Why functional pre-erythrocytic and bloodstage malaria vaccines fail: A meta-analysis of fully protective immunizations and novel immunological model

PLoS ONE

Volumn 5, Issue 5, 2010, Pages

  Guilbride, D Lys ^a,c   Gawlinski, Pawel ^a   Guilbride, Patrick D L ^b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b ROYAL VETERINARY COLLEGE   (United Kingdom)

^c DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; CIRCUMSPOROZOITE PROTEIN; MALARIA VACCINE; PRIMAQUINE; THROMBOSPONDIN;

ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL TRIAL; DISEASE MODEL; DRUG EFFICACY; DRUG MEGADOSE; HOST PARASITE INTERACTION; HOST SUSCEPTIBILITY; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; INSECT BITE; MALARIA; MICROBIAL ACTIVITY; MULTIPLE CYCLE TREATMENT; NONHUMAN; PLASMODIUM; PLASMODIUM (LIFE CYCLE STAGE); REGULATORY T LYMPHOCYTE; REINFECTION; T LYMPHOCYTE ACTIVATION; VACCINE FAILURE; VACCINE PRODUCTION; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECT; ERYTHROCYTE; GROWTH, DEVELOPMENT AND AGING; IMMUNE EVASION; IMMUNIZATION; IMMUNOLOGY; LIFE CYCLE; META ANALYSIS; PARASITOLOGY; PATHOLOGY; SKIN; TIME;

ANIMALS; CHLOROQUINE; ERYTHROCYTES; HUMANS; IMMUNE EVASION; IMMUNE TOLERANCE; IMMUNIZATION; IMMUNOMODULATION; LIFE CYCLE STAGES; MALARIA; MALARIA VACCINES; MODELS, IMMUNOLOGICAL; PLASMODIUM; SKIN; T-LYMPHOCYTES, REGULATORY; TIME FACTORS;

EID: 77956282037     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010685     Document Type: Article

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