메뉴 건너뛰기




Volumn 27, Issue 8, 2009, Pages 1266-1271

Intranasal administration of the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei with the modified heat-labile toxin of Escherichia coli (LTK63) induces a complete protection against malaria challenge

Author keywords

LTK63; Parasitic protozoan; Rodent; T lymphocytes

Indexed keywords

CIRCUMSPOROZOITE PROTEIN; ESCHERICHIA COLI ENTEROTOXIN; MALARIA VACCINE;

EID: 58749088034     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.12.010     Document Type: Article
Times cited : (15)

References (35)
  • 1
    • 33846256606 scopus 로고    scopus 로고
    • A review of human vaccine research and development: malaria
    • Girard M.P., Reed Z.H., Friede M., and Kieny M.P. A review of human vaccine research and development: malaria. Vaccine 25 Feb 19 (9) (2007) 1567-1580
    • (2007) Vaccine , vol.25 , Issue.Feb 19 9 , pp. 1567-1580
    • Girard, M.P.1    Reed, Z.H.2    Friede, M.3    Kieny, M.P.4
  • 2
    • 4544258068 scopus 로고    scopus 로고
    • NALT- versus Peyer's-patch-mediated mucosal immunity
    • Kiyono H., and Fukuyama S. NALT- versus Peyer's-patch-mediated mucosal immunity. Nat Rev Immunol 4 Sep (9) (2004) 699-710
    • (2004) Nat Rev Immunol , vol.4 , Issue.Sep 9 , pp. 699-710
    • Kiyono, H.1    Fukuyama, S.2
  • 3
    • 0030740163 scopus 로고    scopus 로고
    • Nasal lymphoid tissue, intranasal immunization, and compartmentalization of the common mucosal immune system
    • Wu H.Y., and Russell M.W. Nasal lymphoid tissue, intranasal immunization, and compartmentalization of the common mucosal immune system. Immunol Res 16 2 (1997) 187-201
    • (1997) Immunol Res , vol.16 , Issue.2 , pp. 187-201
    • Wu, H.Y.1    Russell, M.W.2
  • 4
    • 33646346587 scopus 로고    scopus 로고
    • In vivo activation of naive CD4+ T cells in nasal mucosa-associated lymphoid tissue following intranasal immunization with recombinant Streptococcus gordonii
    • Medaglini D., Ciabattini A., Cuppone A.M., Costa C., Ricci S., Costalonga M., et al. In vivo activation of naive CD4+ T cells in nasal mucosa-associated lymphoid tissue following intranasal immunization with recombinant Streptococcus gordonii. Infect Immun 74 May (5) (2006) 2760-2766
    • (2006) Infect Immun , vol.74 , Issue.May 5 , pp. 2760-2766
    • Medaglini, D.1    Ciabattini, A.2    Cuppone, A.M.3    Costa, C.4    Ricci, S.5    Costalonga, M.6
  • 5
    • 3042681606 scopus 로고    scopus 로고
    • Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin
    • Bowe F., Lavelle E.C., McNeela E.A., Hale C., Clare S., Arico B., et al. Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin. Infect Immun 72 Jul (7) (2004) 4052-4060
    • (2004) Infect Immun , vol.72 , Issue.Jul 7 , pp. 4052-4060
    • Bowe, F.1    Lavelle, E.C.2    McNeela, E.A.3    Hale, C.4    Clare, S.5    Arico, B.6
  • 6
    • 0038281537 scopus 로고    scopus 로고
    • Nasal tolerance induces antigen-specific CD4+ CD25- regulatory T cells that can transfer their regulatory capacity to naive CD4+ T cells
    • Unger W.W., Jansen W., Wolvers D.A., van Halteren A.G., Kraal G., and Samsom J.N. Nasal tolerance induces antigen-specific CD4+ CD25- regulatory T cells that can transfer their regulatory capacity to naive CD4+ T cells. Int Immunol 15 Jun (6) (2003) 731-739
    • (2003) Int Immunol , vol.15 , Issue.Jun 6 , pp. 731-739
    • Unger, W.W.1    Jansen, W.2    Wolvers, D.A.3    van Halteren, A.G.4    Kraal, G.5    Samsom, J.N.6
  • 7
    • 0026458260 scopus 로고
    • Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
    • Spangler B.D. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol Rev 56 Dec (4) (1992) 622-647
    • (1992) Microbiol Rev , vol.56 , Issue.Dec 4 , pp. 622-647
    • Spangler, B.D.1
  • 8
    • 0021058990 scopus 로고
    • New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development
    • Levine M.M., Kaper J.B., Black R.E., and Clements M.L. New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol Rev 47 Dec (4) (1983) 510-550
    • (1983) Microbiol Rev , vol.47 , Issue.Dec 4 , pp. 510-550
    • Levine, M.M.1    Kaper, J.B.2    Black, R.E.3    Clements, M.L.4
  • 9
    • 0035925592 scopus 로고    scopus 로고
    • Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants
    • Pizza M., Giuliani M.M., Fontana M.R., Monaci E., Douce G., Dougan G., et al. Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants. Vaccine 19 Mar 21 (17-19) (2001) 2534-2541
    • (2001) Vaccine , vol.19 , Issue.Mar 21 17-19 , pp. 2534-2541
    • Pizza, M.1    Giuliani, M.M.2    Fontana, M.R.3    Monaci, E.4    Douce, G.5    Dougan, G.6
  • 10
    • 0032748077 scopus 로고    scopus 로고
    • Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins
    • Rappuoli R., Pizza M., Douce G., Dougan G., and Structure. Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins. Immunol Today 20 Nov (11) (1999) 493-500
    • (1999) Immunol Today , vol.20 , Issue.Nov 11 , pp. 493-500
    • Rappuoli, R.1    Pizza, M.2    Douce, G.3    Dougan, G.4    Structure5
  • 11
    • 0035863815 scopus 로고    scopus 로고
    • Mucosal delivery of a respiratory syncytial virus CTL peptide with enterotoxin-based adjuvants elicits protective, immunopathogenic, and immunoregulatory antiviral CD8+ T cell responses
    • Simmons C.P., Hussell T., Sparer T., Walzl G., Openshaw P., and Dougan G. Mucosal delivery of a respiratory syncytial virus CTL peptide with enterotoxin-based adjuvants elicits protective, immunopathogenic, and immunoregulatory antiviral CD8+ T cell responses. J Immunol 166 Jan 15 (2) (2001) 1106-1113
    • (2001) J Immunol , vol.166 , Issue.Jan 15 2 , pp. 1106-1113
    • Simmons, C.P.1    Hussell, T.2    Sparer, T.3    Walzl, G.4    Openshaw, P.5    Dougan, G.6
  • 12
    • 10344265511 scopus 로고    scopus 로고
    • Innate imprinting by the modified heat-labile toxin of Escherichia coli (LTK63) provides generic protection against lung infectious disease
    • Williams A.E., Edwards L., Humphreys I.R., Snelgrove R., Rae A., Rappuoli R., et al. Innate imprinting by the modified heat-labile toxin of Escherichia coli (LTK63) provides generic protection against lung infectious disease. J Immunol 173 Dec 15 (12) (2004) 7435-7443
    • (2004) J Immunol , vol.173 , Issue.Dec 15 12 , pp. 7435-7443
    • Williams, A.E.1    Edwards, L.2    Humphreys, I.R.3    Snelgrove, R.4    Rae, A.5    Rappuoli, R.6
  • 13
    • 0031986493 scopus 로고    scopus 로고
    • Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant
    • Marchetti M., Rossi M., Giannelli V., Giuliani M.M., Pizza M., Censini S., et al. Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant. Vaccine 16 Jan (1) (1998) 33-37
    • (1998) Vaccine , vol.16 , Issue.Jan 1 , pp. 33-37
    • Marchetti, M.1    Rossi, M.2    Giannelli, V.3    Giuliani, M.M.4    Pizza, M.5    Censini, S.6
  • 14
    • 0033797049 scopus 로고    scopus 로고
    • Genetically detoxified mutants of heat-labile enterotoxin from Escherichia coli are effective adjuvants for induction of cytotoxic T-cell responses against HIV-1 gag-p55
    • Neidleman J.A., Vajdy M., Ugozzoli M., Ott G., and O'Hagan D. Genetically detoxified mutants of heat-labile enterotoxin from Escherichia coli are effective adjuvants for induction of cytotoxic T-cell responses against HIV-1 gag-p55. Immunology 101 Sep (1) (2000) 154-160
    • (2000) Immunology , vol.101 , Issue.Sep 1 , pp. 154-160
    • Neidleman, J.A.1    Vajdy, M.2    Ugozzoli, M.3    Ott, G.4    O'Hagan, D.5
  • 15
    • 33646447036 scopus 로고    scopus 로고
    • Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers
    • Stephenson I., Zambon M.C., Rudin A., Colegate A., Podda A., Bugarini R., et al. Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers. J Virol 80 May (10) (2006) 4962-4970
    • (2006) J Virol , vol.80 , Issue.May 10 , pp. 4962-4970
    • Stephenson, I.1    Zambon, M.C.2    Rudin, A.3    Colegate, A.4    Podda, A.5    Bugarini, R.6
  • 16
    • 0031693715 scopus 로고    scopus 로고
    • Intranasal immunization with yeast-expressed 19 kD carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (yMSP119) induces protective immunity to blood stage malaria infection in mice
    • Hirunpetcharat C., Stanisic D., Liu X.Q., Vadolas J., Strugnell R.A., Lee R., et al. Intranasal immunization with yeast-expressed 19 kD carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (yMSP119) induces protective immunity to blood stage malaria infection in mice. Parasite Immunol 20 Sep (9) (1998) 413-420
    • (1998) Parasite Immunol , vol.20 , Issue.Sep 9 , pp. 413-420
    • Hirunpetcharat, C.1    Stanisic, D.2    Liu, X.Q.3    Vadolas, J.4    Strugnell, R.A.5    Lee, R.6
  • 17
    • 27744520417 scopus 로고    scopus 로고
    • Nasal immunization with a malaria transmission-blocking vaccine candidate, Pfs25, induces complete protective immunity in mice against field isolates of Plasmodium falciparum
    • Arakawa T., Komesu A., Otsuki H., Sattabongkot J., Udomsangpetch R., Matsumoto Y., et al. Nasal immunization with a malaria transmission-blocking vaccine candidate, Pfs25, induces complete protective immunity in mice against field isolates of Plasmodium falciparum. Infect Immun 73 Nov (11) (2005) 7375-7380
    • (2005) Infect Immun , vol.73 , Issue.Nov 11 , pp. 7375-7380
    • Arakawa, T.1    Komesu, A.2    Otsuki, H.3    Sattabongkot, J.4    Udomsangpetch, R.5    Matsumoto, Y.6
  • 18
    • 55049115986 scopus 로고    scopus 로고
    • New malaria vaccine candidates based on the Plasmodium vivax Merozoite Surface Protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin
    • Bargieri D.Y., Rosa D.S., Braga C.J., Carvalho B.O., Costa F.T., Espindola N.M., et al. New malaria vaccine candidates based on the Plasmodium vivax Merozoite Surface Protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin. Vaccine 26 Nov 11 (48) (2008) 6132-6142
    • (2008) Vaccine , vol.26 , Issue.Nov 11 48 , pp. 6132-6142
    • Bargieri, D.Y.1    Rosa, D.S.2    Braga, C.J.3    Carvalho, B.O.4    Costa, F.T.5    Espindola, N.M.6
  • 19
    • 0033830013 scopus 로고    scopus 로고
    • The synthetic, oxidized C-terminal fragment of the Plasmodium berghei circumsporozoite protein elicits a high protective response
    • Roggero M.A., Meraldi V., Lopez J.A., Eberl G., Romero J.C., Matile H., et al. The synthetic, oxidized C-terminal fragment of the Plasmodium berghei circumsporozoite protein elicits a high protective response. Eur J Immunol 30 Sep (9) (2000) 2679-2685
    • (2000) Eur J Immunol , vol.30 , Issue.Sep 9 , pp. 2679-2685
    • Roggero, M.A.1    Meraldi, V.2    Lopez, J.A.3    Eberl, G.4    Romero, J.C.5    Matile, H.6
  • 20
    • 0037726802 scopus 로고    scopus 로고
    • OM-174, a new adjuvant with a potential for human use, induces a protective response when administered with the synthetic C-terminal fragment 242-310 from the circumsporozoite protein of Plasmodium berghei
    • Meraldi V., Audran R., Romero J.F., Brossard V., Bauer J., Lopez J.A., et al. OM-174, a new adjuvant with a potential for human use, induces a protective response when administered with the synthetic C-terminal fragment 242-310 from the circumsporozoite protein of Plasmodium berghei. Vaccine 21 Jun 2 (19-20) (2003) 2485-2491
    • (2003) Vaccine , vol.21 , Issue.Jun 2 19-20 , pp. 2485-2491
    • Meraldi, V.1    Audran, R.2    Romero, J.F.3    Brossard, V.4    Bauer, J.5    Lopez, J.A.6
  • 21
    • 15044347193 scopus 로고    scopus 로고
    • A strong CD8+ T cell response is elicited using the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei together with the adjuvant QS-21: quantitative and phenotypic comparison with the vaccine model of irradiated sporozoites
    • Meraldi V., Romero J.F., Kensil C., and Corradin G. A strong CD8+ T cell response is elicited using the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei together with the adjuvant QS-21: quantitative and phenotypic comparison with the vaccine model of irradiated sporozoites. Vaccine 23 Apr 15 (21) (2005) 2801-2812
    • (2005) Vaccine , vol.23 , Issue.Apr 15 21 , pp. 2801-2812
    • Meraldi, V.1    Romero, J.F.2    Kensil, C.3    Corradin, G.4
  • 22
    • 0024954612 scopus 로고
    • Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria
    • Romero P., Maryanski J.L., Corradin G., Nussenzweig R.S., Nussenzweig V., and Zavala F. Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria. Nature 341 Sep 28 (6240) (1989) 323-326
    • (1989) Nature , vol.341 , Issue.Sep 28 6240 , pp. 323-326
    • Romero, P.1    Maryanski, J.L.2    Corradin, G.3    Nussenzweig, R.S.4    Nussenzweig, V.5    Zavala, F.6
  • 23
    • 0029072487 scopus 로고
    • CD8+ T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: evidence that localization of peptide-specific CTLs is crucial for protection against malaria
    • Renggli J., Valmori D., Romero J.F., Eberl G., Romero P., Betschart B., et al. CD8+ T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: evidence that localization of peptide-specific CTLs is crucial for protection against malaria. Immunol Lett 46 May (1-2) (1995) 199-205
    • (1995) Immunol Lett , vol.46 , Issue.May 1-2 , pp. 199-205
    • Renggli, J.1    Valmori, D.2    Romero, J.F.3    Eberl, G.4    Romero, P.5    Betschart, B.6
  • 24
    • 0034254649 scopus 로고    scopus 로고
    • The complexity of protective immunity against liver-stage malaria
    • Doolan D.L., and Hoffman S.L. The complexity of protective immunity against liver-stage malaria. J Immunol 165 Aug 1 (3) (2000) 1453-1462
    • (2000) J Immunol , vol.165 , Issue.Aug 1 3 , pp. 1453-1462
    • Doolan, D.L.1    Hoffman, S.L.2
  • 25
    • 35348936104 scopus 로고    scopus 로고
    • IL-12p40-independent induction of protective immunity upon multiple Plasmodium berghei irradiated sporozoite immunizations
    • Romero J.F., Ibrahim G.H., Renggli J., Himmelrich H., Graber P., and Corradin G. IL-12p40-independent induction of protective immunity upon multiple Plasmodium berghei irradiated sporozoite immunizations. Parasite Immunol 29 Nov (11) (2007) 541-548
    • (2007) Parasite Immunol , vol.29 , Issue.Nov 11 , pp. 541-548
    • Romero, J.F.1    Ibrahim, G.H.2    Renggli, J.3    Himmelrich, H.4    Graber, P.5    Corradin, G.6
  • 26
    • 51449101667 scopus 로고    scopus 로고
    • Cellular effector mechanisms against Plasmodium liver stages
    • Frevert U., and Nardin E. Cellular effector mechanisms against Plasmodium liver stages. Cell Microbiol 10 Oct (10) (2008) 1956-1967
    • (2008) Cell Microbiol , vol.10 , Issue.Oct 10 , pp. 1956-1967
    • Frevert, U.1    Nardin, E.2
  • 28
    • 0032489830 scopus 로고    scopus 로고
    • Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity
    • Giuliani M.M., Del Giudice G., Giannelli V., Dougan G., Douce G., Rappuoli R., et al. Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity. J Exp Med 187 Apr 6 (7) (1998) 1123-1132
    • (1998) J Exp Med , vol.187 , Issue.Apr 6 7 , pp. 1123-1132
    • Giuliani, M.M.1    Del Giudice, G.2    Giannelli, V.3    Dougan, G.4    Douce, G.5    Rappuoli, R.6
  • 29
    • 0031588944 scopus 로고    scopus 로고
    • Isolation and characterization of mouse nasal-associated lymphoid tissue
    • Asanuma H., Thompson A.H., Iwasaki T., Sato Y., Inaba Y., Aizawa C., et al. Isolation and characterization of mouse nasal-associated lymphoid tissue. J Immunol Methods 202 Mar 28 (2) (1997) 123-131
    • (1997) J Immunol Methods , vol.202 , Issue.Mar 28 2 , pp. 123-131
    • Asanuma, H.1    Thompson, A.H.2    Iwasaki, T.3    Sato, Y.4    Inaba, Y.5    Aizawa, C.6
  • 31
    • 0004170486 scopus 로고    scopus 로고
    • A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group
    • Stoute J.A., Slaoui M., Heppner D.G., Momin P., Kester K.E., Desmons P., et al. A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group. N Engl J Med 336 Jan 9 (2) (1997) 86-91
    • (1997) N Engl J Med , vol.336 , Issue.Jan 9 2 , pp. 86-91
    • Stoute, J.A.1    Slaoui, M.2    Heppner, D.G.3    Momin, P.4    Kester, K.E.5    Desmons, P.6
  • 32
    • 0032538597 scopus 로고    scopus 로고
    • Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine
    • Wang R., Doolan D.L., Le T.P., Hedstrom R.C., Coonan K.M., Charoenvit Y., et al. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 282 Oct 16 (5388) (1998) 476-480
    • (1998) Science , vol.282 , Issue.Oct 16 5388 , pp. 476-480
    • Wang, R.1    Doolan, D.L.2    Le, T.P.3    Hedstrom, R.C.4    Coonan, K.M.5    Charoenvit, Y.6
  • 33
    • 0033182171 scopus 로고    scopus 로고
    • Pre-erythrocytic malaria vaccine: mechanisms of protective immunity and human vaccine trials
    • Nardin E., Zavala F., Nussenzweig V., and Nussenzweig R.S. Pre-erythrocytic malaria vaccine: mechanisms of protective immunity and human vaccine trials. Parassitologia 41 Sep (1-3) (1999) 397-402
    • (1999) Parassitologia , vol.41 , Issue.Sep 1-3 , pp. 397-402
    • Nardin, E.1    Zavala, F.2    Nussenzweig, V.3    Nussenzweig, R.S.4
  • 34
    • 10444286628 scopus 로고    scopus 로고
    • Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720
    • Walther M., Dunachie S., Keating S., Vuola J.M., Berthoud T., Schmidt A., et al. Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720. Vaccine 23 Jan 4 (7) (2005) 857-864
    • (2005) Vaccine , vol.23 , Issue.Jan 4 7 , pp. 857-864
    • Walther, M.1    Dunachie, S.2    Keating, S.3    Vuola, J.M.4    Berthoud, T.5    Schmidt, A.6
  • 35
    • 38449108512 scopus 로고    scopus 로고
    • The acquired immune response to the mucosal adjuvant LTK63 imprints the mouse lung with a protective signature
    • Tritto E., Muzzi A., Pesce I., Monaci E., Nuti S., Galli G., et al. The acquired immune response to the mucosal adjuvant LTK63 imprints the mouse lung with a protective signature. J Immunol 179 Oct 15 (8) (2007) 5346-5357
    • (2007) J Immunol , vol.179 , Issue.Oct 15 8 , pp. 5346-5357
    • Tritto, E.1    Muzzi, A.2    Pesce, I.3    Monaci, E.4    Nuti, S.5    Galli, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.