Dynamics and function of langerhans cells in vivo: Dermal dendritic cells colonize lymph node areasdistinct from slower migrating langerhans cells

Immunity

Volumn 22, Issue 5, 2005, Pages 643-654

  Kissenpfennig, Adrien ^a   Henri, Sandrine ^a   Dubois, Bertrand ^b   Laplace Builhé, Corinne ^c   Perrin, Pierre ^a   Romani, Nikolaus ^d   Tripp, Christoph H ^d   Douillard, Patrice ^e   Leserman, Lee ^a   Kaiserlian, Dominique ^b   Saeland, Sem ^e   Davoust, Jean ^c   Malissen, Bernard ^a  

^a CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^b University Lyon i   (France)

^c GÉNÉTHON   (France)

^d INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^e MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8ALPHA ANTIGEN; DIPHTHERIA TOXIN; ENHANCED GREEN FLUORESCENT PROTEIN; GENE PRODUCT; HAPTEN; LANGERIN PROTEIN; PROTEIN; RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL FUNCTION; CELL MIGRATION; CELL MOTILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITIC CELL; EFFECTOR CELL; GENE FUNCTION; IMMUNIZATION; IN VIVO STUDY; INFLAMMATION; LANGERHANS CELL; LYMPH NODE; LYMPHOID ORGAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN CELL; T LYMPHOCYTE; THYMUS;

EID: 21144444056     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2005.04.004     Document Type: Article

References (43)

1. H. Akiba, J. Kehren, M.T. Ducluzeau, M. Krasteva, F. Horand, D. Kaiserlian, F. Kaneko, and J.F. Nicolas Skin inflammation during contact hypersensitivity is mediated by early recruitment of CD8+ T cytotoxic 1 cells inducing keratinocyte apoptosis J. Immunol. 168 2002 3079 3087
2. R.S. Allan, C.M. Smith, G.T. Belz, A.L. van Lint, L.M. Wakim, W.R. Heath, and F.R. Carbone Epidermal viral immunity induced by CD8alpha+ dendritic cells but not by Langerhans cells Science 301 2003 1925 1928
3. F. Anjuere, P. Martin, I. Ferrero, M.L. Fraga, G.M. del Hoyo, N. Wright, and C. Ardavin Definition of dendritic cell subpopulations present in the spleen, Peyer's patches, lymph nodes, and skin of the mouse Blood 93 1999 590 598
4. C. Asselin-Paturel, G. Brizard, J.J. Pin, F. Briere, and G. Trinchieri Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody J. Immunol. 171 2003 6466 6477
5. S. Bacci, P. Alard, R. Dai, T. Nakamura, and J.W. Streilein High and low doses of haptens dictate whether dermal or epidermal antigen-presenting cells promote contact hypersensitivity Eur. J. Immunol. 27 1997 442 448
6. G.T. Belz, C.M. Smith, D. Eichner, K. Shortman, G. Karupiah, F.R. Carbone, and W.R. Heath Cutting edge: conventional CD8alpha(+) dendritic cells are generally involved in priming CTL immunity to viruses J. Immunol. 172 2004 1996 2000
7. M. Breel, R.E. Mebius, and G. Kraal Dendritic cells of the mouse recognized by two monoclonal antibodies Eur. J. Immunol. 17 1987 1555 1559
8. F.R. Carbone, G.T. Belz, and W.R. Heath Transfer of antigen between migrating and lymph node-resident DCs in peripheral T-cell tolerance and immunity Trends Immunol. 25 2004 655 658
9. A. Dakic, Q.X. Shao, A. D'Amico, M. O'Keeffe, W.F. Chen, K. Shortman, and L. Wu Development of the dendritic cell system during mouse ontogeny J. Immunol. 172 2004 1018 1027
10. J.M. den Haan, S.M. Lehar, and M.J. Bevan CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo J. Exp. Med. 192 2000 1685 1696
11. J.E. Gretz, C.C. Norbury, A.O. Anderson, A.E. Proudfoot, and S. Shaw Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex J. Exp. Med. 192 2000 1425 1440
12. W.R. Heath, and J.A. Villadangos No driving without a license Nat. Immunol. 6 2005 125 126
13. H. Hemmi, M. Yoshino, H. Yamazaki, M. Naito, T. Iyoda, Y. Omatsu, S. Shimoyama, J.J. Letterio, T. Nakabayashi, and H. Tagaya Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-beta1-dependent cells Int. Immunol. 13 2001 695 704
14. S. Henri, D. Vremec, A. Kamath, J. Waithman, S. Williams, C. Benoist, K. Burnham, S. Saeland, E. Handman, and K. Shortman The dendritic cell populations of mouse lymph nodes J. Immunol. 167 2001 741 748
15. E.C. Hoefsmit, A.M. Duijvestijn, and E.W. Kamperdijk Relation between langerhans cells, veiled cells, and interdigitating cells Immunobiology 161 1982 255 265
16. A.A. Itano, and M.K. Jenkins Antigen presentation to naive CD4 T cells in the lymph node Nat. Immunol. 4 2003 733 739
17. A.A. Itano, S.J. McSorley, R.L. Reinhardt, B.D. Ehst, E. Ingulli, A.Y. Rudensky, and M.K. Jenkins Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity Immunity 19 2003 47 57
18. A. Iwasaki The importance of CD11b+ dendritic cells in CD4+ T cell activation in vivo: with help from interleukin 1 J. Exp. Med. 198 2003 185 190
19. S. Jung, D. Unutmaz, P. Wong, G. Sano, K. De los Santos, T. Sparwasser, S. Wu, S. Vuthoori, K. Ko, and F. Zavala In vivo depletion of CD11c(+) dendritic cells abrogates priming of CD8(+) T cells by exogenous cell-associated antigens Immunity 17 2002 211 220
20. A.T. Kamath, S. Henri, F. Battye, D.F. Tough, and K. Shortman Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs Blood 100 2002 1734 1741
21. J. Kehren, C. Desvignes, M. Krasteva, M.T. Ducluzeau, O. Assossou, F. Horand, M. Hahne, D. Kagi, D. Kaiserlian, and J.F. Nicolas Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity J. Exp. Med. 189 1999 779 786
22. A. Kissenpfennig, S. Ait-Yahia, V. Clair-Moninot, H. Stossel, E. Badell, Y. Bordat, J.L. Pooley, T. Lang, E. Prina, and I. Coste Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function Mol. Cell. Biol. 25 2005 88 99
23. R.L. Lindquist, G. Shakhar, D. Dudziak, H. Wardemann, T. Eisenreich, M.L. Dustin, and M.C. Nussenzweig Visualizing dendritic cell networks in vivo Nat. Immunol. 5 2004 1243 1250
24. D. Mayerova, E.A. Parke, L.S. Bursch, O.A. Odumade, and K.A. Hogquist Langerhans cells activate naive self-antigen-specific CD8 T cells in the steady state Immunity 21 2004 391 400
25. A.D. McLellan, M. Kapp, A. Eggert, C. Linden, U. Bommhardt, E.B. Brocker, U. Kammerer, and E. Kampgen Anatomic location and T-cell stimulatory functions of mouse dendritic cell subsets defined by CD4 and CD8 expression Blood 99 2002 2084 2093
26. M. Merad, M.G. Manz, H. Karsunky, A. Wagers, W. Peters, I. Charo, I.L. Weissman, J.G. Cyster, and E.G. Engleman Langerhans cells renew in the skin throughout life under steady-state conditions Nat. Immunol. 3 2002 1135 1141
27. M. Merad, P. Hoffmann, E. Ranheim, S. Slaymaker, M.G. Manz, S.A. Lira, I. Charo, D.N. Cook, I.L. Weissman, S. Strober, and E.G. Engleman Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease Nat. Med. 10 2004 510 517
28. B.J. Nickoloff, and Y. Naidu Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin J. Am. Acad. Dermatol. 30 1994 535 546
29. H.C. Probst, J. Lagnel, G. Kollias, and M. van den Broek Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance Immunity 18 2003 713 720
30. G. Ratzinger, P. Stoitzner, S. Ebner, M.B. Lutz, G.T. Layton, C. Rainer, R.M. Senior, J.M. Shipley, P. Fritsch, G. Schuler, and N. Romani Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin J. Immunol. 168 2002 4361 4371
31. C. Ruedl, P. Koebel, M. Bachmann, M. Hess, and K. Karjalainen Anatomical origin of dendritic cells determines their life span in peripheral lymph nodes J. Immunol. 165 2000 4910 4916
32. R. Sporri, and E.S.C. Reis Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4(+) T cell populations lacking helper function Nat. Immunol. 6 2005 163 170
33. R.M. Steinman, and M.C. Nussenzweig Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance Proc. Natl. Acad. Sci. USA 99 2002 351 358
34. P. Stoitzner, K. Pfaller, H. Stossel, and N. Romani A close-up view of migrating Langerhans cells in the skin J. Invest. Dermatol. 118 2002 117 125
35. P. Stoitzner, S. Holzmann, A.D. McLellan, L. Ivarsson, H. Stossel, M. Kapp, U. Kammerer, P. Douillard, E. Kampgen, and F. Koch Visualization and characterization of migratory Langerhans cells in murine skin and lymph nodes by antibodies against Langerin/CD207 J. Invest. Dermatol. 120 2003 266 274
36. S. Sullivan, P.R. Bergstresser, R.E. Tigelaar, and J.W. Streilein Induction and regulation of contact hypersensitivity by resident, bone marrow-derived, dendritic epidermal cells: Langerhans cells and Thy-1+ epidermal cells J. Immunol. 137 1986 2460 2467
37. K. Takahara, Y. Omatsu, Y. Yashima, Y. Maeda, S. Tanaka, T. Iyoda, B.E. Clausen, K. Matsubara, J. Letterio, and R.M. Steinman Identification and expression of mouse Langerin (CD207) in dendritic cells Int. Immunol. 14 2002 433 444
38. R.E. Tigelaar, P.R. Bergstresser, L.M. Lonsberry, C. Elmets, P.J. Wood, and J.W. Streilen Oral ingestion of epicutaneously applied hapten in mice may unwittingly induce down-regulation of contact hypersensitivity J. Immunol. 129 1982 1898 1904
39. J. Valladeau, O. Ravel, C. Dezutter-Dambuyant, K. Moore, M. Kleijmeer, Y. Liu, V. Duvert-Frances, C. Vincent, D. Schmitt, and J. Davoust Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules Immunity 12 2000 71 81
40. J. Valladeau, V. Clair-Moninot, C. Dezutter-Dambuyant, J.J. Pin, A. Kissenpfennig, M.G. Mattei, S. Ait-Yahia, E.E. Bates, B. Malissen, and F. Koch Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues J. Immunol. 168 2002 782 792
41. D. Vremec, J. Pooley, H. Hochrein, L. Wu, and K. Shortman CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen J. Immunol. 164 2000 2978 2986
42. N.S. Wilson, D. El-Sukkari, G.T. Belz, C.M. Smith, R.J. Steptoe, W.R. Heath, K. Shortman, and J.A. Villadangos Most lymphoid organ dendritic cell types are phenotypically and functionally immature Blood 102 2003 2187 2194
43. X. Zhao, E. Deak, K. Soderberg, M. Linehan, D. Spezzano, J. Zhu, D.M. Knipe, and A. Iwasaki Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2 J. Exp. Med. 197 2003 153 162