Vaccine-like immunity against malaria by repeated causal-prophylactic treatment of liver-stage plasmodium parasites

Journal of Infectious Diseases

Volumn 199, Issue 6, 2009, Pages 899-903

  Putrianti, Elyzana Dewi ^a,c   Silvie, Olivier ^a,c   Kordes, Maximilian ^a   Borrmann, Steffen ^b   Matuschewski, Kai ^a,c  

^a Department of Parasitology ^*  (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PRIMAQUINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN MALARIA; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNITY; IMMUNIZATION; LIFE CYCLE; MALARIA; MOUSE; NONHUMAN; PARASITE DEVELOPMENT; PLASMODIUM; PLASMODIUM BERGHEI; PLASMODIUM YOELII; PRIORITY JOURNAL; PROPHYLAXIS; SPOROZOITE;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; LIVER; MALARIA; MALARIA VACCINES; MICE; MICE, INBRED C57BL; PLASMODIUM; PLASMODIUM YOELII;

EID: 65649092055     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/597121     Document Type: Article

References (15)

1. Nussenzweig RS, Vanderberg J, Most H, Orton C. Protective immunity produced by the injection of X-irradiated sporozoites of Plasmodium berghei. Nature 1967; 216:160-2.
2. Hoffman SL, Goh LM, Luke TC, et al. Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. J Infect Dis 2002; 185:1155-64.
3. Mueller AK, Labaied M, Kappe SHI, Matuschewski K. Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature 2005; 433:164-7.
4. Beaudoin RL, Strome CPA, Mitchell F, Tubergren TA. Plasmodium berghei: immunization of mice against the ANKA strain using the unaltered sporozoites as an antigen. Exp Parasitol 1977; 42:1-5.
5. Orjih AU, Cochrane AH, Nussenzweig RS. Comparative studies on the immunogenicity of infective and attenuated sporozoites of Plasmodium berghei. Trans R Soc Trop Med Hyg 1982; 76:57-61.
6. Belnoue E, Costa FTM, Frankenberg T, et al. Protective T cell immunity against malaria liver stages after vaccination with live sporozoites under chloroquine treatment. J Immunol 2004; 172:2487-95.
7. Hafalla JCR, Rai U, Bernal-Rubio, Rodriguez A, Zavala F. Efficient development of Plasmodium liver stage-specific memoryCD8- T cells during the course of blood-stage malarial infection. J Infect Dis 2007; 196: 1827-35.
8. Weiss WR, Oloo AJ, Johnson A, et al. Daily primaquine is effective for prophylaxis against falciparum malaria in Kenya: comparison with mefloquine, doxycycline, and chloroquine plus proguanil. J Infect Dis 1995; 171:1569-75.
9. Lell B, Faucher, JF, Missinou MA, et al. Malaria chemoprophylaxis with tafenoquine: a randomised study. Lancet 2000; 355:2041-5.
10. Scheller LF, Azad AF. Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites. Proc Natl Acad Sci U S A 1995; 92:4066-8.
11. Mueller AK, Deckert M, Heiss K, et al. Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cells. Am J Pathol 2007; 171:107-15.
12. Chakravarty S, Cockburn IA, Kuk S, et al. CD8- T lymphocytes protective against malaria liver stages are primed in the skin-draining lymph nodes. Nat Med 2007; 13:1035-41.
13. Shapiro TA, Ranasinha CD, Kumar N, Barditch-Crovo P. Prophylactic activity of atovaquone against Plasmodium falciparum in humans. Am J Trop Med Hyg 1999; 60:831-6.
14. Purcell LA, Yanow SK, Lee M, Spithill TW, Rodriguez A. Chemical attenuation of Plasmodium berghei sporozoites induces sterile immunity in mice. Infect Immun 2008; 76:1193-9.
15. Hoffman SL, Oster CN, Plowe CV, et al. Naturally acquired antibodies to sporozoites do not prevent malaria: vaccine development implications. Science 1987; 237:639-42.