated protein kinases in rat pancreatic stellate cells
    • Masamune A, Kikuta K, Satoh M, Satoh A, Shimosegawa T: Alcohol activates activator protein-1 and mitogen-activated protein kinases in rat pancreatic stellate cells. J Pharmacol Exp Ther 2002;302:36-42.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 36-42
    • Masamune, A.1    Kikuta, K.2    Satoh, M.3    Satoh, A.4    Shimosegawa, T.5
  • 88
    • 33644644861 scopus 로고    scopus 로고
    • Alcoholic pancreatic fibrosis: Role of the phosphatidylinositol-3 kinase (PI3-K) and protein kinase C (PKC) pathways in pancreatic stellate cells
    • McCarroll JA, Phillips P, Santucci N, Pirola RC, Wilson JS, Apte MV: Alcoholic pancreatic fibrosis: role of the phosphatidylinositol-3 kinase (PI3-K) and protein kinase C (PKC) pathways in pancreatic stellate cells. Pancreas 2004;29:347.
    • (2004) Pancreas , vol.29 , pp. 347
    • McCarroll, J.A.1    Phillips, P.2    Santucci, N.3    Pirola, R.C.4    Wilson, J.S.5    Apte, M.V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.