Human antibodies against Plasmodium falciparum liver-stage antigen 3 cross-react with Plasmodium yoelii preerythrocytic-stage epitopes and inhibit sporozoite invasion in vitro and in vivo

Infection and Immunity

Volumn 69, Issue 6, 2001, Pages 3845-3852

  Brahimi, K ^a   Badell, E ^a   Sauzet, J P ^a   BenMohamed, L ^a   Daubersies, P ^a   Guerin Marchand C ^a   Snounou, G ^a   Druilhe, P ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; ANTIGEN 3; EPITOPE; PROTEIN LSA3; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANTIBODY AFFINITY; ANTIBODY RESPONSE; ARTICLE; CELL INVASION; CONTROLLED STUDY; CROSS REACTION; HUMAN; HUMAN CELL; IMMUNITY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; MALARIA; MOUSE; NONHUMAN; PASSIVE IMMUNIZATION; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SPOROZOITE;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; CROSS REACTIONS; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; ERYTHROCYTES; HEPATOCYTES; HUMANS; MALARIA; MALARIA, FALCIPARUM; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; PAN TROGLODYTES; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; RECOMBINANT PROTEINS;

EID: 0035019519     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.6.3845-3952.2001     Document Type: Article

References (33)

1. Lipopeptide immunization without adjuvant induces potent and long-lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees
2. High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules
3. A novel Plasmodium falciparum sporozoite and liver stage antigen (SALSA) defines major B, Th and CTL epitopes
4. Fast immunopurification of small amounts of specific antibodies on peptides bound to ELISA plates
5. A protective monoclonal antibody recognizes a variant-specific epitope in the precursor of the major merozoite surface antigen of the rodent malarial parasite Plasmodium yoelii
6. Inability of malaria vaccine to induce antibodies to a protective epitope within its sequence
7. Monoclonal, but not polyclonal, antibodies protect against Plasmodium yoelii sporozoites
8. Plasmodium yoelii: 17-kDa hepatic and erythrocytic stage protein is the target of an inhibitory monoclonal antibody
9. Immunization of man against sporozoite-induced falciparum malaria
10. Cloning of cDNAs that code for Plasmodium chabaudi antigens of the erythrocytic forms and crosshybridize with P. falciparum
11. Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3
12. Primary structure of the merozoite surface antigen 1 of Plasmodium vivax reveals sequences conserved between different Plasmodium species
13. Identification and characterisation of the protective hepatocyte erythrocyte protein 17 kDa gene of Plasmodium yoelii, homolog of Plasmodium falciparum exported protein 1
14. From sporozoite to liver stages: The saga of the irradiated sporozoite vaccine
15. Levels of antibodies to Plasmodium falciparum sporozoite surface antigens reflect malaria transmission rates and are persistent in the absence of reinfections
16. Immunity to liver stages
17. Cloning and characterization of a novel Plasmodium falciparum sporozoite surface antigen, STARP
18. Antibodies against thrombospondin-related anonymous protein do not inhibit Plasmodium sporozoite infectivity in vivo
19. Activity of human volunteer sera to candidate Plasmodium falciparum circumsporozoite protein vaccines in the inhibition of sporozoite invasion assay of human hepatoma cells and hepatocytes
20. Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells: An in vitro assay of protective antibodies
21. How to select P. falciparum pre-erythrocytic antigens in an expression library without defined probe
22. Effect of antibodies to recombinant and synthetic peptides on development of Plasmodium falciparum sporozoites in vitro
23. Evaluation of an in vitro assay aimed at measuring protective antibodies against sporozoites
24. Solid-phase peptide synthesis. The synthesis of a tetrapeptide
25. Plasmodium falciparum sporozoite invasion is inhibited by naturally acquired or experimentally induced polyclonal antibodies to the STARP antigen
26. Serum antibody immunoglobulin G of mice convalescent from Plasmodium yoelii infection inhibits growth of Plasmodium falciparum in vitro: Blood stage antigens of P. falciparum involved in interspecies cross-reactive inhibition of parasite growth
27. Characterization of Plasmodium falciparum sporozoite surface protein 2
28. Preventing sporozoite invasion of hepatocytes
29. Plasmodium berghei sporozoite invasion is blocked in vitro by sporozoite-immobilizing antibodies
30. Long-term efficacy and immune responses following immunization with the RTS,S malaria vaccine
31. TRAP is necessary for gliding motility and infectivity of plasmodium sporozoites
32. Cloning and cross-species comparison of the thrombospondin-related anonymous protein (TRAP) gene from Plasmodium knowlesi, Plasmodium vivax and Plasmodium gallinaceum