IRF-7 is the master regulator of type-I interferon-dependent immune responses

Nature

Volumn 434, Issue 7034, 2005, Pages 772-777

  Honda, Kenya ^a   Yanai, Hideyuki ^a   Negishi, Hideo ^a   Asagiri, Masataka ^a   Sato, Mitsuharu ^b   Mizutani, Tatsuaki ^a   Shimada, Naoya ^a   Ohba, Yusuke ^a,c   Takaoka, Akinori ^a   Yoshida, Nobuaki ^b   Taniguchi, Tadatsugu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GENES; MICROBIOLOGY; VIRUSES;

CYTOSOLIC DETECTION; DIFFERENTIATED PLASMACYTOID DENDRITIC CELLS; TOLL-LIKE RECEPTOR 9 (TLR9) SUBFAMILY; TRANSCRIPTION FACTOR IRF-7; TYPE-I INTERFERON (IFN-Α/Β) RESPONSE;

IMMUNOLOGY;

ADAPTOR PROTEIN; ALPHA INTERFERON; BETA INTERFERON; CD8 ANTIGEN; INTERFERON; INTERFERON REGULATORY FACTOR 7; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 9; CELL SURFACE RECEPTOR; DIFFERENTIATION ANTIGEN; DNA BINDING PROTEIN; FLT3 LIGAND PROTEIN; IMMUNOGLOBULIN RECEPTOR; IRF7 PROTEIN, MOUSE; MEMBRANE PROTEIN; MESSENGER RNA; MYD88 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TLR9 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BLOOD LEVEL; CD8+ T LYMPHOCYTE; CELL TYPE; CONTROLLED STUDY; CYTOSOL; DENDRITIC CELL; FIBROBLAST; GENE; GENE INDUCTION; IMMUNE RESPONSE; INTERFERON PRODUCTION; IRF7 GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; VIRUS IMMUNITY; VIRUS INFECTION; ANIMAL; CPG ISLAND; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOUSE MUTANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; CD8-POSITIVE T-LYMPHOCYTES; CPG ISLANDS; DENDRITIC CELLS; DNA-BINDING PROTEINS; FIBROBLASTS; GENE EXPRESSION REGULATION; IMMUNITY, NATURAL; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9; VIRUS DISEASES;

EID: 17144404177     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature03464     Document Type: Article

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